Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY |
| Enrichment Score (ES) | 0.44555837 |
| Normalized Enrichment Score (NES) | 1.0272112 |
| Nominal p-value | 0.3622449 |
| FDR q-value | 0.37387794 |
| FWER p-Value | 0.777 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 142 | 3.835 | 0.0612 | Yes |
| 2 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 146 | 3.815 | 0.1258 | Yes |
| 3 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 221 | 3.363 | 0.1808 | Yes |
| 4 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 276 | 3.100 | 0.2319 | Yes |
| 5 | SRXN1 | sulfiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:16132] | 395 | 2.624 | 0.2732 | Yes |
| 6 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 671 | 2.029 | 0.3001 | Yes |
| 7 | SELENOS | selenoprotein S [Source:HGNC Symbol;Acc:HGNC:30396] | 866 | 1.704 | 0.3238 | Yes |
| 8 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 870 | 1.699 | 0.3525 | Yes |
| 9 | ABCC1 | ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51] | 1106 | 1.469 | 0.3711 | Yes |
| 10 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 1268 | 1.337 | 0.3894 | Yes |
| 11 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1913 | 0.953 | 0.3881 | Yes |
| 12 | G6PD | glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] | 2137 | 0.863 | 0.3968 | Yes |
| 13 | EGLN2 | egl-9 family hypoxia inducible factor 2 [Source:HGNC Symbol;Acc:HGNC:14660] | 2197 | 0.839 | 0.4094 | Yes |
| 14 | SCAF4 | SR-related CTD associated factor 4 [Source:HGNC Symbol;Acc:HGNC:19304] | 2490 | 0.738 | 0.4140 | Yes |
| 15 | MSRA | methionine sulfoxide reductase A [Source:HGNC Symbol;Acc:HGNC:7377] | 2496 | 0.735 | 0.4263 | Yes |
| 16 | NQO1 | NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874] | 2508 | 0.732 | 0.4384 | Yes |
| 17 | LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Source:HGNC Symbol;Acc:HGNC:17955] | 2671 | 0.678 | 0.4456 | Yes |
| 18 | PRNP | prion protein [Source:HGNC Symbol;Acc:HGNC:9449] | 3867 | 0.387 | 0.4199 | No |
| 19 | HHEX | hematopoietically expressed homeobox [Source:HGNC Symbol;Acc:HGNC:4901] | 4730 | 0.231 | 0.4005 | No |
| 20 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3434] | 5131 | 0.173 | 0.3926 | No |
| 21 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9497 | 0.000 | 0.2748 | No |
| 22 | MGST1 | microsomal glutathione S-transferase 1 [Source:HGNC Symbol;Acc:HGNC:7061] | 11811 | 0.000 | 0.2124 | No |
| 23 | PDLIM1 | PDZ and LIM domain 1 [Source:HGNC Symbol;Acc:HGNC:2067] | 17653 | 0.000 | 0.0547 | No |
| 24 | IPCEF1 | interaction protein for cytohesin exchange factors 1 [Source:HGNC Symbol;Acc:HGNC:21204] | 17817 | 0.000 | 0.0503 | No |
| 25 | MPO | myeloperoxidase [Source:HGNC Symbol;Acc:HGNC:7218] | 18890 | 0.000 | 0.0213 | No |
| 26 | NDUFB4 | NADH:ubiquinone oxidoreductase subunit B4 [Source:HGNC Symbol;Acc:HGNC:7699] | 22662 | 0.000 | -0.0805 | No |
| 27 | PRDX2 | peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353] | 28318 | -0.159 | -0.2304 | No |
| 28 | GLRX2 | glutaredoxin 2 [Source:HGNC Symbol;Acc:HGNC:16065] | 28700 | -0.214 | -0.2371 | No |
| 29 | GSR | glutathione-disulfide reductase [Source:HGNC Symbol;Acc:HGNC:4623] | 29195 | -0.281 | -0.2457 | No |
| 30 | ATOX1 | antioxidant 1 copper chaperone [Source:HGNC Symbol;Acc:HGNC:798] | 29295 | -0.294 | -0.2434 | No |
| 31 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 29601 | -0.340 | -0.2458 | No |
| 32 | STK25 | serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404] | 30114 | -0.415 | -0.2526 | No |
| 33 | HMOX2 | heme oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:5014] | 30750 | -0.515 | -0.2611 | No |
| 34 | FTL | ferritin light chain [Source:HGNC Symbol;Acc:HGNC:3999] | 30770 | -0.518 | -0.2528 | No |
| 35 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31053 | -0.567 | -0.2508 | No |
| 36 | FES | FES proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3657] | 31773 | -0.709 | -0.2582 | No |
| 37 | OXSR1 | oxidative stress responsive kinase 1 [Source:HGNC Symbol;Acc:HGNC:8508] | 32106 | -0.787 | -0.2538 | No |
| 38 | GCLC | glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311] | 33446 | -1.152 | -0.2704 | No |
| 39 | TXNRD2 | thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155] | 33520 | -1.177 | -0.2524 | No |
| 40 | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2 [Source:HGNC Symbol;Acc:HGNC:7708] | 33581 | -1.195 | -0.2338 | No |
| 41 | NDUFA6 | NADH:ubiquinone oxidoreductase subunit A6 [Source:HGNC Symbol;Acc:HGNC:7690] | 34013 | -1.347 | -0.2226 | No |
| 42 | PTPA | protein phosphatase 2 phosphatase activator [Source:HGNC Symbol;Acc:HGNC:9308] | 34036 | -1.355 | -0.2002 | No |
| 43 | PRDX6 | peroxiredoxin 6 [Source:HGNC Symbol;Acc:HGNC:16753] | 34302 | -1.457 | -0.1827 | No |
| 44 | PFKP | phosphofructokinase, platelet [Source:HGNC Symbol;Acc:HGNC:8878] | 34371 | -1.490 | -0.1593 | No |
| 45 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 35726 | -2.257 | -0.1576 | No |
| 46 | LSP1 | lymphocyte specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707] | 35761 | -2.288 | -0.1197 | No |
| 47 | CDKN2D | cyclin dependent kinase inhibitor 2D [Source:HGNC Symbol;Acc:HGNC:1790] | 36492 | -3.016 | -0.0883 | No |
| 48 | MBP | myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925] | 36518 | -3.058 | -0.0371 | No |
| 49 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 36555 | -3.099 | 0.0144 | No |
