Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN |
| Enrichment Score (ES) | 0.88430244 |
| Normalized Enrichment Score (NES) | 2.1309233 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.989 | 0.0246 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 1 | 4.939 | 0.0489 | Yes |
| 3 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 2 | 4.930 | 0.0732 | Yes |
| 4 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 3 | 4.921 | 0.0975 | Yes |
| 5 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 4 | 4.887 | 0.1215 | Yes |
| 6 | PHLDA1 | pleckstrin homology like domain family A member 1 [Source:HGNC Symbol;Acc:HGNC:8933] | 7 | 4.850 | 0.1454 | Yes |
| 7 | ACOD1 | aconitate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:33904] | 12 | 4.745 | 0.1687 | Yes |
| 8 | SOCS3 | suppressor of cytokine signaling 3 [Source:HGNC Symbol;Acc:HGNC:19391] | 13 | 4.740 | 0.1920 | Yes |
| 9 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 15 | 4.678 | 0.2150 | Yes |
| 10 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 16 | 4.622 | 0.2378 | Yes |
| 11 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 32 | 4.402 | 0.2591 | Yes |
| 12 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 41 | 4.239 | 0.2798 | Yes |
| 13 | ADORA2B | adenosine A2b receptor [Source:HGNC Symbol;Acc:HGNC:264] | 53 | 4.068 | 0.2995 | Yes |
| 14 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 54 | 4.052 | 0.3195 | Yes |
| 15 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 56 | 4.026 | 0.3393 | Yes |
| 16 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 61 | 3.985 | 0.3588 | Yes |
| 17 | ITGA5 | integrin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6141] | 69 | 3.808 | 0.3774 | Yes |
| 18 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 83 | 3.632 | 0.3950 | Yes |
| 19 | CD83 | CD83 molecule [Source:HGNC Symbol;Acc:HGNC:1703] | 87 | 3.611 | 0.4127 | Yes |
| 20 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 89 | 3.588 | 0.4303 | Yes |
| 21 | TRAF1 | TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031] | 91 | 3.572 | 0.4479 | Yes |
| 22 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 99 | 3.487 | 0.4649 | Yes |
| 23 | PDLIM7 | PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958] | 100 | 3.473 | 0.4820 | Yes |
| 24 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 102 | 3.437 | 0.4989 | Yes |
| 25 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 107 | 3.419 | 0.5156 | Yes |
| 26 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 116 | 3.363 | 0.5320 | Yes |
| 27 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 119 | 3.348 | 0.5484 | Yes |
| 28 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 121 | 3.338 | 0.5649 | Yes |
| 29 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 122 | 3.323 | 0.5812 | Yes |
| 30 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 148 | 3.174 | 0.5962 | Yes |
| 31 | ERRFI1 | ERBB receptor feedback inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:18185] | 156 | 3.125 | 0.6114 | Yes |
| 32 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 162 | 3.115 | 0.6266 | Yes |
| 33 | ACTG1 | actin gamma 1 [Source:HGNC Symbol;Acc:HGNC:144] | 185 | 2.984 | 0.6407 | Yes |
| 34 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 192 | 2.933 | 0.6550 | Yes |
| 35 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 211 | 2.870 | 0.6687 | Yes |
| 36 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 240 | 2.767 | 0.6816 | Yes |
| 37 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 263 | 2.685 | 0.6942 | Yes |
| 38 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 271 | 2.660 | 0.7071 | Yes |
| 39 | IL18RAP | interleukin 18 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5989] | 272 | 2.659 | 0.7202 | Yes |
| 40 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 281 | 2.632 | 0.7330 | Yes |
| 41 | IKBKE | inhibitor of nuclear factor kappa B kinase subunit epsilon [Source:HGNC Symbol;Acc:HGNC:14552] | 359 | 2.365 | 0.7425 | Yes |
| 42 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 385 | 2.291 | 0.7532 | Yes |
| 43 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 391 | 2.266 | 0.7642 | Yes |
| 44 | PIM1 | Pim-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8986] | 395 | 2.261 | 0.7752 | Yes |
| 45 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 443 | 2.174 | 0.7847 | Yes |
| 46 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 449 | 2.164 | 0.7952 | Yes |
| 47 | TAPBP | TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566] | 476 | 2.123 | 0.8050 | Yes |
| 48 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 484 | 2.110 | 0.8152 | Yes |
| 49 | HERPUD1 | homocysteine inducible ER protein with ubiquitin like domain 1 [Source:HGNC Symbol;Acc:HGNC:13744] | 528 | 2.037 | 0.8241 | Yes |
| 50 | PCDH7 | protocadherin 7 [Source:HGNC Symbol;Acc:HGNC:8659] | 546 | 2.004 | 0.8335 | Yes |
| 51 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 637 | 1.862 | 0.8402 | Yes |
| 52 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 639 | 1.859 | 0.8494 | Yes |
| 53 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 662 | 1.834 | 0.8578 | Yes |
| 54 | SRPRA | SRP receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:11307] | 687 | 1.815 | 0.8661 | Yes |
| 55 | RAC2 | Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802] | 733 | 1.743 | 0.8735 | Yes |
| 56 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 840 | 1.619 | 0.8786 | Yes |
| 57 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 911 | 1.546 | 0.8843 | Yes |
| 58 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 1575 | 1.130 | 0.8720 | No |
| 59 | BCL10 | BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989] | 3152 | 0.595 | 0.8323 | No |
| 60 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 3910 | 0.434 | 0.8140 | No |
| 61 | BCL2L11 | BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994] | 4431 | 0.339 | 0.8016 | No |
| 62 | RREB1 | ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449] | 5559 | 0.153 | 0.7719 | No |
| 63 | CDC42EP4 | CDC42 effector protein 4 [Source:HGNC Symbol;Acc:HGNC:17147] | 6051 | 0.086 | 0.7591 | No |
| 64 | UBB | ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463] | 6060 | 0.085 | 0.7593 | No |
| 65 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6626 | 0.000 | 0.7440 | No |
| 66 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 9054 | 0.000 | 0.6784 | No |
| 67 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13585 | 0.000 | 0.5560 | No |
| 68 | PLAUR | plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053] | 25940 | 0.000 | 0.2222 | No |
| 69 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27977 | -0.029 | 0.1674 | No |
| 70 | UBC | ubiquitin C [Source:HGNC Symbol;Acc:HGNC:12468] | 29063 | -0.182 | 0.1390 | No |
| 71 | VEGFA | vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680] | 30658 | -0.411 | 0.0979 | No |
| 72 | TSC22D1 | TSC22 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:16826] | 31816 | -0.600 | 0.0696 | No |
| 73 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 32767 | -0.816 | 0.0480 | No |
| 74 | PKM | pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] | 34036 | -1.195 | 0.0196 | No |
| 75 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141] | 34158 | -1.229 | 0.0224 | No |
| 76 | PHLDB1 | pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697] | 34635 | -1.404 | 0.0164 | No |
| 77 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 35081 | -1.617 | 0.0124 | No |
| 78 | RHOB | ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668] | 36189 | -2.355 | -0.0059 | No |
| 79 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36328 | -2.503 | 0.0027 | No |
| 80 | SCD | stearoyl-CoA desaturase [Source:HGNC Symbol;Acc:HGNC:10571] | 36918 | -3.629 | 0.0046 | No |
