Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | GOBP_NEGATIVE_REGULATION_OF_AMINE_TRANSPORT |
| Enrichment Score (ES) | -0.9238333 |
| Normalized Enrichment Score (NES) | -1.639532 |
| Nominal p-value | 0.0027510317 |
| FDR q-value | 0.033925984 |
| FWER p-Value | 0.268 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | NPY5R | neuropeptide Y receptor Y5 [Source:HGNC Symbol;Acc:HGNC:7958] | 9317 | 0.000 | -0.2514 | No |
| 2 | AGTR2 | angiotensin II receptor type 2 [Source:HGNC Symbol;Acc:HGNC:338] | 9836 | 0.000 | -0.2653 | No |
| 3 | GRM7 | glutamate metabotropic receptor 7 [Source:HGNC Symbol;Acc:HGNC:4599] | 10140 | 0.000 | -0.2735 | No |
| 4 | CHGA | chromogranin A [Source:HGNC Symbol;Acc:HGNC:1929] | 10712 | 0.000 | -0.2889 | No |
| 5 | CNR1 | cannabinoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:2159] | 12471 | 0.000 | -0.3364 | No |
| 6 | TRH | thyrotropin releasing hormone [Source:HGNC Symbol;Acc:HGNC:12298] | 12823 | 0.000 | -0.3458 | No |
| 7 | P2RY1 | purinergic receptor P2Y1 [Source:HGNC Symbol;Acc:HGNC:8539] | 14260 | 0.000 | -0.3846 | No |
| 8 | RGS4 | regulator of G protein signaling 4 [Source:HGNC Symbol;Acc:HGNC:10000] | 14878 | 0.000 | -0.4012 | No |
| 9 | GHSR | growth hormone secretagogue receptor [Source:HGNC Symbol;Acc:HGNC:4267] | 15277 | 0.000 | -0.4120 | No |
| 10 | CRH | corticotropin releasing hormone [Source:HGNC Symbol;Acc:HGNC:2355] | 15940 | 0.000 | -0.4298 | No |
| 11 | ADRA2C | adrenoceptor alpha 2C [Source:HGNC Symbol;Acc:HGNC:283] | 16579 | 0.000 | -0.4470 | No |
| 12 | ADRA2B | adrenoceptor alpha 2B [Source:HGNC Symbol;Acc:HGNC:282] | 16580 | 0.000 | -0.4470 | No |
| 13 | ADORA1 | adenosine A1 receptor [Source:HGNC Symbol;Acc:HGNC:262] | 16821 | 0.000 | -0.4535 | No |
| 14 | SYT4 | synaptotagmin 4 [Source:HGNC Symbol;Acc:HGNC:11512] | 17059 | 0.000 | -0.4599 | No |
| 15 | DRD2 | dopamine receptor D2 [Source:HGNC Symbol;Acc:HGNC:3023] | 18514 | 0.000 | -0.4991 | No |
| 16 | LEP | leptin [Source:HGNC Symbol;Acc:HGNC:6553] | 18556 | 0.000 | -0.5002 | No |
| 17 | SLC43A1 | solute carrier family 43 member 1 [Source:HGNC Symbol;Acc:HGNC:9225] | 25297 | 0.000 | -0.6821 | No |
| 18 | SNCA | synuclein alpha [Source:HGNC Symbol;Acc:HGNC:11138] | 25961 | 0.000 | -0.7000 | No |
| 19 | HRH3 | histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184] | 27051 | 0.000 | -0.7293 | No |
| 20 | ARL6IP5 | ADP ribosylation factor like GTPase 6 interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:16937] | 27813 | -0.004 | -0.7495 | No |
| 21 | ADRA2A | adrenoceptor alpha 2A [Source:HGNC Symbol;Acc:HGNC:281] | 27953 | -0.029 | -0.7509 | No |
| 22 | P2RY12 | purinergic receptor P2Y12 [Source:HGNC Symbol;Acc:HGNC:18124] | 28919 | -0.158 | -0.7642 | No |
| 23 | SYT11 | synaptotagmin 11 [Source:HGNC Symbol;Acc:HGNC:19239] | 34838 | -1.479 | -0.8040 | Yes |
| 24 | RGS2 | regulator of G protein signaling 2 [Source:HGNC Symbol;Acc:HGNC:9998] | 35904 | -2.135 | -0.6598 | Yes |
| 25 | HTR1B | 5-hydroxytryptamine receptor 1B [Source:HGNC Symbol;Acc:HGNC:5287] | 36953 | -3.790 | -0.3811 | Yes |
| 26 | SLC43A2 | solute carrier family 43 member 2 [Source:HGNC Symbol;Acc:HGNC:23087] | 37082 | -4.749 | 0.0002 | Yes |
