Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | HECKER_IFNB1_TARGETS |
| Enrichment Score (ES) | 0.82499206 |
| Normalized Enrichment Score (NES) | 2.0608425 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 74 | 3.755 | 0.0404 | Yes |
| 2 | STAP1 | signal transducing adaptor family member 1 [Source:HGNC Symbol;Acc:HGNC:24133] | 101 | 3.461 | 0.0788 | Yes |
| 3 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 109 | 3.402 | 0.1170 | Yes |
| 4 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 114 | 3.371 | 0.1550 | Yes |
| 5 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 120 | 3.344 | 0.1926 | Yes |
| 6 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 134 | 3.225 | 0.2287 | Yes |
| 7 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 170 | 3.046 | 0.2621 | Yes |
| 8 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 191 | 2.942 | 0.2948 | Yes |
| 9 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 205 | 2.882 | 0.3270 | Yes |
| 10 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 206 | 2.882 | 0.3595 | Yes |
| 11 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 224 | 2.828 | 0.3910 | Yes |
| 12 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 238 | 2.774 | 0.4220 | Yes |
| 13 | DDX58 | DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102] | 239 | 2.772 | 0.4533 | Yes |
| 14 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 262 | 2.688 | 0.4830 | Yes |
| 15 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 270 | 2.660 | 0.5129 | Yes |
| 16 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 330 | 2.446 | 0.5389 | Yes |
| 17 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 372 | 2.318 | 0.5639 | Yes |
| 18 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 374 | 2.308 | 0.5900 | Yes |
| 19 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 454 | 2.149 | 0.6121 | Yes |
| 20 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 498 | 2.081 | 0.6344 | Yes |
| 21 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 625 | 1.882 | 0.6523 | Yes |
| 22 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 626 | 1.880 | 0.6735 | Yes |
| 23 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 635 | 1.863 | 0.6943 | Yes |
| 24 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 647 | 1.846 | 0.7149 | Yes |
| 25 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 818 | 1.639 | 0.7288 | Yes |
| 26 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 825 | 1.630 | 0.7470 | Yes |
| 27 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 857 | 1.602 | 0.7643 | Yes |
| 28 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 894 | 1.560 | 0.7809 | Yes |
| 29 | SH3BGRL2 | SH3 domain binding glutamate rich protein like 2 [Source:HGNC Symbol;Acc:HGNC:15567] | 1346 | 1.246 | 0.7828 | Yes |
| 30 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 1396 | 1.208 | 0.7951 | Yes |
| 31 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 1627 | 1.099 | 0.8013 | Yes |
| 32 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 1633 | 1.095 | 0.8135 | Yes |
| 33 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 1816 | 1.010 | 0.8200 | Yes |
| 34 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 2020 | 0.927 | 0.8250 | Yes |
| 35 | MYL9 | myosin light chain 9 [Source:HGNC Symbol;Acc:HGNC:15754] | 2793 | 0.684 | 0.8118 | No |
| 36 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 3036 | 0.622 | 0.8123 | No |
| 37 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 3633 | 0.487 | 0.8017 | No |
| 38 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 3759 | 0.460 | 0.8035 | No |
| 39 | SCO2 | synthesis of cytochrome C oxidase 2 [Source:HGNC Symbol;Acc:HGNC:10604] | 4117 | 0.396 | 0.7984 | No |
| 40 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4122 | 0.395 | 0.8027 | No |
| 41 | C1QB | complement C1q B chain [Source:HGNC Symbol;Acc:HGNC:1242] | 4132 | 0.393 | 0.8069 | No |
| 42 | DTX3L | deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323] | 4747 | 0.288 | 0.7936 | No |
| 43 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 5157 | 0.212 | 0.7849 | No |
| 44 | HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 [Source:HGNC Symbol;Acc:HGNC:24368] | 5546 | 0.153 | 0.7762 | No |
| 45 | RPS23 | ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:10410] | 6429 | 0.025 | 0.7526 | No |
| 46 | HES4 | hes family bHLH transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:24149] | 7419 | 0.000 | 0.7259 | No |
| 47 | ARG1 | arginase 1 [Source:HGNC Symbol;Acc:HGNC:663] | 7520 | 0.000 | 0.7232 | No |
| 48 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7955 | 0.000 | 0.7115 | No |
| 49 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9410 | 0.000 | 0.6722 | No |
| 50 | FCER1A | Fc fragment of IgE receptor Ia [Source:HGNC Symbol;Acc:HGNC:3609] | 10063 | 0.000 | 0.6545 | No |
| 51 | TYMP | thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148] | 10395 | 0.000 | 0.6456 | No |
| 52 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10681 | 0.000 | 0.6379 | No |
| 53 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12324 | 0.000 | 0.5935 | No |
| 54 | APOBEC3A | apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343] | 12616 | 0.000 | 0.5856 | No |
| 55 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12619 | 0.000 | 0.5856 | No |
| 56 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 13211 | 0.000 | 0.5696 | No |
| 57 | GP9 | glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444] | 17188 | 0.000 | 0.4621 | No |
| 58 | SERPING1 | serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228] | 17823 | 0.000 | 0.4450 | No |
| 59 | SPON2 | spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253] | 18982 | 0.000 | 0.4137 | No |
| 60 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19471 | 0.000 | 0.4005 | No |
| 61 | CHI3L1 | chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932] | 19869 | 0.000 | 0.3898 | No |
| 62 | C1QA | complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241] | 20144 | 0.000 | 0.3824 | No |
| 63 | C1QC | complement C1q C chain [Source:HGNC Symbol;Acc:HGNC:1245] | 20159 | 0.000 | 0.3820 | No |
| 64 | FFAR2 | free fatty acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:4501] | 20716 | 0.000 | 0.3670 | No |
| 65 | IFI6 | interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] | 20730 | 0.000 | 0.3666 | No |
| 66 | MMP25 | matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246] | 20912 | 0.000 | 0.3617 | No |
| 67 | CMTM5 | CKLF like MARVEL transmembrane domain containing 5 [Source:HGNC Symbol;Acc:HGNC:19176] | 22204 | 0.000 | 0.3268 | No |
| 68 | CMTM2 | CKLF like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19173] | 22217 | 0.000 | 0.3265 | No |
| 69 | TRBV27 | T cell receptor beta variable 27 [Source:HGNC Symbol;Acc:HGNC:12208] | 22819 | 0.000 | 0.3103 | No |
| 70 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 23062 | 0.000 | 0.3037 | No |
| 71 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 23262 | 0.000 | 0.2984 | No |
| 72 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 23455 | 0.000 | 0.2932 | No |
| 73 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 23875 | 0.000 | 0.2818 | No |
| 74 | KCNJ15 | potassium inwardly rectifying channel subfamily J member 15 [Source:HGNC Symbol;Acc:HGNC:6261] | 24083 | 0.000 | 0.2762 | No |
| 75 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 24162 | 0.000 | 0.2741 | No |
| 76 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24735 | 0.000 | 0.2587 | No |
| 77 | CABP5 | calcium binding protein 5 [Source:HGNC Symbol;Acc:HGNC:13714] | 24994 | 0.000 | 0.2517 | No |
| 78 | ZBP1 | Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176] | 26193 | 0.000 | 0.2193 | No |
| 79 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 26314 | 0.000 | 0.2161 | No |
| 80 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 27539 | 0.000 | 0.1830 | No |
| 81 | TREML1 | triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434] | 27969 | -0.029 | 0.1717 | No |
| 82 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 27986 | -0.029 | 0.1716 | No |
| 83 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 27996 | -0.030 | 0.1717 | No |
| 84 | JUP | junction plakoglobin [Source:HGNC Symbol;Acc:HGNC:6207] | 29592 | -0.256 | 0.1315 | No |
| 85 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 29778 | -0.287 | 0.1297 | No |
| 86 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 29811 | -0.291 | 0.1322 | No |
| 87 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 30371 | -0.365 | 0.1212 | No |
| 88 | CYP4F3 | cytochrome P450 family 4 subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:2646] | 32168 | -0.675 | 0.0803 | No |
| 89 | ITGA2B | integrin subunit alpha 2b [Source:HGNC Symbol;Acc:HGNC:6138] | 32876 | -0.841 | 0.0706 | No |
| 90 | PROS1 | protein S [Source:HGNC Symbol;Acc:HGNC:9456] | 33512 | -1.023 | 0.0650 | No |
| 91 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 33799 | -1.111 | 0.0699 | No |
| 92 | MGAM | maltase-glucoamylase [Source:HGNC Symbol;Acc:HGNC:7043] | 35224 | -1.688 | 0.0504 | No |
