Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | RB_DN.V1_DN |
| Enrichment Score (ES) | 0.52080697 |
| Normalized Enrichment Score (NES) | 1.3517911 |
| Nominal p-value | 0.008 |
| FDR q-value | 0.078355044 |
| FWER p-Value | 0.299 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 21 | 4.540 | 0.0439 | Yes |
| 2 | CISH | cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] | 25 | 4.461 | 0.0874 | Yes |
| 3 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 35 | 4.335 | 0.1296 | Yes |
| 4 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 47 | 4.131 | 0.1697 | Yes |
| 5 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 68 | 3.816 | 0.2065 | Yes |
| 6 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 192 | 2.933 | 0.2319 | Yes |
| 7 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 253 | 2.723 | 0.2569 | Yes |
| 8 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 443 | 2.174 | 0.2731 | Yes |
| 9 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 551 | 1.990 | 0.2896 | Yes |
| 10 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 632 | 1.868 | 0.3058 | Yes |
| 11 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 681 | 1.820 | 0.3223 | Yes |
| 12 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 825 | 1.630 | 0.3344 | Yes |
| 13 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 840 | 1.619 | 0.3498 | Yes |
| 14 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 905 | 1.549 | 0.3632 | Yes |
| 15 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] | 992 | 1.477 | 0.3754 | Yes |
| 16 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 995 | 1.474 | 0.3897 | Yes |
| 17 | UROS | uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592] | 1244 | 1.303 | 0.3958 | Yes |
| 18 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 1266 | 1.291 | 0.4078 | Yes |
| 19 | ANKFY1 | ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763] | 1524 | 1.145 | 0.4121 | Yes |
| 20 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 1602 | 1.113 | 0.4209 | Yes |
| 21 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 1614 | 1.105 | 0.4314 | Yes |
| 22 | DYNLL1 | dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476] | 1732 | 1.047 | 0.4385 | Yes |
| 23 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 1914 | 0.970 | 0.4431 | Yes |
| 24 | PSMB10 | proteasome 20S subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538] | 1977 | 0.949 | 0.4507 | Yes |
| 25 | MSMO1 | methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] | 2082 | 0.899 | 0.4567 | Yes |
| 26 | PRKAR1A | protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388] | 2092 | 0.897 | 0.4652 | Yes |
| 27 | DDX3Y | DEAD-box helicase 3 Y-linked [Source:HGNC Symbol;Acc:HGNC:2699] | 2162 | 0.875 | 0.4719 | Yes |
| 28 | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769] | 2173 | 0.871 | 0.4802 | Yes |
| 29 | PPP2R1B | protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303] | 2207 | 0.861 | 0.4877 | Yes |
| 30 | BCCIP | BRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNC:978] | 2306 | 0.825 | 0.4931 | Yes |
| 31 | UBA5 | ubiquitin like modifier activating enzyme 5 [Source:HGNC Symbol;Acc:HGNC:23230] | 2355 | 0.808 | 0.4997 | Yes |
| 32 | BASP1 | brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957] | 2374 | 0.800 | 0.5071 | Yes |
| 33 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 2375 | 0.800 | 0.5149 | Yes |
| 34 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 2755 | 0.692 | 0.5114 | Yes |
| 35 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 2991 | 0.632 | 0.5112 | Yes |
| 36 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 3231 | 0.576 | 0.5104 | Yes |
| 37 | SARAF | store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789] | 3336 | 0.553 | 0.5130 | Yes |
| 38 | SH3BP5L | SH3 binding domain protein 5 like [Source:HGNC Symbol;Acc:HGNC:29360] | 3360 | 0.548 | 0.5178 | Yes |
| 39 | EIF4E | eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287] | 3637 | 0.486 | 0.5151 | Yes |
| 40 | TMEM42 | transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444] | 3673 | 0.478 | 0.5188 | Yes |
| 41 | FEZ2 | fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660] | 3765 | 0.459 | 0.5208 | Yes |
| 42 | NKAP | NFKB activating protein [Source:HGNC Symbol;Acc:HGNC:29873] | 4073 | 0.404 | 0.5165 | No |
| 43 | ARL1 | ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692] | 4152 | 0.391 | 0.5182 | No |
| 44 | STARD3NL | STARD3 N-terminal like [Source:HGNC Symbol;Acc:HGNC:19169] | 4444 | 0.336 | 0.5136 | No |
| 45 | LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606] | 4491 | 0.329 | 0.5156 | No |
| 46 | UNC119B | unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488] | 4590 | 0.312 | 0.5160 | No |
| 47 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 4766 | 0.285 | 0.5140 | No |
| 48 | EFL1 | elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789] | 4778 | 0.283 | 0.5165 | No |
| 49 | PDCD6 | programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765] | 4871 | 0.265 | 0.5166 | No |
| 50 | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217] | 4966 | 0.249 | 0.5165 | No |
| 51 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 5213 | 0.206 | 0.5119 | No |
| 52 | TMCC3 | transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199] | 5391 | 0.177 | 0.5088 | No |
| 53 | ANKRD40 | ankyrin repeat domain 40 [Source:HGNC Symbol;Acc:HGNC:28233] | 5688 | 0.139 | 0.5022 | No |
| 54 | P4HA1 | prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546] | 5754 | 0.129 | 0.5017 | No |
| 55 | MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693] | 6313 | 0.039 | 0.4870 | No |
| 56 | SLC7A3 | solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061] | 6397 | 0.026 | 0.4850 | No |
| 57 | DDIT4 | DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944] | 6446 | 0.023 | 0.4839 | No |
| 58 | SMIM3 | small integral membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:30248] | 6732 | 0.000 | 0.4762 | No |
| 59 | CALCB | calcitonin related polypeptide beta [Source:HGNC Symbol;Acc:HGNC:1438] | 8953 | 0.000 | 0.4161 | No |
| 60 | LCE5A | late cornified envelope 5A [Source:HGNC Symbol;Acc:HGNC:16614] | 9566 | 0.000 | 0.3996 | No |
| 61 | RASL11B | RAS like family 11 member B [Source:HGNC Symbol;Acc:HGNC:23804] | 9917 | 0.000 | 0.3901 | No |
| 62 | ADAM12 | ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190] | 10106 | 0.000 | 0.3850 | No |
| 63 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11131 | 0.000 | 0.3573 | No |
| 64 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11249 | 0.000 | 0.3542 | No |
| 65 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 11289 | 0.000 | 0.3531 | No |
| 66 | S100A16 | S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:20441] | 11849 | 0.000 | 0.3380 | No |
| 67 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11924 | 0.000 | 0.3360 | No |
| 68 | AGR3 | anterior gradient 3, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:24167] | 12242 | 0.000 | 0.3274 | No |
| 69 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12608 | 0.000 | 0.3175 | No |
| 70 | MOXD1 | monooxygenase DBH like 1 [Source:HGNC Symbol;Acc:HGNC:21063] | 13148 | 0.000 | 0.3029 | No |
| 71 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13969 | 0.000 | 0.2808 | No |
| 72 | TLL1 | tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843] | 14277 | 0.000 | 0.2725 | No |
| 73 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16423 | 0.000 | 0.2144 | No |
| 74 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17187 | 0.000 | 0.1938 | No |
| 75 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 18025 | 0.000 | 0.1712 | No |
| 76 | BNC1 | basonuclin 1 [Source:HGNC Symbol;Acc:HGNC:1081] | 19293 | 0.000 | 0.1369 | No |
| 77 | GJB2 | gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] | 21036 | 0.000 | 0.0898 | No |
| 78 | F2RL1 | F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538] | 21286 | 0.000 | 0.0830 | No |
| 79 | IRX4 | iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129] | 22003 | 0.000 | 0.0637 | No |
| 80 | CAV1 | caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527] | 22469 | 0.000 | 0.0511 | No |
| 81 | LRRC4 | leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586] | 22917 | 0.000 | 0.0390 | No |
| 82 | LAMC2 | laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493] | 23910 | 0.000 | 0.0122 | No |
| 83 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 23940 | 0.000 | 0.0114 | No |
| 84 | C18orf32 | chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690] | 24721 | 0.000 | -0.0097 | No |
| 85 | CST9 | cystatin 9 [Source:HGNC Symbol;Acc:HGNC:13261] | 24926 | 0.000 | -0.0152 | No |
| 86 | WNT3 | Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782] | 25334 | 0.000 | -0.0263 | No |
| 87 | FHL1 | four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702] | 26093 | 0.000 | -0.0468 | No |
| 88 | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870] | 27269 | 0.000 | -0.0785 | No |
| 89 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 27919 | -0.023 | -0.0959 | No |
| 90 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 27986 | -0.029 | -0.0974 | No |
| 91 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 28084 | -0.044 | -0.0996 | No |
| 92 | GOSR2 | golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431] | 28282 | -0.075 | -0.1042 | No |
| 93 | RPS2 | ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404] | 28526 | -0.106 | -0.1097 | No |
| 94 | DDIT3 | DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726] | 28969 | -0.166 | -0.1200 | No |
| 95 | LMAN1 | lectin, mannose binding 1 [Source:HGNC Symbol;Acc:HGNC:6631] | 29016 | -0.173 | -0.1196 | No |
| 96 | CELSR1 | cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850] | 29111 | -0.186 | -0.1203 | No |
| 97 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 29395 | -0.231 | -0.1257 | No |
| 98 | NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733] | 29527 | -0.245 | -0.1268 | No |
| 99 | SEC23A | Sec23 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10701] | 29885 | -0.302 | -0.1335 | No |
| 100 | H2BC14 | H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750] | 31302 | -0.510 | -0.1669 | No |
| 101 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 31438 | -0.533 | -0.1653 | No |
| 102 | LIFR | LIF receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6597] | 31567 | -0.557 | -0.1633 | No |
| 103 | TMEM50B | transmembrane protein 50B [Source:HGNC Symbol;Acc:HGNC:1280] | 31608 | -0.562 | -0.1589 | No |
| 104 | ANXA11 | annexin A11 [Source:HGNC Symbol;Acc:HGNC:535] | 32308 | -0.704 | -0.1709 | No |
| 105 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 32613 | -0.775 | -0.1716 | No |
| 106 | CTNNAL1 | catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] | 32702 | -0.796 | -0.1662 | No |
| 107 | CREB3L2 | cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720] | 33134 | -0.908 | -0.1689 | No |
| 108 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 33177 | -0.920 | -0.1611 | No |
| 109 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 33600 | -1.049 | -0.1622 | No |
| 110 | CYTH1 | cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501] | 33717 | -1.082 | -0.1548 | No |
| 111 | DNAJC4 | DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271] | 33929 | -1.160 | -0.1491 | No |
| 112 | CDC42SE2 | CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547] | 34019 | -1.190 | -0.1399 | No |
| 113 | TRAPPC12 | trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284] | 34092 | -1.207 | -0.1300 | No |
| 114 | MYORG | myogenesis regulating glycosidase (putative) [Source:HGNC Symbol;Acc:HGNC:19918] | 34592 | -1.388 | -0.1299 | No |
| 115 | PLXNA2 | plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100] | 35001 | -1.564 | -0.1257 | No |
| 116 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 35081 | -1.617 | -0.1120 | No |
| 117 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 35138 | -1.646 | -0.0974 | No |
| 118 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 35382 | -1.767 | -0.0867 | No |
| 119 | H2BC4 | H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757] | 35683 | -1.962 | -0.0756 | No |
| 120 | FAM102A | family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419] | 36107 | -2.286 | -0.0647 | No |
| 121 | NDRG1 | N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679] | 36464 | -2.668 | -0.0482 | No |
| 122 | COL18A1 | collagen type XVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2195] | 36596 | -2.878 | -0.0236 | No |
| 123 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36945 | -3.773 | 0.0039 | No |
