Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_FEN1 |
| Enrichment Score (ES) | -0.8103012 |
| Normalized Enrichment Score (NES) | -1.6203287 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0027361575 |
| FWER p-Value | 0.052 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAR1 | GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14264] | 685 | 1.818 | 0.0008 | No |
| 2 | DKC1 | dyskerin pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:2890] | 1131 | 1.374 | 0.0033 | No |
| 3 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1504 | 1.154 | 0.0055 | No |
| 4 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2049 | 0.918 | 0.0005 | No |
| 5 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 4894 | 0.258 | -0.0736 | No |
| 6 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 4956 | 0.250 | -0.0726 | No |
| 7 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 5239 | 0.202 | -0.0780 | No |
| 8 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26430 | 0.000 | -0.6502 | No |
| 9 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27912 | -0.021 | -0.6900 | No |
| 10 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 27938 | -0.026 | -0.6904 | No |
| 11 | COPS3 | COP9 signalosome subunit 3 [Source:HGNC Symbol;Acc:HGNC:2239] | 30231 | -0.345 | -0.7486 | No |
| 12 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 30452 | -0.375 | -0.7506 | No |
| 13 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 32450 | -0.733 | -0.7967 | No |
| 14 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32700 | -0.796 | -0.7950 | No |
| 15 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33267 | -0.949 | -0.8002 | Yes |
| 16 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 33618 | -1.054 | -0.7985 | Yes |
| 17 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 33697 | -1.078 | -0.7892 | Yes |
| 18 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33721 | -1.084 | -0.7784 | Yes |
| 19 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 33914 | -1.155 | -0.7713 | Yes |
| 20 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 34454 | -1.336 | -0.7717 | Yes |
| 21 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34522 | -1.361 | -0.7591 | Yes |
| 22 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 34584 | -1.386 | -0.7461 | Yes |
| 23 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34655 | -1.411 | -0.7330 | Yes |
| 24 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34665 | -1.416 | -0.7183 | Yes |
| 25 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 34894 | -1.508 | -0.7085 | Yes |
| 26 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34896 | -1.510 | -0.6925 | Yes |
| 27 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35012 | -1.573 | -0.6790 | Yes |
| 28 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35131 | -1.642 | -0.6647 | Yes |
| 29 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35455 | -1.811 | -0.6543 | Yes |
| 30 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35527 | -1.854 | -0.6366 | Yes |
| 31 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35530 | -1.855 | -0.6170 | Yes |
| 32 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 35534 | -1.859 | -0.5974 | Yes |
| 33 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35572 | -1.882 | -0.5784 | Yes |
| 34 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35723 | -1.996 | -0.5614 | Yes |
| 35 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35755 | -2.023 | -0.5408 | Yes |
| 36 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 35868 | -2.107 | -0.5215 | Yes |
| 37 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35912 | -2.142 | -0.4999 | Yes |
| 38 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35922 | -2.150 | -0.4774 | Yes |
| 39 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35930 | -2.153 | -0.4548 | Yes |
| 40 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.4325 | Yes |
| 41 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35968 | -2.186 | -0.4095 | Yes |
| 42 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36015 | -2.212 | -0.3873 | Yes |
| 43 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36049 | -2.239 | -0.3645 | Yes |
| 44 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.3414 | Yes |
| 45 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36232 | -2.394 | -0.3201 | Yes |
| 46 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36301 | -2.470 | -0.2958 | Yes |
| 47 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36326 | -2.499 | -0.2700 | Yes |
| 48 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36458 | -2.656 | -0.2454 | Yes |
| 49 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 36505 | -2.720 | -0.2178 | Yes |
| 50 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36546 | -2.789 | -0.1894 | Yes |
| 51 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36555 | -2.800 | -0.1599 | Yes |
| 52 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36620 | -2.903 | -0.1309 | Yes |
| 53 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36622 | -2.908 | -0.1001 | Yes |
| 54 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36696 | -3.045 | -0.0699 | Yes |
| 55 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36872 | -3.490 | -0.0376 | Yes |
| 56 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 37024 | -4.108 | 0.0018 | Yes |
