Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | SEKI_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.8227417 |
| Normalized Enrichment Score (NES) | 2.0531218 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 10 | 4.787 | 0.0399 | Yes |
| 2 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 15 | 4.678 | 0.0791 | Yes |
| 3 | RND1 | Rho family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:18314] | 19 | 4.564 | 0.1173 | Yes |
| 4 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 26 | 4.440 | 0.1544 | Yes |
| 5 | ZC3H12A | zinc finger CCCH-type containing 12A [Source:HGNC Symbol;Acc:HGNC:26259] | 50 | 4.100 | 0.1882 | Yes |
| 6 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 56 | 4.026 | 0.2219 | Yes |
| 7 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 99 | 3.487 | 0.2500 | Yes |
| 8 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 102 | 3.437 | 0.2788 | Yes |
| 9 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 118 | 3.353 | 0.3066 | Yes |
| 10 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 122 | 3.323 | 0.3344 | Yes |
| 11 | SLC4A7 | solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033] | 145 | 3.177 | 0.3604 | Yes |
| 12 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 181 | 2.996 | 0.3846 | Yes |
| 13 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 192 | 2.933 | 0.4090 | Yes |
| 14 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 223 | 2.834 | 0.4320 | Yes |
| 15 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 240 | 2.767 | 0.4548 | Yes |
| 16 | SH3PXD2B | SH3 and PX domains 2B [Source:HGNC Symbol;Acc:HGNC:29242] | 265 | 2.673 | 0.4766 | Yes |
| 17 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 308 | 2.510 | 0.4965 | Yes |
| 18 | SLC11A2 | solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908] | 347 | 2.382 | 0.5155 | Yes |
| 19 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 363 | 2.348 | 0.5348 | Yes |
| 20 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 385 | 2.291 | 0.5534 | Yes |
| 21 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 391 | 2.266 | 0.5723 | Yes |
| 22 | CEMIP2 | cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869] | 461 | 2.141 | 0.5884 | Yes |
| 23 | ZMYND15 | zinc finger MYND-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20997] | 462 | 2.140 | 0.6064 | Yes |
| 24 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 475 | 2.124 | 0.6239 | Yes |
| 25 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 498 | 2.081 | 0.6408 | Yes |
| 26 | GBP6 | guanylate binding protein family member 6 [Source:HGNC Symbol;Acc:HGNC:25395] | 530 | 2.034 | 0.6570 | Yes |
| 27 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 593 | 1.932 | 0.6716 | Yes |
| 28 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 625 | 1.882 | 0.6865 | Yes |
| 29 | GSAP | gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042] | 651 | 1.841 | 0.7013 | Yes |
| 30 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 711 | 1.779 | 0.7146 | Yes |
| 31 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 719 | 1.760 | 0.7292 | Yes |
| 32 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 724 | 1.752 | 0.7438 | Yes |
| 33 | EXOC3L4 | exocyst complex component 3 like 4 [Source:HGNC Symbol;Acc:HGNC:20120] | 725 | 1.750 | 0.7585 | Yes |
| 34 | JDP2 | Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546] | 793 | 1.674 | 0.7707 | Yes |
| 35 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 909 | 1.547 | 0.7806 | Yes |
| 36 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 911 | 1.546 | 0.7936 | Yes |
| 37 | MAFF | MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] | 928 | 1.535 | 0.8060 | Yes |
| 38 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1097 | 1.398 | 0.8132 | Yes |
| 39 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 1437 | 1.186 | 0.8140 | Yes |
| 40 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 1477 | 1.163 | 0.8227 | Yes |
| 41 | SCHIP1 | schwannomin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:15678] | 2852 | 0.667 | 0.7912 | No |
| 42 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 3036 | 0.622 | 0.7915 | No |
| 43 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 3910 | 0.434 | 0.7716 | No |
| 44 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4122 | 0.395 | 0.7692 | No |
| 45 | FAS | Fas cell surface death receptor [Source:HGNC Symbol;Acc:HGNC:11920] | 4145 | 0.393 | 0.7719 | No |
| 46 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 5008 | 0.242 | 0.7506 | No |
| 47 | SELE | selectin E [Source:HGNC Symbol;Acc:HGNC:10718] | 7378 | 0.000 | 0.6866 | No |
| 48 | PRRX1 | paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142] | 8811 | 0.000 | 0.6479 | No |
| 49 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8943 | 0.000 | 0.6444 | No |
| 50 | NGFR | nerve growth factor receptor [Source:HGNC Symbol;Acc:HGNC:7809] | 10507 | 0.000 | 0.6022 | No |
| 51 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 11355 | 0.000 | 0.5793 | No |
| 52 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11655 | 0.000 | 0.5712 | No |
| 53 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 14022 | 0.000 | 0.5073 | No |
| 54 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 17832 | 0.000 | 0.4044 | No |
| 55 | LRATD1 | LRAT domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20743] | 18072 | 0.000 | 0.3979 | No |
| 56 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18291 | 0.000 | 0.3920 | No |
| 57 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18912 | 0.000 | 0.3753 | No |
| 58 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 19026 | 0.000 | 0.3722 | No |
| 59 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19466 | 0.000 | 0.3604 | No |
| 60 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19480 | 0.000 | 0.3600 | No |
| 61 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 19879 | 0.000 | 0.3492 | No |
| 62 | ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif 7 [Source:HGNC Symbol;Acc:HGNC:223] | 20064 | 0.000 | 0.3443 | No |
| 63 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 22245 | 0.000 | 0.2854 | No |
| 64 | EGFR | epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236] | 22280 | 0.000 | 0.2845 | No |
| 65 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 23064 | 0.000 | 0.2633 | No |
| 66 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 27063 | 0.000 | 0.1553 | No |
| 67 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 27878 | -0.014 | 0.1334 | No |
| 68 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27977 | -0.029 | 0.1310 | No |
| 69 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 28392 | -0.088 | 0.1206 | No |
| 70 | BIRC2 | baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590] | 32757 | -0.814 | 0.0095 | No |
| 71 | NEURL3 | neuralized E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:25162] | 33359 | -0.974 | 0.0014 | No |
| 72 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 33519 | -1.025 | 0.0057 | No |
| 73 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 33799 | -1.111 | 0.0075 | No |
| 74 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 34027 | -1.192 | 0.0114 | No |
| 75 | SLCO4A1 | solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953] | 35038 | -1.592 | -0.0025 | No |
| 76 | TJP2 | tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828] | 35490 | -1.830 | 0.0007 | No |
| 77 | RFX5 | regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986] | 36213 | -2.377 | 0.0011 | No |
| 78 | BMP2 | bone morphogenetic protein 2 [Source:HGNC Symbol;Acc:HGNC:1069] | 36479 | -2.689 | 0.0165 | No |
