Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | ISHIDA_E2F_TARGETS |
| Enrichment Score (ES) | -0.87196624 |
| Normalized Enrichment Score (NES) | -1.7186756 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0010339395 |
| FWER p-Value | 0.009 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 4412 | 0.341 | -0.1154 | No |
| 2 | ANXA8L1 | annexin A8 like 1 [Source:HGNC Symbol;Acc:HGNC:23334] | 22252 | 0.000 | -0.5970 | No |
| 3 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27912 | -0.021 | -0.7496 | No |
| 4 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 28646 | -0.123 | -0.7680 | No |
| 5 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30070 | -0.326 | -0.8029 | No |
| 6 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 30452 | -0.375 | -0.8091 | No |
| 7 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 31457 | -0.537 | -0.8303 | No |
| 8 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 32085 | -0.659 | -0.8401 | No |
| 9 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33267 | -0.949 | -0.8616 | Yes |
| 10 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33479 | -1.012 | -0.8563 | Yes |
| 11 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 33663 | -1.069 | -0.8496 | Yes |
| 12 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33690 | -1.077 | -0.8386 | Yes |
| 13 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33721 | -1.084 | -0.8276 | Yes |
| 14 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 33877 | -1.138 | -0.8194 | Yes |
| 15 | CDT1 | chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576] | 34470 | -1.342 | -0.8207 | Yes |
| 16 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34522 | -1.361 | -0.8073 | Yes |
| 17 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34533 | -1.364 | -0.7927 | Yes |
| 18 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 34584 | -1.386 | -0.7790 | Yes |
| 19 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 34637 | -1.405 | -0.7651 | Yes |
| 20 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 34826 | -1.475 | -0.7541 | Yes |
| 21 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35270 | -1.715 | -0.7473 | Yes |
| 22 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35303 | -1.732 | -0.7293 | Yes |
| 23 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35417 | -1.787 | -0.7129 | Yes |
| 24 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35455 | -1.811 | -0.6942 | Yes |
| 25 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35493 | -1.831 | -0.6753 | Yes |
| 26 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35508 | -1.842 | -0.6556 | Yes |
| 27 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35527 | -1.854 | -0.6359 | Yes |
| 28 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35732 | -2.004 | -0.6196 | Yes |
| 29 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35736 | -2.006 | -0.5978 | Yes |
| 30 | LBR | lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518] | 35876 | -2.113 | -0.5785 | Yes |
| 31 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 35886 | -2.120 | -0.5557 | Yes |
| 32 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35935 | -2.155 | -0.5335 | Yes |
| 33 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.5104 | Yes |
| 34 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36062 | -2.250 | -0.4886 | Yes |
| 35 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.4645 | Yes |
| 36 | ANLN | anillin actin binding protein [Source:HGNC Symbol;Acc:HGNC:14082] | 36095 | -2.274 | -0.4400 | Yes |
| 37 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36099 | -2.278 | -0.4153 | Yes |
| 38 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36191 | -2.357 | -0.3921 | Yes |
| 39 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36232 | -2.394 | -0.3671 | Yes |
| 40 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36249 | -2.411 | -0.3413 | Yes |
| 41 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36284 | -2.451 | -0.3155 | Yes |
| 42 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36286 | -2.451 | -0.2888 | Yes |
| 43 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36546 | -2.789 | -0.2655 | Yes |
| 44 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36555 | -2.800 | -0.2352 | Yes |
| 45 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36622 | -2.908 | -0.2053 | Yes |
| 46 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36627 | -2.912 | -0.1737 | Yes |
| 47 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36629 | -2.914 | -0.1420 | Yes |
| 48 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36679 | -3.000 | -0.1106 | Yes |
| 49 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36789 | -3.243 | -0.0782 | Yes |
| 50 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36945 | -3.773 | -0.0413 | Yes |
| 51 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37029 | -4.153 | 0.0016 | Yes |
