Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | DESCARTES_FETAL_HEART_SMOOTH_MUSCLE_CELLS |
| Enrichment Score (ES) | 0.74166995 |
| Normalized Enrichment Score (NES) | 1.6324078 |
| Nominal p-value | 0.004166667 |
| FDR q-value | 0.047236662 |
| FWER p-Value | 0.232 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | KCNAB1 | potassium voltage-gated channel subfamily A member regulatory beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:6228] | 45 | 4.161 | 0.1929 | Yes |
| 2 | RGS16 | regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997] | 79 | 3.667 | 0.3631 | Yes |
| 3 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 212 | 2.863 | 0.4931 | Yes |
| 4 | ACTA2 | actin alpha 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:130] | 280 | 2.638 | 0.6144 | Yes |
| 5 | PDE4C | phosphodiesterase 4C [Source:HGNC Symbol;Acc:HGNC:8782] | 1583 | 1.127 | 0.6318 | Yes |
| 6 | MYH11 | myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569] | 1985 | 0.945 | 0.6651 | Yes |
| 7 | AOC3 | amine oxidase copper containing 3 [Source:HGNC Symbol;Acc:HGNC:550] | 2126 | 0.887 | 0.7027 | Yes |
| 8 | THBS4 | thrombospondin 4 [Source:HGNC Symbol;Acc:HGNC:11788] | 2183 | 0.869 | 0.7417 | Yes |
| 9 | PLA2G5 | phospholipase A2 group V [Source:HGNC Symbol;Acc:HGNC:9038] | 4616 | 0.310 | 0.6905 | No |
| 10 | ACTA2-AS1 | ACTA2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:45169] | 7794 | 0.000 | 0.6047 | No |
| 11 | TBX2-AS1 | TBX2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50355] | 8362 | 0.000 | 0.5894 | No |
| 12 | MDFIC2 | MyoD family inhibitor domain containing 2 [Source:HGNC Symbol;Acc:HGNC:53442] | 8521 | 0.000 | 0.5852 | No |
| 13 | SEPTIN4-AS1 | SEPTIN4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51345] | 9040 | 0.000 | 0.5712 | No |
| 14 | KCNJ8 | potassium inwardly rectifying channel subfamily J member 8 [Source:HGNC Symbol;Acc:HGNC:6269] | 10012 | 0.000 | 0.5450 | No |
| 15 | APOL5 | apolipoprotein L5 [Source:HGNC Symbol;Acc:HGNC:14869] | 10241 | 0.000 | 0.5388 | No |
| 16 | HIGD1B | HIG1 hypoxia inducible domain family member 1B [Source:HGNC Symbol;Acc:HGNC:24318] | 11206 | 0.000 | 0.5128 | No |
| 17 | LGR6 | leucine rich repeat containing G protein-coupled receptor 6 [Source:HGNC Symbol;Acc:HGNC:19719] | 12260 | 0.000 | 0.4844 | No |
| 18 | ILDR1 | immunoglobulin like domain containing receptor 1 [Source:HGNC Symbol;Acc:HGNC:28741] | 13414 | 0.000 | 0.4532 | No |
| 19 | LINC02237 | long intergenic non-protein coding RNA 2237 [Source:HGNC Symbol;Acc:HGNC:53108] | 13924 | 0.000 | 0.4395 | No |
| 20 | ADRA1D | adrenoceptor alpha 1D [Source:HGNC Symbol;Acc:HGNC:280] | 16570 | 0.000 | 0.3681 | No |
| 21 | GPR20 | G protein-coupled receptor 20 [Source:HGNC Symbol;Acc:HGNC:4475] | 17545 | 0.000 | 0.3418 | No |
| 22 | SEMA5B | semaphorin 5B [Source:HGNC Symbol;Acc:HGNC:10737] | 17873 | 0.000 | 0.3330 | No |
| 23 | HCG22 | HLA complex group 22 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:27780] | 18559 | 0.000 | 0.3145 | No |
| 24 | TMEM74B | transmembrane protein 74B [Source:HGNC Symbol;Acc:HGNC:15893] | 18645 | 0.000 | 0.3122 | No |
| 25 | LMOD1 | leiomodin 1 [Source:HGNC Symbol;Acc:HGNC:6647] | 19478 | 0.000 | 0.2897 | No |
| 26 | FOXS1 | forkhead box S1 [Source:HGNC Symbol;Acc:HGNC:3735] | 23640 | 0.000 | 0.1774 | No |
| 27 | FOXL1 | forkhead box L1 [Source:HGNC Symbol;Acc:HGNC:3817] | 23764 | 0.000 | 0.1741 | No |
| 28 | SULT1E1 | sulfotransferase family 1E member 1 [Source:HGNC Symbol;Acc:HGNC:11377] | 24303 | 0.000 | 0.1596 | No |
| 29 | MYO3A | myosin IIIA [Source:HGNC Symbol;Acc:HGNC:7601] | 24389 | 0.000 | 0.1573 | No |
| 30 | OR51E1 | olfactory receptor family 51 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:15194] | 24633 | 0.000 | 0.1507 | No |
| 31 | C11orf96 | chromosome 11 open reading frame 96 [Source:HGNC Symbol;Acc:HGNC:38675] | 25466 | 0.000 | 0.1283 | No |
| 32 | CCDC190 | coiled-coil domain containing 190 [Source:HGNC Symbol;Acc:HGNC:28736] | 26237 | 0.000 | 0.1075 | No |
| 33 | CARMN | cardiac mesoderm enhancer-associated non-coding RNA [Source:HGNC Symbol;Acc:HGNC:42872] | 26802 | 0.000 | 0.0923 | No |
| 34 | AGT | angiotensinogen [Source:HGNC Symbol;Acc:HGNC:333] | 27432 | 0.000 | 0.0753 | No |
| 35 | ABCC9 | ATP binding cassette subfamily C member 9 [Source:HGNC Symbol;Acc:HGNC:60] | 27763 | 0.000 | 0.0664 | No |
| 36 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 28082 | -0.044 | 0.0599 | No |
| 37 | PDGFRB | platelet derived growth factor receptor beta [Source:HGNC Symbol;Acc:HGNC:8804] | 28565 | -0.112 | 0.0521 | No |
| 38 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 29242 | -0.208 | 0.0435 | No |
| 39 | CYGB | cytoglobin [Source:HGNC Symbol;Acc:HGNC:16505] | 30145 | -0.335 | 0.0348 | No |
| 40 | NDUFA4L2 | NDUFA4 mitochondrial complex associated like 2 [Source:HGNC Symbol;Acc:HGNC:29836] | 30388 | -0.367 | 0.0454 | No |
| 41 | NOTCH3 | notch receptor 3 [Source:HGNC Symbol;Acc:HGNC:7883] | 30465 | -0.377 | 0.0609 | No |
| 42 | CACNA1S | calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397] | 31681 | -0.574 | 0.0549 | No |
| 43 | ARHGEF17 | Rho guanine nucleotide exchange factor 17 [Source:HGNC Symbol;Acc:HGNC:21726] | 33229 | -0.940 | 0.0571 | No |
| 44 | COX4I2 | cytochrome c oxidase subunit 4I2 [Source:HGNC Symbol;Acc:HGNC:16232] | 33470 | -1.010 | 0.0977 | No |
