Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | TRAVAGLINI_LUNG_PROLIFERATING_NK_T_CELL |
| Enrichment Score (ES) | -0.7860441 |
| Normalized Enrichment Score (NES) | -1.7051775 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.15151524E-4 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 16 | 4.622 | 0.0249 | No |
| 2 | RCC1 | regulator of chromosome condensation 1 [Source:HGNC Symbol;Acc:HGNC:1913] | 1492 | 1.158 | -0.0086 | No |
| 3 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1504 | 1.154 | -0.0026 | No |
| 4 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 1909 | 0.973 | -0.0082 | No |
| 5 | PPIA | peptidylprolyl isomerase A [Source:HGNC Symbol;Acc:HGNC:9253] | 2145 | 0.881 | -0.0097 | No |
| 6 | RANBP1 | RAN binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9847] | 2244 | 0.846 | -0.0077 | No |
| 7 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 2617 | 0.727 | -0.0138 | No |
| 8 | SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 [Source:HGNC Symbol;Acc:HGNC:11153] | 3239 | 0.573 | -0.0274 | No |
| 9 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 3663 | 0.479 | -0.0363 | No |
| 10 | PSMC3 | proteasome 26S subunit, ATPase 3 [Source:HGNC Symbol;Acc:HGNC:9549] | 3764 | 0.459 | -0.0364 | No |
| 11 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 4956 | 0.250 | -0.0673 | No |
| 12 | PSMD8 | proteasome 26S subunit, non-ATPase 8 [Source:HGNC Symbol;Acc:HGNC:9566] | 5766 | 0.128 | -0.0885 | No |
| 13 | CD160 | CD160 molecule [Source:HGNC Symbol;Acc:HGNC:17013] | 7956 | 0.000 | -0.1477 | No |
| 14 | C21orf58 | chromosome 21 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:1300] | 10905 | 0.000 | -0.2275 | No |
| 15 | IGFBP7 | insulin like growth factor binding protein 7 [Source:HGNC Symbol;Acc:HGNC:5476] | 11935 | 0.000 | -0.2553 | No |
| 16 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12324 | 0.000 | -0.2658 | No |
| 17 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12619 | 0.000 | -0.2737 | No |
| 18 | C12orf75 | chromosome 12 open reading frame 75 [Source:HGNC Symbol;Acc:HGNC:35164] | 12885 | 0.000 | -0.2809 | No |
| 19 | SH2D1B | SH2 domain containing 1B [Source:HGNC Symbol;Acc:HGNC:30416] | 15986 | 0.000 | -0.3648 | No |
| 20 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 18025 | 0.000 | -0.4199 | No |
| 21 | ICAM2 | intercellular adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:5345] | 18288 | 0.000 | -0.4270 | No |
| 22 | GNLY | granulysin [Source:HGNC Symbol;Acc:HGNC:4414] | 22575 | 0.000 | -0.5430 | No |
| 23 | KLRF1 | killer cell lectin like receptor F1 [Source:HGNC Symbol;Acc:HGNC:13342] | 24139 | 0.000 | -0.5852 | No |
| 24 | HMGN3 | high mobility group nucleosomal binding domain 3 [Source:HGNC Symbol;Acc:HGNC:12312] | 24736 | 0.000 | -0.6014 | No |
| 25 | PRSS23 | serine protease 23 [Source:HGNC Symbol;Acc:HGNC:14370] | 25460 | 0.000 | -0.6209 | No |
| 26 | FGFBP2 | fibroblast growth factor binding protein 2 [Source:HGNC Symbol;Acc:HGNC:29451] | 26037 | 0.000 | -0.6365 | No |
| 27 | CCDC167 | coiled-coil domain containing 167 [Source:HGNC Symbol;Acc:HGNC:21239] | 26173 | 0.000 | -0.6402 | No |
| 28 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26430 | 0.000 | -0.6471 | No |
| 29 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27912 | -0.021 | -0.6870 | No |
| 30 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 27938 | -0.026 | -0.6876 | No |
| 31 | EBP | EBP cholestenol delta-isomerase [Source:HGNC Symbol;Acc:HGNC:3133] | 28608 | -0.119 | -0.7050 | No |
| 32 | SNRNP25 | small nuclear ribonucleoprotein U11/U12 subunit 25 [Source:HGNC Symbol;Acc:HGNC:14161] | 28708 | -0.133 | -0.7070 | No |
| 33 | POLQ | DNA polymerase theta [Source:HGNC Symbol;Acc:HGNC:9186] | 28779 | -0.141 | -0.7081 | No |
| 34 | DCTN3 | dynactin subunit 3 [Source:HGNC Symbol;Acc:HGNC:2713] | 28959 | -0.165 | -0.7120 | No |
| 35 | GGH | gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] | 29206 | -0.201 | -0.7176 | No |
| 36 | LSM5 | LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17162] | 29295 | -0.214 | -0.7188 | No |
| 37 | SKA2 | spindle and kinetochore associated complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:28006] | 29483 | -0.241 | -0.7225 | No |
| 38 | AKR1C3 | aldo-keto reductase family 1 member C3 [Source:HGNC Symbol;Acc:HGNC:386] | 29757 | -0.283 | -0.7283 | No |
| 39 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 30070 | -0.326 | -0.7350 | No |
| 40 | TROAP | trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327] | 30395 | -0.368 | -0.7417 | No |
| 41 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 30452 | -0.375 | -0.7412 | No |
| 42 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31056 | -0.470 | -0.7549 | No |
| 43 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 31158 | -0.486 | -0.7550 | No |
| 44 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 31772 | -0.593 | -0.7683 | No |
| 45 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 31836 | -0.604 | -0.7667 | No |
| 46 | APMAP | adipocyte plasma membrane associated protein [Source:HGNC Symbol;Acc:HGNC:13238] | 32436 | -0.729 | -0.7789 | No |
| 47 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32700 | -0.796 | -0.7817 | Yes |
| 48 | NUCB2 | nucleobindin 2 [Source:HGNC Symbol;Acc:HGNC:8044] | 32773 | -0.817 | -0.7791 | Yes |
| 49 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 32783 | -0.819 | -0.7749 | Yes |
| 50 | HPRT1 | hypoxanthine phosphoribosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:5157] | 33002 | -0.873 | -0.7760 | Yes |
| 51 | SKA3 | spindle and kinetochore associated complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:20262] | 33244 | -0.944 | -0.7773 | Yes |
| 52 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 33267 | -0.949 | -0.7727 | Yes |
| 53 | MND1 | meiotic nuclear divisions 1 [Source:HGNC Symbol;Acc:HGNC:24839] | 33349 | -0.972 | -0.7696 | Yes |
| 54 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33713 | -1.082 | -0.7735 | Yes |
| 55 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 33721 | -1.084 | -0.7677 | Yes |
| 56 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 33947 | -1.167 | -0.7674 | Yes |
| 57 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 33954 | -1.169 | -0.7611 | Yes |
| 58 | ZNF367 | zinc finger protein 367 [Source:HGNC Symbol;Acc:HGNC:18320] | 34053 | -1.200 | -0.7572 | Yes |
| 59 | PXMP2 | peroxisomal membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:9716] | 34121 | -1.215 | -0.7523 | Yes |
| 60 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 34164 | -1.233 | -0.7467 | Yes |
| 61 | H2AZ1 | H2A.Z variant histone 1 [Source:HGNC Symbol;Acc:HGNC:4741] | 34219 | -1.252 | -0.7413 | Yes |
| 62 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 34234 | -1.257 | -0.7348 | Yes |
| 63 | TUBA1B | tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809] | 34314 | -1.283 | -0.7299 | Yes |
| 64 | CDT1 | chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576] | 34470 | -1.342 | -0.7267 | Yes |
| 65 | CDC25C | cell division cycle 25C [Source:HGNC Symbol;Acc:HGNC:1727] | 34490 | -1.349 | -0.7198 | Yes |
| 66 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 34522 | -1.361 | -0.7132 | Yes |
| 67 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34533 | -1.364 | -0.7060 | Yes |
| 68 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 34584 | -1.386 | -0.6997 | Yes |
| 69 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34655 | -1.411 | -0.6939 | Yes |
| 70 | NUDT1 | nudix hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:8048] | 34724 | -1.434 | -0.6879 | Yes |
| 71 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 34826 | -1.475 | -0.6825 | Yes |
| 72 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34896 | -1.510 | -0.6761 | Yes |
| 73 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 34976 | -1.554 | -0.6697 | Yes |
| 74 | ATAD5 | ATPase family AAA domain containing 5 [Source:HGNC Symbol;Acc:HGNC:25752] | 34993 | -1.563 | -0.6615 | Yes |
| 75 | DIAPH3 | diaphanous related formin 3 [Source:HGNC Symbol;Acc:HGNC:15480] | 34999 | -1.564 | -0.6531 | Yes |
| 76 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35012 | -1.573 | -0.6448 | Yes |
| 77 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 35016 | -1.575 | -0.6362 | Yes |
| 78 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35266 | -1.714 | -0.6336 | Yes |
| 79 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35303 | -1.732 | -0.6250 | Yes |
| 80 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 35304 | -1.732 | -0.6155 | Yes |
| 81 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35315 | -1.737 | -0.6063 | Yes |
| 82 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35493 | -1.831 | -0.6010 | Yes |
| 83 | FANCD2 | FA complementation group D2 [Source:HGNC Symbol;Acc:HGNC:3585] | 35542 | -1.863 | -0.5921 | Yes |
| 84 | CENPN | centromere protein N [Source:HGNC Symbol;Acc:HGNC:30873] | 35643 | -1.931 | -0.5842 | Yes |
| 85 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35659 | -1.943 | -0.5739 | Yes |
| 86 | PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 [Source:HGNC Symbol;Acc:HGNC:29650] | 35668 | -1.954 | -0.5634 | Yes |
| 87 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35723 | -1.996 | -0.5539 | Yes |
| 88 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35732 | -2.004 | -0.5431 | Yes |
| 89 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35736 | -2.006 | -0.5322 | Yes |
| 90 | HELLS | helicase, lymphoid specific [Source:HGNC Symbol;Acc:HGNC:4861] | 35750 | -2.017 | -0.5215 | Yes |
| 91 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35755 | -2.023 | -0.5105 | Yes |
| 92 | CENPU | centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348] | 35816 | -2.070 | -0.5008 | Yes |
| 93 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35889 | -2.122 | -0.4911 | Yes |
| 94 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35922 | -2.150 | -0.4801 | Yes |
| 95 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35935 | -2.155 | -0.4686 | Yes |
| 96 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.4573 | Yes |
| 97 | IDH2 | isocitrate dehydrogenase (NADP(+)) 2 [Source:HGNC Symbol;Acc:HGNC:5383] | 35984 | -2.196 | -0.4459 | Yes |
| 98 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36012 | -2.211 | -0.4345 | Yes |
| 99 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36015 | -2.212 | -0.4224 | Yes |
| 100 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36049 | -2.239 | -0.4110 | Yes |
| 101 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36062 | -2.250 | -0.3990 | Yes |
| 102 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36186 | -2.355 | -0.3894 | Yes |
| 103 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36191 | -2.357 | -0.3766 | Yes |
| 104 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36232 | -2.394 | -0.3645 | Yes |
| 105 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36238 | -2.399 | -0.3515 | Yes |
| 106 | CLSPN | claspin [Source:HGNC Symbol;Acc:HGNC:19715] | 36240 | -2.401 | -0.3383 | Yes |
| 107 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36286 | -2.451 | -0.3261 | Yes |
| 108 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36289 | -2.458 | -0.3127 | Yes |
| 109 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36301 | -2.470 | -0.2994 | Yes |
| 110 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36360 | -2.539 | -0.2871 | Yes |
| 111 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 36383 | -2.566 | -0.2736 | Yes |
| 112 | ATAD2 | ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123] | 36387 | -2.570 | -0.2596 | Yes |
| 113 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 36458 | -2.656 | -0.2469 | Yes |
| 114 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36546 | -2.789 | -0.2339 | Yes |
| 115 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36562 | -2.813 | -0.2189 | Yes |
| 116 | BRCA2 | BRCA2 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1101] | 36585 | -2.864 | -0.2038 | Yes |
| 117 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36620 | -2.903 | -0.1888 | Yes |
| 118 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36643 | -2.941 | -0.1732 | Yes |
| 119 | TMEM106C | transmembrane protein 106C [Source:HGNC Symbol;Acc:HGNC:28775] | 36653 | -2.952 | -0.1573 | Yes |
| 120 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36679 | -3.000 | -0.1415 | Yes |
| 121 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36747 | -3.148 | -0.1260 | Yes |
| 122 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36757 | -3.180 | -0.1088 | Yes |
| 123 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36773 | -3.200 | -0.0917 | Yes |
| 124 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36787 | -3.234 | -0.0743 | Yes |
| 125 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 36858 | -3.461 | -0.0572 | Yes |
| 126 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36872 | -3.490 | -0.0384 | Yes |
| 127 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36988 | -3.904 | -0.0201 | Yes |
| 128 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37029 | -4.153 | 0.0017 | Yes |
