Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | RB_P107_DN.V1_UP |
| Enrichment Score (ES) | -0.7362997 |
| Normalized Enrichment Score (NES) | -1.5962342 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0026549972 |
| FWER p-Value | 0.003 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 211 | 2.870 | 0.0129 | No |
| 2 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 212 | 2.863 | 0.0315 | No |
| 3 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 626 | 1.880 | 0.0325 | No |
| 4 | SPIRE2 | spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623] | 1139 | 1.372 | 0.0275 | No |
| 5 | TRPV2 | transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082] | 1256 | 1.294 | 0.0328 | No |
| 6 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 1493 | 1.158 | 0.0339 | No |
| 7 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 1909 | 0.973 | 0.0290 | No |
| 8 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 2866 | 0.664 | 0.0074 | No |
| 9 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 3286 | 0.563 | -0.0003 | No |
| 10 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 3663 | 0.479 | -0.0073 | No |
| 11 | TSSC4 | tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386] | 4657 | 0.303 | -0.0323 | No |
| 12 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 4764 | 0.285 | -0.0333 | No |
| 13 | TCFL5 | transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646] | 4911 | 0.258 | -0.0355 | No |
| 14 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 4956 | 0.250 | -0.0351 | No |
| 15 | H1-10 | H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722] | 5413 | 0.176 | -0.0463 | No |
| 16 | TEK | TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724] | 5800 | 0.124 | -0.0560 | No |
| 17 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 6108 | 0.077 | -0.0638 | No |
| 18 | CES5A | carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459] | 6933 | 0.000 | -0.0861 | No |
| 19 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 8327 | 0.000 | -0.1237 | No |
| 20 | CDH2 | cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759] | 9632 | 0.000 | -0.1590 | No |
| 21 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9845 | 0.000 | -0.1648 | No |
| 22 | KCNA1 | potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218] | 9885 | 0.000 | -0.1658 | No |
| 23 | ABAT | 4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23] | 10724 | 0.000 | -0.1885 | No |
| 24 | FBLN2 | fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601] | 11436 | 0.000 | -0.2077 | No |
| 25 | LYPD1 | LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] | 12194 | 0.000 | -0.2282 | No |
| 26 | BICC1 | BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351] | 12566 | 0.000 | -0.2382 | No |
| 27 | SLIT3 | slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087] | 12715 | 0.000 | -0.2422 | No |
| 28 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12757 | 0.000 | -0.2434 | No |
| 29 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 13025 | 0.000 | -0.2506 | No |
| 30 | TMEM119 | transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884] | 13626 | 0.000 | -0.2668 | No |
| 31 | TMEM45B | transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194] | 14903 | 0.000 | -0.3013 | No |
| 32 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16100 | 0.000 | -0.3337 | No |
| 33 | SI | sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856] | 16324 | 0.000 | -0.3397 | No |
| 34 | EFS | embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898] | 16396 | 0.000 | -0.3416 | No |
| 35 | COL16A1 | collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193] | 16537 | 0.000 | -0.3454 | No |
| 36 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 16635 | 0.000 | -0.3481 | No |
| 37 | SRPX2 | sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668] | 17571 | 0.000 | -0.3734 | No |
| 38 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 18753 | 0.000 | -0.4053 | No |
| 39 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 18754 | 0.000 | -0.4053 | No |
| 40 | FKBP10 | FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169] | 19013 | 0.000 | -0.4123 | No |
| 41 | KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117] | 19682 | 0.000 | -0.4304 | No |
| 42 | LOXL1 | lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665] | 19822 | 0.000 | -0.4341 | No |
| 43 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 20384 | 0.000 | -0.4493 | No |
| 44 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 21238 | 0.000 | -0.4724 | No |
| 45 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21471 | 0.000 | -0.4787 | No |
| 46 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 21993 | 0.000 | -0.4928 | No |
| 47 | RBPMS2 | RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098] | 22580 | 0.000 | -0.5086 | No |
| 48 | COX6B2 | cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] | 24525 | 0.000 | -0.5612 | No |
| 49 | SNCG | synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141] | 25958 | 0.000 | -0.5999 | No |
| 50 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 27938 | -0.026 | -0.6533 | No |
| 51 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 27963 | -0.029 | -0.6538 | No |
| 52 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845] | 28240 | -0.069 | -0.6608 | No |
| 53 | ANAPC11 | anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452] | 28601 | -0.118 | -0.6698 | No |
| 54 | BLVRB | biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063] | 28868 | -0.153 | -0.6760 | No |
| 55 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 29157 | -0.193 | -0.6825 | No |
| 56 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 29242 | -0.208 | -0.6835 | No |
| 57 | DYNLT1 | dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697] | 29513 | -0.243 | -0.6892 | No |
| 58 | MRGPRF | MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828] | 29902 | -0.305 | -0.6977 | No |
| 59 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30070 | -0.326 | -0.7001 | No |
| 60 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 30125 | -0.333 | -0.6994 | No |
| 61 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 30452 | -0.375 | -0.7058 | No |
| 62 | SAMD10 | sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129] | 30462 | -0.376 | -0.7036 | No |
| 63 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 30805 | -0.432 | -0.7101 | No |
| 64 | IPO9 | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] | 30912 | -0.450 | -0.7100 | No |
| 65 | BGN | biglycan [Source:HGNC Symbol;Acc:HGNC:1044] | 31120 | -0.480 | -0.7125 | No |
| 66 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31269 | -0.505 | -0.7132 | No |
| 67 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 31457 | -0.537 | -0.7148 | No |
| 68 | FBLN5 | fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602] | 31824 | -0.601 | -0.7208 | No |
| 69 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 31836 | -0.604 | -0.7172 | No |
| 70 | CDH11 | cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750] | 31915 | -0.619 | -0.7153 | No |
| 71 | NELFE | negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974] | 32074 | -0.657 | -0.7153 | No |
| 72 | PIDD1 | p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491] | 32457 | -0.734 | -0.7209 | No |
| 73 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 32935 | -0.856 | -0.7282 | No |
| 74 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 33186 | -0.925 | -0.7290 | No |
| 75 | TRPM1 | transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146] | 33338 | -0.969 | -0.7268 | No |
| 76 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33690 | -1.077 | -0.7293 | Yes |
| 77 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33721 | -1.084 | -0.7231 | Yes |
| 78 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036] | 33750 | -1.092 | -0.7168 | Yes |
| 79 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 33947 | -1.167 | -0.7145 | Yes |
| 80 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 34077 | -1.206 | -0.7102 | Yes |
| 81 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 34164 | -1.233 | -0.7045 | Yes |
| 82 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 34191 | -1.242 | -0.6972 | Yes |
| 83 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 34234 | -1.257 | -0.6902 | Yes |
| 84 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 34342 | -1.296 | -0.6846 | Yes |
| 85 | DCLRE1A | DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660] | 34703 | -1.428 | -0.6851 | Yes |
| 86 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 34883 | -1.503 | -0.6802 | Yes |
| 87 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 34976 | -1.554 | -0.6726 | Yes |
| 88 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 35016 | -1.575 | -0.6635 | Yes |
| 89 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 35227 | -1.689 | -0.6582 | Yes |
| 90 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 35234 | -1.694 | -0.6474 | Yes |
| 91 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35270 | -1.715 | -0.6372 | Yes |
| 92 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35303 | -1.732 | -0.6269 | Yes |
| 93 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 35304 | -1.732 | -0.6156 | Yes |
| 94 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35455 | -1.811 | -0.6079 | Yes |
| 95 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35508 | -1.842 | -0.5974 | Yes |
| 96 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35527 | -1.854 | -0.5859 | Yes |
| 97 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 35534 | -1.859 | -0.5740 | Yes |
| 98 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35755 | -2.023 | -0.5668 | Yes |
| 99 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35793 | -2.055 | -0.5545 | Yes |
| 100 | HEXD | hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307] | 35821 | -2.071 | -0.5418 | Yes |
| 101 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 35868 | -2.107 | -0.5294 | Yes |
| 102 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 35912 | -2.142 | -0.5167 | Yes |
| 103 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 35916 | -2.145 | -0.5029 | Yes |
| 104 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 36007 | -2.209 | -0.4910 | Yes |
| 105 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36012 | -2.211 | -0.4767 | Yes |
| 106 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36062 | -2.250 | -0.4635 | Yes |
| 107 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36191 | -2.357 | -0.4517 | Yes |
| 108 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36284 | -2.451 | -0.4383 | Yes |
| 109 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36301 | -2.470 | -0.4227 | Yes |
| 110 | RHEBL1 | RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166] | 36355 | -2.534 | -0.4077 | Yes |
| 111 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 36418 | -2.602 | -0.3925 | Yes |
| 112 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36454 | -2.651 | -0.3763 | Yes |
| 113 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 36503 | -2.718 | -0.3599 | Yes |
| 114 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36546 | -2.789 | -0.3430 | Yes |
| 115 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36622 | -2.908 | -0.3262 | Yes |
| 116 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36627 | -2.912 | -0.3074 | Yes |
| 117 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36649 | -2.950 | -0.2888 | Yes |
| 118 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36679 | -3.000 | -0.2702 | Yes |
| 119 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36773 | -3.200 | -0.2520 | Yes |
| 120 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36787 | -3.234 | -0.2313 | Yes |
| 121 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36789 | -3.243 | -0.2103 | Yes |
| 122 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36875 | -3.491 | -0.1900 | Yes |
| 123 | PAQR4 | progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386] | 36876 | -3.491 | -0.1674 | Yes |
| 124 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36884 | -3.527 | -0.1447 | Yes |
| 125 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 36899 | -3.571 | -0.1219 | Yes |
| 126 | TCF19 | transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629] | 36957 | -3.797 | -0.0989 | Yes |
| 127 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 36978 | -3.860 | -0.0744 | Yes |
| 128 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36988 | -3.904 | -0.0493 | Yes |
| 129 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 37003 | -3.998 | -0.0238 | Yes |
| 130 | VEGFB | vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681] | 37009 | -4.025 | 0.0022 | Yes |
