Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | MORI_IMMATURE_B_LYMPHOCYTE_DN |
| Enrichment Score (ES) | -0.8095299 |
| Normalized Enrichment Score (NES) | -1.6983801 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0016585741 |
| FWER p-Value | 0.021 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1742 | 1.042 | -0.0392 | No |
| 2 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 1909 | 0.973 | -0.0363 | No |
| 3 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2049 | 0.918 | -0.0332 | No |
| 4 | PREP | prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358] | 3583 | 0.496 | -0.0709 | No |
| 5 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 3722 | 0.467 | -0.0711 | No |
| 6 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] | 4439 | 0.337 | -0.0879 | No |
| 7 | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100] | 5289 | 0.194 | -0.1093 | No |
| 8 | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [Source:HGNC Symbol;Acc:HGNC:11101] | 5855 | 0.113 | -0.1238 | No |
| 9 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 6025 | 0.087 | -0.1277 | No |
| 10 | HAUS3 | HAUS augmin like complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28719] | 6084 | 0.083 | -0.1286 | No |
| 11 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12665 | 0.000 | -0.3064 | No |
| 12 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16775 | 0.000 | -0.4175 | No |
| 13 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18477 | 0.000 | -0.4635 | No |
| 14 | RAMP1 | receptor activity modifying protein 1 [Source:HGNC Symbol;Acc:HGNC:9843] | 20365 | 0.000 | -0.5145 | No |
| 15 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 24301 | 0.000 | -0.6208 | No |
| 16 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27912 | -0.021 | -0.7182 | No |
| 17 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 28082 | -0.044 | -0.7225 | No |
| 18 | SLC16A1 | solute carrier family 16 member 1 [Source:HGNC Symbol;Acc:HGNC:10922] | 28501 | -0.103 | -0.7330 | No |
| 19 | CBX1 | chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551] | 28853 | -0.150 | -0.7413 | No |
| 20 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 28974 | -0.167 | -0.7433 | No |
| 21 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30070 | -0.326 | -0.7704 | No |
| 22 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 30352 | -0.363 | -0.7753 | No |
| 23 | ACTN4 | actinin alpha 4 [Source:HGNC Symbol;Acc:HGNC:166] | 30879 | -0.446 | -0.7861 | No |
| 24 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31056 | -0.470 | -0.7874 | No |
| 25 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 31121 | -0.480 | -0.7855 | No |
| 26 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 31158 | -0.486 | -0.7828 | No |
| 27 | UCK2 | uridine-cytidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12562] | 31199 | -0.495 | -0.7801 | No |
| 28 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31269 | -0.505 | -0.7782 | No |
| 29 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 31772 | -0.593 | -0.7872 | No |
| 30 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 32085 | -0.659 | -0.7907 | No |
| 31 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 32783 | -0.819 | -0.8033 | Yes |
| 32 | HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:HGNC:24941] | 32819 | -0.827 | -0.7980 | Yes |
| 33 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 32854 | -0.836 | -0.7926 | Yes |
| 34 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33267 | -0.949 | -0.7966 | Yes |
| 35 | XRCC6 | X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055] | 33316 | -0.961 | -0.7906 | Yes |
| 36 | RBBP4 | RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887] | 33360 | -0.974 | -0.7844 | Yes |
| 37 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33479 | -1.012 | -0.7800 | Yes |
| 38 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33721 | -1.084 | -0.7783 | Yes |
| 39 | CENPL | centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879] | 33808 | -1.114 | -0.7722 | Yes |
| 40 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 33838 | -1.126 | -0.7645 | Yes |
| 41 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 33972 | -1.176 | -0.7592 | Yes |
| 42 | TUBA1B | tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809] | 34314 | -1.283 | -0.7587 | Yes |
| 43 | CKAP5 | cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:HGNC:28959] | 34435 | -1.328 | -0.7519 | Yes |
| 44 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34522 | -1.361 | -0.7440 | Yes |
| 45 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34533 | -1.364 | -0.7339 | Yes |
| 46 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 34562 | -1.376 | -0.7243 | Yes |
| 47 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 34637 | -1.405 | -0.7157 | Yes |
| 48 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 34894 | -1.508 | -0.7112 | Yes |
| 49 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34896 | -1.510 | -0.6998 | Yes |
| 50 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 34899 | -1.514 | -0.6884 | Yes |
| 51 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 34905 | -1.518 | -0.6771 | Yes |
| 52 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 35304 | -1.732 | -0.6748 | Yes |
| 53 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35315 | -1.737 | -0.6619 | Yes |
| 54 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35417 | -1.787 | -0.6512 | Yes |
| 55 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35455 | -1.811 | -0.6385 | Yes |
| 56 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35493 | -1.831 | -0.6256 | Yes |
| 57 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35508 | -1.842 | -0.6121 | Yes |
| 58 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35527 | -1.854 | -0.5986 | Yes |
| 59 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35659 | -1.943 | -0.5874 | Yes |
| 60 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35732 | -2.004 | -0.5743 | Yes |
| 61 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 35882 | -2.115 | -0.5623 | Yes |
| 62 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35912 | -2.142 | -0.5469 | Yes |
| 63 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35935 | -2.155 | -0.5312 | Yes |
| 64 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.5154 | Yes |
| 65 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35963 | -2.182 | -0.4989 | Yes |
| 66 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35968 | -2.186 | -0.4825 | Yes |
| 67 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36012 | -2.211 | -0.4670 | Yes |
| 68 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 36040 | -2.235 | -0.4509 | Yes |
| 69 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36062 | -2.250 | -0.4344 | Yes |
| 70 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 36078 | -2.261 | -0.4177 | Yes |
| 71 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.4007 | Yes |
| 72 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36099 | -2.278 | -0.3840 | Yes |
| 73 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36191 | -2.357 | -0.3686 | Yes |
| 74 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36232 | -2.394 | -0.3516 | Yes |
| 75 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36289 | -2.458 | -0.3345 | Yes |
| 76 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36304 | -2.474 | -0.3162 | Yes |
| 77 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36380 | -2.561 | -0.2989 | Yes |
| 78 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36470 | -2.674 | -0.2811 | Yes |
| 79 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36546 | -2.789 | -0.2621 | Yes |
| 80 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36555 | -2.800 | -0.2411 | Yes |
| 81 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36562 | -2.813 | -0.2201 | Yes |
| 82 | PTGR1 | prostaglandin reductase 1 [Source:HGNC Symbol;Acc:HGNC:18429] | 36600 | -2.879 | -0.1993 | Yes |
| 83 | GSN | gelsolin [Source:HGNC Symbol;Acc:HGNC:4620] | 36609 | -2.892 | -0.1777 | Yes |
| 84 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36620 | -2.903 | -0.1560 | Yes |
| 85 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36622 | -2.908 | -0.1341 | Yes |
| 86 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36627 | -2.912 | -0.1122 | Yes |
| 87 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36629 | -2.914 | -0.0902 | Yes |
| 88 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36679 | -3.000 | -0.0689 | Yes |
| 89 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36757 | -3.180 | -0.0469 | Yes |
| 90 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36872 | -3.490 | -0.0236 | Yes |
| 91 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36988 | -3.904 | 0.0028 | Yes |
