Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_GAQ_versus_KO_NA.Nof1.cls #KO_GAQ_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_GAQ_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | HALLMARK_SPERMATOGENESIS |
| Enrichment Score (ES) | -0.58841175 |
| Normalized Enrichment Score (NES) | -1.2759061 |
| Nominal p-value | 0.040929202 |
| FDR q-value | 0.2091688 |
| FWER p-Value | 0.867 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 169 | 3.064 | 0.0343 | No |
| 2 | PGS1 | phosphatidylglycerophosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:30029] | 1161 | 1.351 | 0.0246 | No |
| 3 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 1315 | 1.264 | 0.0365 | No |
| 4 | TLE4 | TLE family member 4, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11840] | 1334 | 1.253 | 0.0519 | No |
| 5 | DPEP3 | dipeptidase 3 [Source:HGNC Symbol;Acc:HGNC:23029] | 1505 | 1.153 | 0.0620 | No |
| 6 | STAM2 | signal transducing adaptor molecule 2 [Source:HGNC Symbol;Acc:HGNC:11358] | 1713 | 1.055 | 0.0697 | No |
| 7 | ELOVL3 | ELOVL fatty acid elongase 3 [Source:HGNC Symbol;Acc:HGNC:18047] | 1870 | 0.990 | 0.0781 | No |
| 8 | ARL4A | ADP ribosylation factor like GTPase 4A [Source:HGNC Symbol;Acc:HGNC:695] | 1938 | 0.963 | 0.0885 | No |
| 9 | TSN | translin [Source:HGNC Symbol;Acc:HGNC:12379] | 3451 | 0.524 | 0.0542 | No |
| 10 | RAD17 | RAD17 checkpoint clamp loader component [Source:HGNC Symbol;Acc:HGNC:9807] | 3502 | 0.512 | 0.0594 | No |
| 11 | PAPOLB | poly(A) polymerase beta [Source:HGNC Symbol;Acc:HGNC:15970] | 3532 | 0.506 | 0.0650 | No |
| 12 | SNAP91 | synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986] | 3706 | 0.470 | 0.0663 | No |
| 13 | AGFG1 | ArfGAP with FG repeats 1 [Source:HGNC Symbol;Acc:HGNC:5175] | 3876 | 0.439 | 0.0673 | No |
| 14 | NAA11 | N-alpha-acetyltransferase 11, NatA catalytic subunit [Source:HGNC Symbol;Acc:HGNC:28125] | 3890 | 0.438 | 0.0725 | No |
| 15 | PIAS2 | protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311] | 3967 | 0.422 | 0.0758 | No |
| 16 | LDHC | lactate dehydrogenase C [Source:HGNC Symbol;Acc:HGNC:6544] | 4110 | 0.398 | 0.0770 | No |
| 17 | RPL39L | ribosomal protein L39 like [Source:HGNC Symbol;Acc:HGNC:17094] | 4406 | 0.342 | 0.0733 | No |
| 18 | TEKT2 | tektin 2 [Source:HGNC Symbol;Acc:HGNC:11725] | 4480 | 0.331 | 0.0756 | No |
| 19 | PHF7 | PHD finger protein 7 [Source:HGNC Symbol;Acc:HGNC:18458] | 4849 | 0.269 | 0.0690 | No |
| 20 | MAST2 | microtubule associated serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:19035] | 5126 | 0.218 | 0.0643 | No |
| 21 | CSNK2A2 | casein kinase 2 alpha 2 [Source:HGNC Symbol;Acc:HGNC:2459] | 5382 | 0.178 | 0.0597 | No |
| 22 | ACTL7B | actin like 7B [Source:HGNC Symbol;Acc:HGNC:162] | 5759 | 0.129 | 0.0511 | No |
| 23 | MLLT10 | MLLT10 histone lysine methyltransferase DOT1L cofactor [Source:HGNC Symbol;Acc:HGNC:16063] | 6222 | 0.056 | 0.0393 | No |
| 24 | COIL | coilin [Source:HGNC Symbol;Acc:HGNC:2184] | 6224 | 0.056 | 0.0400 | No |
| 25 | SHE | Src homology 2 domain containing E [Source:HGNC Symbol;Acc:HGNC:27004] | 6243 | 0.052 | 0.0402 | No |
| 26 | TALDO1 | transaldolase 1 [Source:HGNC Symbol;Acc:HGNC:11559] | 6345 | 0.033 | 0.0379 | No |
| 27 | PHKG2 | phosphorylase kinase catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:8931] | 6373 | 0.026 | 0.0375 | No |
| 28 | SCG5 | secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816] | 6775 | 0.000 | 0.0266 | No |
| 29 | SCG3 | secretogranin III [Source:HGNC Symbol;Acc:HGNC:13707] | 6777 | 0.000 | 0.0266 | No |
| 30 | ADCYAP1 | adenylate cyclase activating polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:241] | 7570 | 0.000 | 0.0052 | No |
| 31 | ART3 | ADP-ribosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:725] | 7678 | 0.000 | 0.0023 | No |
| 32 | CCNA1 | cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577] | 7782 | 0.000 | -0.0005 | No |
| 33 | ZC2HC1C | zinc finger C2HC-type containing 1C [Source:HGNC Symbol;Acc:HGNC:20354] | 8476 | 0.000 | -0.0193 | No |
| 34 | HOXB1 | homeobox B1 [Source:HGNC Symbol;Acc:HGNC:5111] | 9020 | 0.000 | -0.0339 | No |
| 35 | ADAM2 | ADAM metallopeptidase domain 2 [Source:HGNC Symbol;Acc:HGNC:198] | 9100 | 0.000 | -0.0361 | No |
| 36 | ADAD1 | adenosine deaminase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30713] | 9249 | 0.000 | -0.0401 | No |
| 37 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 9270 | 0.000 | -0.0406 | No |
| 38 | CRISP2 | cysteine rich secretory protein 2 [Source:HGNC Symbol;Acc:HGNC:12024] | 9310 | 0.000 | -0.0417 | No |
| 39 | NPY5R | neuropeptide Y receptor Y5 [Source:HGNC Symbol;Acc:HGNC:7958] | 9317 | 0.000 | -0.0418 | No |
| 40 | DMRT1 | doublesex and mab-3 related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:2934] | 9751 | 0.000 | -0.0536 | No |
| 41 | GSTM3 | glutathione S-transferase mu 3 [Source:HGNC Symbol;Acc:HGNC:4635] | 9844 | 0.000 | -0.0561 | No |
| 42 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 10142 | 0.000 | -0.0641 | No |
| 43 | TULP2 | TUB like protein 2 [Source:HGNC Symbol;Acc:HGNC:12424] | 10313 | 0.000 | -0.0687 | No |
| 44 | CFTR | CF transmembrane conductance regulator [Source:HGNC Symbol;Acc:HGNC:1884] | 10346 | 0.000 | -0.0696 | No |
| 45 | PRM2 | protamine 2 [Source:HGNC Symbol;Acc:HGNC:9448] | 11723 | 0.000 | -0.1068 | No |
| 46 | SEPTIN4 | septin 4 [Source:HGNC Symbol;Acc:HGNC:9165] | 11899 | 0.000 | -0.1115 | No |
| 47 | JAM3 | junctional adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:15532] | 12247 | 0.000 | -0.1209 | No |
| 48 | THEG | theg spermatid protein [Source:HGNC Symbol;Acc:HGNC:13706] | 12861 | 0.000 | -0.1375 | No |
| 49 | TCP11 | t-complex 11 [Source:HGNC Symbol;Acc:HGNC:11658] | 14593 | 0.000 | -0.1843 | No |
| 50 | TNP2 | transition protein 2 [Source:HGNC Symbol;Acc:HGNC:11952] | 15113 | 0.000 | -0.1984 | No |
| 51 | TNP1 | transition protein 1 [Source:HGNC Symbol;Acc:HGNC:11951] | 15115 | 0.000 | -0.1984 | No |
| 52 | HTR5A | 5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300] | 15701 | 0.000 | -0.2142 | No |
| 53 | CLVS1 | clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139] | 15825 | 0.000 | -0.2176 | No |
| 54 | MTNR1A | melatonin receptor 1A [Source:HGNC Symbol;Acc:HGNC:7463] | 15906 | 0.000 | -0.2197 | No |
| 55 | DCC | DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701] | 16091 | 0.000 | -0.2247 | No |
| 56 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 16452 | 0.000 | -0.2345 | No |
| 57 | GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [Source:HGNC Symbol;Acc:HGNC:24864] | 16552 | 0.000 | -0.2371 | No |
| 58 | AKAP4 | A-kinase anchoring protein 4 [Source:HGNC Symbol;Acc:HGNC:374] | 16701 | 0.000 | -0.2411 | No |
| 59 | DMC1 | DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927] | 16962 | 0.000 | -0.2482 | No |
| 60 | TKTL1 | transketolase like 1 [Source:HGNC Symbol;Acc:HGNC:11835] | 17283 | 0.000 | -0.2568 | No |
| 61 | HBZ | hemoglobin subunit zeta [Source:HGNC Symbol;Acc:HGNC:4835] | 17329 | 0.000 | -0.2581 | No |
| 62 | SYCP1 | synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487] | 17899 | 0.000 | -0.2734 | No |
| 63 | DNAJB8 | DnaJ heat shock protein family (Hsp40) member B8 [Source:HGNC Symbol;Acc:HGNC:23699] | 18548 | 0.000 | -0.2910 | No |
| 64 | IL12RB2 | interleukin 12 receptor subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:5972] | 19646 | 0.000 | -0.3207 | No |
| 65 | PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor [Source:HGNC Symbol;Acc:HGNC:17301] | 20797 | 0.000 | -0.3518 | No |
| 66 | H1-6 | H1.6 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4720] | 22910 | 0.000 | -0.4089 | No |
| 67 | DDX25 | DEAD-box helicase 25 [Source:HGNC Symbol;Acc:HGNC:18698] | 23270 | 0.000 | -0.4186 | No |
| 68 | MEP1B | meprin A subunit beta [Source:HGNC Symbol;Acc:HGNC:7020] | 23437 | 0.000 | -0.4231 | No |
| 69 | ACRV1 | acrosomal vesicle protein 1 [Source:HGNC Symbol;Acc:HGNC:127] | 23631 | 0.000 | -0.4284 | No |
| 70 | TSSK2 | testis specific serine kinase 2 [Source:HGNC Symbol;Acc:HGNC:11401] | 24765 | 0.000 | -0.4590 | No |
| 71 | CST8 | cystatin 8 [Source:HGNC Symbol;Acc:HGNC:2480] | 24927 | 0.000 | -0.4634 | No |
| 72 | ODF1 | outer dense fiber of sperm tails 1 [Source:HGNC Symbol;Acc:HGNC:8113] | 26681 | 0.000 | -0.5108 | No |
| 73 | ZNRF4 | zinc and ring finger 4 [Source:HGNC Symbol;Acc:HGNC:17726] | 26719 | 0.000 | -0.5118 | No |
| 74 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 27377 | 0.000 | -0.5296 | No |
| 75 | MAP7 | microtubule associated protein 7 [Source:HGNC Symbol;Acc:HGNC:6869] | 27665 | 0.000 | -0.5374 | No |
| 76 | SLC2A5 | solute carrier family 2 member 5 [Source:HGNC Symbol;Acc:HGNC:11010] | 27745 | 0.000 | -0.5395 | No |
| 77 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 27912 | -0.021 | -0.5437 | No |
| 78 | DDX4 | DEAD-box helicase 4 [Source:HGNC Symbol;Acc:HGNC:18700] | 28057 | -0.040 | -0.5471 | No |
| 79 | GFI1 | growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237] | 28114 | -0.049 | -0.5480 | No |
| 80 | PSMG1 | proteasome assembly chaperone 1 [Source:HGNC Symbol;Acc:HGNC:3043] | 28187 | -0.061 | -0.5492 | No |
| 81 | NEFH | neurofilament heavy [Source:HGNC Symbol;Acc:HGNC:7737] | 28319 | -0.079 | -0.5517 | No |
| 82 | CLGN | calmegin [Source:HGNC Symbol;Acc:HGNC:2060] | 28503 | -0.104 | -0.5554 | No |
| 83 | PEBP1 | phosphatidylethanolamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8630] | 28555 | -0.111 | -0.5553 | No |
| 84 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 28607 | -0.119 | -0.5552 | No |
| 85 | MTOR | mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942] | 28724 | -0.135 | -0.5566 | No |
| 86 | HSPA1L | heat shock protein family A (Hsp70) member 1 like [Source:HGNC Symbol;Acc:HGNC:5234] | 29155 | -0.193 | -0.5658 | No |
| 87 | TUBA3C | tubulin alpha 3c [Source:HGNC Symbol;Acc:HGNC:12408] | 29391 | -0.230 | -0.5693 | No |
| 88 | POMC | proopiomelanocortin [Source:HGNC Symbol;Acc:HGNC:9201] | 29623 | -0.261 | -0.5722 | No |
| 89 | BRAF | B-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1097] | 29744 | -0.281 | -0.5719 | No |
| 90 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 29951 | -0.310 | -0.5735 | No |
| 91 | VDAC3 | voltage dependent anion channel 3 [Source:HGNC Symbol;Acc:HGNC:12674] | 29985 | -0.314 | -0.5704 | No |
| 92 | GAD1 | glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092] | 30336 | -0.359 | -0.5753 | No |
| 93 | OAZ3 | ornithine decarboxylase antizyme 3 [Source:HGNC Symbol;Acc:HGNC:8097] | 30600 | -0.402 | -0.5774 | No |
| 94 | YBX2 | Y-box binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17948] | 30931 | -0.453 | -0.5805 | No |
| 95 | IDE | insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381] | 31048 | -0.469 | -0.5777 | No |
| 96 | MLF1 | myeloid leukemia factor 1 [Source:HGNC Symbol;Acc:HGNC:7125] | 31314 | -0.512 | -0.5784 | No |
| 97 | PRKAR2A | protein kinase cAMP-dependent type II regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9391] | 31685 | -0.575 | -0.5811 | Yes |
| 98 | IP6K1 | inositol hexakisphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:18360] | 31755 | -0.589 | -0.5755 | Yes |
| 99 | CLPB | caseinolytic mitochondrial matrix peptidase chaperone subunit B [Source:HGNC Symbol;Acc:HGNC:30664] | 31940 | -0.626 | -0.5726 | Yes |
| 100 | ZPBP | zona pellucida binding protein [Source:HGNC Symbol;Acc:HGNC:15662] | 32220 | -0.687 | -0.5714 | Yes |
| 101 | PACRG | parkin coregulated [Source:HGNC Symbol;Acc:HGNC:19152] | 32495 | -0.745 | -0.5694 | Yes |
| 102 | TNNI3 | troponin I3, cardiac type [Source:HGNC Symbol;Acc:HGNC:11947] | 32562 | -0.761 | -0.5615 | Yes |
| 103 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 32625 | -0.776 | -0.5533 | Yes |
| 104 | CHFR | checkpoint with forkhead and ring finger domains [Source:HGNC Symbol;Acc:HGNC:20455] | 32771 | -0.817 | -0.5469 | Yes |
| 105 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 32821 | -0.827 | -0.5377 | Yes |
| 106 | HSPA2 | heat shock protein family A (Hsp70) member 2 [Source:HGNC Symbol;Acc:HGNC:5235] | 33138 | -0.909 | -0.5347 | Yes |
| 107 | NOS1 | nitric oxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:7872] | 33201 | -0.929 | -0.5246 | Yes |
| 108 | PCSK4 | proprotein convertase subtilisin/kexin type 4 [Source:HGNC Symbol;Acc:HGNC:8746] | 33242 | -0.944 | -0.5137 | Yes |
| 109 | PARP2 | poly(ADP-ribose) polymerase 2 [Source:HGNC Symbol;Acc:HGNC:272] | 33340 | -0.969 | -0.5041 | Yes |
| 110 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 33366 | -0.976 | -0.4924 | Yes |
| 111 | SIRT1 | sirtuin 1 [Source:HGNC Symbol;Acc:HGNC:14929] | 33387 | -0.982 | -0.4804 | Yes |
| 112 | PDHA2 | pyruvate dehydrogenase E1 subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8807] | 33491 | -1.016 | -0.4703 | Yes |
| 113 | PGK2 | phosphoglycerate kinase 2 [Source:HGNC Symbol;Acc:HGNC:8898] | 33669 | -1.071 | -0.4615 | Yes |
| 114 | ACRBP | acrosin binding protein [Source:HGNC Symbol;Acc:HGNC:17195] | 34192 | -1.242 | -0.4599 | Yes |
| 115 | ZC3H14 | zinc finger CCCH-type containing 14 [Source:HGNC Symbol;Acc:HGNC:20509] | 34373 | -1.308 | -0.4482 | Yes |
| 116 | LPIN1 | lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345] | 34455 | -1.336 | -0.4334 | Yes |
| 117 | GSG1 | germ cell associated 1 [Source:HGNC Symbol;Acc:HGNC:19716] | 34536 | -1.365 | -0.4183 | Yes |
| 118 | NF2 | neurofibromin 2 [Source:HGNC Symbol;Acc:HGNC:7773] | 34561 | -1.375 | -0.4015 | Yes |
| 119 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 34826 | -1.475 | -0.3899 | Yes |
| 120 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 34997 | -1.563 | -0.3747 | Yes |
| 121 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35659 | -1.943 | -0.3679 | Yes |
| 122 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35732 | -2.004 | -0.3444 | Yes |
| 123 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 35886 | -2.120 | -0.3217 | Yes |
| 124 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35968 | -2.186 | -0.2961 | Yes |
| 125 | NPHP1 | nephrocystin 1 [Source:HGNC Symbol;Acc:HGNC:7905] | 35979 | -2.195 | -0.2686 | Yes |
| 126 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 36015 | -2.212 | -0.2415 | Yes |
| 127 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36062 | -2.250 | -0.2142 | Yes |
| 128 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36081 | -2.263 | -0.1859 | Yes |
| 129 | IFT88 | intraflagellar transport 88 [Source:HGNC Symbol;Acc:HGNC:20606] | 36089 | -2.269 | -0.1573 | Yes |
| 130 | TOPBP1 | DNA topoisomerase II binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17008] | 36130 | -2.301 | -0.1292 | Yes |
| 131 | GMCL1 | germ cell-less 1, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:23843] | 36183 | -2.351 | -0.1008 | Yes |
| 132 | HSPA4L | heat shock protein family A (Hsp70) member 4 like [Source:HGNC Symbol;Acc:HGNC:17041] | 36208 | -2.369 | -0.0714 | Yes |
| 133 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36249 | -2.411 | -0.0419 | Yes |
| 134 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36304 | -2.474 | -0.0120 | Yes |
| 135 | STRBP | spermatid perinuclear RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16462] | 36434 | -2.620 | 0.0178 | Yes |
