Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | MODULE_76 |
| Enrichment Score (ES) | 0.74314 |
| Normalized Enrichment Score (NES) | 1.847243 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.010955982 |
| FWER p-Value | 0.014 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 0 | 4.989 | 0.0658 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 1 | 4.939 | 0.1309 | Yes |
| 3 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 8 | 4.850 | 0.1947 | Yes |
| 4 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 9 | 4.813 | 0.2581 | Yes |
| 5 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 11 | 4.782 | 0.3211 | Yes |
| 6 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 74 | 3.755 | 0.3690 | Yes |
| 7 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 89 | 3.588 | 0.4159 | Yes |
| 8 | CXCL14 | C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640] | 163 | 3.113 | 0.4550 | Yes |
| 9 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 263 | 2.685 | 0.4877 | Yes |
| 10 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 308 | 2.510 | 0.5196 | Yes |
| 11 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 398 | 2.258 | 0.5470 | Yes |
| 12 | TLR1 | toll like receptor 1 [Source:HGNC Symbol;Acc:HGNC:11847] | 433 | 2.194 | 0.5750 | Yes |
| 13 | TIRAP | TIR domain containing adaptor protein [Source:HGNC Symbol;Acc:HGNC:17192] | 553 | 1.986 | 0.5979 | Yes |
| 14 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 625 | 1.882 | 0.6208 | Yes |
| 15 | ANXA1 | annexin A1 [Source:HGNC Symbol;Acc:HGNC:533] | 871 | 1.587 | 0.6351 | Yes |
| 16 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1097 | 1.398 | 0.6475 | Yes |
| 17 | BCL6 | BCL6 transcription repressor [Source:HGNC Symbol;Acc:HGNC:1001] | 1129 | 1.375 | 0.6648 | Yes |
| 18 | FPR2 | formyl peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:3827] | 1432 | 1.188 | 0.6723 | Yes |
| 19 | TLR3 | toll like receptor 3 [Source:HGNC Symbol;Acc:HGNC:11849] | 1536 | 1.141 | 0.6845 | Yes |
| 20 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 1575 | 1.130 | 0.6984 | Yes |
| 21 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 1728 | 1.050 | 0.7081 | Yes |
| 22 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 2033 | 0.923 | 0.7121 | Yes |
| 23 | AOC3 | amine oxidase copper containing 3 [Source:HGNC Symbol;Acc:HGNC:550] | 2126 | 0.887 | 0.7213 | Yes |
| 24 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 2132 | 0.886 | 0.7329 | Yes |
| 25 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 2177 | 0.871 | 0.7431 | Yes |
| 26 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 3416 | 0.533 | 0.7167 | No |
| 27 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 3429 | 0.530 | 0.7234 | No |
| 28 | ADORA2A | adenosine A2a receptor [Source:HGNC Symbol;Acc:HGNC:263] | 3440 | 0.526 | 0.7301 | No |
| 29 | ABCF1 | ATP binding cassette subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:70] | 3849 | 0.445 | 0.7249 | No |
| 30 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 4000 | 0.415 | 0.7263 | No |
| 31 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 4122 | 0.395 | 0.7283 | No |
| 32 | AOAH | acyloxyacyl hydrolase [Source:HGNC Symbol;Acc:HGNC:548] | 4133 | 0.393 | 0.7332 | No |
| 33 | IL1RAP | interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995] | 4586 | 0.313 | 0.7251 | No |
| 34 | AGER | advanced glycosylation end-product specific receptor [Source:HGNC Symbol;Acc:HGNC:320] | 5641 | 0.140 | 0.6984 | No |
| 35 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 5814 | 0.121 | 0.6954 | No |
| 36 | LY75 | lymphocyte antigen 75 [Source:HGNC Symbol;Acc:HGNC:6729] | 5870 | 0.111 | 0.6954 | No |
| 37 | AOX1 | aldehyde oxidase 1 [Source:HGNC Symbol;Acc:HGNC:553] | 5936 | 0.100 | 0.6949 | No |
| 38 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796] | 6078 | 0.083 | 0.6922 | No |
| 39 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 6488 | 0.014 | 0.6814 | No |
| 40 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6596 | 0.000 | 0.6785 | No |
| 41 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6597 | 0.000 | 0.6785 | No |
| 42 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6616 | 0.000 | 0.6780 | No |
| 43 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6617 | 0.000 | 0.6780 | No |
| 44 | CCL17 | C-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:10615] | 6619 | 0.000 | 0.6779 | No |
| 45 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6626 | 0.000 | 0.6778 | No |
| 46 | CCL21 | C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620] | 6628 | 0.000 | 0.6778 | No |
| 47 | S100A9 | S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499] | 8749 | 0.000 | 0.6205 | No |
| 48 | LY86 | lymphocyte antigen 86 [Source:HGNC Symbol;Acc:HGNC:16837] | 9427 | 0.000 | 0.6022 | No |
| 49 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10904 | 0.000 | 0.5623 | No |
| 50 | S100A12 | S100 calcium binding protein A12 [Source:HGNC Symbol;Acc:HGNC:10489] | 11852 | 0.000 | 0.5367 | No |
| 51 | PTX3 | pentraxin 3 [Source:HGNC Symbol;Acc:HGNC:9692] | 12493 | 0.000 | 0.5194 | No |
| 52 | C4B | complement C4B (Chido blood group) [Source:HGNC Symbol;Acc:HGNC:1324] | 15710 | 0.000 | 0.4325 | No |
| 53 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15970 | 0.000 | 0.4255 | No |
| 54 | C5 | complement C5 [Source:HGNC Symbol;Acc:HGNC:1331] | 16171 | 0.000 | 0.4201 | No |
| 55 | FN1 | fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778] | 16781 | 0.000 | 0.4037 | No |
| 56 | ADORA1 | adenosine A1 receptor [Source:HGNC Symbol;Acc:HGNC:262] | 16821 | 0.000 | 0.4026 | No |
| 57 | MGLL | monoglyceride lipase [Source:HGNC Symbol;Acc:HGNC:17038] | 17208 | 0.000 | 0.3922 | No |
| 58 | IL9 | interleukin 9 [Source:HGNC Symbol;Acc:HGNC:6029] | 17773 | 0.000 | 0.3769 | No |
| 59 | BDKRB2 | bradykinin receptor B2 [Source:HGNC Symbol;Acc:HGNC:1030] | 18005 | 0.000 | 0.3707 | No |
| 60 | ORM1 | orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498] | 18669 | 0.000 | 0.3528 | No |
| 61 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18908 | 0.000 | 0.3464 | No |
| 62 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18946 | 0.000 | 0.3454 | No |
| 63 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 18947 | 0.000 | 0.3454 | No |
| 64 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 19349 | 0.000 | 0.3345 | No |
| 65 | CXCR2 | C-X-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:6027] | 19389 | 0.000 | 0.3335 | No |
| 66 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19466 | 0.000 | 0.3314 | No |
| 67 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19468 | 0.000 | 0.3314 | No |
| 68 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19471 | 0.000 | 0.3313 | No |
| 69 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19480 | 0.000 | 0.3311 | No |
| 70 | PLA2G7 | phospholipase A2 group VII [Source:HGNC Symbol;Acc:HGNC:9040] | 22239 | 0.000 | 0.2566 | No |
| 71 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 23062 | 0.000 | 0.2344 | No |
| 72 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 23064 | 0.000 | 0.2344 | No |
| 73 | AIF1 | allograft inflammatory factor 1 [Source:HGNC Symbol;Acc:HGNC:352] | 27842 | -0.008 | 0.1054 | No |
| 74 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27977 | -0.029 | 0.1022 | No |
| 75 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 28607 | -0.119 | 0.0867 | No |
| 76 | CYBB | cytochrome b-245 beta chain [Source:HGNC Symbol;Acc:HGNC:2578] | 30375 | -0.365 | 0.0438 | No |
| 77 | NFATC4 | nuclear factor of activated T cells 4 [Source:HGNC Symbol;Acc:HGNC:7778] | 30955 | -0.456 | 0.0342 | No |
| 78 | CXCR4 | C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561] | 33862 | -1.133 | -0.0294 | No |
| 79 | LYZ | lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] | 34142 | -1.223 | -0.0208 | No |
| 80 | ALOX5AP | arachidonate 5-lipoxygenase activating protein [Source:HGNC Symbol;Acc:HGNC:436] | 36800 | -3.279 | -0.0494 | No |
| 81 | ALOX5 | arachidonate 5-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:435] | 37058 | -4.337 | 0.0009 | No |
