Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | WHITEFORD_PEDIATRIC_CANCER_MARKERS |
| Enrichment Score (ES) | -0.76787245 |
| Normalized Enrichment Score (NES) | -1.6643858 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.003459336 |
| FWER p-Value | 0.071 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 61 | 3.985 | 0.0217 | No |
| 2 | BCAT1 | branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976] | 277 | 2.648 | 0.0314 | No |
| 3 | NME1 | NME/NM23 nucleoside diphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:7849] | 573 | 1.961 | 0.0350 | No |
| 4 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1504 | 1.154 | 0.0166 | No |
| 5 | MLLT11 | MLLT11 transcription factor 7 cofactor [Source:HGNC Symbol;Acc:HGNC:16997] | 2138 | 0.884 | 0.0047 | No |
| 6 | CDK6 | cyclin dependent kinase 6 [Source:HGNC Symbol;Acc:HGNC:1777] | 2299 | 0.828 | 0.0052 | No |
| 7 | CDC25A | cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725] | 3222 | 0.578 | -0.0164 | No |
| 8 | EIF4A1 | eukaryotic translation initiation factor 4A1 [Source:HGNC Symbol;Acc:HGNC:3282] | 3932 | 0.429 | -0.0330 | No |
| 9 | CCNT1 | cyclin T1 [Source:HGNC Symbol;Acc:HGNC:1599] | 3983 | 0.419 | -0.0319 | No |
| 10 | TMEFF1 | transmembrane protein with EGF like and two follistatin like domains 1 [Source:HGNC Symbol;Acc:HGNC:11866] | 4149 | 0.392 | -0.0341 | No |
| 11 | ILF2 | interleukin enhancer binding factor 2 [Source:HGNC Symbol;Acc:HGNC:6037] | 4434 | 0.339 | -0.0398 | No |
| 12 | EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3288] | 4511 | 0.325 | -0.0399 | No |
| 13 | MFN2 | mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877] | 4641 | 0.305 | -0.0416 | No |
| 14 | GPX7 | glutathione peroxidase 7 [Source:HGNC Symbol;Acc:HGNC:4559] | 9668 | 0.000 | -0.1776 | No |
| 15 | H4C3 | H4 clustered histone 3 [Source:HGNC Symbol;Acc:HGNC:4787] | 10337 | 0.000 | -0.1956 | No |
| 16 | KLKB1 | kallikrein B1 [Source:HGNC Symbol;Acc:HGNC:6371] | 11295 | 0.000 | -0.2215 | No |
| 17 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16775 | 0.000 | -0.3697 | No |
| 18 | TWIST1 | twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428] | 17292 | 0.000 | -0.3836 | No |
| 19 | GABRB2 | gamma-aminobutyric acid type A receptor subunit beta2 [Source:HGNC Symbol;Acc:HGNC:4082] | 19953 | 0.000 | -0.4556 | No |
| 20 | SNORD22 | small nucleolar RNA, C/D box 22 [Source:HGNC Symbol;Acc:HGNC:10145] | 22475 | 0.000 | -0.5238 | No |
| 21 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 24301 | 0.000 | -0.5731 | No |
| 22 | SOX4 | SRY-box transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:11200] | 26410 | 0.000 | -0.6301 | No |
| 23 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26430 | 0.000 | -0.6307 | No |
| 24 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27912 | -0.021 | -0.6706 | No |
| 25 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 27938 | -0.026 | -0.6711 | No |
| 26 | JPT1 | Jupiter microtubule associated homolog 1 [Source:HGNC Symbol;Acc:HGNC:14569] | 28159 | -0.057 | -0.6767 | No |
| 27 | ZNF300 | zinc finger protein 300 [Source:HGNC Symbol;Acc:HGNC:13091] | 28416 | -0.091 | -0.6831 | No |
| 28 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 28646 | -0.123 | -0.6886 | No |
| 29 | POLQ | DNA polymerase theta [Source:HGNC Symbol;Acc:HGNC:9186] | 28779 | -0.141 | -0.6913 | No |
| 30 | ZMYM2 | zinc finger MYM-type containing 2 [Source:HGNC Symbol;Acc:HGNC:12989] | 28986 | -0.169 | -0.6959 | No |
| 31 | GGH | gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] | 29206 | -0.201 | -0.7006 | No |
| 32 | ENO1 | enolase 1 [Source:HGNC Symbol;Acc:HGNC:3350] | 29354 | -0.225 | -0.7033 | No |
| 33 | ADGRL3 | adhesion G protein-coupled receptor L3 [Source:HGNC Symbol;Acc:HGNC:20974] | 29776 | -0.286 | -0.7130 | No |
| 34 | RRP1 | ribosomal RNA processing 1 [Source:HGNC Symbol;Acc:HGNC:18785] | 30008 | -0.318 | -0.7174 | No |
| 35 | ILF3 | interleukin enhancer binding factor 3 [Source:HGNC Symbol;Acc:HGNC:6038] | 30768 | -0.428 | -0.7354 | No |
| 36 | SNRNP200 | small nuclear ribonucleoprotein U5 subunit 200 [Source:HGNC Symbol;Acc:HGNC:30859] | 31316 | -0.513 | -0.7472 | No |
| 37 | RCC2 | regulator of chromosome condensation 2 [Source:HGNC Symbol;Acc:HGNC:30297] | 31493 | -0.544 | -0.7488 | No |
| 38 | PSAT1 | phosphoserine aminotransferase 1 [Source:HGNC Symbol;Acc:HGNC:19129] | 32025 | -0.646 | -0.7593 | No |
| 39 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 32085 | -0.659 | -0.7571 | No |
| 40 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 32214 | -0.686 | -0.7565 | No |
| 41 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 32625 | -0.776 | -0.7630 | Yes |
| 42 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32700 | -0.796 | -0.7604 | Yes |
| 43 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 32783 | -0.819 | -0.7578 | Yes |
| 44 | LMNB2 | lamin B2 [Source:HGNC Symbol;Acc:HGNC:6638] | 33031 | -0.881 | -0.7593 | Yes |
| 45 | MND1 | meiotic nuclear divisions 1 [Source:HGNC Symbol;Acc:HGNC:24839] | 33349 | -0.972 | -0.7622 | Yes |
| 46 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33479 | -1.012 | -0.7597 | Yes |
| 47 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33690 | -1.077 | -0.7591 | Yes |
| 48 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 33697 | -1.078 | -0.7529 | Yes |
| 49 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33713 | -1.082 | -0.7470 | Yes |
| 50 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33721 | -1.084 | -0.7408 | Yes |
| 51 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 33914 | -1.155 | -0.7392 | Yes |
| 52 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 33947 | -1.167 | -0.7333 | Yes |
| 53 | ZNF367 | zinc finger protein 367 [Source:HGNC Symbol;Acc:HGNC:18320] | 34053 | -1.200 | -0.7291 | Yes |
| 54 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141] | 34158 | -1.229 | -0.7247 | Yes |
| 55 | CDK4 | cyclin dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773] | 34451 | -1.336 | -0.7247 | Yes |
| 56 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 34562 | -1.376 | -0.7196 | Yes |
| 57 | ADCY3 | adenylate cyclase 3 [Source:HGNC Symbol;Acc:HGNC:234] | 34598 | -1.390 | -0.7124 | Yes |
| 58 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 34637 | -1.405 | -0.7052 | Yes |
| 59 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34655 | -1.411 | -0.6974 | Yes |
| 60 | NUDT1 | nudix hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:8048] | 34724 | -1.434 | -0.6908 | Yes |
| 61 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 34894 | -1.508 | -0.6865 | Yes |
| 62 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34896 | -1.510 | -0.6777 | Yes |
| 63 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 34952 | -1.544 | -0.6701 | Yes |
| 64 | RNASEH2A | ribonuclease H2 subunit A [Source:HGNC Symbol;Acc:HGNC:18518] | 35022 | -1.580 | -0.6627 | Yes |
| 65 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35131 | -1.642 | -0.6560 | Yes |
| 66 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35165 | -1.659 | -0.6472 | Yes |
| 67 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35266 | -1.714 | -0.6398 | Yes |
| 68 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35303 | -1.732 | -0.6306 | Yes |
| 69 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 35304 | -1.732 | -0.6205 | Yes |
| 70 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35315 | -1.737 | -0.6106 | Yes |
| 71 | PON3 | paraoxonase 3 [Source:HGNC Symbol;Acc:HGNC:9206] | 35370 | -1.762 | -0.6017 | Yes |
| 72 | CCDC34 | coiled-coil domain containing 34 [Source:HGNC Symbol;Acc:HGNC:25079] | 35451 | -1.809 | -0.5932 | Yes |
| 73 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35527 | -1.854 | -0.5844 | Yes |
| 74 | RECQL4 | RecQ like helicase 4 [Source:HGNC Symbol;Acc:HGNC:9949] | 35599 | -1.907 | -0.5751 | Yes |
| 75 | CDCA2 | cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623] | 35638 | -1.929 | -0.5648 | Yes |
| 76 | CENPN | centromere protein N [Source:HGNC Symbol;Acc:HGNC:30873] | 35643 | -1.931 | -0.5536 | Yes |
| 77 | MEX3B | mex-3 RNA binding family member B [Source:HGNC Symbol;Acc:HGNC:25297] | 35721 | -1.994 | -0.5440 | Yes |
| 78 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35736 | -2.006 | -0.5326 | Yes |
| 79 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35755 | -2.023 | -0.5212 | Yes |
| 80 | HAUS1 | HAUS augmin like complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:25174] | 35756 | -2.023 | -0.5094 | Yes |
| 81 | CENPU | centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348] | 35816 | -2.070 | -0.4988 | Yes |
| 82 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 35868 | -2.107 | -0.4879 | Yes |
| 83 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 35886 | -2.120 | -0.4759 | Yes |
| 84 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35889 | -2.122 | -0.4635 | Yes |
| 85 | UHRF1 | ubiquitin like with PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:12556] | 35897 | -2.126 | -0.4512 | Yes |
| 86 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35922 | -2.150 | -0.4392 | Yes |
| 87 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35930 | -2.153 | -0.4268 | Yes |
| 88 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35935 | -2.155 | -0.4143 | Yes |
| 89 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.4021 | Yes |
| 90 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35963 | -2.182 | -0.3894 | Yes |
| 91 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35968 | -2.186 | -0.3767 | Yes |
| 92 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36015 | -2.212 | -0.3649 | Yes |
| 93 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36049 | -2.239 | -0.3527 | Yes |
| 94 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36062 | -2.250 | -0.3398 | Yes |
| 95 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.3270 | Yes |
| 96 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36099 | -2.278 | -0.3141 | Yes |
| 97 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36191 | -2.357 | -0.3028 | Yes |
| 98 | MYCN | MYCN proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7559] | 36198 | -2.363 | -0.2891 | Yes |
| 99 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36232 | -2.394 | -0.2759 | Yes |
| 100 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36238 | -2.399 | -0.2620 | Yes |
| 101 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36249 | -2.411 | -0.2481 | Yes |
| 102 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 36277 | -2.444 | -0.2345 | Yes |
| 103 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36289 | -2.458 | -0.2204 | Yes |
| 104 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36304 | -2.474 | -0.2063 | Yes |
| 105 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36360 | -2.539 | -0.1928 | Yes |
| 106 | ATAD2 | ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123] | 36387 | -2.570 | -0.1785 | Yes |
| 107 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36438 | -2.629 | -0.1644 | Yes |
| 108 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36470 | -2.674 | -0.1496 | Yes |
| 109 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36546 | -2.789 | -0.1352 | Yes |
| 110 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36555 | -2.800 | -0.1190 | Yes |
| 111 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36643 | -2.941 | -0.1041 | Yes |
| 112 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36679 | -3.000 | -0.0875 | Yes |
| 113 | PAFAH1B3 | platelet activating factor acetylhydrolase 1b catalytic subunit 3 [Source:HGNC Symbol;Acc:HGNC:8576] | 36709 | -3.062 | -0.0703 | Yes |
| 114 | SLC25A40 | solute carrier family 25 member 40 [Source:HGNC Symbol;Acc:HGNC:29680] | 36748 | -3.155 | -0.0528 | Yes |
| 115 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36757 | -3.180 | -0.0344 | Yes |
| 116 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36787 | -3.234 | -0.0162 | Yes |
| 117 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37029 | -4.153 | 0.0016 | Yes |
