Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | CROONQUIST_IL6_DEPRIVATION_DN |
| Enrichment Score (ES) | -0.81856656 |
| Normalized Enrichment Score (NES) | -1.6651373 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0012432993 |
| FWER p-Value | 0.025 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 171 | 3.617 | 0.0137 | No |
| 2 | RRP12 | ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100] | 596 | 2.140 | 0.0130 | No |
| 3 | ABHD5 | abhydrolase domain containing 5, lysophosphatidic acid acyltransferase [Source:HGNC Symbol;Acc:HGNC:21396] | 1340 | 1.286 | -0.0005 | No |
| 4 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 1675 | 1.104 | -0.0040 | No |
| 5 | HMGA1 | high mobility group AT-hook 1 [Source:HGNC Symbol;Acc:HGNC:5010] | 1779 | 1.048 | -0.0015 | No |
| 6 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 2428 | 0.770 | -0.0151 | No |
| 7 | PTPRC | protein tyrosine phosphatase receptor type C [Source:HGNC Symbol;Acc:HGNC:9666] | 4808 | 0.217 | -0.0783 | No |
| 8 | SNRPA1 | small nuclear ribonucleoprotein polypeptide A' [Source:HGNC Symbol;Acc:HGNC:11152] | 5221 | 0.147 | -0.0887 | No |
| 9 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 5375 | 0.114 | -0.0922 | No |
| 10 | AASS | aminoadipate-semialdehyde synthase [Source:HGNC Symbol;Acc:HGNC:17366] | 10164 | 0.000 | -0.2217 | No |
| 11 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12314 | 0.000 | -0.2797 | No |
| 12 | FRZB | frizzled related protein [Source:HGNC Symbol;Acc:HGNC:3959] | 16682 | 0.000 | -0.3978 | No |
| 13 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 23956 | 0.000 | -0.5944 | No |
| 14 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 26019 | 0.000 | -0.6501 | No |
| 15 | GGH | gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] | 27673 | -0.057 | -0.6945 | No |
| 16 | CDC25A | cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725] | 29004 | -0.250 | -0.7292 | No |
| 17 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 29048 | -0.257 | -0.7291 | No |
| 18 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 29854 | -0.377 | -0.7489 | No |
| 19 | GMPS | guanine monophosphate synthase [Source:HGNC Symbol;Acc:HGNC:4378] | 30718 | -0.514 | -0.7696 | No |
| 20 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 30719 | -0.514 | -0.7670 | No |
| 21 | H2BC11 | H2B clustered histone 11 [Source:HGNC Symbol;Acc:HGNC:4761] | 30832 | -0.531 | -0.7674 | No |
| 22 | SEPHS1 | selenophosphate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:19685] | 31891 | -0.729 | -0.7923 | No |
| 23 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32418 | -0.869 | -0.8021 | No |
| 24 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 32734 | -0.955 | -0.8058 | No |
| 25 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32753 | -0.958 | -0.8014 | No |
| 26 | CHAF1A | chromatin assembly factor 1 subunit A [Source:HGNC Symbol;Acc:HGNC:1910] | 33107 | -1.065 | -0.8056 | No |
| 27 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33208 | -1.098 | -0.8027 | No |
| 28 | ITM2A | integral membrane protein 2A [Source:HGNC Symbol;Acc:HGNC:6173] | 33406 | -1.161 | -0.8022 | No |
| 29 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 34013 | -1.377 | -0.8116 | Yes |
| 30 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 34095 | -1.401 | -0.8067 | Yes |
| 31 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34312 | -1.491 | -0.8050 | Yes |
| 32 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 34335 | -1.502 | -0.7980 | Yes |
| 33 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34381 | -1.518 | -0.7915 | Yes |
| 34 | SPOUT1 | SPOUT domain containing methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26933] | 34505 | -1.565 | -0.7869 | Yes |
| 35 | KNTC1 | kinetochore associated 1 [Source:HGNC Symbol;Acc:HGNC:17255] | 34562 | -1.584 | -0.7804 | Yes |
| 36 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34638 | -1.617 | -0.7743 | Yes |
| 37 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34684 | -1.643 | -0.7672 | Yes |
| 38 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34837 | -1.712 | -0.7626 | Yes |
| 39 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 34884 | -1.741 | -0.7551 | Yes |
| 40 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35062 | -1.840 | -0.7506 | Yes |
| 41 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35064 | -1.841 | -0.7413 | Yes |
| 42 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 35101 | -1.865 | -0.7328 | Yes |
| 43 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 35131 | -1.888 | -0.7240 | Yes |
| 44 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35138 | -1.892 | -0.7146 | Yes |
| 45 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 35199 | -1.931 | -0.7065 | Yes |
| 46 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35217 | -1.946 | -0.6971 | Yes |
| 47 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35290 | -1.989 | -0.6890 | Yes |
| 48 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35380 | -2.050 | -0.6810 | Yes |
| 49 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35407 | -2.067 | -0.6713 | Yes |
| 50 | STIL | STIL centriolar assembly protein [Source:HGNC Symbol;Acc:HGNC:10879] | 35542 | -2.150 | -0.6640 | Yes |
| 51 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 35605 | -2.200 | -0.6546 | Yes |
| 52 | BRCA1 | BRCA1 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1100] | 35708 | -2.283 | -0.6458 | Yes |
| 53 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35759 | -2.331 | -0.6353 | Yes |
| 54 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 35776 | -2.350 | -0.6239 | Yes |
| 55 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35813 | -2.385 | -0.6128 | Yes |
| 56 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 35933 | -2.484 | -0.6035 | Yes |
| 57 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35941 | -2.490 | -0.5910 | Yes |
| 58 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35993 | -2.546 | -0.5795 | Yes |
| 59 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36125 | -2.680 | -0.5695 | Yes |
| 60 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 36138 | -2.694 | -0.5562 | Yes |
| 61 | TRAIP | TRAF interacting protein [Source:HGNC Symbol;Acc:HGNC:30764] | 36174 | -2.734 | -0.5433 | Yes |
| 62 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36191 | -2.745 | -0.5299 | Yes |
| 63 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36199 | -2.753 | -0.5162 | Yes |
| 64 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36239 | -2.787 | -0.5031 | Yes |
| 65 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36260 | -2.803 | -0.4895 | Yes |
| 66 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 36274 | -2.821 | -0.4756 | Yes |
| 67 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36350 | -2.926 | -0.4628 | Yes |
| 68 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 36361 | -2.936 | -0.4482 | Yes |
| 69 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36367 | -2.940 | -0.4335 | Yes |
| 70 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 36391 | -2.970 | -0.4191 | Yes |
| 71 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36461 | -3.062 | -0.4055 | Yes |
| 72 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 36466 | -3.065 | -0.3901 | Yes |
| 73 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36476 | -3.083 | -0.3747 | Yes |
| 74 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36502 | -3.111 | -0.3596 | Yes |
| 75 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36508 | -3.121 | -0.3440 | Yes |
| 76 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36511 | -3.130 | -0.3282 | Yes |
| 77 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36546 | -3.187 | -0.3130 | Yes |
| 78 | GALK1 | galactokinase 1 [Source:HGNC Symbol;Acc:HGNC:4118] | 36553 | -3.194 | -0.2970 | Yes |
| 79 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36575 | -3.228 | -0.2813 | Yes |
| 80 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36576 | -3.229 | -0.2649 | Yes |
| 81 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 36617 | -3.295 | -0.2493 | Yes |
| 82 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36660 | -3.369 | -0.2334 | Yes |
| 83 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36698 | -3.424 | -0.2171 | Yes |
| 84 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36700 | -3.426 | -0.1998 | Yes |
| 85 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36709 | -3.440 | -0.1826 | Yes |
| 86 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36710 | -3.442 | -0.1652 | Yes |
| 87 | GALE | UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116] | 36720 | -3.454 | -0.1480 | Yes |
| 88 | PTP4A3 | protein tyrosine phosphatase 4A3 [Source:HGNC Symbol;Acc:HGNC:9636] | 36735 | -3.479 | -0.1308 | Yes |
| 89 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36780 | -3.580 | -0.1139 | Yes |
| 90 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36808 | -3.649 | -0.0961 | Yes |
| 91 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36828 | -3.703 | -0.0779 | Yes |
| 92 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36844 | -3.755 | -0.0593 | Yes |
| 93 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36939 | -3.976 | -0.0418 | Yes |
| 94 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 37029 | -4.385 | -0.0220 | Yes |
| 95 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37070 | -4.666 | 0.0005 | Yes |
