Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | CHR17Q12 |
| Enrichment Score (ES) | 0.47178012 |
| Normalized Enrichment Score (NES) | 1.2251017 |
| Nominal p-value | 0.01369863 |
| FDR q-value | 0.38522607 |
| FWER p-Value | 0.94 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 26 | 4.768 | 0.0497 | Yes |
| 2 | SLFN5 | schlafen family member 5 [Source:HGNC Symbol;Acc:HGNC:28286] | 65 | 4.376 | 0.0949 | Yes |
| 3 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 83 | 4.184 | 0.1387 | Yes |
| 4 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 127 | 3.902 | 0.1788 | Yes |
| 5 | SLFN13 | schlafen family member 13 [Source:HGNC Symbol;Acc:HGNC:26481] | 139 | 3.833 | 0.2190 | Yes |
| 6 | SLFN11 | schlafen family member 11 [Source:HGNC Symbol;Acc:HGNC:26633] | 170 | 3.623 | 0.2565 | Yes |
| 7 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 272 | 3.068 | 0.2862 | Yes |
| 8 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 589 | 2.154 | 0.3004 | Yes |
| 9 | RFFL | ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821] | 635 | 2.084 | 0.3212 | Yes |
| 10 | STARD3 | StAR related lipid transfer domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17579] | 775 | 1.858 | 0.3371 | Yes |
| 11 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 850 | 1.758 | 0.3536 | Yes |
| 12 | CDK12 | cyclin dependent kinase 12 [Source:HGNC Symbol;Acc:HGNC:24224] | 1261 | 1.341 | 0.3567 | Yes |
| 13 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 1262 | 1.339 | 0.3709 | Yes |
| 14 | CWC25 | CWC25 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:25989] | 1277 | 1.326 | 0.3845 | Yes |
| 15 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 1280 | 1.324 | 0.3984 | Yes |
| 16 | MIEN1 | migration and invasion enhancer 1 [Source:HGNC Symbol;Acc:HGNC:28230] | 1302 | 1.313 | 0.4118 | Yes |
| 17 | NLE1 | notchless homolog 1 [Source:HGNC Symbol;Acc:HGNC:19889] | 1599 | 1.145 | 0.4159 | Yes |
| 18 | SRCIN1 | SRC kinase signaling inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:29506] | 1694 | 1.095 | 0.4249 | Yes |
| 19 | C17orf50 | chromosome 17 open reading frame 50 [Source:HGNC Symbol;Acc:HGNC:29581] | 1842 | 1.018 | 0.4317 | Yes |
| 20 | YWHAEP7 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:49437] | 2036 | 0.927 | 0.4363 | Yes |
| 21 | UNC45B | unc-45 myosin chaperone B [Source:HGNC Symbol;Acc:HGNC:14304] | 2272 | 0.827 | 0.4386 | Yes |
| 22 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 2431 | 0.768 | 0.4425 | Yes |
| 23 | HEATR9 | HEAT repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:26548] | 2555 | 0.725 | 0.4468 | Yes |
| 24 | SNORD7 | small nucleolar RNA, C/D box 7 [Source:HGNC Symbol;Acc:HGNC:32704] | 2604 | 0.707 | 0.4530 | Yes |
| 25 | LIG3 | DNA ligase 3 [Source:HGNC Symbol;Acc:HGNC:6600] | 2739 | 0.666 | 0.4564 | Yes |
| 26 | TCAP | titin-cap [Source:HGNC Symbol;Acc:HGNC:11610] | 3323 | 0.523 | 0.4461 | Yes |
| 27 | ZNF830 | zinc finger protein 830 [Source:HGNC Symbol;Acc:HGNC:28291] | 3359 | 0.516 | 0.4506 | Yes |
| 28 | AP2B1 | adaptor related protein complex 2 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:563] | 3388 | 0.509 | 0.4553 | Yes |
| 29 | DHRS11 | dehydrogenase/reductase 11 [Source:HGNC Symbol;Acc:HGNC:28639] | 3394 | 0.507 | 0.4605 | Yes |
| 30 | MYO19 | myosin XIX [Source:HGNC Symbol;Acc:HGNC:26234] | 3441 | 0.497 | 0.4645 | Yes |
| 31 | PSMB3 | proteasome 20S subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:9540] | 3517 | 0.476 | 0.4675 | Yes |
| 32 | PEX12 | peroxisomal biogenesis factor 12 [Source:HGNC Symbol;Acc:HGNC:8854] | 3544 | 0.471 | 0.4718 | Yes |
| 33 | E2F3P1 | E2F transcription factor 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:3116] | 3854 | 0.410 | 0.4678 | No |
| 34 | PIGW | phosphatidylinositol glycan anchor biosynthesis class W [Source:HGNC Symbol;Acc:HGNC:23213] | 4348 | 0.307 | 0.4577 | No |
| 35 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 4972 | 0.184 | 0.4427 | No |
| 36 | AATF | apoptosis antagonizing transcription factor [Source:HGNC Symbol;Acc:HGNC:19235] | 5269 | 0.136 | 0.4362 | No |
| 37 | FBXO47 | F-box protein 47 [Source:HGNC Symbol;Acc:HGNC:31969] | 5382 | 0.113 | 0.4343 | No |
| 38 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6011 | 0.000 | 0.4173 | No |
| 39 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6012 | 0.000 | 0.4173 | No |
| 40 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6013 | 0.000 | 0.4173 | No |
| 41 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6033 | 0.000 | 0.4168 | No |
| 42 | CCL16 | C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614] | 6036 | 0.000 | 0.4168 | No |
| 43 | CCL15 | C-C motif chemokine ligand 15 [Source:HGNC Symbol;Acc:HGNC:10613] | 6038 | 0.000 | 0.4167 | No |
| 44 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6042 | 0.000 | 0.4167 | No |
| 45 | TBC1D3 | TBC1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:19031] | 7213 | 0.000 | 0.3850 | No |
| 46 | LYZL6 | lysozyme like 6 [Source:HGNC Symbol;Acc:HGNC:29614] | 7524 | 0.000 | 0.3766 | No |
| 47 | ASIC2 | acid sensing ion channel subunit 2 [Source:HGNC Symbol;Acc:HGNC:99] | 7576 | 0.000 | 0.3752 | No |
| 48 | MIR2909 | microRNA 2909 [Source:HGNC Symbol;Acc:HGNC:38372] | 8766 | 0.000 | 0.3431 | No |
| 49 | RASL10B | RAS like family 10 member B [Source:HGNC Symbol;Acc:HGNC:30295] | 9512 | 0.000 | 0.3229 | No |
| 50 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 9577 | 0.000 | 0.3212 | No |
| 51 | AA06 | uncharacterized LOC100506677 [Source:NCBI gene (formerly Entrezgene);Acc:100506677] | 9880 | 0.000 | 0.3130 | No |
| 52 | PNMT | phenylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:9160] | 10263 | 0.000 | 0.3027 | No |
| 53 | C17orf78 | chromosome 17 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:26831] | 11454 | 0.000 | 0.2705 | No |
| 54 | C17orf98 | chromosome 17 open reading frame 98 [Source:HGNC Symbol;Acc:HGNC:34492] | 11476 | 0.000 | 0.2699 | No |
| 55 | ERBB2 | erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430] | 11719 | 0.000 | 0.2634 | No |
| 56 | SNHG30 | small nucleolar RNA host gene 30 [Source:HGNC Symbol;Acc:HGNC:52836] | 11920 | 0.000 | 0.2580 | No |
| 57 | SLFN14 | schlafen family member 14 [Source:HGNC Symbol;Acc:HGNC:32689] | 11980 | 0.000 | 0.2564 | No |
| 58 | LHX1 | LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6593] | 12181 | 0.000 | 0.2509 | No |
| 59 | TOMM20P2 | TOMM20 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:50519] | 12476 | 0.000 | 0.2430 | No |
| 60 | RNU6-1192P | RNA, U6 small nuclear 1192, pseudogene [Source:HGNC Symbol;Acc:HGNC:48155] | 12724 | 0.000 | 0.2363 | No |
| 61 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14586 | 0.000 | 0.1860 | No |
| 62 | SLC35G3 | solute carrier family 35 member G3 [Source:HGNC Symbol;Acc:HGNC:26848] | 15862 | 0.000 | 0.1515 | No |
| 63 | RN7SL301P | RNA, 7SL, cytoplasmic 301, pseudogene [Source:HGNC Symbol;Acc:HGNC:46317] | 15939 | 0.000 | 0.1494 | No |
| 64 | SNORA21 | small nucleolar RNA, H/ACA box 21 [Source:HGNC Symbol;Acc:HGNC:32611] | 16015 | 0.000 | 0.1474 | No |
| 65 | C17orf102 | chromosome 17 open reading frame 102 [Source:HGNC Symbol;Acc:HGNC:34412] | 16502 | 0.000 | 0.1342 | No |
| 66 | RNU6-866P | RNA, U6 small nuclear 866, pseudogene [Source:HGNC Symbol;Acc:HGNC:47829] | 17002 | 0.000 | 0.1207 | No |
| 67 | RNA5SP440 | RNA, 5S ribosomal pseudogene 440 [Source:HGNC Symbol;Acc:HGNC:43340] | 17228 | 0.000 | 0.1146 | No |
| 68 | RNA5SP439 | RNA, 5S ribosomal pseudogene 439 [Source:HGNC Symbol;Acc:HGNC:43339] | 17264 | 0.000 | 0.1137 | No |
| 69 | RNA5SP438 | RNA, 5S ribosomal pseudogene 438 [Source:HGNC Symbol;Acc:HGNC:43338] | 17265 | 0.000 | 0.1137 | No |
| 70 | CCL15-CCL14 | CCL15-CCL14 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44436] | 17379 | 0.000 | 0.1106 | No |
| 71 | HNF1B | HNF1 homeobox B [Source:HGNC Symbol;Acc:HGNC:11630] | 17539 | 0.000 | 0.1063 | No |
| 72 | PPP1R1B | protein phosphatase 1 regulatory inhibitor subunit 1B [Source:HGNC Symbol;Acc:HGNC:9287] | 17582 | 0.000 | 0.1052 | No |
| 73 | LRRC37A9P | leucine rich repeat containing 37 member A9, pseudogene [Source:HGNC Symbol;Acc:HGNC:43813] | 17627 | 0.000 | 0.1040 | No |
| 74 | RNU6-489P | RNA, U6 small nuclear 489, pseudogene [Source:HGNC Symbol;Acc:HGNC:47452] | 18421 | 0.000 | 0.0825 | No |
| 75 | RNU6-233P | RNA, U6 small nuclear 233, pseudogene [Source:HGNC Symbol;Acc:HGNC:47196] | 18830 | 0.000 | 0.0715 | No |
| 76 | NEUROD2 | neuronal differentiation 2 [Source:HGNC Symbol;Acc:HGNC:7763] | 19183 | 0.000 | 0.0620 | No |
| 77 | LINC01989 | long intergenic non-protein coding RNA 1989 [Source:HGNC Symbol;Acc:HGNC:52821] | 20325 | 0.000 | 0.0311 | No |
| 78 | LINC02079 | long intergenic non-protein coding RNA 2079 [Source:HGNC Symbol;Acc:HGNC:52927] | 21549 | 0.000 | -0.0020 | No |
| 79 | TBC1D3K | TBC1 domain family member 3K [Source:HGNC Symbol;Acc:HGNC:51245] | 22188 | 0.000 | -0.0192 | No |
| 80 | TBC1D3L | TBC1 domain family member 3L [Source:HGNC Symbol;Acc:HGNC:51246] | 22189 | 0.000 | -0.0192 | No |
| 81 | TBC1D3B | TBC1 domain family member 3B [Source:HGNC Symbol;Acc:HGNC:27011] | 22195 | 0.000 | -0.0194 | No |
| 82 | TBC1D3E | TBC1 domain family member 3E [Source:HGNC Symbol;Acc:HGNC:27071] | 22197 | 0.000 | -0.0194 | No |
| 83 | TBC1D3F | TBC1 domain family member 3F [Source:HGNC Symbol;Acc:HGNC:18257] | 22198 | 0.000 | -0.0194 | No |
| 84 | TBC1D3C | TBC1 domain family member 3C [Source:HGNC Symbol;Acc:HGNC:24889] | 22200 | 0.000 | -0.0194 | No |
| 85 | TBC1D3D | TBC1 domain family member 3D [Source:HGNC Symbol;Acc:HGNC:28944] | 22201 | 0.000 | -0.0194 | No |
| 86 | TBC1D3I | TBC1 domain family member 3I [Source:HGNC Symbol;Acc:HGNC:32709] | 22202 | 0.000 | -0.0194 | No |
| 87 | TBC1D3J | TBC1 domain family member 3J [Source:HGNC Symbol;Acc:HGNC:51247] | 22204 | 0.000 | -0.0195 | No |
| 88 | TBC1D3G | TBC1 domain family member 3G [Source:HGNC Symbol;Acc:HGNC:29860] | 22206 | 0.000 | -0.0195 | No |
| 89 | TBC1D3H | TBC1 domain family member 3H [Source:HGNC Symbol;Acc:HGNC:30708] | 22207 | 0.000 | -0.0195 | No |
| 90 | TMEM132E | transmembrane protein 132E [Source:HGNC Symbol;Acc:HGNC:26991] | 22441 | 0.000 | -0.0258 | No |
| 91 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22826 | 0.000 | -0.0362 | No |
| 92 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 22828 | 0.000 | -0.0362 | No |
| 93 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22836 | 0.000 | -0.0364 | No |
| 94 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 22837 | 0.000 | -0.0364 | No |
| 95 | FNDC8 | fibronectin type III domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25286] | 25707 | 0.000 | -0.1140 | No |
| 96 | RNU6-840P | RNA, U6 small nuclear 840, pseudogene [Source:HGNC Symbol;Acc:HGNC:47803] | 25814 | 0.000 | -0.1169 | No |
| 97 | GAS2L2 | growth arrest specific 2 like 2 [Source:HGNC Symbol;Acc:HGNC:24846] | 26649 | 0.000 | -0.1395 | No |
| 98 | MIR4734 | microRNA 4734 [Source:HGNC Symbol;Acc:HGNC:41572] | 27082 | 0.000 | -0.1512 | No |
| 99 | MIR4726 | microRNA 4726 [Source:HGNC Symbol;Acc:HGNC:41722] | 27101 | 0.000 | -0.1516 | No |
| 100 | MIR4728 | microRNA 4728 [Source:HGNC Symbol;Acc:HGNC:41632] | 27104 | 0.000 | -0.1517 | No |
| 101 | MIR4727 | microRNA 4727 [Source:HGNC Symbol;Acc:HGNC:41709] | 27105 | 0.000 | -0.1517 | No |
| 102 | LRRC37A11P | leucine rich repeat containing 37 member A11, pseudogene [Source:HGNC Symbol;Acc:HGNC:43815] | 27362 | 0.000 | -0.1586 | No |
| 103 | GGNBP2 | gametogenetin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19357] | 27982 | -0.100 | -0.1743 | No |
| 104 | RPL23 | ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316] | 28124 | -0.122 | -0.1768 | No |
| 105 | TAF15 | TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547] | 28407 | -0.165 | -0.1827 | No |
| 106 | ARHGAP23 | Rho GTPase activating protein 23 [Source:HGNC Symbol;Acc:HGNC:29293] | 29021 | -0.252 | -0.1966 | No |
| 107 | RPL19 | ribosomal protein L19 [Source:HGNC Symbol;Acc:HGNC:10312] | 29023 | -0.253 | -0.1940 | No |
| 108 | MLLT6 | MLLT6, PHD finger containing [Source:HGNC Symbol;Acc:HGNC:7138] | 29065 | -0.259 | -0.1924 | No |
| 109 | ZNHIT3 | zinc finger HIT-type containing 3 [Source:HGNC Symbol;Acc:HGNC:12309] | 29543 | -0.332 | -0.2018 | No |
| 110 | SOCS7 | suppressor of cytokine signaling 7 [Source:HGNC Symbol;Acc:HGNC:29846] | 30057 | -0.407 | -0.2113 | No |
| 111 | ARL5C | ADP ribosylation factor like GTPase 5C [Source:HGNC Symbol;Acc:HGNC:31111] | 30755 | -0.519 | -0.2247 | No |
| 112 | PGAP3 | post-GPI attachment to proteins phospholipase 3 [Source:HGNC Symbol;Acc:HGNC:23719] | 31746 | -0.699 | -0.2441 | No |
| 113 | PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase type 2 beta [Source:HGNC Symbol;Acc:HGNC:8998] | 31960 | -0.744 | -0.2420 | No |
| 114 | RAD51D | RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823] | 32290 | -0.836 | -0.2421 | No |
| 115 | MMP28 | matrix metallopeptidase 28 [Source:HGNC Symbol;Acc:HGNC:14366] | 32702 | -0.947 | -0.2432 | No |
| 116 | SYNRG | synergin gamma [Source:HGNC Symbol;Acc:HGNC:557] | 33004 | -1.039 | -0.2403 | No |
| 117 | EPOP | elongin BC and polycomb repressive complex 2 associated protein [Source:HGNC Symbol;Acc:HGNC:34493] | 33148 | -1.077 | -0.2328 | No |
| 118 | HMGB1P24 | high mobility group box 1 pseudogene 24 [Source:HGNC Symbol;Acc:HGNC:39115] | 33550 | -1.211 | -0.2309 | No |
| 119 | CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:1401] | 33730 | -1.276 | -0.2222 | No |
| 120 | ACACA | acetyl-CoA carboxylase alpha [Source:HGNC Symbol;Acc:HGNC:84] | 34045 | -1.384 | -0.2161 | No |
| 121 | MRM1 | mitochondrial rRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26202] | 34049 | -1.387 | -0.2015 | No |
| 122 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 34126 | -1.416 | -0.1886 | No |
| 123 | LINC00672 | long intergenic non-protein coding RNA 672 [Source:HGNC Symbol;Acc:HGNC:44353] | 34694 | -1.647 | -0.1865 | No |
| 124 | CISD3 | CDGSH iron sulfur domain 3 [Source:HGNC Symbol;Acc:HGNC:27578] | 35137 | -1.891 | -0.1785 | No |
| 125 | DDX52 | DExD-box helicase 52 [Source:HGNC Symbol;Acc:HGNC:20038] | 35237 | -1.956 | -0.1605 | No |
| 126 | GPR179 | G protein-coupled receptor 179 [Source:HGNC Symbol;Acc:HGNC:31371] | 35661 | -2.240 | -0.1483 | No |
| 127 | PLXDC1 | plexin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20945] | 35834 | -2.405 | -0.1275 | No |
| 128 | TADA2A | transcriptional adaptor 2A [Source:HGNC Symbol;Acc:HGNC:11531] | 35964 | -2.516 | -0.1044 | No |
| 129 | RDM1 | RAD52 motif containing 1 [Source:HGNC Symbol;Acc:HGNC:19950] | 36064 | -2.623 | -0.0794 | No |
| 130 | STAC2 | SH3 and cysteine rich domain 2 [Source:HGNC Symbol;Acc:HGNC:23990] | 36220 | -2.771 | -0.0543 | No |
| 131 | PCGF2 | polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929] | 36765 | -3.542 | -0.0316 | No |
| 132 | FBXL20 | F-box and leucine rich repeat protein 20 [Source:HGNC Symbol;Acc:HGNC:24679] | 36871 | -3.814 | 0.0059 | No |
