Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_ESPL1 |
| Enrichment Score (ES) | -0.8976627 |
| Normalized Enrichment Score (NES) | -1.6948484 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.706933E-4 |
| FWER p-Value | 0.004 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 24301 | 0.000 | -0.6558 | No |
| 2 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 32783 | -0.819 | -0.8726 | No |
| 3 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33713 | -1.082 | -0.8817 | Yes |
| 4 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33721 | -1.084 | -0.8659 | Yes |
| 5 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 33771 | -1.101 | -0.8510 | Yes |
| 6 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 33947 | -1.167 | -0.8386 | Yes |
| 7 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34533 | -1.364 | -0.8343 | Yes |
| 8 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34655 | -1.411 | -0.8168 | Yes |
| 9 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 34826 | -1.475 | -0.7996 | Yes |
| 10 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34860 | -1.492 | -0.7785 | Yes |
| 11 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35165 | -1.659 | -0.7623 | Yes |
| 12 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 35207 | -1.677 | -0.7387 | Yes |
| 13 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35266 | -1.714 | -0.7150 | Yes |
| 14 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35303 | -1.732 | -0.6905 | Yes |
| 15 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35315 | -1.737 | -0.6652 | Yes |
| 16 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35493 | -1.831 | -0.6430 | Yes |
| 17 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35645 | -1.933 | -0.6186 | Yes |
| 18 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35723 | -1.996 | -0.5912 | Yes |
| 19 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35889 | -2.122 | -0.5644 | Yes |
| 20 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35930 | -2.153 | -0.5338 | Yes |
| 21 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35935 | -2.155 | -0.5022 | Yes |
| 22 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.4707 | Yes |
| 23 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36012 | -2.211 | -0.4395 | Yes |
| 24 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.4080 | Yes |
| 25 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36232 | -2.394 | -0.3768 | Yes |
| 26 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36249 | -2.411 | -0.3417 | Yes |
| 27 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36286 | -2.451 | -0.3066 | Yes |
| 28 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36289 | -2.458 | -0.2704 | Yes |
| 29 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 36383 | -2.566 | -0.2351 | Yes |
| 30 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36438 | -2.629 | -0.1979 | Yes |
| 31 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36467 | -2.673 | -0.1592 | Yes |
| 32 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36519 | -2.751 | -0.1201 | Yes |
| 33 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36679 | -3.000 | -0.0802 | Yes |
| 34 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36696 | -3.045 | -0.0358 | Yes |
| 35 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36747 | -3.148 | 0.0093 | Yes |
