Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_DN.V1_UP |
| Enrichment Score (ES) | -0.6568143 |
| Normalized Enrichment Score (NES) | -1.40919 |
| Nominal p-value | 0.0034207525 |
| FDR q-value | 0.07160504 |
| FWER p-Value | 0.482 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 18 | 4.578 | 0.0317 | No |
| 2 | ID1 | inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360] | 27 | 4.439 | 0.0627 | No |
| 3 | PLA2G6 | phospholipase A2 group VI [Source:HGNC Symbol;Acc:HGNC:9039] | 383 | 2.296 | 0.0692 | No |
| 4 | BTG2 | BTG anti-proliferation factor 2 [Source:HGNC Symbol;Acc:HGNC:1131] | 477 | 2.119 | 0.0816 | No |
| 5 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 677 | 1.824 | 0.0890 | No |
| 6 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 773 | 1.699 | 0.0984 | No |
| 7 | ZSCAN22 | zinc finger and SCAN domain containing 22 [Source:HGNC Symbol;Acc:HGNC:4929] | 805 | 1.657 | 0.1092 | No |
| 8 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 1187 | 1.337 | 0.1083 | No |
| 9 | ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864] | 1811 | 1.012 | 0.0986 | No |
| 10 | MDM2 | MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973] | 1859 | 0.994 | 0.1043 | No |
| 11 | PRKAB1 | protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378] | 1955 | 0.958 | 0.1085 | No |
| 12 | TGM1 | transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777] | 2090 | 0.898 | 0.1111 | No |
| 13 | SLC7A7 | solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065] | 2459 | 0.778 | 0.1067 | No |
| 14 | MAN1B1 | mannosidase alpha class 1B member 1 [Source:HGNC Symbol;Acc:HGNC:6823] | 3045 | 0.621 | 0.0952 | No |
| 15 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 4764 | 0.285 | 0.0507 | No |
| 16 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 4956 | 0.250 | 0.0473 | No |
| 17 | PRKCE | protein kinase C epsilon [Source:HGNC Symbol;Acc:HGNC:9401] | 5291 | 0.194 | 0.0397 | No |
| 18 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 5883 | 0.110 | 0.0244 | No |
| 19 | POLD4 | DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106] | 6264 | 0.047 | 0.0145 | No |
| 20 | FXYD6 | FXYD domain containing ion transport regulator 6 [Source:HGNC Symbol;Acc:HGNC:4030] | 6875 | 0.000 | -0.0020 | No |
| 21 | HES1 | hes family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5192] | 7415 | 0.000 | -0.0166 | No |
| 22 | HEY2 | hes related family bHLH transcription factor with YRPW motif 2 [Source:HGNC Symbol;Acc:HGNC:4881] | 7516 | 0.000 | -0.0193 | No |
| 23 | ARTN | artemin [Source:HGNC Symbol;Acc:HGNC:727] | 7697 | 0.000 | -0.0241 | No |
| 24 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 9054 | 0.000 | -0.0608 | No |
| 25 | TNFRSF18 | TNF receptor superfamily member 18 [Source:HGNC Symbol;Acc:HGNC:11914] | 9444 | 0.000 | -0.0713 | No |
| 26 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 10041 | 0.000 | -0.0875 | No |
| 27 | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin [Source:HGNC Symbol;Acc:HGNC:9016] | 10043 | 0.000 | -0.0875 | No |
| 28 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 10142 | 0.000 | -0.0901 | No |
| 29 | OVOL2 | ovo like zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:15804] | 10884 | 0.000 | -0.1102 | No |
| 30 | LYNX1 | Ly6/neurotoxin 1 [Source:HGNC Symbol;Acc:HGNC:29604] | 11684 | 0.000 | -0.1318 | No |
| 31 | SLC24A1 | solute carrier family 24 member 1 [Source:HGNC Symbol;Acc:HGNC:10975] | 11952 | 0.000 | -0.1390 | No |
| 32 | IL36RN | interleukin 36 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:15561] | 12674 | 0.000 | -0.1585 | No |
| 33 | DDIT4L | DNA damage inducible transcript 4 like [Source:HGNC Symbol;Acc:HGNC:30555] | 13555 | 0.000 | -0.1823 | No |
| 34 | MANSC1 | MANSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25505] | 14039 | 0.000 | -0.1954 | No |
| 35 | PCDH10 | protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404] | 14752 | 0.000 | -0.2146 | No |
| 36 | NOXO1 | NADPH oxidase organizer 1 [Source:HGNC Symbol;Acc:HGNC:19404] | 15525 | 0.000 | -0.2355 | No |
| 37 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16100 | 0.000 | -0.2510 | No |
| 38 | PALMD | palmdelphin [Source:HGNC Symbol;Acc:HGNC:15846] | 16753 | 0.000 | -0.2687 | No |
| 39 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 17121 | 0.000 | -0.2786 | No |
| 40 | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [Source:HGNC Symbol;Acc:HGNC:11097] | 19775 | 0.000 | -0.3504 | No |
| 41 | TMEM54 | transmembrane protein 54 [Source:HGNC Symbol;Acc:HGNC:24143] | 20264 | 0.000 | -0.3635 | No |
| 42 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21993 | 0.000 | -0.4103 | No |
| 43 | SFRP1 | secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] | 23808 | 0.000 | -0.4593 | No |
| 44 | SNAP25 | synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132] | 24364 | 0.000 | -0.4744 | No |
| 45 | ALPK3 | alpha kinase 3 [Source:HGNC Symbol;Acc:HGNC:17574] | 25257 | 0.000 | -0.4985 | No |
| 46 | DUOXA1 | dual oxidase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:26507] | 26185 | 0.000 | -0.5236 | No |
| 47 | UCK1 | uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859] | 28103 | -0.047 | -0.5751 | No |
| 48 | MRPL49 | mitochondrial ribosomal protein L49 [Source:HGNC Symbol;Acc:HGNC:1176] | 28676 | -0.129 | -0.5896 | No |
| 49 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 28835 | -0.148 | -0.5929 | No |
| 50 | DNASE1L1 | deoxyribonuclease 1 like 1 [Source:HGNC Symbol;Acc:HGNC:2957] | 29704 | -0.274 | -0.6144 | No |
| 51 | NUDT5 | nudix hydrolase 5 [Source:HGNC Symbol;Acc:HGNC:8052] | 29859 | -0.297 | -0.6165 | No |
| 52 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30070 | -0.326 | -0.6199 | No |
| 53 | AHCY | adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343] | 30166 | -0.336 | -0.6201 | No |
| 54 | MAPK13 | mitogen-activated protein kinase 13 [Source:HGNC Symbol;Acc:HGNC:6875] | 30532 | -0.389 | -0.6272 | No |
| 55 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 30551 | -0.393 | -0.6250 | No |
| 56 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 31457 | -0.537 | -0.6457 | No |
| 57 | BAZ1B | bromodomain adjacent to zinc finger domain 1B [Source:HGNC Symbol;Acc:HGNC:961] | 31659 | -0.571 | -0.6471 | No |
| 58 | ZW10 | zw10 kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13194] | 31845 | -0.605 | -0.6478 | No |
| 59 | PLEKHA6 | pleckstrin homology domain containing A6 [Source:HGNC Symbol;Acc:HGNC:17053] | 32052 | -0.651 | -0.6488 | No |
| 60 | EI24 | EI24 autophagy associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:13276] | 32101 | -0.663 | -0.6455 | No |
| 61 | NANS | N-acetylneuraminate synthase [Source:HGNC Symbol;Acc:HGNC:19237] | 32263 | -0.696 | -0.6449 | No |
| 62 | TIPIN | TIMELESS interacting protein [Source:HGNC Symbol;Acc:HGNC:30750] | 32406 | -0.721 | -0.6437 | No |
| 63 | AAAS | aladin WD repeat nucleoporin [Source:HGNC Symbol;Acc:HGNC:13666] | 32892 | -0.845 | -0.6509 | Yes |
| 64 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 32931 | -0.855 | -0.6459 | Yes |
| 65 | CTDSP1 | CTD small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614] | 33086 | -0.893 | -0.6438 | Yes |
| 66 | PDXP | pyridoxal phosphatase [Source:HGNC Symbol;Acc:HGNC:30259] | 33152 | -0.914 | -0.6391 | Yes |
| 67 | PCBP2 | poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648] | 33290 | -0.955 | -0.6361 | Yes |
| 68 | LCMT1 | leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557] | 33293 | -0.956 | -0.6294 | Yes |
| 69 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 33618 | -1.054 | -0.6308 | Yes |
| 70 | TKFC | triokinase and FMN cyclase [Source:HGNC Symbol;Acc:HGNC:24552] | 33624 | -1.055 | -0.6235 | Yes |
| 71 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33690 | -1.077 | -0.6177 | Yes |
| 72 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33721 | -1.084 | -0.6109 | Yes |
| 73 | IFT27 | intraflagellar transport 27 [Source:HGNC Symbol;Acc:HGNC:18626] | 33868 | -1.135 | -0.6069 | Yes |
| 74 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 33960 | -1.171 | -0.6011 | Yes |
| 75 | SULF2 | sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392] | 34067 | -1.204 | -0.5955 | Yes |
| 76 | TIMELESS | timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813] | 34130 | -1.218 | -0.5886 | Yes |
| 77 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 34234 | -1.257 | -0.5826 | Yes |
| 78 | MMGT1 | membrane magnesium transporter 1 [Source:HGNC Symbol;Acc:HGNC:28100] | 34395 | -1.316 | -0.5776 | Yes |
| 79 | GNB1L | G protein subunit beta 1 like [Source:HGNC Symbol;Acc:HGNC:4397] | 34804 | -1.463 | -0.5784 | Yes |
| 80 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 34816 | -1.469 | -0.5684 | Yes |
| 81 | STUB1 | STIP1 homology and U-box containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11427] | 34886 | -1.504 | -0.5596 | Yes |
| 82 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 34998 | -1.564 | -0.5517 | Yes |
| 83 | VPS16 | VPS16 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14584] | 35110 | -1.632 | -0.5432 | Yes |
| 84 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 35227 | -1.689 | -0.5345 | Yes |
| 85 | PLXNB2 | plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104] | 35277 | -1.718 | -0.5237 | Yes |
| 86 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 35307 | -1.734 | -0.5123 | Yes |
| 87 | PMS2 | PMS1 homolog 2, mismatch repair system component [Source:HGNC Symbol;Acc:HGNC:9122] | 35327 | -1.743 | -0.5006 | Yes |
| 88 | ZFP30 | ZFP30 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:29555] | 35380 | -1.765 | -0.4896 | Yes |
| 89 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35508 | -1.842 | -0.4801 | Yes |
| 90 | SLC2A9 | solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446] | 35546 | -1.865 | -0.4679 | Yes |
| 91 | PPM1M | protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506] | 35581 | -1.889 | -0.4556 | Yes |
| 92 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 35626 | -1.922 | -0.4433 | Yes |
| 93 | EPHX1 | epoxide hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3401] | 35734 | -2.006 | -0.4321 | Yes |
| 94 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35736 | -2.006 | -0.4180 | Yes |
| 95 | RAD51C | RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820] | 35799 | -2.059 | -0.4052 | Yes |
| 96 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 35868 | -2.107 | -0.3922 | Yes |
| 97 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 35882 | -2.115 | -0.3777 | Yes |
| 98 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36012 | -2.211 | -0.3656 | Yes |
| 99 | TPRA1 | transmembrane protein adipocyte associated 1 [Source:HGNC Symbol;Acc:HGNC:30413] | 36108 | -2.286 | -0.3522 | Yes |
| 100 | NME4 | NME/NM23 nucleoside diphosphate kinase 4 [Source:HGNC Symbol;Acc:HGNC:7852] | 36138 | -2.314 | -0.3367 | Yes |
| 101 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36191 | -2.357 | -0.3215 | Yes |
| 102 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36196 | -2.360 | -0.3050 | Yes |
| 103 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36284 | -2.451 | -0.2901 | Yes |
| 104 | THRA | thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796] | 36497 | -2.709 | -0.2768 | Yes |
| 105 | MSH6 | mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329] | 36544 | -2.786 | -0.2585 | Yes |
| 106 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36546 | -2.789 | -0.2389 | Yes |
| 107 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 36586 | -2.867 | -0.2198 | Yes |
| 108 | GANC | glucosidase alpha, neutral C [Source:HGNC Symbol;Acc:HGNC:4139] | 36663 | -2.967 | -0.2010 | Yes |
| 109 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36679 | -3.000 | -0.1803 | Yes |
| 110 | SPICE1 | spindle and centriole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:25083] | 36701 | -3.055 | -0.1594 | Yes |
| 111 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36736 | -3.113 | -0.1385 | Yes |
| 112 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36757 | -3.180 | -0.1167 | Yes |
| 113 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36789 | -3.243 | -0.0947 | Yes |
| 114 | NUMBL | NUMB like endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8061] | 36881 | -3.501 | -0.0726 | Yes |
| 115 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36884 | -3.527 | -0.0478 | Yes |
| 116 | PMM1 | phosphomannomutase 1 [Source:HGNC Symbol;Acc:HGNC:9114] | 36951 | -3.783 | -0.0230 | Yes |
| 117 | SLC2A8 | solute carrier family 2 member 8 [Source:HGNC Symbol;Acc:HGNC:13812] | 36959 | -3.803 | 0.0035 | Yes |
