Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | HALLMARK_MYC_TARGETS_V2 |
| Enrichment Score (ES) | 0.57078516 |
| Normalized Enrichment Score (NES) | 1.3235078 |
| Nominal p-value | 0.04411765 |
| FDR q-value | 0.06529663 |
| FWER p-Value | 0.147 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 16 | 4.622 | 0.0595 | Yes |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 18 | 4.578 | 0.1189 | Yes |
| 3 | GRWD1 | glutamate rich WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:21270] | 355 | 2.371 | 0.1406 | Yes |
| 4 | RRP12 | ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100] | 365 | 2.345 | 0.1708 | Yes |
| 5 | RRP9 | ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829] | 418 | 2.231 | 0.1983 | Yes |
| 6 | MYBBP1A | MYB binding protein 1a [Source:HGNC Symbol;Acc:HGNC:7546] | 488 | 2.103 | 0.2237 | Yes |
| 7 | NIP7 | nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328] | 533 | 2.024 | 0.2488 | Yes |
| 8 | NOP2 | NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867] | 585 | 1.940 | 0.2726 | Yes |
| 9 | UTP20 | UTP20 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897] | 796 | 1.668 | 0.2886 | Yes |
| 10 | NOP16 | NOP16 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:26934] | 917 | 1.543 | 0.3054 | Yes |
| 11 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 959 | 1.508 | 0.3238 | Yes |
| 12 | WDR43 | WD repeat domain 43 [Source:HGNC Symbol;Acc:HGNC:28945] | 1046 | 1.438 | 0.3402 | Yes |
| 13 | BYSL | bystin like [Source:HGNC Symbol;Acc:HGNC:1157] | 1058 | 1.432 | 0.3584 | Yes |
| 14 | TCOF1 | treacle ribosome biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:11654] | 1224 | 1.315 | 0.3710 | Yes |
| 15 | PPRC1 | PPARG related coactivator 1 [Source:HGNC Symbol;Acc:HGNC:30025] | 1228 | 1.311 | 0.3880 | Yes |
| 16 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 1435 | 1.187 | 0.3978 | Yes |
| 17 | DDX18 | DEAD-box helicase 18 [Source:HGNC Symbol;Acc:HGNC:2741] | 1518 | 1.147 | 0.4105 | Yes |
| 18 | MRTO4 | MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477] | 1556 | 1.133 | 0.4242 | Yes |
| 19 | IMP4 | IMP U3 small nucleolar ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:30856] | 1580 | 1.127 | 0.4382 | Yes |
| 20 | HK2 | hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923] | 1737 | 1.045 | 0.4475 | Yes |
| 21 | PHB | prohibitin [Source:HGNC Symbol;Acc:HGNC:8912] | 1761 | 1.032 | 0.4603 | Yes |
| 22 | PUS1 | pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:15508] | 1766 | 1.029 | 0.4735 | Yes |
| 23 | FARSA | phenylalanyl-tRNA synthetase subunit alpha [Source:HGNC Symbol;Acc:HGNC:3592] | 1790 | 1.020 | 0.4861 | Yes |
| 24 | NOP56 | NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911] | 1806 | 1.013 | 0.4989 | Yes |
| 25 | GNL3 | G protein nucleolar 3 [Source:HGNC Symbol;Acc:HGNC:29931] | 1832 | 1.005 | 0.5113 | Yes |
| 26 | RCL1 | RNA terminal phosphate cyclase like 1 [Source:HGNC Symbol;Acc:HGNC:17687] | 1894 | 0.982 | 0.5223 | Yes |
| 27 | SRM | spermidine synthase [Source:HGNC Symbol;Acc:HGNC:11296] | 2113 | 0.891 | 0.5280 | Yes |
| 28 | NOLC1 | nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15608] | 2285 | 0.832 | 0.5342 | Yes |
| 29 | NOC4L | nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461] | 2318 | 0.821 | 0.5440 | Yes |
| 30 | HSPD1 | heat shock protein family D (Hsp60) member 1 [Source:HGNC Symbol;Acc:HGNC:5261] | 2325 | 0.818 | 0.5544 | Yes |
| 31 | WDR74 | WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529] | 2704 | 0.704 | 0.5534 | Yes |
| 32 | SLC19A1 | solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937] | 2820 | 0.678 | 0.5591 | Yes |
| 33 | PES1 | pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8848] | 2963 | 0.639 | 0.5635 | Yes |
| 34 | MPHOSPH10 | M-phase phosphoprotein 10 [Source:HGNC Symbol;Acc:HGNC:7213] | 3035 | 0.623 | 0.5697 | Yes |
| 35 | AIMP2 | aminoacyl tRNA synthetase complex interacting multifunctional protein 2 [Source:HGNC Symbol;Acc:HGNC:20609] | 3353 | 0.551 | 0.5683 | Yes |
| 36 | LAS1L | LAS1 like ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:25726] | 3515 | 0.509 | 0.5705 | Yes |
| 37 | NDUFAF4 | NADH:ubiquinone oxidoreductase complex assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:21034] | 3730 | 0.466 | 0.5708 | Yes |
| 38 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 4412 | 0.341 | 0.5568 | No |
| 39 | HSPE1 | heat shock protein family E (Hsp10) member 1 [Source:HGNC Symbol;Acc:HGNC:5269] | 4450 | 0.335 | 0.5602 | No |
| 40 | NPM1 | nucleophosmin 1 [Source:HGNC Symbol;Acc:HGNC:7910] | 5103 | 0.222 | 0.5455 | No |
| 41 | TBRG4 | transforming growth factor beta regulator 4 [Source:HGNC Symbol;Acc:HGNC:17443] | 6140 | 0.072 | 0.5184 | No |
| 42 | PPAN | peter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227] | 28743 | -0.137 | -0.0901 | No |
| 43 | RABEPK | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] | 29089 | -0.184 | -0.0971 | No |
| 44 | PRMT3 | protein arginine methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30163] | 29830 | -0.293 | -0.1132 | No |
| 45 | SUPV3L1 | Suv3 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:11471] | 29831 | -0.293 | -0.1094 | No |
| 46 | TFB2M | transcription factor B2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:18559] | 30096 | -0.329 | -0.1123 | No |
| 47 | TMEM97 | transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106] | 30781 | -0.429 | -0.1252 | No |
| 48 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 33697 | -1.078 | -0.1899 | No |
| 49 | SLC29A2 | solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004] | 33833 | -1.124 | -0.1790 | No |
| 50 | CDK4 | cyclin dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773] | 34451 | -1.336 | -0.1783 | No |
| 51 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34655 | -1.411 | -0.1655 | No |
| 52 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 34860 | -1.492 | -0.1516 | No |
| 53 | EXOSC5 | exosome component 5 [Source:HGNC Symbol;Acc:HGNC:24662] | 35582 | -1.889 | -0.1466 | No |
| 54 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 35755 | -2.023 | -0.1250 | No |
| 55 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 36350 | -2.527 | -0.1082 | No |
| 56 | MAP3K6 | mitogen-activated protein kinase kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6858] | 36427 | -2.617 | -0.0763 | No |
| 57 | SORD | sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184] | 36581 | -2.858 | -0.0434 | No |
| 58 | UNG | uracil DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:12572] | 37063 | -4.399 | 0.0007 | No |
