Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GNF2_RRM1 |
| Enrichment Score (ES) | -0.78765154 |
| Normalized Enrichment Score (NES) | -1.6528959 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.001158713 |
| FWER p-Value | 0.016 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCT6A | chaperonin containing TCP1 subunit 6A [Source:HGNC Symbol;Acc:HGNC:1620] | 1140 | 1.371 | -0.0210 | No |
| 2 | USP14 | ubiquitin specific peptidase 14 [Source:HGNC Symbol;Acc:HGNC:12612] | 1289 | 1.280 | -0.0159 | No |
| 3 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 1435 | 1.187 | -0.0113 | No |
| 4 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265] | 1473 | 1.164 | -0.0040 | No |
| 5 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1504 | 1.154 | 0.0035 | No |
| 6 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2049 | 0.918 | -0.0047 | No |
| 7 | PSMD14 | proteasome 26S subunit, non-ATPase 14 [Source:HGNC Symbol;Acc:HGNC:16889] | 2065 | 0.909 | 0.0014 | No |
| 8 | PTGES3 | prostaglandin E synthase 3 [Source:HGNC Symbol;Acc:HGNC:16049] | 2499 | 0.764 | -0.0048 | No |
| 9 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 2617 | 0.727 | -0.0028 | No |
| 10 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 4894 | 0.258 | -0.0624 | No |
| 11 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 5239 | 0.202 | -0.0703 | No |
| 12 | MRPL35 | mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489] | 5592 | 0.147 | -0.0787 | No |
| 13 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26430 | 0.000 | -0.6419 | No |
| 14 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27912 | -0.021 | -0.6817 | No |
| 15 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 27938 | -0.026 | -0.6822 | No |
| 16 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 27997 | -0.031 | -0.6836 | No |
| 17 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 28115 | -0.049 | -0.6864 | No |
| 18 | NUP37 | nucleoporin 37 [Source:HGNC Symbol;Acc:HGNC:29929] | 28355 | -0.085 | -0.6922 | No |
| 19 | SERBP1 | SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17860] | 28578 | -0.114 | -0.6974 | No |
| 20 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 28974 | -0.167 | -0.7069 | No |
| 21 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30070 | -0.326 | -0.7342 | No |
| 22 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 30452 | -0.375 | -0.7418 | No |
| 23 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 30899 | -0.449 | -0.7506 | No |
| 24 | CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21906] | 30986 | -0.460 | -0.7496 | No |
| 25 | FH | fumarate hydratase [Source:HGNC Symbol;Acc:HGNC:3700] | 32136 | -0.669 | -0.7759 | No |
| 26 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 32199 | -0.682 | -0.7727 | No |
| 27 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 32450 | -0.733 | -0.7742 | No |
| 28 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 32625 | -0.776 | -0.7734 | No |
| 29 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32700 | -0.796 | -0.7697 | No |
| 30 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33267 | -0.949 | -0.7782 | No |
| 31 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 33618 | -1.054 | -0.7801 | Yes |
| 32 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33690 | -1.077 | -0.7743 | Yes |
| 33 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 33697 | -1.078 | -0.7668 | Yes |
| 34 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33721 | -1.084 | -0.7597 | Yes |
| 35 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 33914 | -1.155 | -0.7566 | Yes |
| 36 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 34454 | -1.336 | -0.7616 | Yes |
| 37 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34522 | -1.361 | -0.7537 | Yes |
| 38 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34533 | -1.364 | -0.7442 | Yes |
| 39 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34655 | -1.411 | -0.7374 | Yes |
| 40 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34665 | -1.416 | -0.7275 | Yes |
| 41 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 34894 | -1.508 | -0.7229 | Yes |
| 42 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34896 | -1.510 | -0.7121 | Yes |
| 43 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35012 | -1.573 | -0.7040 | Yes |
| 44 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35131 | -1.642 | -0.6954 | Yes |
| 45 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35165 | -1.659 | -0.6844 | Yes |
| 46 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35266 | -1.714 | -0.6749 | Yes |
| 47 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35315 | -1.737 | -0.6638 | Yes |
| 48 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35455 | -1.811 | -0.6546 | Yes |
| 49 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35493 | -1.831 | -0.6425 | Yes |
| 50 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35508 | -1.842 | -0.6297 | Yes |
| 51 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35527 | -1.854 | -0.6169 | Yes |
| 52 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 35530 | -1.855 | -0.6037 | Yes |
| 53 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35572 | -1.882 | -0.5913 | Yes |
| 54 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35645 | -1.933 | -0.5795 | Yes |
| 55 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35723 | -1.996 | -0.5673 | Yes |
| 56 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35755 | -2.023 | -0.5536 | Yes |
| 57 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35889 | -2.122 | -0.5421 | Yes |
| 58 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35912 | -2.142 | -0.5273 | Yes |
| 59 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35922 | -2.150 | -0.5122 | Yes |
| 60 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 35930 | -2.153 | -0.4970 | Yes |
| 61 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35935 | -2.155 | -0.4817 | Yes |
| 62 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.4667 | Yes |
| 63 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35963 | -2.182 | -0.4512 | Yes |
| 64 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35968 | -2.186 | -0.4357 | Yes |
| 65 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36012 | -2.211 | -0.4210 | Yes |
| 66 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36015 | -2.212 | -0.4053 | Yes |
| 67 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36049 | -2.239 | -0.3901 | Yes |
| 68 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.3748 | Yes |
| 69 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36232 | -2.394 | -0.3617 | Yes |
| 70 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36238 | -2.399 | -0.3447 | Yes |
| 71 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36286 | -2.451 | -0.3285 | Yes |
| 72 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36289 | -2.458 | -0.3109 | Yes |
| 73 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36301 | -2.470 | -0.2936 | Yes |
| 74 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36326 | -2.499 | -0.2763 | Yes |
| 75 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 36383 | -2.566 | -0.2595 | Yes |
| 76 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36458 | -2.656 | -0.2425 | Yes |
| 77 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36467 | -2.673 | -0.2236 | Yes |
| 78 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36470 | -2.674 | -0.2046 | Yes |
| 79 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 36505 | -2.720 | -0.1860 | Yes |
| 80 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36546 | -2.789 | -0.1672 | Yes |
| 81 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36555 | -2.800 | -0.1474 | Yes |
| 82 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36620 | -2.903 | -0.1283 | Yes |
| 83 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36622 | -2.908 | -0.1076 | Yes |
| 84 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36679 | -3.000 | -0.0876 | Yes |
| 85 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36696 | -3.045 | -0.0663 | Yes |
| 86 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36747 | -3.148 | -0.0451 | Yes |
| 87 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36872 | -3.490 | -0.0235 | Yes |
| 88 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 37024 | -4.108 | 0.0018 | Yes |
