Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.greenbergcls.cls #WT_LPS_versus_WT_NA.greenbergcls.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | greenbergcls.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HALLMARK_SPERMATOGENESIS |
| Enrichment Score (ES) | -0.6573555 |
| Normalized Enrichment Score (NES) | -1.3985465 |
| Nominal p-value | 0.0021367522 |
| FDR q-value | 0.04610088 |
| FWER p-Value | 0.235 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DPEP3 | dipeptidase 3 [Source:HGNC Symbol;Acc:HGNC:23029] | 401 | 2.599 | 0.0138 | No |
| 2 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 532 | 2.289 | 0.0321 | No |
| 3 | ELOVL3 | ELOVL fatty acid elongase 3 [Source:HGNC Symbol;Acc:HGNC:18047] | 605 | 2.136 | 0.0504 | No |
| 4 | TLE4 | TLE family member 4, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11840] | 1679 | 1.066 | 0.0315 | No |
| 5 | PGS1 | phosphatidylglycerophosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:30029] | 2004 | 0.917 | 0.0315 | No |
| 6 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 2229 | 0.825 | 0.0332 | No |
| 7 | STAM2 | signal transducing adaptor molecule 2 [Source:HGNC Symbol;Acc:HGNC:11358] | 2249 | 0.817 | 0.0405 | No |
| 8 | PAPOLB | poly(A) polymerase beta [Source:HGNC Symbol;Acc:HGNC:15970] | 2453 | 0.749 | 0.0421 | No |
| 9 | OAZ3 | ornithine decarboxylase antizyme 3 [Source:HGNC Symbol;Acc:HGNC:8097] | 2514 | 0.730 | 0.0474 | No |
| 10 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 2763 | 0.647 | 0.0469 | No |
| 11 | CSNK2A2 | casein kinase 2 alpha 2 [Source:HGNC Symbol;Acc:HGNC:2459] | 3393 | 0.484 | 0.0344 | No |
| 12 | TEKT2 | tektin 2 [Source:HGNC Symbol;Acc:HGNC:11725] | 3442 | 0.473 | 0.0376 | No |
| 13 | AGFG1 | ArfGAP with FG repeats 1 [Source:HGNC Symbol;Acc:HGNC:5175] | 3748 | 0.412 | 0.0333 | No |
| 14 | HSPA1L | heat shock protein family A (Hsp70) member 1 like [Source:HGNC Symbol;Acc:HGNC:5234] | 4326 | 0.299 | 0.0205 | No |
| 15 | ARL4A | ADP ribosylation factor like GTPase 4A [Source:HGNC Symbol;Acc:HGNC:695] | 5352 | 0.140 | -0.0059 | No |
| 16 | PIAS2 | protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311] | 5482 | 0.123 | -0.0082 | No |
| 17 | NAA11 | N-alpha-acetyltransferase 11, NatA catalytic subunit [Source:HGNC Symbol;Acc:HGNC:28125] | 5541 | 0.117 | -0.0087 | No |
| 18 | RAD17 | RAD17 checkpoint clamp loader component [Source:HGNC Symbol;Acc:HGNC:9807] | 5816 | 0.080 | -0.0153 | No |
| 19 | ACTL7B | actin like 7B [Source:HGNC Symbol;Acc:HGNC:162] | 5827 | 0.079 | -0.0148 | No |
| 20 | TSN | translin [Source:HGNC Symbol;Acc:HGNC:12379] | 6058 | 0.045 | -0.0206 | No |
| 21 | SCG5 | secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816] | 6573 | 0.000 | -0.0345 | No |
| 22 | SCG3 | secretogranin III [Source:HGNC Symbol;Acc:HGNC:13707] | 6575 | 0.000 | -0.0346 | No |
| 23 | ADCYAP1 | adenylate cyclase activating polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:241] | 7353 | 0.000 | -0.0556 | No |
| 24 | ART3 | ADP-ribosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:725] | 7458 | 0.000 | -0.0584 | No |
| 25 | CCNA1 | cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577] | 7562 | 0.000 | -0.0612 | No |
| 26 | ZC2HC1C | zinc finger C2HC-type containing 1C [Source:HGNC Symbol;Acc:HGNC:20354] | 8242 | 0.000 | -0.0796 | No |
| 27 | HOXB1 | homeobox B1 [Source:HGNC Symbol;Acc:HGNC:5111] | 8780 | 0.000 | -0.0941 | No |
| 28 | ADAM2 | ADAM metallopeptidase domain 2 [Source:HGNC Symbol;Acc:HGNC:198] | 8855 | 0.000 | -0.0961 | No |
| 29 | ADAD1 | adenosine deaminase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30713] | 9007 | 0.000 | -0.1002 | No |
| 30 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 9026 | 0.000 | -0.1007 | No |
| 31 | CRISP2 | cysteine rich secretory protein 2 [Source:HGNC Symbol;Acc:HGNC:12024] | 9065 | 0.000 | -0.1017 | No |
| 32 | NPY5R | neuropeptide Y receptor Y5 [Source:HGNC Symbol;Acc:HGNC:7958] | 9072 | 0.000 | -0.1019 | No |
| 33 | DMRT1 | doublesex and mab-3 related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:2934] | 9584 | 0.000 | -0.1157 | No |
| 34 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 9965 | 0.000 | -0.1260 | No |
| 35 | TULP2 | TUB like protein 2 [Source:HGNC Symbol;Acc:HGNC:12424] | 10132 | 0.000 | -0.1305 | No |
| 36 | CFTR | CF transmembrane conductance regulator [Source:HGNC Symbol;Acc:HGNC:1884] | 10166 | 0.000 | -0.1314 | No |
| 37 | LDHC | lactate dehydrogenase C [Source:HGNC Symbol;Acc:HGNC:6544] | 11086 | 0.000 | -0.1562 | No |
| 38 | CLGN | calmegin [Source:HGNC Symbol;Acc:HGNC:2060] | 11524 | 0.000 | -0.1681 | No |
| 39 | PRM2 | protamine 2 [Source:HGNC Symbol;Acc:HGNC:9448] | 11530 | 0.000 | -0.1682 | No |
| 40 | SEPTIN4 | septin 4 [Source:HGNC Symbol;Acc:HGNC:9165] | 11705 | 0.000 | -0.1729 | No |
| 41 | JAM3 | junctional adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:15532] | 12048 | 0.000 | -0.1822 | No |
| 42 | THEG | theg spermatid protein [Source:HGNC Symbol;Acc:HGNC:13706] | 12702 | 0.000 | -0.1998 | No |
| 43 | TCP11 | t-complex 11 [Source:HGNC Symbol;Acc:HGNC:11658] | 14380 | 0.000 | -0.2452 | No |
| 44 | TNP2 | transition protein 2 [Source:HGNC Symbol;Acc:HGNC:11952] | 14886 | 0.000 | -0.2589 | No |
| 45 | TNP1 | transition protein 1 [Source:HGNC Symbol;Acc:HGNC:11951] | 14888 | 0.000 | -0.2589 | No |
| 46 | HTR5A | 5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300] | 15604 | 0.000 | -0.2782 | No |
| 47 | CLVS1 | clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139] | 15725 | 0.000 | -0.2815 | No |
| 48 | MTNR1A | melatonin receptor 1A [Source:HGNC Symbol;Acc:HGNC:7463] | 15805 | 0.000 | -0.2836 | No |
| 49 | DCC | DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701] | 15985 | 0.000 | -0.2885 | No |
| 50 | GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [Source:HGNC Symbol;Acc:HGNC:24864] | 16441 | 0.000 | -0.3008 | No |
| 51 | AKAP4 | A-kinase anchoring protein 4 [Source:HGNC Symbol;Acc:HGNC:374] | 16589 | 0.000 | -0.3048 | No |
| 52 | DMC1 | DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927] | 16834 | 0.000 | -0.3114 | No |
| 53 | TKTL1 | transketolase like 1 [Source:HGNC Symbol;Acc:HGNC:11835] | 17144 | 0.000 | -0.3197 | No |
| 54 | HBZ | hemoglobin subunit zeta [Source:HGNC Symbol;Acc:HGNC:4835] | 17185 | 0.000 | -0.3208 | No |
| 55 | SYCP1 | synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487] | 17751 | 0.000 | -0.3361 | No |
| 56 | DNAJB8 | DnaJ heat shock protein family (Hsp40) member B8 [Source:HGNC Symbol;Acc:HGNC:23699] | 18393 | 0.000 | -0.3534 | No |
| 57 | IL12RB2 | interleukin 12 receptor subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:5972] | 19483 | 0.000 | -0.3829 | No |
| 58 | PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor [Source:HGNC Symbol;Acc:HGNC:17301] | 20606 | 0.000 | -0.4133 | No |
| 59 | SHE | Src homology 2 domain containing E [Source:HGNC Symbol;Acc:HGNC:27004] | 20722 | 0.000 | -0.4164 | No |
| 60 | H1-6 | H1.6 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4720] | 22532 | 0.000 | -0.4653 | No |
| 61 | MEP1B | meprin A subunit beta [Source:HGNC Symbol;Acc:HGNC:7020] | 22975 | 0.000 | -0.4773 | No |
| 62 | ACRV1 | acrosomal vesicle protein 1 [Source:HGNC Symbol;Acc:HGNC:127] | 23160 | 0.000 | -0.4823 | No |
| 63 | TSSK2 | testis specific serine kinase 2 [Source:HGNC Symbol;Acc:HGNC:11401] | 24267 | 0.000 | -0.5122 | No |
| 64 | SNAP91 | synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986] | 24386 | 0.000 | -0.5154 | No |
| 65 | CST8 | cystatin 8 [Source:HGNC Symbol;Acc:HGNC:2480] | 24422 | 0.000 | -0.5163 | No |
| 66 | ODF1 | outer dense fiber of sperm tails 1 [Source:HGNC Symbol;Acc:HGNC:8113] | 26051 | 0.000 | -0.5604 | No |
| 67 | ZNRF4 | zinc and ring finger 4 [Source:HGNC Symbol;Acc:HGNC:17726] | 26089 | 0.000 | -0.5614 | No |
| 68 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 26728 | 0.000 | -0.5787 | No |
| 69 | MAP7 | microtubule associated protein 7 [Source:HGNC Symbol;Acc:HGNC:6869] | 27003 | 0.000 | -0.5861 | No |
| 70 | SLC2A5 | solute carrier family 2 member 5 [Source:HGNC Symbol;Acc:HGNC:11010] | 27081 | 0.000 | -0.5882 | No |
| 71 | COIL | coilin [Source:HGNC Symbol;Acc:HGNC:2184] | 27172 | -0.009 | -0.5905 | No |
| 72 | NEFH | neurofilament heavy [Source:HGNC Symbol;Acc:HGNC:7737] | 27423 | -0.051 | -0.5968 | No |
| 73 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 27595 | -0.069 | -0.6007 | No |
| 74 | YBX2 | Y-box binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17948] | 27598 | -0.070 | -0.6001 | No |
| 75 | GAD1 | glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092] | 27807 | -0.097 | -0.6048 | No |
| 76 | PACRG | parkin coregulated [Source:HGNC Symbol;Acc:HGNC:19152] | 27883 | -0.106 | -0.6059 | No |
| 77 | IP6K1 | inositol hexakisphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:18360] | 28210 | -0.146 | -0.6133 | No |
| 78 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 28423 | -0.174 | -0.6174 | No |
| 79 | DDX25 | DEAD-box helicase 25 [Source:HGNC Symbol;Acc:HGNC:18698] | 28520 | -0.188 | -0.6182 | No |
| 80 | TALDO1 | transaldolase 1 [Source:HGNC Symbol;Acc:HGNC:11559] | 28915 | -0.242 | -0.6266 | No |
| 81 | PEBP1 | phosphatidylethanolamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8630] | 29064 | -0.264 | -0.6281 | No |
| 82 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 29327 | -0.299 | -0.6323 | No |
| 83 | DDX4 | DEAD-box helicase 4 [Source:HGNC Symbol;Acc:HGNC:18700] | 29715 | -0.355 | -0.6394 | No |
| 84 | PSMG1 | proteasome assembly chaperone 1 [Source:HGNC Symbol;Acc:HGNC:3043] | 30090 | -0.411 | -0.6456 | No |
| 85 | RPL39L | ribosomal protein L39 like [Source:HGNC Symbol;Acc:HGNC:17094] | 30272 | -0.438 | -0.6463 | No |
| 86 | TUBA3C | tubulin alpha 3c [Source:HGNC Symbol;Acc:HGNC:12408] | 30497 | -0.471 | -0.6479 | No |
| 87 | CLPB | caseinolytic mitochondrial matrix peptidase chaperone subunit B [Source:HGNC Symbol;Acc:HGNC:30664] | 30541 | -0.478 | -0.6446 | No |
| 88 | PHKG2 | phosphorylase kinase catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:8931] | 30801 | -0.524 | -0.6466 | No |
| 89 | GSTM3 | glutathione S-transferase mu 3 [Source:HGNC Symbol;Acc:HGNC:4635] | 31200 | -0.590 | -0.6518 | Yes |
| 90 | BRAF | B-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1097] | 31211 | -0.591 | -0.6464 | Yes |
| 91 | POMC | proopiomelanocortin [Source:HGNC Symbol;Acc:HGNC:9201] | 31338 | -0.614 | -0.6440 | Yes |
| 92 | SIRT1 | sirtuin 1 [Source:HGNC Symbol;Acc:HGNC:14929] | 31366 | -0.618 | -0.6388 | Yes |
| 93 | ZPBP | zona pellucida binding protein [Source:HGNC Symbol;Acc:HGNC:15662] | 31396 | -0.626 | -0.6337 | Yes |
| 94 | VDAC3 | voltage dependent anion channel 3 [Source:HGNC Symbol;Acc:HGNC:12674] | 31498 | -0.646 | -0.6303 | Yes |
| 95 | ACRBP | acrosin binding protein [Source:HGNC Symbol;Acc:HGNC:17195] | 31655 | -0.681 | -0.6280 | Yes |
| 96 | MAST2 | microtubule associated serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:19035] | 31703 | -0.690 | -0.6227 | Yes |
| 97 | PDHA2 | pyruvate dehydrogenase E1 subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8807] | 31812 | -0.716 | -0.6189 | Yes |
| 98 | PGK2 | phosphoglycerate kinase 2 [Source:HGNC Symbol;Acc:HGNC:8898] | 31999 | -0.763 | -0.6166 | Yes |
| 99 | MTOR | mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942] | 32018 | -0.766 | -0.6098 | Yes |
| 100 | CHFR | checkpoint with forkhead and ring finger domains [Source:HGNC Symbol;Acc:HGNC:20455] | 32086 | -0.782 | -0.6042 | Yes |
| 101 | MLLT10 | MLLT10 histone lysine methyltransferase DOT1L cofactor [Source:HGNC Symbol;Acc:HGNC:16063] | 32496 | -0.878 | -0.6069 | Yes |
| 102 | GFI1 | growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237] | 33342 | -1.122 | -0.6191 | Yes |
| 103 | GSG1 | germ cell associated 1 [Source:HGNC Symbol;Acc:HGNC:19716] | 33532 | -1.180 | -0.6130 | Yes |
| 104 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 33668 | -1.225 | -0.6051 | Yes |
| 105 | NOS1 | nitric oxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:7872] | 33709 | -1.238 | -0.5944 | Yes |
| 106 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 33887 | -1.300 | -0.5868 | Yes |
| 107 | MLF1 | myeloid leukemia factor 1 [Source:HGNC Symbol;Acc:HGNC:7125] | 33926 | -1.315 | -0.5754 | Yes |
| 108 | ZC3H14 | zinc finger CCCH-type containing 14 [Source:HGNC Symbol;Acc:HGNC:20509] | 34081 | -1.367 | -0.5665 | Yes |
| 109 | PARP2 | poly(ADP-ribose) polymerase 2 [Source:HGNC Symbol;Acc:HGNC:272] | 34123 | -1.384 | -0.5545 | Yes |
| 110 | PHF7 | PHD finger protein 7 [Source:HGNC Symbol;Acc:HGNC:18458] | 34564 | -1.568 | -0.5515 | Yes |
| 111 | IDE | insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381] | 34779 | -1.661 | -0.5415 | Yes |
| 112 | NF2 | neurofibromin 2 [Source:HGNC Symbol;Acc:HGNC:7773] | 34785 | -1.663 | -0.5258 | Yes |
| 113 | NPHP1 | nephrocystin 1 [Source:HGNC Symbol;Acc:HGNC:7905] | 35068 | -1.808 | -0.5163 | Yes |
| 114 | PRKAR2A | protein kinase cAMP-dependent type II regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9391] | 35069 | -1.808 | -0.4991 | Yes |
| 115 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 35120 | -1.833 | -0.4830 | Yes |
| 116 | IFT88 | intraflagellar transport 88 [Source:HGNC Symbol;Acc:HGNC:20606] | 35267 | -1.929 | -0.4687 | Yes |
| 117 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 35594 | -2.154 | -0.4570 | Yes |
| 118 | HSPA4L | heat shock protein family A (Hsp70) member 4 like [Source:HGNC Symbol;Acc:HGNC:17041] | 35672 | -2.214 | -0.4381 | Yes |
| 119 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35816 | -2.333 | -0.4198 | Yes |
| 120 | TNNI3 | troponin I3, cardiac type [Source:HGNC Symbol;Acc:HGNC:11947] | 35852 | -2.362 | -0.3983 | Yes |
| 121 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35861 | -2.370 | -0.3760 | Yes |
| 122 | PCSK4 | proprotein convertase subtilisin/kexin type 4 [Source:HGNC Symbol;Acc:HGNC:8746] | 36061 | -2.559 | -0.3571 | Yes |
| 123 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36079 | -2.583 | -0.3330 | Yes |
| 124 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 36108 | -2.616 | -0.3089 | Yes |
| 125 | HSPA2 | heat shock protein family A (Hsp70) member 2 [Source:HGNC Symbol;Acc:HGNC:5235] | 36143 | -2.659 | -0.2845 | Yes |
| 126 | STRBP | spermatid perinuclear RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16462] | 36157 | -2.673 | -0.2595 | Yes |
| 127 | TOPBP1 | DNA topoisomerase II binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17008] | 36239 | -2.758 | -0.2355 | Yes |
| 128 | GMCL1 | germ cell-less 1, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:23843] | 36272 | -2.786 | -0.2099 | Yes |
| 129 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36371 | -2.891 | -0.1850 | Yes |
| 130 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36630 | -3.207 | -0.1615 | Yes |
| 131 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36724 | -3.390 | -0.1319 | Yes |
| 132 | LPIN1 | lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345] | 36771 | -3.470 | -0.1001 | Yes |
| 133 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36868 | -3.675 | -0.0678 | Yes |
| 134 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36894 | -3.758 | -0.0328 | Yes |
| 135 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36971 | -4.005 | 0.0032 | Yes |
