Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_CCNA2 |
| Enrichment Score (ES) | -0.8622028 |
| Normalized Enrichment Score (NES) | -1.7554741 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1504 | 1.154 | -0.0314 | No |
| 2 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 24301 | 0.000 | -0.6471 | No |
| 3 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26430 | 0.000 | -0.7046 | No |
| 4 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27912 | -0.021 | -0.7444 | No |
| 5 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 30352 | -0.363 | -0.8074 | No |
| 6 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 30452 | -0.375 | -0.8071 | No |
| 7 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 32199 | -0.682 | -0.8488 | No |
| 8 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 32625 | -0.776 | -0.8541 | Yes |
| 9 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32700 | -0.796 | -0.8497 | Yes |
| 10 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 32783 | -0.819 | -0.8454 | Yes |
| 11 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33267 | -0.949 | -0.8508 | Yes |
| 12 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33690 | -1.077 | -0.8536 | Yes |
| 13 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33713 | -1.082 | -0.8455 | Yes |
| 14 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33721 | -1.084 | -0.8371 | Yes |
| 15 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 33771 | -1.101 | -0.8296 | Yes |
| 16 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34522 | -1.361 | -0.8389 | Yes |
| 17 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34533 | -1.364 | -0.8283 | Yes |
| 18 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34655 | -1.411 | -0.8203 | Yes |
| 19 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34665 | -1.416 | -0.8092 | Yes |
| 20 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34860 | -1.492 | -0.8025 | Yes |
| 21 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 34894 | -1.508 | -0.7913 | Yes |
| 22 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34896 | -1.510 | -0.7793 | Yes |
| 23 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35012 | -1.573 | -0.7698 | Yes |
| 24 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35165 | -1.659 | -0.7606 | Yes |
| 25 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35266 | -1.714 | -0.7496 | Yes |
| 26 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35303 | -1.732 | -0.7368 | Yes |
| 27 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35315 | -1.737 | -0.7232 | Yes |
| 28 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35455 | -1.811 | -0.7124 | Yes |
| 29 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35493 | -1.831 | -0.6988 | Yes |
| 30 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35508 | -1.842 | -0.6844 | Yes |
| 31 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35527 | -1.854 | -0.6701 | Yes |
| 32 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35530 | -1.855 | -0.6553 | Yes |
| 33 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35572 | -1.882 | -0.6413 | Yes |
| 34 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35645 | -1.933 | -0.6278 | Yes |
| 35 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35723 | -1.996 | -0.6139 | Yes |
| 36 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35732 | -2.004 | -0.5981 | Yes |
| 37 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35793 | -2.055 | -0.5833 | Yes |
| 38 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35889 | -2.122 | -0.5689 | Yes |
| 39 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35912 | -2.142 | -0.5524 | Yes |
| 40 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35922 | -2.150 | -0.5354 | Yes |
| 41 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35930 | -2.153 | -0.5184 | Yes |
| 42 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35935 | -2.155 | -0.5013 | Yes |
| 43 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.4844 | Yes |
| 44 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35963 | -2.182 | -0.4671 | Yes |
| 45 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35968 | -2.186 | -0.4497 | Yes |
| 46 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36012 | -2.211 | -0.4332 | Yes |
| 47 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36015 | -2.212 | -0.4155 | Yes |
| 48 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36024 | -2.225 | -0.3980 | Yes |
| 49 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36049 | -2.239 | -0.3807 | Yes |
| 50 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.3634 | Yes |
| 51 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36232 | -2.394 | -0.3483 | Yes |
| 52 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36238 | -2.399 | -0.3293 | Yes |
| 53 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36286 | -2.451 | -0.3109 | Yes |
| 54 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36289 | -2.458 | -0.2913 | Yes |
| 55 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36301 | -2.470 | -0.2719 | Yes |
| 56 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36326 | -2.499 | -0.2525 | Yes |
| 57 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36438 | -2.629 | -0.2345 | Yes |
| 58 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36458 | -2.656 | -0.2138 | Yes |
| 59 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36470 | -2.674 | -0.1927 | Yes |
| 60 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36519 | -2.751 | -0.1720 | Yes |
| 61 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36546 | -2.789 | -0.1504 | Yes |
| 62 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36555 | -2.800 | -0.1282 | Yes |
| 63 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36562 | -2.813 | -0.1059 | Yes |
| 64 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36620 | -2.903 | -0.0842 | Yes |
| 65 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36622 | -2.908 | -0.0610 | Yes |
| 66 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36679 | -3.000 | -0.0385 | Yes |
| 67 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36696 | -3.045 | -0.0146 | Yes |
| 68 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36747 | -3.148 | 0.0093 | Yes |
