Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | SANA_TNF_SIGNALING_UP |
| Enrichment Score (ES) | 0.77207553 |
| Normalized Enrichment Score (NES) | 1.9153211 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0024564222 |
| FWER p-Value | 0.021 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 26 | 4.440 | 0.0492 | Yes |
| 2 | PLA1A | phospholipase A1 member A [Source:HGNC Symbol;Acc:HGNC:17661] | 33 | 4.369 | 0.0982 | Yes |
| 3 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 99 | 3.487 | 0.1356 | Yes |
| 4 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 120 | 3.344 | 0.1726 | Yes |
| 5 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 122 | 3.323 | 0.2100 | Yes |
| 6 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 134 | 3.225 | 0.2459 | Yes |
| 7 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 201 | 2.898 | 0.2767 | Yes |
| 8 | ITGAV | integrin subunit alpha V [Source:HGNC Symbol;Acc:HGNC:6150] | 216 | 2.848 | 0.3083 | Yes |
| 9 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 223 | 2.834 | 0.3400 | Yes |
| 10 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 238 | 2.774 | 0.3708 | Yes |
| 11 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 240 | 2.767 | 0.4019 | Yes |
| 12 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 330 | 2.446 | 0.4270 | Yes |
| 13 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 372 | 2.318 | 0.4520 | Yes |
| 14 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 391 | 2.266 | 0.4769 | Yes |
| 15 | IFIH1 | interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873] | 412 | 2.243 | 0.5016 | Yes |
| 16 | TAPBP | TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566] | 476 | 2.123 | 0.5238 | Yes |
| 17 | SERPINE1 | serpin family E member 1 [Source:HGNC Symbol;Acc:HGNC:8583] | 492 | 2.096 | 0.5469 | Yes |
| 18 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 625 | 1.882 | 0.5645 | Yes |
| 19 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 626 | 1.880 | 0.5857 | Yes |
| 20 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 632 | 1.868 | 0.6065 | Yes |
| 21 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 635 | 1.863 | 0.6274 | Yes |
| 22 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 647 | 1.846 | 0.6479 | Yes |
| 23 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 719 | 1.760 | 0.6657 | Yes |
| 24 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 818 | 1.639 | 0.6815 | Yes |
| 25 | DNAJA1 | DnaJ heat shock protein family (Hsp40) member A1 [Source:HGNC Symbol;Acc:HGNC:5229] | 916 | 1.543 | 0.6962 | Yes |
| 26 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1097 | 1.398 | 0.7071 | Yes |
| 27 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 1106 | 1.392 | 0.7225 | Yes |
| 28 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 1396 | 1.208 | 0.7283 | Yes |
| 29 | LIPG | lipase G, endothelial type [Source:HGNC Symbol;Acc:HGNC:6623] | 1675 | 1.075 | 0.7329 | Yes |
| 30 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 1728 | 1.050 | 0.7433 | Yes |
| 31 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 1756 | 1.034 | 0.7541 | Yes |
| 32 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 2020 | 0.927 | 0.7575 | Yes |
| 33 | FTH1 | ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976] | 2048 | 0.919 | 0.7670 | Yes |
| 34 | RAC3 | Rac family small GTPase 3 [Source:HGNC Symbol;Acc:HGNC:9803] | 2225 | 0.851 | 0.7719 | Yes |
| 35 | HLA-B | major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:HGNC:4932] | 2531 | 0.752 | 0.7721 | Yes |
| 36 | RABL3 | RAB, member of RAS oncogene family like 3 [Source:HGNC Symbol;Acc:HGNC:18072] | 3857 | 0.443 | 0.7412 | No |
| 37 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 3910 | 0.434 | 0.7447 | No |
| 38 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 4000 | 0.415 | 0.7470 | No |
| 39 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4122 | 0.395 | 0.7482 | No |
| 40 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 4626 | 0.308 | 0.7380 | No |
| 41 | HLA-E | major histocompatibility complex, class I, E [Source:HGNC Symbol;Acc:HGNC:4962] | 4694 | 0.298 | 0.7396 | No |
| 42 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 5008 | 0.242 | 0.7338 | No |
| 43 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 5012 | 0.241 | 0.7365 | No |
| 44 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 5380 | 0.179 | 0.7285 | No |
| 45 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 5579 | 0.149 | 0.7249 | No |
| 46 | DRAM1 | DNA damage regulated autophagy modulator 1 [Source:HGNC Symbol;Acc:HGNC:25645] | 5816 | 0.121 | 0.7199 | No |
| 47 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 5903 | 0.106 | 0.7187 | No |
| 48 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 6146 | 0.071 | 0.7130 | No |
| 49 | ATP13A3 | ATPase 13A3 [Source:HGNC Symbol;Acc:HGNC:24113] | 6492 | 0.012 | 0.7038 | No |
| 50 | SPAG9 | sperm associated antigen 9 [Source:HGNC Symbol;Acc:HGNC:14524] | 6539 | 0.004 | 0.7026 | No |
| 51 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6597 | 0.000 | 0.7011 | No |
| 52 | PDGFRL | platelet derived growth factor receptor like [Source:HGNC Symbol;Acc:HGNC:8805] | 7748 | 0.000 | 0.6700 | No |
| 53 | APOL1 | apolipoprotein L1 [Source:HGNC Symbol;Acc:HGNC:618] | 10248 | 0.000 | 0.6025 | No |
| 54 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 10250 | 0.000 | 0.6024 | No |
| 55 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10904 | 0.000 | 0.5848 | No |
| 56 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11249 | 0.000 | 0.5755 | No |
| 57 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 11355 | 0.000 | 0.5727 | No |
| 58 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12608 | 0.000 | 0.5388 | No |
| 59 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 12936 | 0.000 | 0.5300 | No |
| 60 | IL32 | interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830] | 13967 | 0.000 | 0.5022 | No |
| 61 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 14022 | 0.000 | 0.5007 | No |
| 62 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18291 | 0.000 | 0.3854 | No |
| 63 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18946 | 0.000 | 0.3677 | No |
| 64 | CTHRC1 | collagen triple helix repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:18831] | 18971 | 0.000 | 0.3671 | No |
| 65 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19466 | 0.000 | 0.3537 | No |
| 66 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19471 | 0.000 | 0.3536 | No |
| 67 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 20924 | 0.000 | 0.3144 | No |
| 68 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 23062 | 0.000 | 0.2566 | No |
| 69 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 23064 | 0.000 | 0.2566 | No |
| 70 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 23875 | 0.000 | 0.2347 | No |
| 71 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 23940 | 0.000 | 0.2330 | No |
| 72 | ANO9 | anoctamin 9 [Source:HGNC Symbol;Acc:HGNC:20679] | 25281 | 0.000 | 0.1968 | No |
| 73 | SSPN | sarcospan [Source:HGNC Symbol;Acc:HGNC:11322] | 27380 | 0.000 | 0.1401 | No |
| 74 | C1QTNF1 | C1q and TNF related 1 [Source:HGNC Symbol;Acc:HGNC:14324] | 27983 | -0.029 | 0.1241 | No |
| 75 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 28392 | -0.088 | 0.1141 | No |
| 76 | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925] | 28821 | -0.146 | 0.1042 | No |
| 77 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 29798 | -0.290 | 0.0811 | No |
| 78 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 31480 | -0.541 | 0.0417 | No |
| 79 | NCEH1 | neutral cholesterol ester hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:29260] | 33084 | -0.893 | 0.0084 | No |
| 80 | BPGM | bisphosphoglycerate mutase [Source:HGNC Symbol;Acc:HGNC:1093] | 35189 | -1.666 | -0.0297 | No |
| 81 | OXR1 | oxidation resistance 1 [Source:HGNC Symbol;Acc:HGNC:15822] | 35461 | -1.813 | -0.0166 | No |
| 82 | RHOB | ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668] | 36189 | -2.355 | -0.0098 | No |
| 83 | SMAD3 | SMAD family member 3 [Source:HGNC Symbol;Acc:HGNC:6769] | 36690 | -3.034 | 0.0108 | No |
