Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_CDC20 |
| Enrichment Score (ES) | -0.8384823 |
| Normalized Enrichment Score (NES) | -1.6873327 |
| Nominal p-value | 0.0 |
| FDR q-value | 5.8046216E-4 |
| FWER p-Value | 0.004 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | UBE2S | ubiquitin conjugating enzyme E2 S [Source:HGNC Symbol;Acc:HGNC:17895] | 1258 | 1.294 | -0.0210 | No |
| 2 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1504 | 1.154 | -0.0160 | No |
| 3 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 2617 | 0.727 | -0.0387 | No |
| 4 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26430 | 0.000 | -0.6817 | No |
| 5 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27912 | -0.021 | -0.7215 | No |
| 6 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 28646 | -0.123 | -0.7400 | No |
| 7 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 32199 | -0.682 | -0.8291 | Yes |
| 8 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 32214 | -0.686 | -0.8226 | Yes |
| 9 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 32625 | -0.776 | -0.8258 | Yes |
| 10 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32700 | -0.796 | -0.8198 | Yes |
| 11 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 32783 | -0.819 | -0.8138 | Yes |
| 12 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 33697 | -1.078 | -0.8277 | Yes |
| 13 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33713 | -1.082 | -0.8172 | Yes |
| 14 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33721 | -1.084 | -0.8065 | Yes |
| 15 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 33771 | -1.101 | -0.7968 | Yes |
| 16 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34533 | -1.364 | -0.8036 | Yes |
| 17 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34655 | -1.411 | -0.7927 | Yes |
| 18 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 34826 | -1.475 | -0.7825 | Yes |
| 19 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34860 | -1.492 | -0.7684 | Yes |
| 20 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 34894 | -1.508 | -0.7541 | Yes |
| 21 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34896 | -1.510 | -0.7390 | Yes |
| 22 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35165 | -1.659 | -0.7296 | Yes |
| 23 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 35207 | -1.677 | -0.7138 | Yes |
| 24 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35266 | -1.714 | -0.6982 | Yes |
| 25 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35315 | -1.737 | -0.6820 | Yes |
| 26 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35455 | -1.811 | -0.6676 | Yes |
| 27 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35493 | -1.831 | -0.6502 | Yes |
| 28 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35527 | -1.854 | -0.6325 | Yes |
| 29 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35530 | -1.855 | -0.6139 | Yes |
| 30 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35572 | -1.882 | -0.5961 | Yes |
| 31 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35645 | -1.933 | -0.5786 | Yes |
| 32 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35723 | -1.996 | -0.5607 | Yes |
| 33 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35793 | -2.055 | -0.5419 | Yes |
| 34 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35889 | -2.122 | -0.5232 | Yes |
| 35 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35912 | -2.142 | -0.5022 | Yes |
| 36 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35930 | -2.153 | -0.4811 | Yes |
| 37 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35935 | -2.155 | -0.4595 | Yes |
| 38 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.4383 | Yes |
| 39 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35968 | -2.186 | -0.4165 | Yes |
| 40 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36049 | -2.239 | -0.3962 | Yes |
| 41 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36062 | -2.250 | -0.3739 | Yes |
| 42 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.3517 | Yes |
| 43 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36232 | -2.394 | -0.3317 | Yes |
| 44 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36249 | -2.411 | -0.3079 | Yes |
| 45 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36286 | -2.451 | -0.2843 | Yes |
| 46 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36289 | -2.458 | -0.2596 | Yes |
| 47 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36301 | -2.470 | -0.2351 | Yes |
| 48 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36326 | -2.499 | -0.2107 | Yes |
| 49 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36438 | -2.629 | -0.1873 | Yes |
| 50 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36470 | -2.674 | -0.1613 | Yes |
| 51 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36555 | -2.800 | -0.1354 | Yes |
| 52 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36562 | -2.813 | -0.1073 | Yes |
| 53 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36620 | -2.903 | -0.0797 | Yes |
| 54 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36679 | -3.000 | -0.0511 | Yes |
| 55 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36696 | -3.045 | -0.0210 | Yes |
| 56 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36747 | -3.148 | 0.0093 | Yes |
