Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | CSR_EARLY_UP.V1_DN |
| Enrichment Score (ES) | -0.644994 |
| Normalized Enrichment Score (NES) | -1.3961594 |
| Nominal p-value | 0.004530011 |
| FDR q-value | 0.08191111 |
| FWER p-Value | 0.572 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 406 | 2.252 | 0.0113 | No |
| 2 | MINDY1 | MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648] | 849 | 1.610 | 0.0154 | No |
| 3 | ZNF585B | zinc finger protein 585B [Source:HGNC Symbol;Acc:HGNC:30948] | 1011 | 1.465 | 0.0255 | No |
| 4 | IP6K2 | inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313] | 1110 | 1.390 | 0.0367 | No |
| 5 | GRHL1 | grainyhead like transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:17923] | 1365 | 1.230 | 0.0420 | No |
| 6 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 1633 | 1.095 | 0.0456 | No |
| 7 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 1871 | 0.990 | 0.0490 | No |
| 8 | NR1H3 | nuclear receptor subfamily 1 group H member 3 [Source:HGNC Symbol;Acc:HGNC:7966] | 2621 | 0.727 | 0.0360 | No |
| 9 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 2650 | 0.717 | 0.0423 | No |
| 10 | CC2D1A | coiled-coil and C2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:30237] | 2771 | 0.689 | 0.0459 | No |
| 11 | TRIM56 | tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028] | 3096 | 0.609 | 0.0432 | No |
| 12 | LTN1 | listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082] | 3449 | 0.525 | 0.0389 | No |
| 13 | NDNF | neuron derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:26256] | 3742 | 0.463 | 0.0356 | No |
| 14 | RNF20 | ring finger protein 20 [Source:HGNC Symbol;Acc:HGNC:10062] | 3853 | 0.444 | 0.0370 | No |
| 15 | LRIG2 | leucine rich repeats and immunoglobulin like domains 2 [Source:HGNC Symbol;Acc:HGNC:20889] | 3900 | 0.435 | 0.0400 | No |
| 16 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 4626 | 0.308 | 0.0235 | No |
| 17 | FBXO38 | F-box protein 38 [Source:HGNC Symbol;Acc:HGNC:28844] | 5069 | 0.231 | 0.0138 | No |
| 18 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 5312 | 0.190 | 0.0092 | No |
| 19 | TENT5C | terminal nucleotidyltransferase 5C [Source:HGNC Symbol;Acc:HGNC:24712] | 5594 | 0.146 | 0.0030 | No |
| 20 | ZNF33A | zinc finger protein 33A [Source:HGNC Symbol;Acc:HGNC:13096] | 5676 | 0.140 | 0.0022 | No |
| 21 | SAG | S-antigen visual arrestin [Source:HGNC Symbol;Acc:HGNC:10521] | 6360 | 0.029 | -0.0160 | No |
| 22 | DAAM2 | dishevelled associated activator of morphogenesis 2 [Source:HGNC Symbol;Acc:HGNC:18143] | 7158 | 0.000 | -0.0375 | No |
| 23 | ASPA | aspartoacylase [Source:HGNC Symbol;Acc:HGNC:756] | 7999 | 0.000 | -0.0603 | No |
| 24 | PMS2P1 | PMS1 homolog 2, mismatch repair system component pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9123] | 8136 | 0.000 | -0.0639 | No |
| 25 | TDRD6 | tudor domain containing 6 [Source:HGNC Symbol;Acc:HGNC:21339] | 9306 | 0.000 | -0.0956 | No |
| 26 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 10492 | 0.000 | -0.1276 | No |
| 27 | GFRA1 | GDNF family receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4243] | 11384 | 0.000 | -0.1517 | No |
| 28 | ERAP2 | endoplasmic reticulum aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:29499] | 11636 | 0.000 | -0.1585 | No |
| 29 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 13025 | 0.000 | -0.1961 | No |
| 30 | GSDMB | gasdermin B [Source:HGNC Symbol;Acc:HGNC:23690] | 13331 | 0.000 | -0.2043 | No |
| 31 | CDRT4 | CMT1A duplicated region transcript 4 [Source:HGNC Symbol;Acc:HGNC:14383] | 13498 | 0.000 | -0.2088 | No |
| 32 | GDF5 | growth differentiation factor 5 [Source:HGNC Symbol;Acc:HGNC:4220] | 13559 | 0.000 | -0.2104 | No |
| 33 | PDE5A | phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784] | 13648 | 0.000 | -0.2128 | No |
| 34 | NYNRIN | NYN domain and retroviral integrase containing [Source:HGNC Symbol;Acc:HGNC:20165] | 14093 | 0.000 | -0.2248 | No |
| 35 | HOXA10 | homeobox A10 [Source:HGNC Symbol;Acc:HGNC:5100] | 14444 | 0.000 | -0.2343 | No |
| 36 | STOX1 | storkhead box 1 [Source:HGNC Symbol;Acc:HGNC:23508] | 15952 | 0.000 | -0.2751 | No |
| 37 | MAB21L1 | mab-21 like 1 [Source:HGNC Symbol;Acc:HGNC:6757] | 15960 | 0.000 | -0.2752 | No |
| 38 | SLC7A14 | solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326] | 16329 | 0.000 | -0.2852 | No |
| 39 | PAPLN | papilin, proteoglycan like sulfated glycoprotein [Source:HGNC Symbol;Acc:HGNC:19262] | 17948 | 0.000 | -0.3290 | No |
| 40 | C14orf132 | chromosome 14 open reading frame 132 [Source:HGNC Symbol;Acc:HGNC:20346] | 17966 | 0.000 | -0.3294 | No |
| 41 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18477 | 0.000 | -0.3432 | No |
| 42 | SULF1 | sulfatase 1 [Source:HGNC Symbol;Acc:HGNC:20391] | 21910 | 0.000 | -0.4361 | No |
| 43 | ZNF337 | zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809] | 22624 | 0.000 | -0.4554 | No |
| 44 | ZNF302 | zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848] | 22667 | 0.000 | -0.4565 | No |
| 45 | CYP2R1 | cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580] | 22864 | 0.000 | -0.4618 | No |
| 46 | CAVIN2 | caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690] | 23861 | 0.000 | -0.4887 | No |
| 47 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 25945 | 0.000 | -0.5451 | No |
| 48 | SNPH | syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931] | 26104 | 0.000 | -0.5494 | No |
| 49 | NSUN5P2 | NSUN5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16609] | 26297 | 0.000 | -0.5546 | No |
| 50 | PLCD1 | phospholipase C delta 1 [Source:HGNC Symbol;Acc:HGNC:9060] | 26349 | 0.000 | -0.5559 | No |
| 51 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 27539 | 0.000 | -0.5881 | No |
| 52 | SLC9A7 | solute carrier family 9 member A7 [Source:HGNC Symbol;Acc:HGNC:17123] | 28400 | -0.089 | -0.6105 | No |
| 53 | RABGAP1 | RAB GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:17155] | 28454 | -0.098 | -0.6110 | No |
| 54 | ZFP64 | ZFP64 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:15940] | 28480 | -0.102 | -0.6106 | No |
| 55 | TCAIM | T cell activation inhibitor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25241] | 28587 | -0.115 | -0.6123 | No |
| 56 | CROCCP2 | CROCC pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:28170] | 28611 | -0.120 | -0.6118 | No |
| 57 | SLC25A46 | solute carrier family 25 member 46 [Source:HGNC Symbol;Acc:HGNC:25198] | 28650 | -0.124 | -0.6116 | No |
| 58 | MSRB1 | methionine sulfoxide reductase B1 [Source:HGNC Symbol;Acc:HGNC:14133] | 28918 | -0.158 | -0.6172 | No |
| 59 | EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 [Source:HGNC Symbol;Acc:HGNC:3290] | 29614 | -0.260 | -0.6335 | No |
| 60 | PHIP | pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673] | 29658 | -0.264 | -0.6320 | No |
| 61 | STX16 | syntaxin 16 [Source:HGNC Symbol;Acc:HGNC:11431] | 29660 | -0.265 | -0.6294 | No |
| 62 | PRRT2 | proline rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30500] | 29771 | -0.286 | -0.6295 | No |
| 63 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:16629] | 29950 | -0.310 | -0.6313 | No |
| 64 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 30393 | -0.368 | -0.6396 | No |
| 65 | ATF7IP | activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092] | 30594 | -0.400 | -0.6410 | Yes |
| 66 | ZFYVE1 | zinc finger FYVE-type containing 1 [Source:HGNC Symbol;Acc:HGNC:13180] | 30631 | -0.407 | -0.6380 | Yes |
| 67 | GTPBP8 | GTP binding protein 8 (putative) [Source:HGNC Symbol;Acc:HGNC:25007] | 30727 | -0.421 | -0.6364 | Yes |
| 68 | ADAMTSL4 | ADAMTS like 4 [Source:HGNC Symbol;Acc:HGNC:19706] | 30861 | -0.443 | -0.6356 | Yes |
| 69 | USP33 | ubiquitin specific peptidase 33 [Source:HGNC Symbol;Acc:HGNC:20059] | 30902 | -0.449 | -0.6322 | Yes |
| 70 | ELMOD3 | ELMO domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26158] | 30927 | -0.452 | -0.6284 | Yes |
| 71 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 31117 | -0.479 | -0.6287 | Yes |
| 72 | KBTBD6 | kelch repeat and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:25340] | 31228 | -0.500 | -0.6267 | Yes |
| 73 | MOSPD2 | motile sperm domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28381] | 31257 | -0.504 | -0.6225 | Yes |
| 74 | HEBP2 | heme binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15716] | 31296 | -0.509 | -0.6185 | Yes |
| 75 | ZNF226 | zinc finger protein 226 [Source:HGNC Symbol;Acc:HGNC:13019] | 31355 | -0.519 | -0.6149 | Yes |
| 76 | ZNF500 | zinc finger protein 500 [Source:HGNC Symbol;Acc:HGNC:23716] | 31417 | -0.530 | -0.6113 | Yes |
| 77 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 31438 | -0.533 | -0.6066 | Yes |
| 78 | ARL4D | ADP ribosylation factor like GTPase 4D [Source:HGNC Symbol;Acc:HGNC:656] | 31623 | -0.565 | -0.6059 | Yes |
| 79 | DXO | decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992] | 31698 | -0.577 | -0.6022 | Yes |
| 80 | TFAP2A | transcription factor AP-2 alpha [Source:HGNC Symbol;Acc:HGNC:11742] | 31952 | -0.630 | -0.6028 | Yes |
| 81 | NATD1 | N-acetyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30770] | 32193 | -0.681 | -0.6025 | Yes |
| 82 | ABCC10 | ATP binding cassette subfamily C member 10 [Source:HGNC Symbol;Acc:HGNC:52] | 32286 | -0.701 | -0.5981 | Yes |
| 83 | ALDH3B2 | aldehyde dehydrogenase 3 family member B2 [Source:HGNC Symbol;Acc:HGNC:411] | 32549 | -0.757 | -0.5977 | Yes |
| 84 | PAN2 | poly(A) specific ribonuclease subunit PAN2 [Source:HGNC Symbol;Acc:HGNC:20074] | 32622 | -0.776 | -0.5919 | Yes |
| 85 | SIX1 | SIX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10887] | 32727 | -0.805 | -0.5868 | Yes |
| 86 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 32857 | -0.837 | -0.5819 | Yes |
| 87 | LRRK2 | leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618] | 32917 | -0.851 | -0.5751 | Yes |
| 88 | UBN2 | ubinuclein 2 [Source:HGNC Symbol;Acc:HGNC:21931] | 32997 | -0.872 | -0.5686 | Yes |
| 89 | YEATS2 | YEATS domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25489] | 33114 | -0.902 | -0.5628 | Yes |
| 90 | ZNF467 | zinc finger protein 467 [Source:HGNC Symbol;Acc:HGNC:23154] | 33268 | -0.950 | -0.5575 | Yes |
| 91 | AMT | aminomethyltransferase [Source:HGNC Symbol;Acc:HGNC:473] | 33336 | -0.967 | -0.5497 | Yes |
| 92 | AKIP1 | A-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1170] | 33559 | -1.038 | -0.5454 | Yes |
| 93 | LRIG3 | leucine rich repeats and immunoglobulin like domains 3 [Source:HGNC Symbol;Acc:HGNC:30991] | 33655 | -1.065 | -0.5374 | Yes |
| 94 | SLC16A7 | solute carrier family 16 member 7 [Source:HGNC Symbol;Acc:HGNC:10928] | 34000 | -1.185 | -0.5350 | Yes |
| 95 | ACBD4 | acyl-CoA binding domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23337] | 34140 | -1.222 | -0.5266 | Yes |
| 96 | UFSP2 | UFM1 specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:25640] | 34212 | -1.249 | -0.5162 | Yes |
| 97 | CIRBP | cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982] | 34508 | -1.357 | -0.5107 | Yes |
| 98 | BRD8 | bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874] | 34513 | -1.359 | -0.4973 | Yes |
| 99 | DDX17 | DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740] | 34515 | -1.360 | -0.4839 | Yes |
| 100 | LDB1 | LIM domain binding 1 [Source:HGNC Symbol;Acc:HGNC:6532] | 34611 | -1.397 | -0.4726 | Yes |
| 101 | OTUD1 | OTU deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:27346] | 34656 | -1.411 | -0.4598 | Yes |
| 102 | POLL | DNA polymerase lambda [Source:HGNC Symbol;Acc:HGNC:9184] | 34660 | -1.414 | -0.4458 | Yes |
| 103 | FBXO25 | F-box protein 25 [Source:HGNC Symbol;Acc:HGNC:13596] | 34859 | -1.492 | -0.4364 | Yes |
| 104 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 34931 | -1.530 | -0.4232 | Yes |
| 105 | DCP1B | decapping mRNA 1B [Source:HGNC Symbol;Acc:HGNC:24451] | 35007 | -1.568 | -0.4096 | Yes |
| 106 | MRI1 | methylthioribose-1-phosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:28469] | 35053 | -1.599 | -0.3950 | Yes |
| 107 | ARRDC3 | arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263] | 35126 | -1.640 | -0.3807 | Yes |
| 108 | NMT2 | N-myristoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:7858] | 35145 | -1.649 | -0.3648 | Yes |
| 109 | NDUFAF7 | NADH:ubiquinone oxidoreductase complex assembly factor 7 [Source:HGNC Symbol;Acc:HGNC:28816] | 35241 | -1.698 | -0.3505 | Yes |
| 110 | ALDH1L2 | aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777] | 35374 | -1.763 | -0.3366 | Yes |
| 111 | C2CD5 | C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062] | 35458 | -1.813 | -0.3209 | Yes |
| 112 | ING4 | inhibitor of growth family member 4 [Source:HGNC Symbol;Acc:HGNC:19423] | 35648 | -1.936 | -0.3068 | Yes |
| 113 | ACYP1 | acylphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:179] | 35704 | -1.980 | -0.2887 | Yes |
| 114 | SIX5 | SIX homeobox 5 [Source:HGNC Symbol;Acc:HGNC:10891] | 35707 | -1.981 | -0.2691 | Yes |
| 115 | CDKN1B | cyclin dependent kinase inhibitor 1B [Source:HGNC Symbol;Acc:HGNC:1785] | 35764 | -2.028 | -0.2505 | Yes |
| 116 | ANKZF1 | ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:25527] | 35803 | -2.063 | -0.2311 | Yes |
| 117 | MPPE1 | metallophosphoesterase 1 [Source:HGNC Symbol;Acc:HGNC:15988] | 35911 | -2.142 | -0.2127 | Yes |
| 118 | CKB | creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991] | 35929 | -2.153 | -0.1918 | Yes |
| 119 | FZD2 | frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040] | 36171 | -2.345 | -0.1751 | Yes |
| 120 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36328 | -2.503 | -0.1545 | Yes |
| 121 | HBP1 | HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200] | 36337 | -2.510 | -0.1298 | Yes |
| 122 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36455 | -2.653 | -0.1067 | Yes |
| 123 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 36586 | -2.867 | -0.0818 | Yes |
| 124 | NPHP3 | nephrocystin 3 [Source:HGNC Symbol;Acc:HGNC:7907] | 36606 | -2.886 | -0.0537 | Yes |
| 125 | FUT10 | fucosyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19234] | 36807 | -3.288 | -0.0265 | Yes |
| 126 | ACCS | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) [Source:HGNC Symbol;Acc:HGNC:23989] | 36852 | -3.439 | 0.0064 | Yes |
