Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | ZHONG_PFC_C2_UNKNOWN_NPC |
| Enrichment Score (ES) | -0.839029 |
| Normalized Enrichment Score (NES) | -1.7257406 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.6121214E-4 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1504 | 1.154 | -0.0306 | No |
| 2 | TUBB6 | tubulin beta 6 class V [Source:HGNC Symbol;Acc:HGNC:20776] | 3401 | 0.536 | -0.0771 | No |
| 3 | CNOT7 | CCR4-NOT transcription complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:14101] | 4375 | 0.348 | -0.1004 | No |
| 4 | KDM4A | lysine demethylase 4A [Source:HGNC Symbol;Acc:HGNC:22978] | 4887 | 0.261 | -0.1119 | No |
| 5 | CALB2 | calbindin 2 [Source:HGNC Symbol;Acc:HGNC:1435] | 8967 | 0.000 | -0.2221 | No |
| 6 | AC091057.1 | OTU deubiquitinase 7A pseudogene [Source:NCBI gene (formerly Entrezgene);Acc:100288637] | 12949 | 0.000 | -0.3296 | No |
| 7 | NDST4 | N-deacetylase and N-sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:20779] | 13668 | 0.000 | -0.3490 | No |
| 8 | DNALI1 | dynein axonemal light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:14353] | 17902 | 0.000 | -0.4634 | No |
| 9 | ZNF649 | zinc finger protein 649 [Source:HGNC Symbol;Acc:HGNC:25741] | 21533 | 0.000 | -0.5615 | No |
| 10 | AMBN | ameloblastin [Source:HGNC Symbol;Acc:HGNC:452] | 24793 | 0.000 | -0.6495 | No |
| 11 | MFAP2 | microfibril associated protein 2 [Source:HGNC Symbol;Acc:HGNC:7033] | 25765 | 0.000 | -0.6757 | No |
| 12 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 27831 | -0.006 | -0.7315 | No |
| 13 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 28646 | -0.123 | -0.7524 | No |
| 14 | ITCH | itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890] | 29305 | -0.216 | -0.7683 | No |
| 15 | PHF19 | PHD finger protein 19 [Source:HGNC Symbol;Acc:HGNC:24566] | 29808 | -0.291 | -0.7793 | No |
| 16 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 30352 | -0.363 | -0.7908 | No |
| 17 | TROAP | trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327] | 30395 | -0.368 | -0.7887 | No |
| 18 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31056 | -0.470 | -0.8024 | No |
| 19 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 32085 | -0.659 | -0.8245 | No |
| 20 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 32625 | -0.776 | -0.8323 | Yes |
| 21 | PIF1 | PIF1 5'-to-3' DNA helicase [Source:HGNC Symbol;Acc:HGNC:26220] | 32670 | -0.788 | -0.8266 | Yes |
| 22 | ARL6IP1 | ADP ribosylation factor like GTPase 6 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:697] | 33076 | -0.891 | -0.8297 | Yes |
| 23 | LDHA | lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535] | 33313 | -0.961 | -0.8277 | Yes |
| 24 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33479 | -1.012 | -0.8233 | Yes |
| 25 | DEPDC1 | DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949] | 33541 | -1.033 | -0.8160 | Yes |
| 26 | ARHGAP11A | Rho GTPase activating protein 11A [Source:HGNC Symbol;Acc:HGNC:15783] | 33648 | -1.063 | -0.8096 | Yes |
| 27 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33713 | -1.082 | -0.8018 | Yes |
| 28 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 33771 | -1.101 | -0.7938 | Yes |
| 29 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 33954 | -1.169 | -0.7885 | Yes |
| 30 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 34164 | -1.233 | -0.7834 | Yes |
| 31 | REEP4 | receptor accessory protein 4 [Source:HGNC Symbol;Acc:HGNC:26176] | 34198 | -1.244 | -0.7734 | Yes |
| 32 | TRIM59 | tripartite motif containing 59 [Source:HGNC Symbol;Acc:HGNC:30834] | 34276 | -1.271 | -0.7644 | Yes |
| 33 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34533 | -1.364 | -0.7594 | Yes |
| 34 | RANGAP1 | Ran GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9854] | 34543 | -1.366 | -0.7477 | Yes |
| 35 | NDE1 | nudE neurodevelopment protein 1 [Source:HGNC Symbol;Acc:HGNC:17619] | 34552 | -1.369 | -0.7360 | Yes |
| 36 | G2E3 | G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338] | 34747 | -1.442 | -0.7286 | Yes |
| 37 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 34826 | -1.475 | -0.7179 | Yes |
| 38 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34860 | -1.492 | -0.7057 | Yes |
| 39 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 34894 | -1.508 | -0.6935 | Yes |
| 40 | CIT | citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985] | 34904 | -1.517 | -0.6805 | Yes |
| 41 | CKAP2L | cytoskeleton associated protein 2 like [Source:HGNC Symbol;Acc:HGNC:26877] | 34930 | -1.530 | -0.6678 | Yes |
| 42 | TUBA1C | tubulin alpha 1c [Source:HGNC Symbol;Acc:HGNC:20768] | 35003 | -1.565 | -0.6561 | Yes |
| 43 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 35028 | -1.585 | -0.6429 | Yes |
| 44 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35165 | -1.659 | -0.6321 | Yes |
| 45 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 35207 | -1.677 | -0.6185 | Yes |
| 46 | FAM83D | family with sequence similarity 83 member D [Source:HGNC Symbol;Acc:HGNC:16122] | 35262 | -1.712 | -0.6051 | Yes |
| 47 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35266 | -1.714 | -0.5902 | Yes |
| 48 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 35307 | -1.734 | -0.5761 | Yes |
| 49 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 35315 | -1.737 | -0.5611 | Yes |
| 50 | MZT1 | mitotic spindle organizing protein 1 [Source:HGNC Symbol;Acc:HGNC:33830] | 35494 | -1.832 | -0.5500 | Yes |
| 51 | CDCA2 | cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623] | 35638 | -1.929 | -0.5370 | Yes |
| 52 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35659 | -1.943 | -0.5206 | Yes |
| 53 | KNSTRN | kinetochore localized astrin (SPAG5) binding protein [Source:HGNC Symbol;Acc:HGNC:30767] | 35720 | -1.992 | -0.5048 | Yes |
| 54 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 35793 | -2.055 | -0.4888 | Yes |
| 55 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 35935 | -2.155 | -0.4738 | Yes |
| 56 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.4554 | Yes |
| 57 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35968 | -2.186 | -0.4365 | Yes |
| 58 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36049 | -2.239 | -0.4191 | Yes |
| 59 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.4002 | Yes |
| 60 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36186 | -2.355 | -0.3825 | Yes |
| 61 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36232 | -2.394 | -0.3628 | Yes |
| 62 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36286 | -2.451 | -0.3428 | Yes |
| 63 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36304 | -2.474 | -0.3217 | Yes |
| 64 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 36311 | -2.482 | -0.3002 | Yes |
| 65 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36326 | -2.499 | -0.2788 | Yes |
| 66 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36454 | -2.651 | -0.2590 | Yes |
| 67 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36519 | -2.751 | -0.2368 | Yes |
| 68 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36555 | -2.800 | -0.2133 | Yes |
| 69 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36562 | -2.813 | -0.1889 | Yes |
| 70 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 36573 | -2.835 | -0.1644 | Yes |
| 71 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36620 | -2.903 | -0.1403 | Yes |
| 72 | MIS18BP1 | MIS18 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20190] | 36694 | -3.042 | -0.1157 | Yes |
| 73 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36747 | -3.148 | -0.0896 | Yes |
| 74 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 36858 | -3.461 | -0.0624 | Yes |
| 75 | NEIL3 | nei like DNA glycosylase 3 [Source:HGNC Symbol;Acc:HGNC:24573] | 36921 | -3.644 | -0.0323 | Yes |
| 76 | PSRC1 | proline and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24472] | 37035 | -4.217 | 0.0015 | Yes |
