Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | ZHONG_PFC_C8_ORG_PROLIFERATING |
| Enrichment Score (ES) | -0.81894207 |
| Normalized Enrichment Score (NES) | -1.649076 |
| Nominal p-value | 0.0 |
| FDR q-value | 5.89974E-4 |
| FWER p-Value | 0.009 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 1504 | 1.154 | -0.0281 | No |
| 2 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 2613 | 0.729 | -0.0501 | No |
| 3 | EMP3 | epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] | 3389 | 0.539 | -0.0652 | No |
| 4 | TUBB6 | tubulin beta 6 class V [Source:HGNC Symbol;Acc:HGNC:20776] | 3401 | 0.536 | -0.0597 | No |
| 5 | NOTCH2NLA | notch 2 N-terminal like A [Source:HGNC Symbol;Acc:HGNC:31862] | 3929 | 0.429 | -0.0693 | No |
| 6 | ITGB1BP1 | integrin subunit beta 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23927] | 5790 | 0.125 | -0.1182 | No |
| 7 | CCNA1 | cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577] | 7782 | 0.000 | -0.1719 | No |
| 8 | NMU | neuromedin U [Source:HGNC Symbol;Acc:HGNC:7859] | 19354 | 0.000 | -0.4844 | No |
| 9 | SFRP2 | secreted frizzled related protein 2 [Source:HGNC Symbol;Acc:HGNC:10777] | 23810 | 0.000 | -0.6047 | No |
| 10 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 24301 | 0.000 | -0.6180 | No |
| 11 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 27831 | -0.006 | -0.7132 | No |
| 12 | GAS2L3 | growth arrest specific 2 like 3 [Source:HGNC Symbol;Acc:HGNC:27475] | 27856 | -0.010 | -0.7137 | No |
| 13 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 28646 | -0.123 | -0.7337 | No |
| 14 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 29798 | -0.290 | -0.7617 | No |
| 15 | UNC50 | unc-50 inner nuclear membrane RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16046] | 30059 | -0.324 | -0.7652 | No |
| 16 | TROAP | trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327] | 30395 | -0.368 | -0.7702 | No |
| 17 | CRNDE | colorectal neoplasia differentially expressed [Source:HGNC Symbol;Acc:HGNC:37078] | 30993 | -0.461 | -0.7813 | No |
| 18 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31056 | -0.470 | -0.7779 | No |
| 19 | TXNDC12 | thioredoxin domain containing 12 [Source:HGNC Symbol;Acc:HGNC:24626] | 32576 | -0.767 | -0.8106 | Yes |
| 20 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 32625 | -0.776 | -0.8035 | Yes |
| 21 | ARL6IP1 | ADP ribosylation factor like GTPase 6 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:697] | 33076 | -0.891 | -0.8060 | Yes |
| 22 | ANXA2 | annexin A2 [Source:HGNC Symbol;Acc:HGNC:537] | 33455 | -1.005 | -0.8053 | Yes |
| 23 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 33479 | -1.012 | -0.7950 | Yes |
| 24 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 33713 | -1.082 | -0.7895 | Yes |
| 25 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 33771 | -1.101 | -0.7791 | Yes |
| 26 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 33954 | -1.169 | -0.7714 | Yes |
| 27 | TMEM256 | transmembrane protein 256 [Source:HGNC Symbol;Acc:HGNC:28618] | 33967 | -1.173 | -0.7590 | Yes |
| 28 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 34533 | -1.364 | -0.7595 | Yes |
| 29 | SMTN | smoothelin [Source:HGNC Symbol;Acc:HGNC:11126] | 34678 | -1.421 | -0.7480 | Yes |
| 30 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34860 | -1.492 | -0.7367 | Yes |
| 31 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 34905 | -1.518 | -0.7214 | Yes |
| 32 | TUBA1C | tubulin alpha 1c [Source:HGNC Symbol;Acc:HGNC:20768] | 35003 | -1.565 | -0.7071 | Yes |
| 33 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35165 | -1.659 | -0.6934 | Yes |
| 34 | PLIN3 | perilipin 3 [Source:HGNC Symbol;Acc:HGNC:16893] | 35220 | -1.686 | -0.6766 | Yes |
| 35 | ODF2 | outer dense fiber of sperm tails 2 [Source:HGNC Symbol;Acc:HGNC:8114] | 35252 | -1.705 | -0.6590 | Yes |
| 36 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35266 | -1.714 | -0.6408 | Yes |
| 37 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 35307 | -1.734 | -0.6230 | Yes |
| 38 | CCDC34 | coiled-coil domain containing 34 [Source:HGNC Symbol;Acc:HGNC:25079] | 35451 | -1.809 | -0.6073 | Yes |
| 39 | MZT1 | mitotic spindle organizing protein 1 [Source:HGNC Symbol;Acc:HGNC:33830] | 35494 | -1.832 | -0.5886 | Yes |
| 40 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 35527 | -1.854 | -0.5693 | Yes |
| 41 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35572 | -1.882 | -0.5501 | Yes |
| 42 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 35645 | -1.933 | -0.5311 | Yes |
| 43 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35659 | -1.943 | -0.5104 | Yes |
| 44 | KNSTRN | kinetochore localized astrin (SPAG5) binding protein [Source:HGNC Symbol;Acc:HGNC:30767] | 35720 | -1.992 | -0.4904 | Yes |
| 45 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 35889 | -2.122 | -0.4720 | Yes |
| 46 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36049 | -2.239 | -0.4520 | Yes |
| 47 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.4283 | Yes |
| 48 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36249 | -2.411 | -0.4067 | Yes |
| 49 | CRYZ | crystallin zeta [Source:HGNC Symbol;Acc:HGNC:2419] | 36259 | -2.425 | -0.3806 | Yes |
| 50 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 36277 | -2.444 | -0.3546 | Yes |
| 51 | DEPDC1B | DEP domain containing 1B [Source:HGNC Symbol;Acc:HGNC:24902] | 36290 | -2.458 | -0.3283 | Yes |
| 52 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36304 | -2.474 | -0.3018 | Yes |
| 53 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 36311 | -2.482 | -0.2751 | Yes |
| 54 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36326 | -2.499 | -0.2484 | Yes |
| 55 | RP2 | RP2 activator of ARL3 GTPase [Source:HGNC Symbol;Acc:HGNC:10274] | 36445 | -2.642 | -0.2229 | Yes |
| 56 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36555 | -2.800 | -0.1955 | Yes |
| 57 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36562 | -2.813 | -0.1652 | Yes |
| 58 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 36573 | -2.835 | -0.1347 | Yes |
| 59 | KIF18A | kinesin family member 18A [Source:HGNC Symbol;Acc:HGNC:29441] | 36602 | -2.881 | -0.1042 | Yes |
| 60 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36747 | -3.148 | -0.0740 | Yes |
| 61 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 36858 | -3.461 | -0.0395 | Yes |
| 62 | PSRC1 | proline and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24472] | 37035 | -4.217 | 0.0015 | Yes |
