Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | LEE_EARLY_T_LYMPHOCYTE_UP |
| Enrichment Score (ES) | -0.8212082 |
| Normalized Enrichment Score (NES) | -1.7322195 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.7289516E-4 |
| FWER p-Value | 0.003 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RAPGEF5 | Rap guanine nucleotide exchange factor 5 [Source:HGNC Symbol;Acc:HGNC:16862] | 1084 | 1.407 | -0.0203 | No |
| 2 | SYK | spleen associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11491] | 1194 | 1.334 | -0.0146 | No |
| 3 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1504 | 1.154 | -0.0156 | No |
| 4 | CENPW | centromere protein W [Source:HGNC Symbol;Acc:HGNC:21488] | 1757 | 1.033 | -0.0157 | No |
| 5 | AEBP1 | AE binding protein 1 [Source:HGNC Symbol;Acc:HGNC:303] | 1969 | 0.950 | -0.0153 | No |
| 6 | SLC1A4 | solute carrier family 1 member 4 [Source:HGNC Symbol;Acc:HGNC:10942] | 2585 | 0.737 | -0.0272 | No |
| 7 | GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4129] | 3126 | 0.602 | -0.0380 | No |
| 8 | CDC25A | cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725] | 3222 | 0.578 | -0.0368 | No |
| 9 | GNA15 | G protein subunit alpha 15 [Source:HGNC Symbol;Acc:HGNC:4383] | 3435 | 0.527 | -0.0392 | No |
| 10 | LDLRAD4 | low density lipoprotein receptor class A domain containing 4 [Source:HGNC Symbol;Acc:HGNC:1224] | 3437 | 0.527 | -0.0358 | No |
| 11 | PON1 | paraoxonase 1 [Source:HGNC Symbol;Acc:HGNC:9204] | 4016 | 0.412 | -0.0488 | No |
| 12 | PALLD | palladin, cytoskeletal associated protein [Source:HGNC Symbol;Acc:HGNC:17068] | 4846 | 0.269 | -0.0695 | No |
| 13 | FAIM | Fas apoptotic inhibitory molecule [Source:HGNC Symbol;Acc:HGNC:18703] | 5818 | 0.121 | -0.0949 | No |
| 14 | MIR646HG | MIR646 host gene [Source:HGNC Symbol;Acc:HGNC:27659] | 8258 | 0.000 | -0.1609 | No |
| 15 | HHIP | hedgehog interacting protein [Source:HGNC Symbol;Acc:HGNC:14866] | 8333 | 0.000 | -0.1629 | No |
| 16 | TNFRSF21 | TNF receptor superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:13469] | 9451 | 0.000 | -0.1931 | No |
| 17 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12665 | 0.000 | -0.2800 | No |
| 18 | SCRN1 | secernin 1 [Source:HGNC Symbol;Acc:HGNC:22192] | 14231 | 0.000 | -0.3223 | No |
| 19 | MZB1 | marginal zone B and B1 cell specific protein [Source:HGNC Symbol;Acc:HGNC:30125] | 14833 | 0.000 | -0.3385 | No |
| 20 | ARPP21 | cAMP regulated phosphoprotein 21 [Source:HGNC Symbol;Acc:HGNC:16968] | 21032 | 0.000 | -0.5061 | No |
| 21 | TSHR | thyroid stimulating hormone receptor [Source:HGNC Symbol;Acc:HGNC:12373] | 22208 | 0.000 | -0.5379 | No |
| 22 | FAM72C | family with sequence similarity 72 member C [Source:HGNC Symbol;Acc:HGNC:30602] | 22499 | 0.000 | -0.5457 | No |
| 23 | CD1E | CD1e molecule [Source:HGNC Symbol;Acc:HGNC:1638] | 23120 | 0.000 | -0.5625 | No |
| 24 | CD1B | CD1b molecule [Source:HGNC Symbol;Acc:HGNC:1635] | 23123 | 0.000 | -0.5626 | No |
| 25 | CD1A | CD1a molecule [Source:HGNC Symbol;Acc:HGNC:1634] | 23124 | 0.000 | -0.5626 | No |
| 26 | CD99 | CD99 molecule (Xg blood group) [Source:HGNC Symbol;Acc:HGNC:7082] | 23261 | 0.000 | -0.5662 | No |
| 27 | CPVL | carboxypeptidase vitellogenic like [Source:HGNC Symbol;Acc:HGNC:14399] | 23945 | 0.000 | -0.5847 | No |
| 28 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 24301 | 0.000 | -0.5943 | No |
| 29 | NLGN4X | neuroligin 4 X-linked [Source:HGNC Symbol;Acc:HGNC:14287] | 25754 | 0.000 | -0.6336 | No |
| 30 | PALM2AKAP2 | PALM2 and AKAP2 fusion [Source:HGNC Symbol;Acc:HGNC:33529] | 27775 | -0.000 | -0.6882 | No |
| 31 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 27831 | -0.006 | -0.6896 | No |
| 32 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27912 | -0.021 | -0.6917 | No |
| 33 | GSE1 | Gse1 coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:28979] | 27992 | -0.029 | -0.6936 | No |
| 34 | GFI1 | growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237] | 28114 | -0.049 | -0.6966 | No |
| 35 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 28646 | -0.123 | -0.7101 | No |
| 36 | MYB | MYB proto-oncogene, transcription factor [Source:HGNC Symbol;Acc:HGNC:7545] | 28989 | -0.170 | -0.7183 | No |
| 37 | GGH | gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] | 29206 | -0.201 | -0.7228 | No |
| 38 | DNTT | DNA nucleotidylexotransferase [Source:HGNC Symbol;Acc:HGNC:2983] | 29469 | -0.240 | -0.7284 | No |
| 39 | TMSB15A | thymosin beta 15a [Source:HGNC Symbol;Acc:HGNC:30744] | 30211 | -0.343 | -0.7462 | No |
| 40 | CRNDE | colorectal neoplasia differentially expressed [Source:HGNC Symbol;Acc:HGNC:37078] | 30993 | -0.461 | -0.7644 | No |
| 41 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31056 | -0.470 | -0.7630 | No |
| 42 | LETM1 | leucine zipper and EF-hand containing transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:6556] | 31097 | -0.476 | -0.7610 | No |
| 43 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 31158 | -0.486 | -0.7595 | No |
| 44 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 32214 | -0.686 | -0.7836 | No |
| 45 | RCAN1 | regulator of calcineurin 1 [Source:HGNC Symbol;Acc:HGNC:3040] | 32362 | -0.712 | -0.7830 | No |
| 46 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 32625 | -0.776 | -0.7851 | No |
| 47 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32700 | -0.796 | -0.7820 | No |
| 48 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33479 | -1.012 | -0.7965 | No |
| 49 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 33771 | -1.101 | -0.7973 | No |
| 50 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34655 | -1.411 | -0.8121 | Yes |
| 51 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34665 | -1.416 | -0.8033 | Yes |
| 52 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 34826 | -1.475 | -0.7981 | Yes |
| 53 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 34894 | -1.508 | -0.7902 | Yes |
| 54 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 34952 | -1.544 | -0.7818 | Yes |
| 55 | DIAPH3 | diaphanous related formin 3 [Source:HGNC Symbol;Acc:HGNC:15480] | 34999 | -1.564 | -0.7730 | Yes |
| 56 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35012 | -1.573 | -0.7632 | Yes |
| 57 | DSCC1 | DNA replication and sister chromatid cohesion 1 [Source:HGNC Symbol;Acc:HGNC:24453] | 35083 | -1.617 | -0.7547 | Yes |
| 58 | RUFY3 | RUN and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30285] | 35302 | -1.732 | -0.7495 | Yes |
| 59 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35315 | -1.737 | -0.7387 | Yes |
| 60 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35527 | -1.854 | -0.7324 | Yes |
| 61 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35530 | -1.855 | -0.7206 | Yes |
| 62 | E2F7 | E2F transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:23820] | 35545 | -1.864 | -0.7090 | Yes |
| 63 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 35626 | -1.922 | -0.6988 | Yes |
| 64 | CDCA2 | cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623] | 35638 | -1.929 | -0.6867 | Yes |
| 65 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35645 | -1.933 | -0.6744 | Yes |
| 66 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35659 | -1.943 | -0.6623 | Yes |
| 67 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35723 | -1.996 | -0.6511 | Yes |
| 68 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35736 | -2.006 | -0.6386 | Yes |
| 69 | LRR1 | leucine rich repeat protein 1 [Source:HGNC Symbol;Acc:HGNC:19742] | 35751 | -2.018 | -0.6260 | Yes |
| 70 | CENPU | centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348] | 35816 | -2.070 | -0.6144 | Yes |
| 71 | MPP1 | membrane palmitoylated protein 1 [Source:HGNC Symbol;Acc:HGNC:7219] | 35864 | -2.106 | -0.6021 | Yes |
| 72 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35889 | -2.122 | -0.5891 | Yes |
| 73 | UHRF1 | ubiquitin like with PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:12556] | 35897 | -2.126 | -0.5756 | Yes |
| 74 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35912 | -2.142 | -0.5622 | Yes |
| 75 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35930 | -2.153 | -0.5489 | Yes |
| 76 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35935 | -2.155 | -0.5351 | Yes |
| 77 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.5217 | Yes |
| 78 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35968 | -2.186 | -0.5079 | Yes |
| 79 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36024 | -2.225 | -0.4951 | Yes |
| 80 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 36040 | -2.235 | -0.4811 | Yes |
| 81 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.4676 | Yes |
| 82 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36099 | -2.278 | -0.4534 | Yes |
| 83 | KNL1 | kinetochore scaffold 1 [Source:HGNC Symbol;Acc:HGNC:24054] | 36145 | -2.317 | -0.4398 | Yes |
| 84 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36238 | -2.399 | -0.4268 | Yes |
| 85 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36249 | -2.411 | -0.4116 | Yes |
| 86 | KIF15 | kinesin family member 15 [Source:HGNC Symbol;Acc:HGNC:17273] | 36265 | -2.434 | -0.3964 | Yes |
| 87 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36289 | -2.458 | -0.3812 | Yes |
| 88 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36304 | -2.474 | -0.3657 | Yes |
| 89 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 36311 | -2.482 | -0.3499 | Yes |
| 90 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36360 | -2.539 | -0.3348 | Yes |
| 91 | CEP128 | centrosomal protein 128 [Source:HGNC Symbol;Acc:HGNC:20359] | 36375 | -2.556 | -0.3188 | Yes |
| 92 | ATAD2 | ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123] | 36387 | -2.570 | -0.3025 | Yes |
| 93 | CEP55 | centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161] | 36433 | -2.620 | -0.2869 | Yes |
| 94 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36458 | -2.656 | -0.2705 | Yes |
| 95 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 36505 | -2.720 | -0.2543 | Yes |
| 96 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36555 | -2.800 | -0.2376 | Yes |
| 97 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36562 | -2.813 | -0.2197 | Yes |
| 98 | CXXC5 | CXXC finger protein 5 [Source:HGNC Symbol;Acc:HGNC:26943] | 36564 | -2.819 | -0.2016 | Yes |
| 99 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 36573 | -2.835 | -0.1836 | Yes |
| 100 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36620 | -2.903 | -0.1661 | Yes |
| 101 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36622 | -2.908 | -0.1475 | Yes |
| 102 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36679 | -3.000 | -0.1297 | Yes |
| 103 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36747 | -3.148 | -0.1113 | Yes |
| 104 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 36858 | -3.461 | -0.0920 | Yes |
| 105 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36872 | -3.490 | -0.0699 | Yes |
| 106 | NEIL3 | nei like DNA glycosylase 3 [Source:HGNC Symbol;Acc:HGNC:24573] | 36921 | -3.644 | -0.0478 | Yes |
| 107 | E2F2 | E2F transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:3114] | 36937 | -3.731 | -0.0242 | Yes |
| 108 | TFDP2 | transcription factor Dp-2 [Source:HGNC Symbol;Acc:HGNC:11751] | 37064 | -4.399 | 0.0007 | Yes |
