Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_GAQ |
| GeneSet | HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY |
| Enrichment Score (ES) | 0.46187255 |
| Normalized Enrichment Score (NES) | 1.0284623 |
| Nominal p-value | 0.33632287 |
| FDR q-value | 0.41621554 |
| FWER p-Value | 0.869 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 116 | 3.363 | 0.0590 | Yes |
| 2 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 126 | 3.278 | 0.1193 | Yes |
| 3 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 148 | 3.174 | 0.1773 | Yes |
| 4 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 223 | 2.834 | 0.2277 | Yes |
| 5 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 236 | 2.780 | 0.2787 | Yes |
| 6 | SRXN1 | sulfiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:16132] | 419 | 2.230 | 0.3150 | Yes |
| 7 | SELENOS | selenoprotein S [Source:HGNC Symbol;Acc:HGNC:30396] | 673 | 1.827 | 0.3419 | Yes |
| 8 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 773 | 1.699 | 0.3706 | Yes |
| 9 | ABCC1 | ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51] | 1016 | 1.462 | 0.3911 | Yes |
| 10 | EGLN2 | egl-9 family hypoxia inducible factor 2 [Source:HGNC Symbol;Acc:HGNC:14660] | 1425 | 1.192 | 0.4021 | Yes |
| 11 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 1490 | 1.159 | 0.4218 | Yes |
| 12 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1742 | 1.042 | 0.4343 | Yes |
| 13 | SCAF4 | SR-related CTD associated factor 4 [Source:HGNC Symbol;Acc:HGNC:19304] | 2234 | 0.850 | 0.4367 | Yes |
| 14 | GSR | glutathione-disulfide reductase [Source:HGNC Symbol;Acc:HGNC:4623] | 2380 | 0.796 | 0.4475 | Yes |
| 15 | MSRA | methionine sulfoxide reductase A [Source:HGNC Symbol;Acc:HGNC:7377] | 2734 | 0.698 | 0.4508 | Yes |
| 16 | G6PD | glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] | 2920 | 0.650 | 0.4579 | Yes |
| 17 | LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Source:HGNC Symbol;Acc:HGNC:17955] | 3175 | 0.589 | 0.4619 | Yes |
| 18 | HHEX | hematopoietically expressed homeobox [Source:HGNC Symbol;Acc:HGNC:4901] | 4066 | 0.405 | 0.4453 | No |
| 19 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3434] | 4166 | 0.389 | 0.4498 | No |
| 20 | NQO1 | NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874] | 4725 | 0.292 | 0.4402 | No |
| 21 | GLRX2 | glutaredoxin 2 [Source:HGNC Symbol;Acc:HGNC:16065] | 4743 | 0.289 | 0.4451 | No |
| 22 | ATOX1 | antioxidant 1 copper chaperone [Source:HGNC Symbol;Acc:HGNC:798] | 6156 | 0.069 | 0.4082 | No |
| 23 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9664 | 0.000 | 0.3135 | No |
| 24 | MGST1 | microsomal glutathione S-transferase 1 [Source:HGNC Symbol;Acc:HGNC:7061] | 12005 | 0.000 | 0.2504 | No |
| 25 | IPCEF1 | interaction protein for cytohesin exchange factors 1 [Source:HGNC Symbol;Acc:HGNC:21204] | 17971 | 0.000 | 0.0893 | No |
| 26 | MPO | myeloperoxidase [Source:HGNC Symbol;Acc:HGNC:7218] | 19051 | 0.000 | 0.0602 | No |
| 27 | NDUFB4 | NADH:ubiquinone oxidoreductase subunit B4 [Source:HGNC Symbol;Acc:HGNC:7699] | 23049 | 0.000 | -0.0477 | No |
| 28 | PRDX2 | peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353] | 28101 | -0.047 | -0.1832 | No |
| 29 | STK25 | serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404] | 28960 | -0.165 | -0.2033 | No |
| 30 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 29328 | -0.220 | -0.2091 | No |
| 31 | FTL | ferritin light chain [Source:HGNC Symbol;Acc:HGNC:3999] | 29464 | -0.239 | -0.2084 | No |
| 32 | PDLIM1 | PDZ and LIM domain 1 [Source:HGNC Symbol;Acc:HGNC:2067] | 30129 | -0.333 | -0.2201 | No |
| 33 | TXNRD2 | thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155] | 30624 | -0.406 | -0.2260 | No |
| 34 | OXSR1 | oxidative stress responsive kinase 1 [Source:HGNC Symbol;Acc:HGNC:8508] | 31109 | -0.479 | -0.2302 | No |
| 35 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 31269 | -0.505 | -0.2252 | No |
| 36 | PTPA | protein phosphatase 2 phosphatase activator [Source:HGNC Symbol;Acc:HGNC:9308] | 32231 | -0.689 | -0.2384 | No |
| 37 | HMOX2 | heme oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:5014] | 32246 | -0.692 | -0.2260 | No |
| 38 | FES | FES proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3657] | 32493 | -0.744 | -0.2189 | No |
| 39 | GCLC | glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311] | 32947 | -0.861 | -0.2152 | No |
| 40 | NDUFA6 | NADH:ubiquinone oxidoreductase subunit A6 [Source:HGNC Symbol;Acc:HGNC:7690] | 33548 | -1.035 | -0.2123 | No |
| 41 | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2 [Source:HGNC Symbol;Acc:HGNC:7708] | 33603 | -1.050 | -0.1944 | No |
| 42 | LSP1 | lymphocyte specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707] | 34009 | -1.188 | -0.1834 | No |
| 43 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 34050 | -1.199 | -0.1623 | No |
| 44 | PRDX6 | peroxiredoxin 6 [Source:HGNC Symbol;Acc:HGNC:16753] | 34349 | -1.299 | -0.1463 | No |
| 45 | PRNP | prion protein [Source:HGNC Symbol;Acc:HGNC:9449] | 35495 | -1.834 | -0.1434 | No |
| 46 | PFKP | phosphofructokinase, platelet [Source:HGNC Symbol;Acc:HGNC:8878] | 35663 | -1.948 | -0.1119 | No |
| 47 | MBP | myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925] | 36104 | -2.280 | -0.0817 | No |
| 48 | CDKN2D | cyclin dependent kinase inhibitor 2D [Source:HGNC Symbol;Acc:HGNC:1790] | 36520 | -2.755 | -0.0420 | No |
| 49 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 36733 | -3.106 | 0.0096 | No |
