Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.91741735 |
| Normalized Enrichment Score (NES) | 2.257782 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 1 | 4.939 | 0.0283 | Yes |
| 2 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 3 | 4.921 | 0.0564 | Yes |
| 3 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 17 | 4.615 | 0.0825 | Yes |
| 4 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 35 | 4.335 | 0.1069 | Yes |
| 5 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 39 | 4.269 | 0.1313 | Yes |
| 6 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 41 | 4.239 | 0.1556 | Yes |
| 7 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 54 | 4.052 | 0.1785 | Yes |
| 8 | BCL2L1 | BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992] | 58 | 4.007 | 0.2013 | Yes |
| 9 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 61 | 3.985 | 0.2241 | Yes |
| 10 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 74 | 3.755 | 0.2453 | Yes |
| 11 | RGS16 | regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997] | 79 | 3.667 | 0.2662 | Yes |
| 12 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 83 | 3.632 | 0.2869 | Yes |
| 13 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 89 | 3.588 | 0.3074 | Yes |
| 14 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 99 | 3.487 | 0.3271 | Yes |
| 15 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 102 | 3.437 | 0.3467 | Yes |
| 16 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 107 | 3.419 | 0.3662 | Yes |
| 17 | RHOC | ras homolog family member C [Source:HGNC Symbol;Acc:HGNC:669] | 111 | 3.385 | 0.3855 | Yes |
| 18 | GK | glycerol kinase [Source:HGNC Symbol;Acc:HGNC:4289] | 112 | 3.381 | 0.4049 | Yes |
| 19 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 121 | 3.338 | 0.4238 | Yes |
| 20 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 122 | 3.323 | 0.4429 | Yes |
| 21 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 123 | 3.321 | 0.4619 | Yes |
| 22 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 148 | 3.174 | 0.4794 | Yes |
| 23 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 162 | 3.115 | 0.4969 | Yes |
| 24 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 181 | 2.996 | 0.5136 | Yes |
| 25 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 192 | 2.933 | 0.5302 | Yes |
| 26 | MSR1 | macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376] | 213 | 2.857 | 0.5460 | Yes |
| 27 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 236 | 2.780 | 0.5613 | Yes |
| 28 | IL1RL1 | interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998] | 241 | 2.756 | 0.5770 | Yes |
| 29 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 281 | 2.632 | 0.5910 | Yes |
| 30 | STK10 | serine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388] | 301 | 2.553 | 0.6052 | Yes |
| 31 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 314 | 2.499 | 0.6191 | Yes |
| 32 | ACSL4 | acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] | 375 | 2.305 | 0.6307 | Yes |
| 33 | PNP | purine nucleoside phosphorylase [Source:HGNC Symbol;Acc:HGNC:7892] | 377 | 2.304 | 0.6439 | Yes |
| 34 | TGFB1 | transforming growth factor beta 1 [Source:HGNC Symbol;Acc:HGNC:11766] | 402 | 2.254 | 0.6562 | Yes |
| 35 | LCP2 | lymphocyte cytosolic protein 2 [Source:HGNC Symbol;Acc:HGNC:6529] | 424 | 2.223 | 0.6683 | Yes |
| 36 | CFLAR | CASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876] | 437 | 2.182 | 0.6805 | Yes |
| 37 | MYO10 | myosin X [Source:HGNC Symbol;Acc:HGNC:7593] | 446 | 2.169 | 0.6927 | Yes |
| 38 | IFRD1 | interferon related developmental regulator 1 [Source:HGNC Symbol;Acc:HGNC:5456] | 453 | 2.152 | 0.7049 | Yes |
| 39 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 454 | 2.149 | 0.7172 | Yes |
| 40 | ADAR | adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225] | 458 | 2.142 | 0.7294 | Yes |
| 41 | APBB1IP | amyloid beta precursor protein binding family B member 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:17379] | 480 | 2.112 | 0.7409 | Yes |
| 42 | HCLS1 | hematopoietic cell-specific Lyn substrate 1 [Source:HGNC Symbol;Acc:HGNC:4844] | 482 | 2.111 | 0.7530 | Yes |
| 43 | DEGS1 | delta 4-desaturase, sphingolipid 1 [Source:HGNC Symbol;Acc:HGNC:13709] | 487 | 2.105 | 0.7650 | Yes |
| 44 | SLC20A1 | solute carrier family 20 member 1 [Source:HGNC Symbol;Acc:HGNC:10946] | 497 | 2.084 | 0.7767 | Yes |
| 45 | CLEC4D | C-type lectin domain family 4 member D [Source:HGNC Symbol;Acc:HGNC:14554] | 558 | 1.981 | 0.7864 | Yes |
| 46 | CLN3 | CLN3 lysosomal/endosomal transmembrane protein, battenin [Source:HGNC Symbol;Acc:HGNC:2074] | 569 | 1.964 | 0.7974 | Yes |
| 47 | SRGN | serglycin [Source:HGNC Symbol;Acc:HGNC:9361] | 602 | 1.920 | 0.8075 | Yes |
| 48 | ETF1 | eukaryotic translation termination factor 1 [Source:HGNC Symbol;Acc:HGNC:3477] | 603 | 1.915 | 0.8185 | Yes |
| 49 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 637 | 1.862 | 0.8283 | Yes |
| 50 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 639 | 1.859 | 0.8389 | Yes |
| 51 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 677 | 1.824 | 0.8483 | Yes |
| 52 | RNF11 | ring finger protein 11 [Source:HGNC Symbol;Acc:HGNC:10056] | 740 | 1.737 | 0.8566 | Yes |
| 53 | ATF3 | activating transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:785] | 764 | 1.712 | 0.8658 | Yes |
| 54 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 784 | 1.686 | 0.8750 | Yes |
| 55 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 1106 | 1.392 | 0.8743 | Yes |
| 56 | EIF1 | eukaryotic translation initiation factor 1 [Source:HGNC Symbol;Acc:HGNC:3249] | 1125 | 1.378 | 0.8817 | Yes |
| 57 | JUND | JunD proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6206] | 1229 | 1.310 | 0.8864 | Yes |
| 58 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 1250 | 1.301 | 0.8933 | Yes |
| 59 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006] | 1273 | 1.288 | 0.9001 | Yes |
| 60 | IRGM | immunity related GTPase M [Source:HGNC Symbol;Acc:HGNC:29597] | 1481 | 1.161 | 0.9012 | Yes |
| 61 | WSB1 | WD repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:19221] | 1501 | 1.155 | 0.9073 | Yes |
| 62 | SLC2A1 | solute carrier family 2 member 1 [Source:HGNC Symbol;Acc:HGNC:11005] | 1510 | 1.151 | 0.9136 | Yes |
| 63 | TOP1 | DNA topoisomerase I [Source:HGNC Symbol;Acc:HGNC:11986] | 1606 | 1.107 | 0.9174 | Yes |
| 64 | MLLT11 | MLLT11 transcription factor 7 cofactor [Source:HGNC Symbol;Acc:HGNC:16997] | 2138 | 0.884 | 0.9081 | No |
| 65 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 2177 | 0.871 | 0.9121 | No |
| 66 | MAP2K1 | mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840] | 2801 | 0.683 | 0.8992 | No |
| 67 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 2866 | 0.664 | 0.9012 | No |
| 68 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 2991 | 0.632 | 0.9015 | No |
| 69 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 3722 | 0.467 | 0.8845 | No |
| 70 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 5250 | 0.201 | 0.8443 | No |
| 71 | RCN1 | reticulocalbin 1 [Source:HGNC Symbol;Acc:HGNC:9934] | 5934 | 0.100 | 0.8265 | No |
| 72 | FCGR2B | Fc fragment of IgG receptor IIb [Source:HGNC Symbol;Acc:HGNC:3618] | 6157 | 0.069 | 0.8209 | No |
| 73 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6626 | 0.000 | 0.8082 | No |
| 74 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 9054 | 0.000 | 0.7426 | No |
| 75 | SLPI | secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092] | 9495 | 0.000 | 0.7307 | No |
| 76 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 11629 | 0.000 | 0.6731 | No |
| 77 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13585 | 0.000 | 0.6203 | No |
| 78 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 27063 | 0.000 | 0.2561 | No |
| 79 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27977 | -0.029 | 0.2316 | No |
| 80 | MAPKAPK2 | MAPK activated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:6887] | 28346 | -0.083 | 0.2221 | No |
| 81 | KPNA3 | karyopherin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6396] | 28604 | -0.119 | 0.2159 | No |
| 82 | PRKCD | protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399] | 30343 | -0.362 | 0.1710 | No |
| 83 | SAP30 | Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532] | 31021 | -0.466 | 0.1553 | No |
| 84 | PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase type 1 beta [Source:HGNC Symbol;Acc:HGNC:8995] | 31266 | -0.505 | 0.1516 | No |
| 85 | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 [Source:HGNC Symbol;Acc:HGNC:1987] | 33433 | -0.998 | 0.0988 | No |
