Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | REACTOME_INTERLEUKIN_10_SIGNALING |
| Enrichment Score (ES) | 0.868082 |
| Normalized Enrichment Score (NES) | 1.9669188 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.001133711 |
| FWER p-Value | 0.006 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.989 | 0.0759 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 1 | 4.939 | 0.1510 | Yes |
| 3 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 2 | 4.930 | 0.2260 | Yes |
| 4 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 3 | 4.921 | 0.3008 | Yes |
| 5 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 4 | 4.887 | 0.3752 | Yes |
| 6 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 8 | 4.850 | 0.4489 | Yes |
| 7 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 9 | 4.813 | 0.5221 | Yes |
| 8 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 17 | 4.615 | 0.5921 | Yes |
| 9 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 41 | 4.239 | 0.6559 | Yes |
| 10 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 207 | 2.876 | 0.6952 | Yes |
| 11 | STAT3 | signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364] | 242 | 2.756 | 0.7362 | Yes |
| 12 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 398 | 2.258 | 0.7664 | Yes |
| 13 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 625 | 1.882 | 0.7889 | Yes |
| 14 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 711 | 1.779 | 0.8137 | Yes |
| 15 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 717 | 1.768 | 0.8404 | Yes |
| 16 | TNFRSF1A | TNF receptor superfamily member 1A [Source:HGNC Symbol;Acc:HGNC:11916] | 1012 | 1.464 | 0.8548 | Yes |
| 17 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 1728 | 1.050 | 0.8514 | Yes |
| 18 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 2033 | 0.923 | 0.8573 | Yes |
| 19 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 2132 | 0.886 | 0.8681 | Yes |
| 20 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 3416 | 0.533 | 0.8416 | No |
| 21 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 3429 | 0.530 | 0.8493 | No |
| 22 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 3563 | 0.500 | 0.8533 | No |
| 23 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 3652 | 0.483 | 0.8583 | No |
| 24 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 4000 | 0.415 | 0.8552 | No |
| 25 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4122 | 0.395 | 0.8580 | No |
| 26 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 4784 | 0.281 | 0.8444 | No |
| 27 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 5214 | 0.206 | 0.8359 | No |
| 28 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6616 | 0.000 | 0.7981 | No |
| 29 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6627 | 0.000 | 0.7979 | No |
| 30 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 13933 | 0.000 | 0.6007 | No |
| 31 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14892 | 0.000 | 0.5748 | No |
| 32 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14893 | 0.000 | 0.5748 | No |
| 33 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15970 | 0.000 | 0.5458 | No |
| 34 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 15971 | 0.000 | 0.5458 | No |
| 35 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18291 | 0.000 | 0.4832 | No |
| 36 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19471 | 0.000 | 0.4513 | No |
| 37 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19480 | 0.000 | 0.4511 | No |
| 38 | CD80 | CD80 molecule [Source:HGNC Symbol;Acc:HGNC:1700] | 23243 | 0.000 | 0.3496 | No |
| 39 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 24724 | 0.000 | 0.3096 | No |
| 40 | FCER2 | Fc fragment of IgE receptor II [Source:HGNC Symbol;Acc:HGNC:3612] | 26320 | 0.000 | 0.2666 | No |
| 41 | IL12A | interleukin 12A [Source:HGNC Symbol;Acc:HGNC:5969] | 27247 | 0.000 | 0.2416 | No |
| 42 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27977 | -0.029 | 0.2223 | No |
| 43 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 28229 | -0.068 | 0.2166 | No |
| 44 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 28392 | -0.088 | 0.2136 | No |
| 45 | IL10RB | interleukin 10 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:5965] | 32260 | -0.695 | 0.1197 | No |
| 46 | TYK2 | tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440] | 32274 | -0.698 | 0.1300 | No |
