Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN |
| Enrichment Score (ES) | 0.8722235 |
| Normalized Enrichment Score (NES) | 2.1602788 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.994 | 0.0221 | Yes |
| 2 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 4 | 4.965 | 0.0440 | Yes |
| 3 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 6 | 4.951 | 0.0658 | Yes |
| 4 | ACOD1 | aconitate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:33904] | 7 | 4.944 | 0.0877 | Yes |
| 5 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 12 | 4.907 | 0.1093 | Yes |
| 6 | PHLDA1 | pleckstrin homology like domain family A member 1 [Source:HGNC Symbol;Acc:HGNC:8933] | 13 | 4.886 | 0.1309 | Yes |
| 7 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 30 | 4.738 | 0.1515 | Yes |
| 8 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 31 | 4.715 | 0.1723 | Yes |
| 9 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 34 | 4.688 | 0.1930 | Yes |
| 10 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 43 | 4.568 | 0.2130 | Yes |
| 11 | SOCS3 | suppressor of cytokine signaling 3 [Source:HGNC Symbol;Acc:HGNC:19391] | 45 | 4.558 | 0.2331 | Yes |
| 12 | TRAF1 | TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031] | 56 | 4.435 | 0.2525 | Yes |
| 13 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 74 | 4.266 | 0.2709 | Yes |
| 14 | ITGA5 | integrin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6141] | 80 | 4.202 | 0.2893 | Yes |
| 15 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 83 | 4.184 | 0.3078 | Yes |
| 16 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 87 | 4.161 | 0.3261 | Yes |
| 17 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 89 | 4.123 | 0.3443 | Yes |
| 18 | ADORA2B | adenosine A2b receptor [Source:HGNC Symbol;Acc:HGNC:264] | 106 | 4.008 | 0.3616 | Yes |
| 19 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 108 | 3.989 | 0.3792 | Yes |
| 20 | CD83 | CD83 molecule [Source:HGNC Symbol;Acc:HGNC:1703] | 109 | 3.980 | 0.3968 | Yes |
| 21 | PIM1 | Pim-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8986] | 111 | 3.966 | 0.4144 | Yes |
| 22 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 127 | 3.902 | 0.4312 | Yes |
| 23 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 130 | 3.895 | 0.4484 | Yes |
| 24 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 131 | 3.894 | 0.4656 | Yes |
| 25 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 140 | 3.826 | 0.4823 | Yes |
| 26 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 151 | 3.729 | 0.4985 | Yes |
| 27 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 156 | 3.689 | 0.5148 | Yes |
| 28 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 159 | 3.663 | 0.5309 | Yes |
| 29 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 171 | 3.617 | 0.5466 | Yes |
| 30 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 179 | 3.568 | 0.5622 | Yes |
| 31 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 180 | 3.568 | 0.5780 | Yes |
| 32 | TAPBP | TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566] | 215 | 3.342 | 0.5919 | Yes |
| 33 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 218 | 3.326 | 0.6065 | Yes |
| 34 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 226 | 3.286 | 0.6209 | Yes |
| 35 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 228 | 3.279 | 0.6353 | Yes |
| 36 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 241 | 3.211 | 0.6492 | Yes |
| 37 | PDLIM7 | PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958] | 243 | 3.206 | 0.6634 | Yes |
| 38 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 244 | 3.199 | 0.6775 | Yes |
| 39 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 251 | 3.171 | 0.6914 | Yes |
| 40 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 272 | 3.068 | 0.7044 | Yes |
| 41 | BCL2L11 | BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994] | 280 | 3.019 | 0.7176 | Yes |
| 42 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 296 | 2.957 | 0.7303 | Yes |
| 43 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 300 | 2.921 | 0.7431 | Yes |
| 44 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 313 | 2.870 | 0.7555 | Yes |
| 45 | PCDH7 | protocadherin 7 [Source:HGNC Symbol;Acc:HGNC:8659] | 319 | 2.842 | 0.7679 | Yes |
| 46 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 342 | 2.791 | 0.7797 | Yes |
| 47 | ACTG1 | actin gamma 1 [Source:HGNC Symbol;Acc:HGNC:144] | 354 | 2.739 | 0.7915 | Yes |
| 48 | IL18RAP | interleukin 18 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5989] | 356 | 2.733 | 0.8035 | Yes |
| 49 | ERRFI1 | ERBB receptor feedback inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:18185] | 376 | 2.691 | 0.8149 | Yes |
| 50 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 589 | 2.154 | 0.8187 | Yes |
| 51 | SRPRA | SRP receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:11307] | 592 | 2.149 | 0.8282 | Yes |
| 52 | HERPUD1 | homocysteine inducible ER protein with ubiquitin like domain 1 [Source:HGNC Symbol;Acc:HGNC:13744] | 651 | 2.040 | 0.8356 | Yes |
| 53 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 727 | 1.931 | 0.8422 | Yes |
| 54 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 761 | 1.874 | 0.8495 | Yes |
| 55 | IKBKE | inhibitor of nuclear factor kappa B kinase subunit epsilon [Source:HGNC Symbol;Acc:HGNC:14552] | 771 | 1.860 | 0.8575 | Yes |
| 56 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 850 | 1.758 | 0.8632 | Yes |
| 57 | RAC2 | Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802] | 1044 | 1.526 | 0.8647 | Yes |
| 58 | TSC22D1 | TSC22 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:16826] | 1100 | 1.468 | 0.8697 | Yes |
| 59 | BCL10 | BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989] | 1298 | 1.314 | 0.8702 | Yes |
| 60 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 1427 | 1.232 | 0.8722 | Yes |
| 61 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 1765 | 1.052 | 0.8678 | No |
| 62 | CDC42EP4 | CDC42 effector protein 4 [Source:HGNC Symbol;Acc:HGNC:17147] | 2805 | 0.647 | 0.8426 | No |
| 63 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 3735 | 0.433 | 0.8194 | No |
| 64 | UBB | ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463] | 3790 | 0.423 | 0.8198 | No |
| 65 | UBC | ubiquitin C [Source:HGNC Symbol;Acc:HGNC:12468] | 4861 | 0.207 | 0.7918 | No |
| 66 | VEGFA | vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680] | 5362 | 0.117 | 0.7788 | No |
| 67 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6042 | 0.000 | 0.7605 | No |
| 68 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8492 | 0.000 | 0.6943 | No |
| 69 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13283 | 0.000 | 0.5649 | No |
| 70 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19382 | 0.000 | 0.4001 | No |
| 71 | PLAUR | plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053] | 25527 | 0.000 | 0.2341 | No |
| 72 | PHLDB1 | pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697] | 29284 | -0.294 | 0.1339 | No |
| 73 | RREB1 | ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449] | 33069 | -1.052 | 0.0363 | No |
| 74 | PKM | pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] | 34421 | -1.534 | 0.0066 | No |
| 75 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141] | 34513 | -1.567 | 0.0111 | No |
| 76 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 34526 | -1.573 | 0.0177 | No |
| 77 | RHOB | ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668] | 34851 | -1.721 | 0.0166 | No |
| 78 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 35824 | -2.393 | 0.0009 | No |
| 79 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 36442 | -3.043 | -0.0023 | No |
| 80 | SCD | stearoyl-CoA desaturase [Source:HGNC Symbol;Acc:HGNC:10571] | 37047 | -4.472 | 0.0012 | No |
