Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOBP_FATTY_ACID_CATABOLIC_PROCESS |
| Enrichment Score (ES) | -0.76299316 |
| Normalized Enrichment Score (NES) | -1.6283514 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03578325 |
| FWER p-Value | 0.393 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ACOX1 | acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119] | 1199 | 1.330 | -0.0204 | No |
| 2 | MECR | mitochondrial trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:19691] | 1205 | 1.326 | -0.0085 | No |
| 3 | SESN2 | sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746] | 1550 | 1.135 | -0.0076 | No |
| 4 | HAO1 | hydroxyacid oxidase 1 [Source:HGNC Symbol;Acc:HGNC:4809] | 2051 | 0.918 | -0.0128 | No |
| 5 | AIG1 | androgen induced 1 [Source:HGNC Symbol;Acc:HGNC:21607] | 3081 | 0.613 | -0.0351 | No |
| 6 | CPT1B | carnitine palmitoyltransferase 1B [Source:HGNC Symbol;Acc:HGNC:2329] | 3578 | 0.496 | -0.0440 | No |
| 7 | MFSD2A | major facilitator superfamily domain containing 2A [Source:HGNC Symbol;Acc:HGNC:25897] | 4274 | 0.367 | -0.0594 | No |
| 8 | ABHD2 | abhydrolase domain containing 2, acylglycerol lipase [Source:HGNC Symbol;Acc:HGNC:18717] | 5075 | 0.229 | -0.0790 | No |
| 9 | ABHD1 | abhydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17553] | 5112 | 0.221 | -0.0780 | No |
| 10 | ACOXL | acyl-CoA oxidase like [Source:HGNC Symbol;Acc:HGNC:25621] | 5192 | 0.210 | -0.0782 | No |
| 11 | AKT1 | AKT serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:391] | 5379 | 0.179 | -0.0816 | No |
| 12 | PPARD | peroxisome proliferator activated receptor delta [Source:HGNC Symbol;Acc:HGNC:9235] | 5580 | 0.149 | -0.0857 | No |
| 13 | PEX13 | peroxisomal biogenesis factor 13 [Source:HGNC Symbol;Acc:HGNC:8855] | 6293 | 0.043 | -0.1046 | No |
| 14 | EHHADH | enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247] | 8168 | 0.000 | -0.1552 | No |
| 15 | ADIPOQ | adiponectin, C1Q and collagen domain containing [Source:HGNC Symbol;Acc:HGNC:13633] | 8277 | 0.000 | -0.1582 | No |
| 16 | NUDT7 | nudix hydrolase 7 [Source:HGNC Symbol;Acc:HGNC:8054] | 8392 | 0.000 | -0.1612 | No |
| 17 | GLYATL2 | glycine-N-acyltransferase like 2 [Source:HGNC Symbol;Acc:HGNC:24178] | 10508 | 0.000 | -0.2184 | No |
| 18 | SLC27A2 | solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996] | 11078 | 0.000 | -0.2338 | No |
| 19 | DECR1 | 2,4-dienoyl-CoA reductase 1 [Source:HGNC Symbol;Acc:HGNC:2753] | 12350 | 0.000 | -0.2682 | No |
| 20 | ACOX2 | acyl-CoA oxidase 2 [Source:HGNC Symbol;Acc:HGNC:120] | 12462 | 0.000 | -0.2712 | No |
| 21 | CNR1 | cannabinoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:2159] | 12471 | 0.000 | -0.2714 | No |
| 22 | PCK1 | phosphoenolpyruvate carboxykinase 1 [Source:HGNC Symbol;Acc:HGNC:8724] | 15497 | 0.000 | -0.3532 | No |
| 23 | CEL | carboxyl ester lipase [Source:HGNC Symbol;Acc:HGNC:1848] | 15845 | 0.000 | -0.3626 | No |
| 24 | PLIN5 | perilipin 5 [Source:HGNC Symbol;Acc:HGNC:33196] | 15880 | 0.000 | -0.3635 | No |
| 25 | BDH2 | 3-hydroxybutyrate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:32389] | 16221 | 0.000 | -0.3727 | No |
| 26 | TWIST1 | twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428] | 17292 | 0.000 | -0.4016 | No |
| 27 | ADTRP | androgen dependent TFPI regulating protein [Source:HGNC Symbol;Acc:HGNC:21214] | 18502 | 0.000 | -0.4343 | No |
| 28 | LEP | leptin [Source:HGNC Symbol;Acc:HGNC:6553] | 18556 | 0.000 | -0.4357 | No |
| 29 | IRS1 | insulin receptor substrate 1 [Source:HGNC Symbol;Acc:HGNC:6125] | 21920 | 0.000 | -0.5267 | No |
| 30 | IRS2 | insulin receptor substrate 2 [Source:HGNC Symbol;Acc:HGNC:6126] | 21923 | 0.000 | -0.5267 | No |
| 31 | PPARA | peroxisome proliferator activated receptor alpha [Source:HGNC Symbol;Acc:HGNC:9232] | 24292 | 0.000 | -0.5907 | No |
| 32 | HAO2 | hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810] | 25097 | 0.000 | -0.6125 | No |
| 33 | FABP1 | fatty acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3555] | 27132 | 0.000 | -0.6675 | No |
| 34 | PECR | peroxisomal trans-2-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:18281] | 27824 | -0.005 | -0.6861 | No |
| 35 | ACADVL | acyl-CoA dehydrogenase very long chain [Source:HGNC Symbol;Acc:HGNC:92] | 28040 | -0.037 | -0.6916 | No |
| 36 | ILVBL | ilvB acetolactate synthase like [Source:HGNC Symbol;Acc:HGNC:6041] | 28062 | -0.041 | -0.6918 | No |
| 37 | MCAT | malonyl-CoA-acyl carrier protein transacylase [Source:HGNC Symbol;Acc:HGNC:29622] | 28144 | -0.055 | -0.6935 | No |
| 38 | MTOR | mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942] | 28724 | -0.135 | -0.7079 | No |
| 39 | ETFA | electron transfer flavoprotein subunit alpha [Source:HGNC Symbol;Acc:HGNC:3481] | 29315 | -0.217 | -0.7219 | No |
| 40 | AKT2 | AKT serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:392] | 29601 | -0.258 | -0.7273 | No |
| 41 | PEX2 | peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717] | 29683 | -0.269 | -0.7270 | No |
| 42 | DECR2 | 2,4-dienoyl-CoA reductase 2 [Source:HGNC Symbol;Acc:HGNC:2754] | 30473 | -0.379 | -0.7449 | No |
| 43 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 31142 | -0.483 | -0.7586 | Yes |
| 44 | NUDT19 | nudix hydrolase 19 [Source:HGNC Symbol;Acc:HGNC:32036] | 31166 | -0.488 | -0.7548 | Yes |
| 45 | HADHA | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:4801] | 31192 | -0.493 | -0.7510 | Yes |
| 46 | PHYH | phytanoyl-CoA 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:8940] | 31334 | -0.516 | -0.7502 | Yes |
| 47 | ECHDC2 | enoyl-CoA hydratase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23408] | 31354 | -0.519 | -0.7460 | Yes |
| 48 | ABHD3 | abhydrolase domain containing 3, phospholipase [Source:HGNC Symbol;Acc:HGNC:18718] | 31479 | -0.541 | -0.7445 | Yes |
| 49 | ALDH3A2 | aldehyde dehydrogenase 3 family member A2 [Source:HGNC Symbol;Acc:HGNC:403] | 31882 | -0.613 | -0.7498 | Yes |
| 50 | PEX7 | peroxisomal biogenesis factor 7 [Source:HGNC Symbol;Acc:HGNC:8860] | 31888 | -0.614 | -0.7444 | Yes |
| 51 | ECI1 | enoyl-CoA delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:2703] | 32219 | -0.687 | -0.7471 | Yes |
| 52 | ACOT8 | acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919] | 32328 | -0.708 | -0.7436 | Yes |
| 53 | MMAA | metabolism of cobalamin associated A [Source:HGNC Symbol;Acc:HGNC:18871] | 32350 | -0.710 | -0.7377 | Yes |
| 54 | SLC27A4 | solute carrier family 27 member 4 [Source:HGNC Symbol;Acc:HGNC:10998] | 32412 | -0.724 | -0.7328 | Yes |
| 55 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 32450 | -0.733 | -0.7272 | Yes |
| 56 | ETFB | electron transfer flavoprotein subunit beta [Source:HGNC Symbol;Acc:HGNC:3482] | 32494 | -0.744 | -0.7216 | Yes |
| 57 | IVD | isovaleryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:6186] | 32537 | -0.753 | -0.7160 | Yes |
| 58 | LPIN2 | lipin 2 [Source:HGNC Symbol;Acc:HGNC:14450] | 32812 | -0.825 | -0.7159 | Yes |
| 59 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 32931 | -0.855 | -0.7114 | Yes |
| 60 | SLC25A17 | solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987] | 33398 | -0.986 | -0.7150 | Yes |
| 61 | HADHB | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta [Source:HGNC Symbol;Acc:HGNC:4803] | 33740 | -1.089 | -0.7144 | Yes |
| 62 | ETFDH | electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483] | 33959 | -1.171 | -0.7097 | Yes |
| 63 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 33972 | -1.176 | -0.6994 | Yes |
| 64 | ACACB | acetyl-CoA carboxylase beta [Source:HGNC Symbol;Acc:HGNC:85] | 34021 | -1.191 | -0.6899 | Yes |
| 65 | ECHDC1 | ethylmalonyl-CoA decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:21489] | 34030 | -1.194 | -0.6793 | Yes |
| 66 | AMACR | alpha-methylacyl-CoA racemase [Source:HGNC Symbol;Acc:HGNC:451] | 34357 | -1.301 | -0.6764 | Yes |
| 67 | LPIN1 | lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345] | 34455 | -1.336 | -0.6669 | Yes |
| 68 | ACAT1 | acetyl-CoA acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:93] | 34491 | -1.349 | -0.6557 | Yes |
| 69 | CPT1C | carnitine palmitoyltransferase 1C [Source:HGNC Symbol;Acc:HGNC:18540] | 34538 | -1.365 | -0.6446 | Yes |
| 70 | LONP2 | lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598] | 34590 | -1.388 | -0.6334 | Yes |
| 71 | ACADL | acyl-CoA dehydrogenase long chain [Source:HGNC Symbol;Acc:HGNC:88] | 34617 | -1.399 | -0.6214 | Yes |
| 72 | ACBD5 | acyl-CoA binding domain containing 5 [Source:HGNC Symbol;Acc:HGNC:23338] | 34640 | -1.407 | -0.6093 | Yes |
| 73 | PCCA | propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653] | 34748 | -1.443 | -0.5991 | Yes |
| 74 | ACAT2 | acetyl-CoA acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:94] | 34759 | -1.446 | -0.5863 | Yes |
| 75 | ACAD10 | acyl-CoA dehydrogenase family member 10 [Source:HGNC Symbol;Acc:HGNC:21597] | 34765 | -1.449 | -0.5733 | Yes |
| 76 | ACAD11 | acyl-CoA dehydrogenase family member 11 [Source:HGNC Symbol;Acc:HGNC:30211] | 34768 | -1.450 | -0.5603 | Yes |
| 77 | ECHS1 | enoyl-CoA hydratase, short chain 1 [Source:HGNC Symbol;Acc:HGNC:3151] | 34933 | -1.531 | -0.5509 | Yes |
| 78 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 34936 | -1.532 | -0.5371 | Yes |
| 79 | TYSND1 | trypsin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28531] | 34974 | -1.554 | -0.5240 | Yes |
| 80 | ABCD4 | ATP binding cassette subfamily D member 4 [Source:HGNC Symbol;Acc:HGNC:68] | 35087 | -1.619 | -0.5124 | Yes |
| 81 | ACADM | acyl-CoA dehydrogenase medium chain [Source:HGNC Symbol;Acc:HGNC:89] | 35197 | -1.671 | -0.5002 | Yes |
| 82 | SCP2 | sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606] | 35297 | -1.729 | -0.4873 | Yes |
| 83 | ABCD3 | ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67] | 35419 | -1.787 | -0.4744 | Yes |
| 84 | MMUT | methylmalonyl-CoA mutase [Source:HGNC Symbol;Acc:HGNC:7526] | 35421 | -1.788 | -0.4582 | Yes |
| 85 | CPT2 | carnitine palmitoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:2330] | 35443 | -1.805 | -0.4425 | Yes |
| 86 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213] | 35498 | -1.835 | -0.4273 | Yes |
| 87 | MCEE | methylmalonyl-CoA epimerase [Source:HGNC Symbol;Acc:HGNC:16732] | 35693 | -1.967 | -0.4148 | Yes |
| 88 | ACADS | acyl-CoA dehydrogenase short chain [Source:HGNC Symbol;Acc:HGNC:90] | 35888 | -2.122 | -0.4008 | Yes |
| 89 | ECI2 | enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601] | 35952 | -2.174 | -0.3829 | Yes |
| 90 | AUH | AU RNA binding methylglutaconyl-CoA hydratase [Source:HGNC Symbol;Acc:HGNC:890] | 35958 | -2.180 | -0.3633 | Yes |
| 91 | LPIN3 | lipin 3 [Source:HGNC Symbol;Acc:HGNC:14451] | 36050 | -2.243 | -0.3454 | Yes |
| 92 | PLA2G15 | phospholipase A2 group XV [Source:HGNC Symbol;Acc:HGNC:17163] | 36053 | -2.244 | -0.3252 | Yes |
| 93 | HSD17B10 | hydroxysteroid 17-beta dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:4800] | 36094 | -2.272 | -0.3057 | Yes |
| 94 | GCDH | glutaryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4189] | 36111 | -2.286 | -0.2855 | Yes |
| 95 | ETFBKMT | electron transfer flavoprotein subunit beta lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:28739] | 36190 | -2.356 | -0.2663 | Yes |
| 96 | ACAA1 | acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82] | 36210 | -2.370 | -0.2453 | Yes |
| 97 | CRAT | carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342] | 36234 | -2.397 | -0.2243 | Yes |
| 98 | FAAH | fatty acid amide hydrolase [Source:HGNC Symbol;Acc:HGNC:3553] | 36246 | -2.406 | -0.2028 | Yes |
| 99 | CROT | carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:HGNC:2366] | 36258 | -2.425 | -0.1812 | Yes |
| 100 | ACAA2 | acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83] | 36347 | -2.523 | -0.1607 | Yes |
| 101 | ABCD1 | ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61] | 36461 | -2.663 | -0.1397 | Yes |
| 102 | HACL1 | 2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856] | 36603 | -2.883 | -0.1174 | Yes |
| 103 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 36642 | -2.940 | -0.0919 | Yes |
| 104 | HADH | hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799] | 36664 | -2.967 | -0.0656 | Yes |
| 105 | CPT1A | carnitine palmitoyltransferase 1A [Source:HGNC Symbol;Acc:HGNC:2328] | 36933 | -3.693 | -0.0394 | Yes |
| 106 | ABCD2 | ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66] | 37084 | -4.825 | 0.0002 | Yes |
