Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 |
| Enrichment Score (ES) | -0.84066105 |
| Normalized Enrichment Score (NES) | -1.6675588 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0035788803 |
| FWER p-Value | 0.065 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:HGNC:5033] | 1777 | 1.023 | -0.0348 | No |
| 2 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 3722 | 0.467 | -0.0813 | No |
| 3 | NPM1 | nucleophosmin 1 [Source:HGNC Symbol;Acc:HGNC:7910] | 5103 | 0.222 | -0.1157 | No |
| 4 | P4HA1 | prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546] | 5754 | 0.129 | -0.1316 | No |
| 5 | TRIM44 | tripartite motif containing 44 [Source:HGNC Symbol;Acc:HGNC:19016] | 5993 | 0.090 | -0.1368 | No |
| 6 | ZNF84 | zinc finger protein 84 [Source:HGNC Symbol;Acc:HGNC:13159] | 7109 | 0.000 | -0.1669 | No |
| 7 | FAT2 | FAT atypical cadherin 2 [Source:HGNC Symbol;Acc:HGNC:3596] | 8246 | 0.000 | -0.1976 | No |
| 8 | SERPINI2 | serpin family I member 2 [Source:HGNC Symbol;Acc:HGNC:8945] | 17829 | 0.000 | -0.4563 | No |
| 9 | CCN1 | cellular communication network factor 1 [Source:HGNC Symbol;Acc:HGNC:2654] | 23100 | 0.000 | -0.5986 | No |
| 10 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27912 | -0.021 | -0.7282 | No |
| 11 | HMGB1P5 | high mobility group box 1 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:4997] | 29569 | -0.252 | -0.7697 | No |
| 12 | VEGFA | vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680] | 30658 | -0.411 | -0.7938 | No |
| 13 | TCN2 | transcobalamin 2 [Source:HGNC Symbol;Acc:HGNC:11653] | 31125 | -0.480 | -0.8002 | No |
| 14 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 32625 | -0.776 | -0.8307 | Yes |
| 15 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32700 | -0.796 | -0.8224 | Yes |
| 16 | BIRC2 | baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590] | 32757 | -0.814 | -0.8135 | Yes |
| 17 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33267 | -0.949 | -0.8150 | Yes |
| 18 | PARP2 | poly(ADP-ribose) polymerase 2 [Source:HGNC Symbol;Acc:HGNC:272] | 33340 | -0.969 | -0.8045 | Yes |
| 19 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33479 | -1.012 | -0.7952 | Yes |
| 20 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33713 | -1.082 | -0.7875 | Yes |
| 21 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34522 | -1.361 | -0.7918 | Yes |
| 22 | KNTC1 | kinetochore associated 1 [Source:HGNC Symbol;Acc:HGNC:17255] | 34524 | -1.362 | -0.7743 | Yes |
| 23 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 34562 | -1.376 | -0.7576 | Yes |
| 24 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34655 | -1.411 | -0.7419 | Yes |
| 25 | ZBTB5 | zinc finger and BTB domain containing 5 [Source:HGNC Symbol;Acc:HGNC:23836] | 34797 | -1.460 | -0.7270 | Yes |
| 26 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 34894 | -1.508 | -0.7102 | Yes |
| 27 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 34952 | -1.544 | -0.6918 | Yes |
| 28 | TUBB3 | tubulin beta 3 class III [Source:HGNC Symbol;Acc:HGNC:20772] | 34958 | -1.547 | -0.6721 | Yes |
| 29 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35012 | -1.573 | -0.6533 | Yes |
| 30 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 35028 | -1.585 | -0.6333 | Yes |
| 31 | TUBB4A | tubulin beta 4A class IVa [Source:HGNC Symbol;Acc:HGNC:20774] | 35203 | -1.676 | -0.6164 | Yes |
| 32 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35315 | -1.737 | -0.5970 | Yes |
| 33 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35455 | -1.811 | -0.5775 | Yes |
| 34 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35493 | -1.831 | -0.5549 | Yes |
| 35 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35527 | -1.854 | -0.5320 | Yes |
| 36 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35736 | -2.006 | -0.5118 | Yes |
| 37 | NCAPD3 | non-SMC condensin II complex subunit D3 [Source:HGNC Symbol;Acc:HGNC:28952] | 35822 | -2.072 | -0.4874 | Yes |
| 38 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35912 | -2.142 | -0.4622 | Yes |
| 39 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35935 | -2.155 | -0.4351 | Yes |
| 40 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35968 | -2.186 | -0.4078 | Yes |
| 41 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36012 | -2.211 | -0.3805 | Yes |
| 42 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36024 | -2.225 | -0.3522 | Yes |
| 43 | ANLN | anillin actin binding protein [Source:HGNC Symbol;Acc:HGNC:14082] | 36095 | -2.274 | -0.3248 | Yes |
| 44 | EXO1 | exonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3511] | 36172 | -2.347 | -0.2967 | Yes |
| 45 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36249 | -2.411 | -0.2677 | Yes |
| 46 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36286 | -2.451 | -0.2371 | Yes |
| 47 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36326 | -2.499 | -0.2060 | Yes |
| 48 | ATAD2 | ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123] | 36387 | -2.570 | -0.1746 | Yes |
| 49 | CEP55 | centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161] | 36433 | -2.620 | -0.1421 | Yes |
| 50 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36454 | -2.651 | -0.1085 | Yes |
| 51 | MIS18BP1 | MIS18 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20190] | 36694 | -3.042 | -0.0758 | Yes |
| 52 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36747 | -3.148 | -0.0367 | Yes |
| 53 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 36899 | -3.571 | 0.0052 | Yes |
