Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | MIR4689 |
| Enrichment Score (ES) | -0.6656433 |
| Normalized Enrichment Score (NES) | -1.4026226 |
| Nominal p-value | 0.012731481 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | BCAT1 | branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976] | 277 | 2.648 | 0.0336 | No |
| 2 | SLC35F1 | solute carrier family 35 member F1 [Source:HGNC Symbol;Acc:HGNC:21483] | 1565 | 1.131 | 0.0164 | No |
| 3 | TOP1 | DNA topoisomerase I [Source:HGNC Symbol;Acc:HGNC:11986] | 1606 | 1.107 | 0.0325 | No |
| 4 | NR6A1 | nuclear receptor subfamily 6 group A member 1 [Source:HGNC Symbol;Acc:HGNC:7985] | 2221 | 0.855 | 0.0292 | No |
| 5 | SCAF4 | SR-related CTD associated factor 4 [Source:HGNC Symbol;Acc:HGNC:19304] | 2234 | 0.850 | 0.0420 | No |
| 6 | SOCS6 | suppressor of cytokine signaling 6 [Source:HGNC Symbol;Acc:HGNC:16833] | 2903 | 0.652 | 0.0341 | No |
| 7 | IL13RA1 | interleukin 13 receptor subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:5974] | 3103 | 0.607 | 0.0382 | No |
| 8 | ZDHHC6 | zinc finger DHHC-type palmitoyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:19160] | 3269 | 0.567 | 0.0425 | No |
| 9 | ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29642] | 3648 | 0.483 | 0.0398 | No |
| 10 | FMNL3 | formin like 3 [Source:HGNC Symbol;Acc:HGNC:23698] | 3919 | 0.432 | 0.0392 | No |
| 11 | BLMH | bleomycin hydrolase [Source:HGNC Symbol;Acc:HGNC:1059] | 4293 | 0.363 | 0.0347 | No |
| 12 | CPSF7 | cleavage and polyadenylation specific factor 7 [Source:HGNC Symbol;Acc:HGNC:30098] | 4800 | 0.278 | 0.0254 | No |
| 13 | WNT1 | Wnt family member 1 [Source:HGNC Symbol;Acc:HGNC:12774] | 5046 | 0.234 | 0.0224 | No |
| 14 | ZNF99 | zinc finger protein 99 [Source:HGNC Symbol;Acc:HGNC:13175] | 5398 | 0.177 | 0.0156 | No |
| 15 | LUZP1 | leucine zipper protein 1 [Source:HGNC Symbol;Acc:HGNC:14985] | 5425 | 0.172 | 0.0176 | No |
| 16 | NOL4L | nucleolar protein 4 like [Source:HGNC Symbol;Acc:HGNC:16106] | 5998 | 0.089 | 0.0035 | No |
| 17 | LEPROT | leptin receptor overlapping transcript [Source:HGNC Symbol;Acc:HGNC:29477] | 6189 | 0.062 | -0.0006 | No |
| 18 | IGF2R | insulin like growth factor 2 receptor [Source:HGNC Symbol;Acc:HGNC:5467] | 6250 | 0.051 | -0.0015 | No |
| 19 | ZBTB39 | zinc finger and BTB domain containing 39 [Source:HGNC Symbol;Acc:HGNC:29014] | 6276 | 0.045 | -0.0014 | No |
| 20 | BAZ2A | bromodomain adjacent to zinc finger domain 2A [Source:HGNC Symbol;Acc:HGNC:962] | 6480 | 0.016 | -0.0067 | No |
| 21 | RNASE2 | ribonuclease A family member 2 [Source:HGNC Symbol;Acc:HGNC:10045] | 7456 | 0.000 | -0.0330 | No |
| 22 | UBE2QL1 | ubiquitin conjugating enzyme E2 Q family like 1 [Source:HGNC Symbol;Acc:HGNC:37269] | 7779 | 0.000 | -0.0417 | No |
| 23 | POU3F3 | POU class 3 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:9216] | 8408 | 0.000 | -0.0587 | No |
| 24 | MAP7D3 | MAP7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25742] | 8410 | 0.000 | -0.0587 | No |
| 25 | SH3TC2 | SH3 domain and tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:29427] | 8981 | 0.000 | -0.0741 | No |
| 26 | GRIN2A | glutamate ionotropic receptor NMDA type subunit 2A [Source:HGNC Symbol;Acc:HGNC:4585] | 10500 | 0.000 | -0.1152 | No |
| 27 | RIMBP2 | RIMS binding protein 2 [Source:HGNC Symbol;Acc:HGNC:30339] | 10546 | 0.000 | -0.1164 | No |
| 28 | RTL5 | retrotransposon Gag like 5 [Source:HGNC Symbol;Acc:HGNC:29430] | 10647 | 0.000 | -0.1191 | No |
| 29 | GFRA1 | GDNF family receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4243] | 11384 | 0.000 | -0.1390 | No |
| 30 | GSDMC | gasdermin C [Source:HGNC Symbol;Acc:HGNC:7151] | 13330 | 0.000 | -0.1915 | No |
| 31 | GDF5 | growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220] | 13559 | 0.000 | -0.1977 | No |
| 32 | KIAA1549L | KIAA1549 like [Source:HGNC Symbol;Acc:HGNC:24836] | 13834 | 0.000 | -0.2051 | No |
| 33 | SLC34A1 | solute carrier family 34 member 1 [Source:HGNC Symbol;Acc:HGNC:11019] | 16312 | 0.000 | -0.2720 | No |
| 34 | SEMA7A | semaphorin 7A (John Milton Hagen blood group) [Source:HGNC Symbol;Acc:HGNC:10741] | 17888 | 0.000 | -0.3146 | No |
| 35 | TBR1 | T-box brain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11590] | 19676 | 0.000 | -0.3629 | No |
| 36 | GABRB2 | gamma-aminobutyric acid type A receptor subunit beta2 [Source:HGNC Symbol;Acc:HGNC:4082] | 19953 | 0.000 | -0.3703 | No |
| 37 | GABRA6 | gamma-aminobutyric acid type A receptor subunit alpha6 [Source:HGNC Symbol;Acc:HGNC:4080] | 19997 | 0.000 | -0.3715 | No |
| 38 | IGSF5 | immunoglobulin superfamily member 5 [Source:HGNC Symbol;Acc:HGNC:5952] | 20689 | 0.000 | -0.3902 | No |
| 39 | VWC2 | von Willebrand factor C domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30200] | 21284 | 0.000 | -0.4062 | No |
| 40 | KRT40 | keratin 40 [Source:HGNC Symbol;Acc:HGNC:26707] | 22143 | 0.000 | -0.4294 | No |
| 41 | SLAMF7 | SLAM family member 7 [Source:HGNC Symbol;Acc:HGNC:21394] | 23131 | 0.000 | -0.4561 | No |
| 42 | CD59 | CD59 molecule (CD59 blood group) [Source:HGNC Symbol;Acc:HGNC:1689] | 23211 | 0.000 | -0.4582 | No |
| 43 | CD84 | CD84 molecule [Source:HGNC Symbol;Acc:HGNC:1704] | 23241 | 0.000 | -0.4590 | No |
| 44 | ADCYAP1R1 | ADCYAP receptor type I [Source:HGNC Symbol;Acc:HGNC:242] | 24466 | 0.000 | -0.4921 | No |
| 45 | SNPH | syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931] | 26104 | 0.000 | -0.5363 | No |
| 46 | CCDC149 | coiled-coil domain containing 149 [Source:HGNC Symbol;Acc:HGNC:25405] | 26206 | 0.000 | -0.5391 | No |
| 47 | CCDC178 | coiled-coil domain containing 178 [Source:HGNC Symbol;Acc:HGNC:29588] | 26254 | 0.000 | -0.5403 | No |
| 48 | AL162231.1 | uncharacterized LOC730098 [Source:NCBI gene (formerly Entrezgene);Acc:730098] | 27353 | 0.000 | -0.5700 | No |
| 49 | IPO5 | importin 5 [Source:HGNC Symbol;Acc:HGNC:6402] | 28001 | -0.032 | -0.5870 | No |
| 50 | CCDC127 | coiled-coil domain containing 127 [Source:HGNC Symbol;Acc:HGNC:30520] | 28013 | -0.033 | -0.5868 | No |
| 51 | ENDOD1 | endonuclease domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29129] | 28076 | -0.043 | -0.5878 | No |
| 52 | ATP12A | ATPase H+/K+ transporting non-gastric alpha2 subunit [Source:HGNC Symbol;Acc:HGNC:13816] | 28322 | -0.080 | -0.5932 | No |
| 53 | MIER1 | MIER1 transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:29657] | 28777 | -0.141 | -0.6032 | No |
| 54 | CNGA3 | cyclic nucleotide gated channel subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:2150] | 29186 | -0.199 | -0.6112 | No |
| 55 | BRPF3 | bromodomain and PHD finger containing 3 [Source:HGNC Symbol;Acc:HGNC:14256] | 29203 | -0.201 | -0.6085 | No |
| 56 | TMCO1 | transmembrane and coiled-coil domains 1 [Source:HGNC Symbol;Acc:HGNC:18188] | 29737 | -0.279 | -0.6186 | No |
| 57 | TROAP | trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327] | 30395 | -0.368 | -0.6306 | No |
| 58 | AMOTL2 | angiomotin like 2 [Source:HGNC Symbol;Acc:HGNC:17812] | 30410 | -0.370 | -0.6253 | No |
| 59 | EXOC8 | exocyst complex component 8 [Source:HGNC Symbol;Acc:HGNC:24659] | 30690 | -0.416 | -0.6263 | No |
| 60 | PKD2L2 | polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012] | 30904 | -0.449 | -0.6251 | No |
| 61 | ING3 | inhibitor of growth family member 3 [Source:HGNC Symbol;Acc:HGNC:14587] | 31651 | -0.569 | -0.6365 | No |
| 62 | SLF2 | SMC5-SMC6 complex localization factor 2 [Source:HGNC Symbol;Acc:HGNC:17814] | 32732 | -0.806 | -0.6531 | Yes |
| 63 | VRK3 | VRK serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:18996] | 33028 | -0.880 | -0.6474 | Yes |
| 64 | ABRAXAS1 | abraxas 1, BRCA1 A complex subunit [Source:HGNC Symbol;Acc:HGNC:25829] | 33502 | -1.020 | -0.6444 | Yes |
| 65 | GPR65 | G protein-coupled receptor 65 [Source:HGNC Symbol;Acc:HGNC:4517] | 33575 | -1.041 | -0.6302 | Yes |
| 66 | CEP120 | centrosomal protein 120 [Source:HGNC Symbol;Acc:HGNC:26690] | 33739 | -1.089 | -0.6177 | Yes |
| 67 | KAT7 | lysine acetyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:17016] | 33997 | -1.185 | -0.6062 | Yes |
| 68 | ZNF280D | zinc finger protein 280D [Source:HGNC Symbol;Acc:HGNC:25953] | 34014 | -1.189 | -0.5882 | Yes |
| 69 | SV2A | synaptic vesicle glycoprotein 2A [Source:HGNC Symbol;Acc:HGNC:20566] | 34152 | -1.226 | -0.5729 | Yes |
| 70 | NRN1 | neuritin 1 [Source:HGNC Symbol;Acc:HGNC:17972] | 34308 | -1.283 | -0.5572 | Yes |
| 71 | HPSE | heparanase [Source:HGNC Symbol;Acc:HGNC:5164] | 34568 | -1.379 | -0.5428 | Yes |
| 72 | CIT | citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985] | 34904 | -1.517 | -0.5283 | Yes |
| 73 | KLHL24 | kelch like family member 24 [Source:HGNC Symbol;Acc:HGNC:25947] | 34968 | -1.552 | -0.5059 | Yes |
| 74 | FOXJ2 | forkhead box J2 [Source:HGNC Symbol;Acc:HGNC:24818] | 34990 | -1.562 | -0.4822 | Yes |
| 75 | EYA4 | EYA transcriptional coactivator and phosphatase 4 [Source:HGNC Symbol;Acc:HGNC:3522] | 35124 | -1.638 | -0.4604 | Yes |
| 76 | ESYT1 | extended synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:29534] | 35345 | -1.751 | -0.4391 | Yes |
| 77 | GRSF1 | G-rich RNA sequence binding factor 1 [Source:HGNC Symbol;Acc:HGNC:4610] | 35368 | -1.762 | -0.4124 | Yes |
| 78 | FAM167B | family with sequence similarity 167 member B [Source:HGNC Symbol;Acc:HGNC:28133] | 35422 | -1.788 | -0.3861 | Yes |
| 79 | FAM53B | family with sequence similarity 53 member B [Source:HGNC Symbol;Acc:HGNC:28968] | 35538 | -1.861 | -0.3603 | Yes |
| 80 | S1PR1 | sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165] | 36026 | -2.225 | -0.3389 | Yes |
| 81 | MBP | myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925] | 36104 | -2.280 | -0.3056 | Yes |
| 82 | ZNF652 | zinc finger protein 652 [Source:HGNC Symbol;Acc:HGNC:29147] | 36308 | -2.479 | -0.2726 | Yes |
| 83 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36326 | -2.499 | -0.2343 | Yes |
| 84 | HBP1 | HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200] | 36337 | -2.510 | -0.1956 | Yes |
| 85 | FAM168A | family with sequence similarity 168 member A [Source:HGNC Symbol;Acc:HGNC:28999] | 36540 | -2.784 | -0.1579 | Yes |
| 86 | ARHGEF39 | Rho guanine nucleotide exchange factor 39 [Source:HGNC Symbol;Acc:HGNC:25909] | 36626 | -2.912 | -0.1150 | Yes |
| 87 | PRKRA | protein activator of interferon induced protein kinase EIF2AK2 [Source:HGNC Symbol;Acc:HGNC:9438] | 36912 | -3.603 | -0.0667 | Yes |
| 88 | KANK2 | KN motif and ankyrin repeat domains 2 [Source:HGNC Symbol;Acc:HGNC:29300] | 37077 | -4.608 | 0.0004 | Yes |
