Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | HALLMARK_ANGIOGENESIS |
| Enrichment Score (ES) | 0.63593644 |
| Normalized Enrichment Score (NES) | 1.3540087 |
| Nominal p-value | 0.06692913 |
| FDR q-value | 0.06455269 |
| FWER p-Value | 0.118 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 119 | 3.348 | 0.1609 | Yes |
| 2 | ITGAV | integrin subunit alpha V [Source:HGNC Symbol;Acc:HGNC:6150] | 216 | 2.848 | 0.2979 | Yes |
| 3 | CCND2 | cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583] | 348 | 2.377 | 0.4109 | Yes |
| 4 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 449 | 2.164 | 0.5143 | Yes |
| 5 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 717 | 1.768 | 0.5937 | Yes |
| 6 | LPL | lipoprotein lipase [Source:HGNC Symbol;Acc:HGNC:6677] | 1375 | 1.224 | 0.6359 | Yes |
| 7 | PTK2 | protein tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:9611] | 5205 | 0.207 | 0.5428 | No |
| 8 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 5213 | 0.206 | 0.5527 | No |
| 9 | VAV2 | vav guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:12658] | 6287 | 0.044 | 0.5259 | No |
| 10 | APOH | apolipoprotein H [Source:HGNC Symbol;Acc:HGNC:616] | 7050 | 0.000 | 0.5053 | No |
| 11 | FGFR1 | fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688] | 7385 | 0.000 | 0.4963 | No |
| 12 | TNFRSF21 | TNF receptor superfamily member 21 [Source:HGNC Symbol;Acc:HGNC:13469] | 9451 | 0.000 | 0.4406 | No |
| 13 | KCNJ8 | potassium inwardly rectifying channel subfamily J member 8 [Source:HGNC Symbol;Acc:HGNC:6269] | 10012 | 0.000 | 0.4254 | No |
| 14 | POSTN | periostin [Source:HGNC Symbol;Acc:HGNC:16953] | 10424 | 0.000 | 0.4144 | No |
| 15 | PRG2 | proteoglycan 2, pro eosinophil major basic protein [Source:HGNC Symbol;Acc:HGNC:9362] | 11674 | 0.000 | 0.3806 | No |
| 16 | MSX1 | msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391] | 12646 | 0.000 | 0.3544 | No |
| 17 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 12826 | 0.000 | 0.3496 | No |
| 18 | VTN | vitronectin [Source:HGNC Symbol;Acc:HGNC:12724] | 13416 | 0.000 | 0.3337 | No |
| 19 | OLR1 | oxidized low density lipoprotein receptor 1 [Source:HGNC Symbol;Acc:HGNC:8133] | 16791 | 0.000 | 0.2427 | No |
| 20 | SERPINA5 | serpin family A member 5 [Source:HGNC Symbol;Acc:HGNC:8723] | 17842 | 0.000 | 0.2143 | No |
| 21 | LUM | lumican [Source:HGNC Symbol;Acc:HGNC:6724] | 18794 | 0.000 | 0.1887 | No |
| 22 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19466 | 0.000 | 0.1706 | No |
| 23 | COL3A1 | collagen type III alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2201] | 19651 | 0.000 | 0.1656 | No |
| 24 | PF4 | platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861] | 20014 | 0.000 | 0.1558 | No |
| 25 | COL5A2 | collagen type V alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2210] | 20385 | 0.000 | 0.1458 | No |
| 26 | PGLYRP1 | peptidoglycan recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:8904] | 20863 | 0.000 | 0.1330 | No |
| 27 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 21471 | 0.000 | 0.1166 | No |
| 28 | STC1 | stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373] | 27657 | 0.000 | -0.0503 | No |
| 29 | LRPAP1 | LDL receptor related protein associated protein 1 [Source:HGNC Symbol;Acc:HGNC:6701] | 28174 | -0.059 | -0.0614 | No |
| 30 | VCAN | versican [Source:HGNC Symbol;Acc:HGNC:2464] | 29361 | -0.226 | -0.0823 | No |
| 31 | APP | amyloid beta precursor protein [Source:HGNC Symbol;Acc:HGNC:620] | 30254 | -0.347 | -0.0893 | No |
| 32 | VEGFA | vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680] | 30658 | -0.411 | -0.0801 | No |
| 33 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 30805 | -0.432 | -0.0628 | No |
| 34 | JAG1 | jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188] | 32521 | -0.751 | -0.0723 | No |
| 35 | JAG2 | jagged canonical Notch ligand 2 [Source:HGNC Symbol;Acc:HGNC:6189] | 33795 | -1.111 | -0.0522 | No |
| 36 | NRP1 | neuropilin 1 [Source:HGNC Symbol;Acc:HGNC:8004] | 36599 | -2.879 | 0.0133 | No |
