Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | LIANG_SILENCED_BY_METHYLATION_2 |
| Enrichment Score (ES) | 0.817464 |
| Normalized Enrichment Score (NES) | 1.921207 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0021892146 |
| FWER p-Value | 0.016 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 1 | 4.939 | 0.0945 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 4 | 4.887 | 0.1880 | Yes |
| 3 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 11 | 4.782 | 0.2793 | Yes |
| 4 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 134 | 3.225 | 0.3378 | Yes |
| 5 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 169 | 3.064 | 0.3955 | Yes |
| 6 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 205 | 2.882 | 0.4497 | Yes |
| 7 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 223 | 2.834 | 0.5035 | Yes |
| 8 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 240 | 2.767 | 0.5561 | Yes |
| 9 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 262 | 2.688 | 0.6069 | Yes |
| 10 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 330 | 2.446 | 0.6519 | Yes |
| 11 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 454 | 2.149 | 0.6897 | Yes |
| 12 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 635 | 1.863 | 0.7205 | Yes |
| 13 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 647 | 1.846 | 0.7556 | Yes |
| 14 | SERPINB2 | serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584] | 1091 | 1.400 | 0.7704 | Yes |
| 15 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 1396 | 1.208 | 0.7853 | Yes |
| 16 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 1633 | 1.095 | 0.7999 | Yes |
| 17 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 1728 | 1.050 | 0.8175 | Yes |
| 18 | UCHL1 | ubiquitin C-terminal hydrolase L1 [Source:HGNC Symbol;Acc:HGNC:12513] | 3487 | 0.517 | 0.7799 | No |
| 19 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 3563 | 0.500 | 0.7874 | No |
| 20 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 4000 | 0.415 | 0.7836 | No |
| 21 | HBEGF | heparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059] | 4474 | 0.332 | 0.7772 | No |
| 22 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 5157 | 0.212 | 0.7628 | No |
| 23 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 5380 | 0.179 | 0.7602 | No |
| 24 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 5814 | 0.121 | 0.7509 | No |
| 25 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 6488 | 0.014 | 0.7330 | No |
| 26 | AREG | amphiregulin [Source:HGNC Symbol;Acc:HGNC:651] | 7513 | 0.000 | 0.7053 | No |
| 27 | SLPI | secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092] | 9495 | 0.000 | 0.6518 | No |
| 28 | LCN2 | lipocalin 2 [Source:HGNC Symbol;Acc:HGNC:6526] | 11089 | 0.000 | 0.6088 | No |
| 29 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12578 | 0.000 | 0.5686 | No |
| 30 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 12826 | 0.000 | 0.5620 | No |
| 31 | BIK | BCL2 interacting killer [Source:HGNC Symbol;Acc:HGNC:1051] | 15639 | 0.000 | 0.4860 | No |
| 32 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17187 | 0.000 | 0.4443 | No |
| 33 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18291 | 0.000 | 0.4145 | No |
| 34 | GAGE1 | G antigen 1 [Source:HGNC Symbol;Acc:HGNC:4098] | 18822 | 0.000 | 0.4002 | No |
| 35 | MMP1 | matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155] | 19129 | 0.000 | 0.3919 | No |
| 36 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19466 | 0.000 | 0.3828 | No |
| 37 | DHRS2 | dehydrogenase/reductase 2 [Source:HGNC Symbol;Acc:HGNC:18349] | 20002 | 0.000 | 0.3684 | No |
| 38 | PI3 | peptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:8947] | 20030 | 0.000 | 0.3676 | No |
| 39 | IFI6 | interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] | 20730 | 0.000 | 0.3488 | No |
| 40 | H2AC18 | H2A clustered histone 18 [Source:HGNC Symbol;Acc:HGNC:4736] | 21839 | 0.000 | 0.3189 | No |
| 41 | KRT17 | keratin 17 [Source:HGNC Symbol;Acc:HGNC:6427] | 22112 | 0.000 | 0.3115 | No |
| 42 | CTAG1B | cancer/testis antigen 1B [Source:HGNC Symbol;Acc:HGNC:2491] | 22508 | 0.000 | 0.3008 | No |
| 43 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 23875 | 0.000 | 0.2640 | No |
| 44 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 24724 | 0.000 | 0.2411 | No |
| 45 | NT5E | 5'-nucleotidase ecto [Source:HGNC Symbol;Acc:HGNC:8021] | 24934 | 0.000 | 0.2354 | No |
| 46 | MAGEA12 | MAGE family member A12 [Source:HGNC Symbol;Acc:HGNC:6799] | 26794 | 0.000 | 0.1852 | No |
| 47 | MAGEA2 | MAGE family member A2 [Source:HGNC Symbol;Acc:HGNC:6800] | 26948 | 0.000 | 0.1811 | No |
| 48 | MAGEA3 | MAGE family member A3 [Source:HGNC Symbol;Acc:HGNC:6801] | 26953 | 0.000 | 0.1810 | No |
| 49 | MAGEA4 | MAGE family member A4 [Source:HGNC Symbol;Acc:HGNC:6802] | 26955 | 0.000 | 0.1809 | No |
| 50 | SSX2 | SSX family member 2 [Source:HGNC Symbol;Acc:HGNC:11336] | 27462 | 0.000 | 0.1673 | No |
| 51 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 27539 | 0.000 | 0.1652 | No |
| 52 | STC1 | stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373] | 27657 | 0.000 | 0.1621 | No |
| 53 | SP100 | SP100 nuclear antigen [Source:HGNC Symbol;Acc:HGNC:11206] | 28371 | -0.086 | 0.1445 | No |
| 54 | STX3 | syntaxin 3 [Source:HGNC Symbol;Acc:HGNC:11438] | 29576 | -0.253 | 0.1168 | No |
| 55 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 30805 | -0.432 | 0.0919 | No |
| 56 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 31480 | -0.541 | 0.0841 | No |
| 57 | H2AC6 | H2A clustered histone 6 [Source:HGNC Symbol;Acc:HGNC:4733] | 33978 | -1.178 | 0.0392 | No |
| 58 | H2BC6 | H2B clustered histone 6 [Source:HGNC Symbol;Acc:HGNC:4753] | 36164 | -2.341 | 0.0250 | No |
