Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | GNF2_XRCC5 |
| Enrichment Score (ES) | 0.6103703 |
| Normalized Enrichment Score (NES) | 1.5058287 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.22886361 |
| FWER p-Value | 0.926 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IFRD1 | interferon related developmental regulator 1 [Source:HGNC Symbol;Acc:HGNC:5456] | 453 | 2.152 | 0.0267 | Yes |
| 2 | RARS1 | arginyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:9870] | 589 | 1.937 | 0.0581 | Yes |
| 3 | SFPQ | splicing factor proline and glutamine rich [Source:HGNC Symbol;Acc:HGNC:10774] | 850 | 1.610 | 0.0801 | Yes |
| 4 | CCT3 | chaperonin containing TCP1 subunit 3 [Source:HGNC Symbol;Acc:HGNC:1616] | 879 | 1.575 | 0.1079 | Yes |
| 5 | PSMA4 | proteasome 20S subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:9533] | 1083 | 1.408 | 0.1279 | Yes |
| 6 | DHX15 | DEAH-box helicase 15 [Source:HGNC Symbol;Acc:HGNC:2738] | 1270 | 1.290 | 0.1462 | Yes |
| 7 | PSMC2 | proteasome 26S subunit, ATPase 2 [Source:HGNC Symbol;Acc:HGNC:9548] | 1389 | 1.211 | 0.1649 | Yes |
| 8 | TARDBP | TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571] | 1427 | 1.190 | 0.1854 | Yes |
| 9 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 1435 | 1.187 | 0.2067 | Yes |
| 10 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265] | 1473 | 1.164 | 0.2267 | Yes |
| 11 | PSMD11 | proteasome 26S subunit, non-ATPase 11 [Source:HGNC Symbol;Acc:HGNC:9556] | 1484 | 1.161 | 0.2474 | Yes |
| 12 | MAGOH | mago homolog, exon junction complex subunit [Source:HGNC Symbol;Acc:HGNC:6815] | 1660 | 1.082 | 0.2623 | Yes |
| 13 | SYNCRIP | synaptotagmin binding cytoplasmic RNA interacting protein [Source:HGNC Symbol;Acc:HGNC:16918] | 1680 | 1.074 | 0.2812 | Yes |
| 14 | POMP | proteasome maturation protein [Source:HGNC Symbol;Acc:HGNC:20330] | 1707 | 1.059 | 0.2996 | Yes |
| 15 | HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:HGNC:5033] | 1777 | 1.023 | 0.3163 | Yes |
| 16 | PSMA3 | proteasome 20S subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:9532] | 1794 | 1.018 | 0.3343 | Yes |
| 17 | MMADHC | metabolism of cobalamin associated D [Source:HGNC Symbol;Acc:HGNC:25221] | 1976 | 0.949 | 0.3465 | Yes |
| 18 | PSMD14 | proteasome 26S subunit, non-ATPase 14 [Source:HGNC Symbol;Acc:HGNC:16889] | 2065 | 0.909 | 0.3606 | Yes |
| 19 | GNAI3 | G protein subunit alpha i3 [Source:HGNC Symbol;Acc:HGNC:4387] | 2155 | 0.877 | 0.3740 | Yes |
| 20 | SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide [Source:HGNC Symbol;Acc:HGNC:11160] | 2241 | 0.848 | 0.3871 | Yes |
| 21 | SNRPD2 | small nuclear ribonucleoprotein D2 polypeptide [Source:HGNC Symbol;Acc:HGNC:11159] | 2332 | 0.816 | 0.3994 | Yes |
| 22 | MAPRE1 | microtubule associated protein RP/EB family member 1 [Source:HGNC Symbol;Acc:HGNC:6890] | 2425 | 0.782 | 0.4111 | Yes |
| 23 | ZNF207 | zinc finger protein 207 [Source:HGNC Symbol;Acc:HGNC:12998] | 2476 | 0.773 | 0.4237 | Yes |
| 24 | PTGES3 | prostaglandin E synthase 3 [Source:HGNC Symbol;Acc:HGNC:16049] | 2499 | 0.764 | 0.4369 | Yes |
| 25 | SRSF1 | serine and arginine rich splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:10780] | 2515 | 0.757 | 0.4502 | Yes |
| 26 | TARS1 | threonyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:11572] | 2526 | 0.754 | 0.4636 | Yes |
| 27 | PSMA5 | proteasome 20S subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:9534] | 2581 | 0.738 | 0.4755 | Yes |
| 28 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 2617 | 0.727 | 0.4877 | Yes |
| 29 | PSMB7 | proteasome 20S subunit beta 7 [Source:HGNC Symbol;Acc:HGNC:9544] | 2747 | 0.694 | 0.4967 | Yes |
| 30 | RBMX | RNA binding motif protein X-linked [Source:HGNC Symbol;Acc:HGNC:9910] | 2871 | 0.661 | 0.5054 | Yes |
| 31 | MRPL3 | mitochondrial ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10379] | 2928 | 0.647 | 0.5156 | Yes |
| 32 | SRSF3 | serine and arginine rich splicing factor 3 [Source:HGNC Symbol;Acc:HGNC:10785] | 2984 | 0.635 | 0.5256 | Yes |
| 33 | HNRNPU | heterogeneous nuclear ribonucleoprotein U [Source:HGNC Symbol;Acc:HGNC:5048] | 3055 | 0.618 | 0.5348 | Yes |
| 34 | PRPF40A | pre-mRNA processing factor 40 homolog A [Source:HGNC Symbol;Acc:HGNC:16463] | 3146 | 0.596 | 0.5432 | Yes |
| 35 | PSMA1 | proteasome 20S subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:9530] | 3202 | 0.583 | 0.5523 | Yes |
| 36 | NCL | nucleolin [Source:HGNC Symbol;Acc:HGNC:7667] | 3216 | 0.580 | 0.5624 | Yes |
| 37 | SUMO1 | small ubiquitin like modifier 1 [Source:HGNC Symbol;Acc:HGNC:12502] | 3263 | 0.568 | 0.5714 | Yes |
| 38 | SRP54 | signal recognition particle 54 [Source:HGNC Symbol;Acc:HGNC:11301] | 3272 | 0.566 | 0.5814 | Yes |
| 39 | BANF1 | BAF nuclear assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:17397] | 3452 | 0.524 | 0.5861 | Yes |
| 40 | XRCC5 | X-ray repair cross complementing 5 [Source:HGNC Symbol;Acc:HGNC:12833] | 3799 | 0.453 | 0.5849 | Yes |
| 41 | EIF4A1 | eukaryotic translation initiation factor 4A1 [Source:HGNC Symbol;Acc:HGNC:3282] | 3932 | 0.429 | 0.5891 | Yes |
| 42 | ABCE1 | ATP binding cassette subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:69] | 3959 | 0.425 | 0.5961 | Yes |
| 43 | PRPF4 | pre-mRNA processing factor 4 [Source:HGNC Symbol;Acc:HGNC:17349] | 4036 | 0.408 | 0.6014 | Yes |
| 44 | HNRNPK | heterogeneous nuclear ribonucleoprotein K [Source:HGNC Symbol;Acc:HGNC:5044] | 4129 | 0.394 | 0.6061 | Yes |
| 45 | SEM1 | SEM1 26S proteasome complex subunit [Source:HGNC Symbol;Acc:HGNC:10845] | 4355 | 0.352 | 0.6064 | Yes |
| 46 | ILF2 | interleukin enhancer binding factor 2 [Source:HGNC Symbol;Acc:HGNC:6037] | 4434 | 0.339 | 0.6104 | Yes |
| 47 | HNRNPF | heterogeneous nuclear ribonucleoprotein F [Source:HGNC Symbol;Acc:HGNC:5039] | 4955 | 0.250 | 0.6008 | No |
| 48 | DDX39B | DExD-box helicase 39B [Source:HGNC Symbol;Acc:HGNC:13917] | 5025 | 0.239 | 0.6033 | No |
| 49 | SSBP1 | single stranded DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11317] | 5030 | 0.238 | 0.6075 | No |
| 50 | SNRPB2 | small nuclear ribonucleoprotein polypeptide B2 [Source:HGNC Symbol;Acc:HGNC:11155] | 5129 | 0.218 | 0.6088 | No |
| 51 | KPNB1 | karyopherin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:6400] | 5410 | 0.176 | 0.6044 | No |
| 52 | SNRPE | small nuclear ribonucleoprotein polypeptide E [Source:HGNC Symbol;Acc:HGNC:11161] | 5502 | 0.162 | 0.6049 | No |
| 53 | HNRNPC | heterogeneous nuclear ribonucleoprotein C [Source:HGNC Symbol;Acc:HGNC:5035] | 5785 | 0.125 | 0.5995 | No |
| 54 | MCTS1 | MCTS1 re-initiation and release factor [Source:HGNC Symbol;Acc:HGNC:23357] | 5839 | 0.116 | 0.6002 | No |
| 55 | NAE1 | NEDD8 activating enzyme E1 subunit 1 [Source:HGNC Symbol;Acc:HGNC:621] | 5994 | 0.090 | 0.5977 | No |
| 56 | OSR1 | odd-skipped related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:8111] | 19060 | 0.000 | 0.2447 | No |
| 57 | SRSF10 | serine and arginine rich splicing factor 10 [Source:HGNC Symbol;Acc:HGNC:16713] | 27944 | -0.027 | 0.0052 | No |
| 58 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 27997 | -0.031 | 0.0044 | No |
| 59 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 28115 | -0.049 | 0.0021 | No |
| 60 | CAPRIN1 | cell cycle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:6743] | 29336 | -0.221 | -0.0269 | No |
| 61 | CPSF6 | cleavage and polyadenylation specific factor 6 [Source:HGNC Symbol;Acc:HGNC:13871] | 29549 | -0.249 | -0.0281 | No |
| 62 | U2SURP | U2 snRNP associated SURP domain containing [Source:HGNC Symbol;Acc:HGNC:30855] | 29578 | -0.253 | -0.0243 | No |
| 63 | HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13729] | 30190 | -0.339 | -0.0346 | No |
| 64 | BUB3 | BUB3 mitotic checkpoint protein [Source:HGNC Symbol;Acc:HGNC:1151] | 30192 | -0.340 | -0.0285 | No |
| 65 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 30899 | -0.449 | -0.0395 | No |
| 66 | ATP5PB | ATP synthase peripheral stalk-membrane subunit b [Source:HGNC Symbol;Acc:HGNC:840] | 30917 | -0.452 | -0.0318 | No |
| 67 | UQCRC2 | ubiquinol-cytochrome c reductase core protein 2 [Source:HGNC Symbol;Acc:HGNC:12586] | 30949 | -0.455 | -0.0244 | No |
| 68 | SF3B2 | splicing factor 3b subunit 2 [Source:HGNC Symbol;Acc:HGNC:10769] | 31694 | -0.577 | -0.0340 | No |
| 69 | COPS2 | COP9 signalosome subunit 2 [Source:HGNC Symbol;Acc:HGNC:30747] | 32593 | -0.773 | -0.0443 | No |
| 70 | RTCA | RNA 3'-terminal phosphate cyclase [Source:HGNC Symbol;Acc:HGNC:17981] | 33527 | -1.027 | -0.0509 | No |
| 71 | NONO | non-POU domain containing octamer binding [Source:HGNC Symbol;Acc:HGNC:7871] | 33646 | -1.061 | -0.0349 | No |
| 72 | RTRAF | RNA transcription, translation and transport factor [Source:HGNC Symbol;Acc:HGNC:23169] | 33850 | -1.130 | -0.0200 | No |
| 73 | HSPB11 | heat shock protein family B (small) member 11 [Source:HGNC Symbol;Acc:HGNC:25019] | 35299 | -1.729 | -0.0278 | No |
| 74 | GRSF1 | G-rich RNA sequence binding factor 1 [Source:HGNC Symbol;Acc:HGNC:4610] | 35368 | -1.762 | 0.0022 | No |
| 75 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36284 | -2.451 | 0.0218 | No |
