Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | HP_ABNORMALITY_OF_THE_5TH_TOE |
| Enrichment Score (ES) | -0.7719468 |
| Normalized Enrichment Score (NES) | -1.5903361 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.08770902 |
| FWER p-Value | 0.82 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PPP1R15B | protein phosphatase 1 regulatory subunit 15B [Source:HGNC Symbol;Acc:HGNC:14951] | 1115 | 1.385 | -0.0121 | No |
| 2 | DPF2 | double PHD fingers 2 [Source:HGNC Symbol;Acc:HGNC:9964] | 2099 | 0.895 | -0.0270 | No |
| 3 | TRMT10A | tRNA methyltransferase 10A [Source:HGNC Symbol;Acc:HGNC:28403] | 2611 | 0.730 | -0.0313 | No |
| 4 | EXTL3 | exostosin like glycosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:3518] | 3159 | 0.593 | -0.0384 | No |
| 5 | MKKS | McKusick-Kaufman syndrome [Source:HGNC Symbol;Acc:HGNC:7108] | 3310 | 0.559 | -0.0352 | No |
| 6 | PLAA | phospholipase A2 activating protein [Source:HGNC Symbol;Acc:HGNC:9043] | 4390 | 0.346 | -0.0598 | No |
| 7 | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100] | 5289 | 0.194 | -0.0816 | No |
| 8 | SMOC1 | SPARC related modular calcium binding 1 [Source:HGNC Symbol;Acc:HGNC:20318] | 5585 | 0.147 | -0.0876 | No |
| 9 | SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 [Source:HGNC Symbol;Acc:HGNC:11109] | 5613 | 0.144 | -0.0865 | No |
| 10 | TMEM67 | transmembrane protein 67 [Source:HGNC Symbol;Acc:HGNC:28396] | 5736 | 0.132 | -0.0881 | No |
| 11 | ALG3 | ALG3 alpha-1,3- mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:23056] | 5836 | 0.117 | -0.0892 | No |
| 12 | KIAA0825 | KIAA0825 [Source:HGNC Symbol;Acc:HGNC:28532] | 5940 | 0.099 | -0.0907 | No |
| 13 | CEP290 | centrosomal protein 290 [Source:HGNC Symbol;Acc:HGNC:29021] | 5991 | 0.090 | -0.0909 | No |
| 14 | PRKACB | protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381] | 6107 | 0.078 | -0.0930 | No |
| 15 | FREM1 | FRAS1 related extracellular matrix 1 [Source:HGNC Symbol;Acc:HGNC:23399] | 7161 | 0.000 | -0.1214 | No |
| 16 | SOX11 | SRY-box transcription factor 11 [Source:HGNC Symbol;Acc:HGNC:11191] | 9008 | 0.000 | -0.1713 | No |
| 17 | HOXD13 | homeobox D13 [Source:HGNC Symbol;Acc:HGNC:5136] | 13357 | 0.000 | -0.2888 | No |
| 18 | SALL1 | spalt like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10524] | 14143 | 0.000 | -0.3100 | No |
| 19 | EVC | EvC ciliary complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:3497] | 16581 | 0.000 | -0.3758 | No |
| 20 | BMP4 | bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071] | 19102 | 0.000 | -0.4439 | No |
| 21 | GLI3 | GLI family zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:4319] | 21880 | 0.000 | -0.5189 | No |
| 22 | TCTN2 | tectonic family member 2 [Source:HGNC Symbol;Acc:HGNC:25774] | 22577 | 0.000 | -0.5377 | No |
| 23 | CD96 | CD96 molecule [Source:HGNC Symbol;Acc:HGNC:16892] | 23247 | 0.000 | -0.5558 | No |
| 24 | EVC2 | EvC ciliary complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:19747] | 23643 | 0.000 | -0.5665 | No |
| 25 | SOX4 | SRY-box transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:11200] | 26410 | 0.000 | -0.6412 | No |
| 26 | RNF6 | ring finger protein 6 [Source:HGNC Symbol;Acc:HGNC:10069] | 27802 | -0.003 | -0.6787 | No |
| 27 | ARID2 | AT-rich interaction domain 2 [Source:HGNC Symbol;Acc:HGNC:18037] | 28208 | -0.065 | -0.6888 | No |
| 28 | DLEC1 | DLEC1 cilia and flagella associated protein [Source:HGNC Symbol;Acc:HGNC:2899] | 28372 | -0.086 | -0.6921 | No |
| 29 | DYNC2H1 | dynein cytoplasmic 2 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2962] | 28402 | -0.089 | -0.6917 | No |
| 30 | SETD5 | SET domain containing 5 [Source:HGNC Symbol;Acc:HGNC:25566] | 28695 | -0.131 | -0.6979 | No |
| 31 | TMEM216 | transmembrane protein 216 [Source:HGNC Symbol;Acc:HGNC:25018] | 28797 | -0.143 | -0.6988 | No |
| 32 | KCNN3 | potassium calcium-activated channel subfamily N member 3 [Source:HGNC Symbol;Acc:HGNC:6292] | 28970 | -0.167 | -0.7012 | No |
| 33 | CHSY1 | chondroitin sulfate synthase 1 [Source:HGNC Symbol;Acc:HGNC:17198] | 29841 | -0.295 | -0.7209 | No |
| 34 | B9D2 | B9 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28636] | 30126 | -0.333 | -0.7242 | No |
| 35 | SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 [Source:HGNC Symbol;Acc:HGNC:11106] | 30133 | -0.334 | -0.7201 | No |
| 36 | ARID1A | AT-rich interaction domain 1A [Source:HGNC Symbol;Acc:HGNC:11110] | 30413 | -0.370 | -0.7228 | No |
| 37 | C2CD3 | C2 domain containing 3 centriole elongation regulator [Source:HGNC Symbol;Acc:HGNC:24564] | 30714 | -0.418 | -0.7254 | No |
| 38 | MKS1 | MKS transition zone complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:7121] | 31077 | -0.473 | -0.7291 | No |
| 39 | RPGRIP1L | RPGRIP1 like [Source:HGNC Symbol;Acc:HGNC:29168] | 31326 | -0.515 | -0.7291 | No |
| 40 | SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 [Source:HGNC Symbol;Acc:HGNC:11103] | 31889 | -0.614 | -0.7363 | No |
| 41 | RPGRIP1 | RPGR interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:13436] | 33211 | -0.934 | -0.7598 | Yes |
| 42 | PDE6D | phosphodiesterase 6D [Source:HGNC Symbol;Acc:HGNC:8788] | 33214 | -0.935 | -0.7477 | Yes |
| 43 | INPP5E | inositol polyphosphate-5-phosphatase E [Source:HGNC Symbol;Acc:HGNC:21474] | 33448 | -1.003 | -0.7409 | Yes |
| 44 | DDX59 | DEAD-box helicase 59 [Source:HGNC Symbol;Acc:HGNC:25360] | 33452 | -1.004 | -0.7280 | Yes |
| 45 | PIGH | phosphatidylinositol glycan anchor biosynthesis class H [Source:HGNC Symbol;Acc:HGNC:8964] | 33567 | -1.040 | -0.7175 | Yes |
| 46 | CC2D2A | coiled-coil and C2 domain containing 2A [Source:HGNC Symbol;Acc:HGNC:29253] | 33588 | -1.043 | -0.7045 | Yes |
| 47 | CEP120 | centrosomal protein 120 [Source:HGNC Symbol;Acc:HGNC:26690] | 33739 | -1.089 | -0.6944 | Yes |
| 48 | LMBR1 | limb development membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:13243] | 33836 | -1.126 | -0.6824 | Yes |
| 49 | CSPP1 | centrosome and spindle pole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:26193] | 33879 | -1.139 | -0.6687 | Yes |
| 50 | SC5D | sterol-C5-desaturase [Source:HGNC Symbol;Acc:HGNC:10547] | 34161 | -1.231 | -0.6603 | Yes |
| 51 | TMEM107 | transmembrane protein 107 [Source:HGNC Symbol;Acc:HGNC:28128] | 34460 | -1.339 | -0.6509 | Yes |
| 52 | IFT80 | intraflagellar transport 80 [Source:HGNC Symbol;Acc:HGNC:29262] | 34479 | -1.344 | -0.6339 | Yes |
| 53 | TTC21B | tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660] | 34481 | -1.345 | -0.6164 | Yes |
| 54 | B9D1 | B9 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24123] | 34738 | -1.439 | -0.6047 | Yes |
| 55 | TMEM231 | transmembrane protein 231 [Source:HGNC Symbol;Acc:HGNC:37234] | 34788 | -1.456 | -0.5870 | Yes |
| 56 | CKAP2L | cytoskeleton associated protein 2 like [Source:HGNC Symbol;Acc:HGNC:26877] | 34930 | -1.530 | -0.5710 | Yes |
| 57 | NEK1 | NIMA related kinase 1 [Source:HGNC Symbol;Acc:HGNC:7744] | 35255 | -1.707 | -0.5575 | Yes |
| 58 | BBS2 | Bardet-Biedl syndrome 2 [Source:HGNC Symbol;Acc:HGNC:967] | 35517 | -1.846 | -0.5406 | Yes |
| 59 | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 [Source:HGNC Symbol;Acc:HGNC:11105] | 35550 | -1.867 | -0.5171 | Yes |
| 60 | LBR | lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518] | 35876 | -2.113 | -0.4985 | Yes |
| 61 | TGFBR2 | transforming growth factor beta receptor 2 [Source:HGNC Symbol;Acc:HGNC:11773] | 36059 | -2.246 | -0.4742 | Yes |
| 62 | IFT172 | intraflagellar transport 172 [Source:HGNC Symbol;Acc:HGNC:30391] | 36340 | -2.513 | -0.4491 | Yes |
| 63 | ARID1B | AT-rich interaction domain 1B [Source:HGNC Symbol;Acc:HGNC:18040] | 36368 | -2.550 | -0.4166 | Yes |
| 64 | CEP55 | centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161] | 36433 | -2.620 | -0.3843 | Yes |
| 65 | KCNJ2 | potassium inwardly rectifying channel subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:6263] | 36452 | -2.649 | -0.3503 | Yes |
| 66 | WDR19 | WD repeat domain 19 [Source:HGNC Symbol;Acc:HGNC:18340] | 36459 | -2.656 | -0.3160 | Yes |
| 67 | WWOX | WW domain containing oxidoreductase [Source:HGNC Symbol;Acc:HGNC:12799] | 36487 | -2.702 | -0.2816 | Yes |
| 68 | DHCR7 | 7-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2860] | 36576 | -2.839 | -0.2470 | Yes |
| 69 | CIBAR1 | CBY1 interacting BAR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30452] | 36584 | -2.862 | -0.2100 | Yes |
| 70 | NPHP3 | nephrocystin 3 [Source:HGNC Symbol;Acc:HGNC:7907] | 36606 | -2.886 | -0.1730 | Yes |
| 71 | KIF7 | kinesin family member 7 [Source:HGNC Symbol;Acc:HGNC:30497] | 36692 | -3.041 | -0.1358 | Yes |
| 72 | WDPCP | WD repeat containing planar cell polarity effector [Source:HGNC Symbol;Acc:HGNC:28027] | 36744 | -3.144 | -0.0963 | Yes |
| 73 | IFT140 | intraflagellar transport 140 [Source:HGNC Symbol;Acc:HGNC:29077] | 36977 | -3.857 | -0.0524 | Yes |
| 74 | DYNC2LI1 | dynein cytoplasmic 2 light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:24595] | 37037 | -4.261 | 0.0014 | Yes |
