Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | GGGNNTTTCC_NFKB_Q6_01 |
| Enrichment Score (ES) | 0.48031014 |
| Normalized Enrichment Score (NES) | 1.2685095 |
| Nominal p-value | 0.028301887 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 3 | 4.921 | 0.0387 | Yes |
| 2 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 4 | 4.887 | 0.0772 | Yes |
| 3 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 17 | 4.615 | 0.1132 | Yes |
| 4 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 32 | 4.402 | 0.1475 | Yes |
| 5 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 54 | 4.052 | 0.1788 | Yes |
| 6 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 99 | 3.487 | 0.2051 | Yes |
| 7 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 118 | 3.353 | 0.2310 | Yes |
| 8 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 122 | 3.323 | 0.2571 | Yes |
| 9 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 271 | 2.660 | 0.2740 | Yes |
| 10 | CCND2 | cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583] | 348 | 2.377 | 0.2907 | Yes |
| 11 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 385 | 2.291 | 0.3078 | Yes |
| 12 | RYBP | RING1 and YY1 binding protein [Source:HGNC Symbol;Acc:HGNC:10480] | 439 | 2.180 | 0.3235 | Yes |
| 13 | FHL3 | four and a half LIM domains 3 [Source:HGNC Symbol;Acc:HGNC:3704] | 542 | 2.014 | 0.3366 | Yes |
| 14 | RAP2C | RAP2C, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:21165] | 576 | 1.957 | 0.3511 | Yes |
| 15 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 608 | 1.907 | 0.3653 | Yes |
| 16 | CCDC80 | coiled-coil domain containing 80 [Source:HGNC Symbol;Acc:HGNC:30649] | 682 | 1.820 | 0.3777 | Yes |
| 17 | SH2B3 | SH2B adaptor protein 3 [Source:HGNC Symbol;Acc:HGNC:29605] | 778 | 1.693 | 0.3884 | Yes |
| 18 | PFN1 | profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881] | 781 | 1.686 | 0.4016 | Yes |
| 19 | CPEB4 | cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21747] | 875 | 1.580 | 0.4116 | Yes |
| 20 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 959 | 1.508 | 0.4212 | Yes |
| 21 | ORAI1 | ORAI calcium release-activated calcium modulator 1 [Source:HGNC Symbol;Acc:HGNC:25896] | 1026 | 1.454 | 0.4309 | Yes |
| 22 | BATF | basic leucine zipper ATF-like transcription factor [Source:HGNC Symbol;Acc:HGNC:958] | 1101 | 1.394 | 0.4398 | Yes |
| 23 | ZFAND3 | zinc finger AN1-type containing 3 [Source:HGNC Symbol;Acc:HGNC:18019] | 1269 | 1.290 | 0.4455 | Yes |
| 24 | IER5 | immediate early response 5 [Source:HGNC Symbol;Acc:HGNC:5393] | 1502 | 1.155 | 0.4483 | Yes |
| 25 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 1812 | 1.012 | 0.4479 | Yes |
| 26 | GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28804] | 1864 | 0.992 | 0.4543 | Yes |
| 27 | TPM3 | tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012] | 2140 | 0.883 | 0.4538 | Yes |
| 28 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 2174 | 0.871 | 0.4598 | Yes |
| 29 | TFEC | transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754] | 2233 | 0.850 | 0.4649 | Yes |
| 30 | WNT10A | Wnt family member 10A [Source:HGNC Symbol;Acc:HGNC:13829] | 2388 | 0.794 | 0.4670 | Yes |
| 31 | UBE2M | ubiquitin conjugating enzyme E2 M [Source:HGNC Symbol;Acc:HGNC:12491] | 2410 | 0.789 | 0.4727 | Yes |
| 32 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 2613 | 0.729 | 0.4729 | Yes |
| 33 | RSPRY1 | ring finger and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29420] | 2858 | 0.665 | 0.4716 | Yes |
| 34 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 2991 | 0.632 | 0.4730 | Yes |
| 35 | RBMS1 | RNA binding motif single stranded interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9907] | 2993 | 0.632 | 0.4779 | Yes |
| 36 | TNFSF15 | TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931] | 3191 | 0.586 | 0.4772 | Yes |
| 37 | ETV1 | ETS variant transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3490] | 3244 | 0.572 | 0.4803 | Yes |
| 38 | UPF2 | UPF2 regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:17854] | 3520 | 0.508 | 0.4769 | No |
| 39 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 3563 | 0.500 | 0.4797 | No |
| 40 | FUT7 | fucosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4018] | 4366 | 0.349 | 0.4607 | No |
| 41 | SLAMF8 | SLAM family member 8 [Source:HGNC Symbol;Acc:HGNC:21391] | 4499 | 0.327 | 0.4597 | No |
| 42 | KY | kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:HGNC:26576] | 4607 | 0.310 | 0.4593 | No |
| 43 | G3BP1 | G3BP stress granule assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30292] | 4798 | 0.278 | 0.4563 | No |
| 44 | CDC27 | cell division cycle 27 [Source:HGNC Symbol;Acc:HGNC:1728] | 4924 | 0.257 | 0.4550 | No |
| 45 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 5008 | 0.242 | 0.4546 | No |
| 46 | SMPD3 | sphingomyelin phosphodiesterase 3 [Source:HGNC Symbol;Acc:HGNC:14240] | 5013 | 0.241 | 0.4564 | No |
| 47 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 5250 | 0.201 | 0.4516 | No |
| 48 | ENTHD1 | ENTH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26352] | 5575 | 0.150 | 0.4440 | No |
| 49 | N4BP1 | NEDD4 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29850] | 5842 | 0.116 | 0.4377 | No |
| 50 | CXCR5 | C-X-C motif chemokine receptor 5 [Source:HGNC Symbol;Acc:HGNC:1060] | 5980 | 0.092 | 0.4347 | No |
| 51 | WRAP53 | WD repeat containing antisense to TP53 [Source:HGNC Symbol;Acc:HGNC:25522] | 6083 | 0.083 | 0.4326 | No |
| 52 | MAML2 | mastermind like transcriptional coactivator 2 [Source:HGNC Symbol;Acc:HGNC:16259] | 6509 | 0.009 | 0.4212 | No |
| 53 | GREM1 | gremlin 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:2001] | 8449 | 0.000 | 0.3687 | No |
| 54 | POU2F3 | POU class 2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:19864] | 8633 | 0.000 | 0.3638 | No |
| 55 | DCLK1 | doublecortin like kinase 1 [Source:HGNC Symbol;Acc:HGNC:2700] | 8875 | 0.000 | 0.3573 | No |
| 56 | PRR34 | PRR34 long non-coding RNA [Source:HGNC Symbol;Acc:HGNC:25606] | 9059 | 0.000 | 0.3523 | No |
| 57 | MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:6765] | 9315 | 0.000 | 0.3454 | No |
| 58 | TNFRSF9 | TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924] | 9976 | 0.000 | 0.3276 | No |
| 59 | KCNS3 | potassium voltage-gated channel modifier subfamily S member 3 [Source:HGNC Symbol;Acc:HGNC:6302] | 10087 | 0.000 | 0.3246 | No |
| 60 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 10492 | 0.000 | 0.3136 | No |
| 61 | IL1RAPL1 | interleukin 1 receptor accessory protein like 1 [Source:HGNC Symbol;Acc:HGNC:5996] | 10578 | 0.000 | 0.3113 | No |
| 62 | NRIP2 | nuclear receptor interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:23078] | 10984 | 0.000 | 0.3004 | No |
| 63 | NTRK3 | neurotrophic receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:8033] | 11108 | 0.000 | 0.2971 | No |
| 64 | CNTF | ciliary neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:2169] | 12497 | 0.000 | 0.2595 | No |
| 65 | SP6 | Sp6 transcription factor [Source:HGNC Symbol;Acc:HGNC:14530] | 12524 | 0.000 | 0.2588 | No |
| 66 | MSX1 | msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391] | 12646 | 0.000 | 0.2555 | No |
| 67 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 12936 | 0.000 | 0.2477 | No |
| 68 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 13678 | 0.000 | 0.2277 | No |
| 69 | PLXNB1 | plexin B1 [Source:HGNC Symbol;Acc:HGNC:9103] | 14215 | 0.000 | 0.2132 | No |
| 70 | TLX1 | T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056] | 14467 | 0.000 | 0.2064 | No |
| 71 | PCSK2 | proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744] | 16328 | 0.000 | 0.1560 | No |
| 72 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 16452 | 0.000 | 0.1527 | No |
| 73 | IL2 | interleukin 2 [Source:HGNC Symbol;Acc:HGNC:6001] | 17768 | 0.000 | 0.1171 | No |
| 74 | LPO | lactoperoxidase [Source:HGNC Symbol;Acc:HGNC:6678] | 18715 | 0.000 | 0.0915 | No |
| 75 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 19079 | 0.000 | 0.0817 | No |
| 76 | BNC2 | basonuclin 2 [Source:HGNC Symbol;Acc:HGNC:30988] | 19292 | 0.000 | 0.0760 | No |
| 77 | NR2F2 | nuclear receptor subfamily 2 group F member 2 [Source:HGNC Symbol;Acc:HGNC:7976] | 19584 | 0.000 | 0.0681 | No |
| 78 | ZNF532 | zinc finger protein 532 [Source:HGNC Symbol;Acc:HGNC:30940] | 21958 | 0.000 | 0.0039 | No |
| 79 | CD70 | CD70 molecule [Source:HGNC Symbol;Acc:HGNC:11937] | 23221 | 0.000 | -0.0303 | No |
| 80 | C1QL1 | complement C1q like 1 [Source:HGNC Symbol;Acc:HGNC:24182] | 23436 | 0.000 | -0.0361 | No |
| 81 | FOXS1 | forkhead box S1 [Source:HGNC Symbol;Acc:HGNC:3735] | 23640 | 0.000 | -0.0416 | No |
| 82 | SLC25A18 | solute carrier family 25 member 18 [Source:HGNC Symbol;Acc:HGNC:10988] | 23767 | 0.000 | -0.0450 | No |
| 83 | LAMA1 | laminin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6481] | 23932 | 0.000 | -0.0494 | No |
| 84 | NRGN | neurogranin [Source:HGNC Symbol;Acc:HGNC:8000] | 24367 | 0.000 | -0.0611 | No |
| 85 | FTHL17 | ferritin heavy chain like 17 [Source:HGNC Symbol;Acc:HGNC:3987] | 24622 | 0.000 | -0.0680 | No |
| 86 | FGF1 | fibroblast growth factor 1 [Source:HGNC Symbol;Acc:HGNC:3665] | 25662 | 0.000 | -0.0961 | No |
| 87 | SOX5 | SRY-box transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:11201] | 26411 | 0.000 | -0.1164 | No |
| 88 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 28229 | -0.068 | -0.1650 | No |
| 89 | STAT6 | signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368] | 28266 | -0.073 | -0.1654 | No |
| 90 | PPP2R5E | protein phosphatase 2 regulatory subunit B'epsilon [Source:HGNC Symbol;Acc:HGNC:9313] | 28527 | -0.106 | -0.1716 | No |
| 91 | RASSF2 | Ras association domain family member 2 [Source:HGNC Symbol;Acc:HGNC:9883] | 28790 | -0.143 | -0.1776 | No |
| 92 | TNKS1BP1 | tankyrase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19081] | 29211 | -0.202 | -0.1873 | No |
| 93 | CCR10 | C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474] | 29525 | -0.245 | -0.1939 | No |
| 94 | GEM | GTP binding protein overexpressed in skeletal muscle [Source:HGNC Symbol;Acc:HGNC:4234] | 29835 | -0.294 | -0.1999 | No |
| 95 | ARID1A | AT-rich interaction domain 1A [Source:HGNC Symbol;Acc:HGNC:11110] | 30413 | -0.370 | -0.2126 | No |
| 96 | BMP2K | BMP2 inducible kinase [Source:HGNC Symbol;Acc:HGNC:18041] | 30493 | -0.382 | -0.2117 | No |
| 97 | SH3KBP1 | SH3 domain containing kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13867] | 30613 | -0.404 | -0.2118 | No |
| 98 | TCEA2 | transcription elongation factor A2 [Source:HGNC Symbol;Acc:HGNC:11614] | 30759 | -0.426 | -0.2123 | No |
| 99 | ENO3 | enolase 3 [Source:HGNC Symbol;Acc:HGNC:3354] | 31272 | -0.506 | -0.2222 | No |
| 100 | PSME3IP1 | proteasome activator subunit 3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29856] | 31627 | -0.566 | -0.2273 | No |
| 101 | CREB1 | cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345] | 31635 | -0.567 | -0.2231 | No |
| 102 | NFAT5 | nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774] | 32010 | -0.643 | -0.2281 | No |
| 103 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 32767 | -0.816 | -0.2422 | No |
| 104 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 32821 | -0.827 | -0.2371 | No |
| 105 | UBE2H | ubiquitin conjugating enzyme E2 H [Source:HGNC Symbol;Acc:HGNC:12484] | 32853 | -0.836 | -0.2313 | No |
| 106 | CHD6 | chromodomain helicase DNA binding protein 6 [Source:HGNC Symbol;Acc:HGNC:19057] | 32922 | -0.853 | -0.2265 | No |
| 107 | MIDEAS | mitotic deacetylase associated SANT domain protein [Source:HGNC Symbol;Acc:HGNC:19853] | 33237 | -0.943 | -0.2275 | No |
| 108 | ALG6 | ALG6 alpha-1,3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23157] | 33354 | -0.973 | -0.2230 | No |
| 109 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 33366 | -0.976 | -0.2156 | No |
| 110 | PNKD | PNKD metallo-beta-lactamase domain containing [Source:HGNC Symbol;Acc:HGNC:9153] | 33670 | -1.071 | -0.2154 | No |
| 111 | PKN1 | protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405] | 33776 | -1.103 | -0.2095 | No |
| 112 | SLC6A12 | solute carrier family 6 member 12 [Source:HGNC Symbol;Acc:HGNC:11045] | 33870 | -1.135 | -0.2031 | No |
| 113 | RPS6KA4 | ribosomal protein S6 kinase A4 [Source:HGNC Symbol;Acc:HGNC:10433] | 33906 | -1.153 | -0.1950 | No |
| 114 | STX4 | syntaxin 4 [Source:HGNC Symbol;Acc:HGNC:11439] | 33908 | -1.153 | -0.1859 | No |
| 115 | KAT7 | lysine acetyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:17016] | 33997 | -1.185 | -0.1790 | No |
| 116 | TP53 | tumor protein p53 [Source:HGNC Symbol;Acc:HGNC:11998] | 34112 | -1.214 | -0.1725 | No |
| 117 | CNTNAP1 | contactin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:8011] | 34205 | -1.247 | -0.1652 | No |
| 118 | RELB | RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] | 34378 | -1.310 | -0.1595 | No |
| 119 | CCDC107 | coiled-coil domain containing 107 [Source:HGNC Symbol;Acc:HGNC:28465] | 34388 | -1.315 | -0.1494 | No |
| 120 | HOXA4 | homeobox A4 [Source:HGNC Symbol;Acc:HGNC:5105] | 34441 | -1.332 | -0.1403 | No |
| 121 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 34562 | -1.376 | -0.1327 | No |
| 122 | ENKD1 | enkurin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25246] | 34624 | -1.401 | -0.1233 | No |
| 123 | SLC44A1 | solute carrier family 44 member 1 [Source:HGNC Symbol;Acc:HGNC:18798] | 34628 | -1.402 | -0.1124 | No |
| 124 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 35074 | -1.612 | -0.1117 | No |
| 125 | CYLD | CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584] | 35113 | -1.633 | -0.0999 | No |
| 126 | JAK3 | Janus kinase 3 [Source:HGNC Symbol;Acc:HGNC:6193] | 35209 | -1.679 | -0.0892 | No |
| 127 | CALCOCO1 | calcium binding and coiled-coil domain 1 [Source:HGNC Symbol;Acc:HGNC:29306] | 35218 | -1.684 | -0.0762 | No |
| 128 | TOM1L1 | target of myb1 like 1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11983] | 35556 | -1.870 | -0.0706 | No |
| 129 | HIVEP1 | HIVEP zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:4920] | 35977 | -2.194 | -0.0647 | No |
| 130 | LIX1L | limb and CNS expressed 1 like [Source:HGNC Symbol;Acc:HGNC:28715] | 35989 | -2.198 | -0.0477 | No |
| 131 | TRIM47 | tripartite motif containing 47 [Source:HGNC Symbol;Acc:HGNC:19020] | 36010 | -2.210 | -0.0308 | No |
| 132 | FAM117A | family with sequence similarity 117 member A [Source:HGNC Symbol;Acc:HGNC:24179] | 36047 | -2.239 | -0.0141 | No |
| 133 | S1PR2 | sphingosine-1-phosphate receptor 2 [Source:HGNC Symbol;Acc:HGNC:3169] | 36182 | -2.351 | 0.0007 | No |
| 134 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 36686 | -3.021 | 0.0109 | No |
