Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | TRAVAGLINI_LUNG_NATURAL_KILLER_T_CELL |
| Enrichment Score (ES) | 0.7816772 |
| Normalized Enrichment Score (NES) | 1.6448987 |
| Nominal p-value | 0.004032258 |
| FDR q-value | 0.04358053 |
| FWER p-Value | 0.202 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 16 | 4.622 | 0.2903 | Yes |
| 2 | ID2 | inhibitor of DNA binding 2 [Source:HGNC Symbol;Acc:HGNC:5361] | 335 | 2.420 | 0.4340 | Yes |
| 3 | SOCS1 | suppressor of cytokine signaling 1 [Source:HGNC Symbol;Acc:HGNC:19383] | 373 | 2.309 | 0.5782 | Yes |
| 4 | RGS1 | regulator of G protein signaling 1 [Source:HGNC Symbol;Acc:HGNC:9991] | 469 | 2.127 | 0.7094 | Yes |
| 5 | MYL12A | myosin light chain 12A [Source:HGNC Symbol;Acc:HGNC:16701] | 1080 | 1.410 | 0.7817 | Yes |
| 6 | CRTAM | cytotoxic and regulatory T cell molecule [Source:HGNC Symbol;Acc:HGNC:24313] | 4131 | 0.394 | 0.7241 | No |
| 7 | B2M | beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914] | 4750 | 0.288 | 0.7256 | No |
| 8 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 6146 | 0.071 | 0.6924 | No |
| 9 | SLA2 | Src like adaptor 2 [Source:HGNC Symbol;Acc:HGNC:17329] | 9348 | 0.000 | 0.6060 | No |
| 10 | TNFRSF18 | TNF receptor superfamily member 18 [Source:HGNC Symbol;Acc:HGNC:11914] | 9444 | 0.000 | 0.6035 | No |
| 11 | NKG7 | natural killer cell granule protein 7 [Source:HGNC Symbol;Acc:HGNC:7830] | 11447 | 0.000 | 0.5494 | No |
| 12 | PRF1 | perforin 1 [Source:HGNC Symbol;Acc:HGNC:9360] | 11647 | 0.000 | 0.5441 | No |
| 13 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12324 | 0.000 | 0.5258 | No |
| 14 | IL2RB | interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009] | 15705 | 0.000 | 0.4346 | No |
| 15 | CD7 | CD7 molecule [Source:HGNC Symbol;Acc:HGNC:1695] | 15833 | 0.000 | 0.4312 | No |
| 16 | XCL2 | X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10646] | 15939 | 0.000 | 0.4283 | No |
| 17 | XCL1 | X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645] | 15941 | 0.000 | 0.4283 | No |
| 18 | SH2D1B | SH2 domain containing 1B [Source:HGNC Symbol;Acc:HGNC:30416] | 15986 | 0.000 | 0.4271 | No |
| 19 | XIST | X inactive specific transcript [Source:HGNC Symbol;Acc:HGNC:12810] | 17886 | 0.000 | 0.3759 | No |
| 20 | ZNF683 | zinc finger protein 683 [Source:HGNC Symbol;Acc:HGNC:28495] | 21507 | 0.000 | 0.2782 | No |
| 21 | KRT81 | keratin 81 [Source:HGNC Symbol;Acc:HGNC:6458] | 22182 | 0.000 | 0.2600 | No |
| 22 | KRT86 | keratin 86 [Source:HGNC Symbol;Acc:HGNC:6463] | 22187 | 0.000 | 0.2599 | No |
| 23 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22575 | 0.000 | 0.2495 | No |
| 24 | CD69 | CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694] | 23238 | 0.000 | 0.2316 | No |
| 25 | KLRC1 | killer cell lectin like receptor C1 [Source:HGNC Symbol;Acc:HGNC:6374] | 24156 | 0.000 | 0.2068 | No |
| 26 | KLRC2 | killer cell lectin like receptor C2 [Source:HGNC Symbol;Acc:HGNC:6375] | 24157 | 0.000 | 0.2068 | No |
| 27 | KLRC3 | killer cell lectin like receptor C3 [Source:HGNC Symbol;Acc:HGNC:6376] | 24158 | 0.000 | 0.2068 | No |
| 28 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 24162 | 0.000 | 0.2068 | No |
| 29 | CTSW | cathepsin W [Source:HGNC Symbol;Acc:HGNC:2546] | 25272 | 0.000 | 0.1768 | No |
| 30 | HOPX | HOP homeobox [Source:HGNC Symbol;Acc:HGNC:24961] | 26367 | 0.000 | 0.1473 | No |
| 31 | ITGA1 | integrin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6134] | 26705 | 0.000 | 0.1382 | No |
| 32 | GATA3 | GATA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:4172] | 29624 | -0.261 | 0.0759 | No |
| 33 | CXCR3 | C-X-C motif chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:4540] | 32950 | -0.862 | 0.0404 | No |
| 34 | CXCR4 | C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561] | 33862 | -1.133 | 0.0871 | No |
