Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | WORSCHECH_TUMOR_REJECTION_UP |
| Enrichment Score (ES) | 0.81413376 |
| Normalized Enrichment Score (NES) | 1.9154949 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0026453778 |
| FWER p-Value | 0.021 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.989 | 0.0884 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 4 | 4.887 | 0.1750 | Yes |
| 3 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 8 | 4.850 | 0.2608 | Yes |
| 4 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 10 | 4.787 | 0.3457 | Yes |
| 5 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 17 | 4.615 | 0.4273 | Yes |
| 6 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 44 | 4.185 | 0.5008 | Yes |
| 7 | IL4I1 | interleukin 4 induced 1 [Source:HGNC Symbol;Acc:HGNC:19094] | 55 | 4.029 | 0.5719 | Yes |
| 8 | MSR1 | macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376] | 213 | 2.857 | 0.6183 | Yes |
| 9 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 406 | 2.252 | 0.6531 | Yes |
| 10 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 484 | 2.110 | 0.6884 | Yes |
| 11 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 635 | 1.863 | 0.7174 | Yes |
| 12 | TLR6 | toll like receptor 6 [Source:HGNC Symbol;Acc:HGNC:16711] | 722 | 1.754 | 0.7461 | Yes |
| 13 | ALCAM | activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400] | 931 | 1.533 | 0.7677 | Yes |
| 14 | IL2RG | interleukin 2 receptor subunit gamma [Source:HGNC Symbol;Acc:HGNC:6010] | 1310 | 1.267 | 0.7799 | Yes |
| 15 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 1493 | 1.158 | 0.7955 | Yes |
| 16 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 1728 | 1.050 | 0.8078 | Yes |
| 17 | NKRF | NFKB repressing factor [Source:HGNC Symbol;Acc:HGNC:19374] | 2085 | 0.898 | 0.8141 | Yes |
| 18 | IRF6 | interferon regulatory factor 6 [Source:HGNC Symbol;Acc:HGNC:6121] | 3038 | 0.622 | 0.7994 | No |
| 19 | EBF4 | EBF family member 4 [Source:HGNC Symbol;Acc:HGNC:29278] | 3453 | 0.523 | 0.7975 | No |
| 20 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 3910 | 0.434 | 0.7929 | No |
| 21 | IRF4 | interferon regulatory factor 4 [Source:HGNC Symbol;Acc:HGNC:6119] | 4048 | 0.407 | 0.7964 | No |
| 22 | CKLF | chemokine like factor [Source:HGNC Symbol;Acc:HGNC:13253] | 4068 | 0.405 | 0.8031 | No |
| 23 | IL7 | interleukin 7 [Source:HGNC Symbol;Acc:HGNC:6023] | 4387 | 0.346 | 0.8006 | No |
| 24 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 4586 | 0.313 | 0.8008 | No |
| 25 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 5012 | 0.241 | 0.7936 | No |
| 26 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6597 | 0.000 | 0.7509 | No |
| 27 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6626 | 0.000 | 0.7501 | No |
| 28 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6627 | 0.000 | 0.7501 | No |
| 29 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8943 | 0.000 | 0.6876 | No |
| 30 | LY6H | lymphocyte antigen 6 family member H [Source:HGNC Symbol;Acc:HGNC:6728] | 9409 | 0.000 | 0.6750 | No |
| 31 | TNFRSF4 | TNF receptor superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:11918] | 9936 | 0.000 | 0.6608 | No |
| 32 | ACKR1 | atypical chemokine receptor 1 (Duffy blood group) [Source:HGNC Symbol;Acc:HGNC:4035] | 11251 | 0.000 | 0.6253 | No |
| 33 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 11629 | 0.000 | 0.6152 | No |
| 34 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12324 | 0.000 | 0.5964 | No |
| 35 | TNFSF11 | TNF superfamily member 11 [Source:HGNC Symbol;Acc:HGNC:11926] | 12579 | 0.000 | 0.5896 | No |
| 36 | TCL1B | T cell leukemia/lymphoma 1B [Source:HGNC Symbol;Acc:HGNC:11649] | 13210 | 0.000 | 0.5725 | No |
| 37 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13585 | 0.000 | 0.5624 | No |
| 38 | IL31 | interleukin 31 [Source:HGNC Symbol;Acc:HGNC:19372] | 13972 | 0.000 | 0.5520 | No |
| 39 | TLX1 | T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056] | 14467 | 0.000 | 0.5387 | No |
| 40 | IL17RB | interleukin 17 receptor B [Source:HGNC Symbol;Acc:HGNC:18015] | 15207 | 0.000 | 0.5187 | No |
| 41 | IL36G | interleukin 36 gamma [Source:HGNC Symbol;Acc:HGNC:15741] | 15746 | 0.000 | 0.5042 | No |
| 42 | CLEC10A | C-type lectin domain containing 10A [Source:HGNC Symbol;Acc:HGNC:16916] | 15838 | 0.000 | 0.5017 | No |
| 43 | IL23R | interleukin 23 receptor [Source:HGNC Symbol;Acc:HGNC:19100] | 15966 | 0.000 | 0.4983 | No |
| 44 | IL5 | interleukin 5 [Source:HGNC Symbol;Acc:HGNC:6016] | 17771 | 0.000 | 0.4496 | No |
| 45 | ITK | IL2 inducible T cell kinase [Source:HGNC Symbol;Acc:HGNC:6171] | 17833 | 0.000 | 0.4479 | No |
| 46 | IFNA13 | interferon alpha 13 [Source:HGNC Symbol;Acc:HGNC:5419] | 18216 | 0.000 | 0.4376 | No |
| 47 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18946 | 0.000 | 0.4179 | No |
| 48 | FASLG | Fas ligand [Source:HGNC Symbol;Acc:HGNC:11936] | 20291 | 0.000 | 0.3816 | No |
| 49 | IFNG | interferon gamma [Source:HGNC Symbol;Acc:HGNC:5438] | 20833 | 0.000 | 0.3670 | No |
| 50 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 23062 | 0.000 | 0.3069 | No |
| 51 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 23072 | 0.000 | 0.3066 | No |
| 52 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 24162 | 0.000 | 0.2772 | No |
| 53 | IL17F | interleukin 17F [Source:HGNC Symbol;Acc:HGNC:16404] | 27307 | 0.000 | 0.1923 | No |
| 54 | JCHAIN | joining chain of multimeric IgA and IgM [Source:HGNC Symbol;Acc:HGNC:5713] | 27706 | 0.000 | 0.1815 | No |
| 55 | STAT6 | signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368] | 28266 | -0.073 | 0.1677 | No |
| 56 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 29283 | -0.213 | 0.1441 | No |
| 57 | CCR10 | C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474] | 29525 | -0.245 | 0.1419 | No |
| 58 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 30371 | -0.365 | 0.1256 | No |
| 59 | TAGAP | T cell activation RhoGTPase activating protein [Source:HGNC Symbol;Acc:HGNC:15669] | 30541 | -0.390 | 0.1279 | No |
| 60 | NFAT5 | nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774] | 32010 | -0.643 | 0.0997 | No |
| 61 | TLR4 | toll like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850] | 32959 | -0.864 | 0.0894 | No |
| 62 | NKIRAS2 | NFKB inhibitor interacting Ras like 2 [Source:HGNC Symbol;Acc:HGNC:17898] | 34213 | -1.249 | 0.0777 | No |
