Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | HALLMARK_PEROXISOME |
| Enrichment Score (ES) | -0.59398675 |
| Normalized Enrichment Score (NES) | -1.2641842 |
| Nominal p-value | 0.078179695 |
| FDR q-value | 0.18078944 |
| FWER p-Value | 0.9 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 223 | 2.834 | 0.0198 | No |
| 2 | ATXN1 | ataxin 1 [Source:HGNC Symbol;Acc:HGNC:10548] | 244 | 2.754 | 0.0444 | No |
| 3 | ACSL4 | acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] | 375 | 2.305 | 0.0619 | No |
| 4 | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:3433] | 570 | 1.964 | 0.0746 | No |
| 5 | SLC25A19 | solute carrier family 25 member 19 [Source:HGNC Symbol;Acc:HGNC:14409] | 797 | 1.667 | 0.0837 | No |
| 6 | PRDX5 | peroxiredoxin 5 [Source:HGNC Symbol;Acc:HGNC:9355] | 834 | 1.624 | 0.0975 | No |
| 7 | CNBP | CCHC-type zinc finger nucleic acid binding protein [Source:HGNC Symbol;Acc:HGNC:13164] | 1102 | 1.393 | 0.1030 | No |
| 8 | ACOX1 | acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119] | 1199 | 1.330 | 0.1126 | No |
| 9 | PEX11A | peroxisomal biogenesis factor 11 alpha [Source:HGNC Symbol;Acc:HGNC:8852] | 1408 | 1.199 | 0.1179 | No |
| 10 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1490 | 1.159 | 0.1263 | No |
| 11 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 1602 | 1.113 | 0.1334 | No |
| 12 | TSPO | translocator protein [Source:HGNC Symbol;Acc:HGNC:1158] | 1809 | 1.013 | 0.1371 | No |
| 13 | CDK7 | cyclin dependent kinase 7 [Source:HGNC Symbol;Acc:HGNC:1778] | 1936 | 0.963 | 0.1425 | No |
| 14 | DHRS3 | dehydrogenase/reductase 3 [Source:HGNC Symbol;Acc:HGNC:17693] | 2650 | 0.717 | 0.1297 | No |
| 15 | BCL10 | BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989] | 3152 | 0.595 | 0.1216 | No |
| 16 | IDI1 | isopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5387] | 3265 | 0.568 | 0.1238 | No |
| 17 | VPS4B | vacuolar protein sorting 4 homolog B [Source:HGNC Symbol;Acc:HGNC:10895] | 3340 | 0.553 | 0.1268 | No |
| 18 | YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta [Source:HGNC Symbol;Acc:HGNC:12853] | 3491 | 0.516 | 0.1275 | No |
| 19 | CRABP2 | cellular retinoic acid binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2339] | 3723 | 0.467 | 0.1255 | No |
| 20 | ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3435] | 3852 | 0.444 | 0.1261 | No |
| 21 | HRAS | HRas proto-oncogene, GTPase [Source:HGNC Symbol;Acc:HGNC:5173] | 4623 | 0.309 | 0.1081 | No |
| 22 | PEX5 | peroxisomal biogenesis factor 5 [Source:HGNC Symbol;Acc:HGNC:9719] | 4982 | 0.247 | 0.1006 | No |
| 23 | CACNA1B | calcium voltage-gated channel subunit alpha1 B [Source:HGNC Symbol;Acc:HGNC:1389] | 5286 | 0.195 | 0.0942 | No |
| 24 | SEMA3C | semaphorin 3C [Source:HGNC Symbol;Acc:HGNC:10725] | 5772 | 0.127 | 0.0823 | No |
| 25 | ITGB1BP1 | integrin subunit beta 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23927] | 5790 | 0.125 | 0.0829 | No |
| 26 | PABPC1 | poly(A) binding protein cytoplasmic 1 [Source:HGNC Symbol;Acc:HGNC:8554] | 6154 | 0.069 | 0.0738 | No |
| 27 | ABCB9 | ATP binding cassette subfamily B member 9 [Source:HGNC Symbol;Acc:HGNC:50] | 6166 | 0.067 | 0.0741 | No |
| 28 | FIS1 | fission, mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:21689] | 6285 | 0.044 | 0.0713 | No |
| 29 | PEX13 | peroxisomal biogenesis factor 13 [Source:HGNC Symbol;Acc:HGNC:8855] | 6293 | 0.043 | 0.0715 | No |
| 30 | EPHX2 | epoxide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3402] | 8153 | 0.000 | 0.0212 | No |
| 31 | EHHADH | enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247] | 8168 | 0.000 | 0.0209 | No |
| 32 | GSTK1 | glutathione S-transferase kappa 1 [Source:HGNC Symbol;Acc:HGNC:16906] | 9831 | 0.000 | -0.0241 | No |
| 33 | SLC27A2 | solute carrier family 27 member 2 [Source:HGNC Symbol;Acc:HGNC:10996] | 11078 | 0.000 | -0.0578 | No |
| 34 | ESR2 | estrogen receptor 2 [Source:HGNC Symbol;Acc:HGNC:3468] | 12105 | 0.000 | -0.0855 | No |
| 35 | STS | steroid sulfatase [Source:HGNC Symbol;Acc:HGNC:11425] | 12577 | 0.000 | -0.0982 | No |
| 36 | TTR | transthyretin [Source:HGNC Symbol;Acc:HGNC:12405] | 12838 | 0.000 | -0.1053 | No |
| 37 | HSD11B2 | hydroxysteroid 11-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5209] | 14538 | 0.000 | -0.1512 | No |
| 38 | CEL | carboxyl ester lipase [Source:HGNC Symbol;Acc:HGNC:1848] | 15845 | 0.000 | -0.1865 | No |
| 39 | DIO1 | iodothyronine deiodinase 1 [Source:HGNC Symbol;Acc:HGNC:2883] | 15904 | 0.000 | -0.1881 | No |
| 40 | SERPINA6 | serpin family A member 6 [Source:HGNC Symbol;Acc:HGNC:1540] | 17839 | 0.000 | -0.2404 | No |
| 41 | UGT2B17 | UDP glucuronosyltransferase family 2 member B17 [Source:HGNC Symbol;Acc:HGNC:12547] | 18223 | 0.000 | -0.2507 | No |
| 42 | NR1I2 | nuclear receptor subfamily 1 group I member 2 [Source:HGNC Symbol;Acc:HGNC:7968] | 19977 | 0.000 | -0.2981 | No |
| 43 | SULT2B1 | sulfotransferase family 2B member 1 [Source:HGNC Symbol;Acc:HGNC:11459] | 23955 | 0.000 | -0.4057 | No |
| 44 | CRABP1 | cellular retinoic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2338] | 24233 | 0.000 | -0.4131 | No |
| 45 | SCGB1A1 | secretoglobin family 1A member 1 [Source:HGNC Symbol;Acc:HGNC:12523] | 24425 | 0.000 | -0.4183 | No |
| 46 | HAO2 | hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810] | 25097 | 0.000 | -0.4364 | No |
| 47 | ALDH1A1 | aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] | 25945 | 0.000 | -0.4593 | No |
| 48 | FABP6 | fatty acid binding protein 6 [Source:HGNC Symbol;Acc:HGNC:3561] | 27135 | 0.000 | -0.4915 | No |
| 49 | ALB | albumin [Source:HGNC Symbol;Acc:HGNC:399] | 27537 | 0.000 | -0.5023 | No |
| 50 | CTBP1 | C-terminal binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2494] | 28631 | -0.122 | -0.5308 | No |
| 51 | RDH11 | retinol dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:17964] | 29229 | -0.204 | -0.5451 | No |
| 52 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 29328 | -0.220 | -0.5457 | No |
| 53 | PEX2 | peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717] | 29683 | -0.269 | -0.5528 | No |
| 54 | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 [Source:HGNC Symbol;Acc:HGNC:11104] | 29795 | -0.289 | -0.5532 | No |
| 55 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 29798 | -0.290 | -0.5506 | No |
| 56 | ABCC8 | ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59] | 30086 | -0.328 | -0.5554 | No |
| 57 | SLC23A2 | solute carrier family 23 member 2 [Source:HGNC Symbol;Acc:HGNC:10973] | 30539 | -0.390 | -0.5640 | No |
| 58 | SIAH1 | siah E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:10857] | 30545 | -0.391 | -0.5606 | No |
| 59 | PEX14 | peroxisomal biogenesis factor 14 [Source:HGNC Symbol;Acc:HGNC:8856] | 30573 | -0.396 | -0.5577 | No |
| 60 | GNPAT | glyceronephosphate O-acyltransferase [Source:HGNC Symbol;Acc:HGNC:4416] | 30629 | -0.407 | -0.5555 | No |
| 61 | IDE | insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381] | 31048 | -0.469 | -0.5625 | No |
| 62 | PEX6 | peroxisomal biogenesis factor 6 [Source:HGNC Symbol;Acc:HGNC:8859] | 31117 | -0.479 | -0.5600 | No |
| 63 | NUDT19 | nudix hydrolase 19 [Source:HGNC Symbol;Acc:HGNC:32036] | 31166 | -0.488 | -0.5568 | No |
| 64 | CTPS1 | CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] | 31341 | -0.517 | -0.5568 | No |
| 65 | ACSL5 | acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526] | 31518 | -0.549 | -0.5565 | No |
| 66 | ISOC1 | isochorismatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24254] | 31779 | -0.594 | -0.5582 | No |
| 67 | ACOT8 | acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919] | 32328 | -0.708 | -0.5665 | No |
| 68 | CLN8 | CLN8 transmembrane ER and ERGIC protein [Source:HGNC Symbol;Acc:HGNC:2079] | 33345 | -0.971 | -0.5851 | Yes |
| 69 | SLC25A17 | solute carrier family 25 member 17 [Source:HGNC Symbol;Acc:HGNC:10987] | 33398 | -0.986 | -0.5775 | Yes |
| 70 | ACSL1 | acyl-CoA synthetase long chain family member 1 [Source:HGNC Symbol;Acc:HGNC:3569] | 33710 | -1.081 | -0.5761 | Yes |
| 71 | HMGCL | 3-hydroxy-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:5005] | 33935 | -1.162 | -0.5715 | Yes |
| 72 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 34027 | -1.192 | -0.5631 | Yes |
| 73 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 34050 | -1.199 | -0.5528 | Yes |
| 74 | FDPS | farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631] | 34131 | -1.218 | -0.5438 | Yes |
| 75 | DLG4 | discs large MAGUK scaffold protein 4 [Source:HGNC Symbol;Acc:HGNC:2903] | 34183 | -1.239 | -0.5339 | Yes |
| 76 | SLC25A4 | solute carrier family 25 member 4 [Source:HGNC Symbol;Acc:HGNC:10990] | 34208 | -1.248 | -0.5232 | Yes |
| 77 | HSD3B7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [Source:HGNC Symbol;Acc:HGNC:18324] | 34477 | -1.343 | -0.5182 | Yes |
| 78 | LONP2 | lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598] | 34590 | -1.388 | -0.5085 | Yes |
| 79 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 34936 | -1.532 | -0.5039 | Yes |
| 80 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 34998 | -1.564 | -0.4913 | Yes |
| 81 | RETSAT | retinol saturase [Source:HGNC Symbol;Acc:HGNC:25991] | 35100 | -1.626 | -0.4792 | Yes |
| 82 | SCP2 | sterol carrier protein 2 [Source:HGNC Symbol;Acc:HGNC:10606] | 35297 | -1.729 | -0.4687 | Yes |
| 83 | RXRG | retinoid X receptor gamma [Source:HGNC Symbol;Acc:HGNC:10479] | 35365 | -1.760 | -0.4545 | Yes |
| 84 | ABCD3 | ATP binding cassette subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:67] | 35419 | -1.787 | -0.4396 | Yes |
| 85 | HSD17B4 | hydroxysteroid 17-beta dehydrogenase 4 [Source:HGNC Symbol;Acc:HGNC:5213] | 35498 | -1.835 | -0.4250 | Yes |
| 86 | DHCR24 | 24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859] | 35555 | -1.870 | -0.4094 | Yes |
| 87 | CADM1 | cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5951] | 35717 | -1.991 | -0.3956 | Yes |
| 88 | ECI2 | enoyl-CoA delta isomerase 2 [Source:HGNC Symbol;Acc:HGNC:14601] | 35952 | -2.174 | -0.3821 | Yes |
| 89 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35959 | -2.181 | -0.3624 | Yes |
| 90 | IDH2 | isocitrate dehydrogenase (NADP(+)) 2 [Source:HGNC Symbol;Acc:HGNC:5383] | 35984 | -2.196 | -0.3430 | Yes |
| 91 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 36196 | -2.360 | -0.3272 | Yes |
| 92 | ABCB4 | ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] | 36200 | -2.364 | -0.3057 | Yes |
| 93 | ACAA1 | acetyl-CoA acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:82] | 36210 | -2.370 | -0.2843 | Yes |
| 94 | ELOVL5 | ELOVL fatty acid elongase 5 [Source:HGNC Symbol;Acc:HGNC:21308] | 36230 | -2.394 | -0.2630 | Yes |
| 95 | CRAT | carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342] | 36234 | -2.397 | -0.2412 | Yes |
| 96 | ABCC5 | ATP binding cassette subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:56] | 36260 | -2.426 | -0.2197 | Yes |
| 97 | FADS1 | fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] | 36282 | -2.449 | -0.1980 | Yes |
| 98 | ABCD1 | ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61] | 36461 | -2.663 | -0.1785 | Yes |
| 99 | ALDH9A1 | aldehyde dehydrogenase 9 family member A1 [Source:HGNC Symbol;Acc:HGNC:412] | 36561 | -2.810 | -0.1555 | Yes |
| 100 | ECH1 | enoyl-CoA hydratase 1 [Source:HGNC Symbol;Acc:HGNC:3149] | 36642 | -2.940 | -0.1309 | Yes |
| 101 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36736 | -3.113 | -0.1050 | Yes |
| 102 | IDH1 | isocitrate dehydrogenase (NADP(+)) 1 [Source:HGNC Symbol;Acc:HGNC:5382] | 36914 | -3.618 | -0.0768 | Yes |
| 103 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 37024 | -4.108 | -0.0423 | Yes |
| 104 | ABCD2 | ATP binding cassette subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:66] | 37084 | -4.825 | 0.0002 | Yes |
