Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | GHANDHI_BYSTANDER_IRRADIATION_UP |
| Enrichment Score (ES) | 0.80730534 |
| Normalized Enrichment Score (NES) | 2.0359578 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 0 | 4.995 | 0.0433 | Yes |
| 2 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.994 | 0.0865 | Yes |
| 3 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 4 | 4.965 | 0.1294 | Yes |
| 4 | DUSP5 | dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071] | 8 | 4.941 | 0.1721 | Yes |
| 5 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 10 | 4.932 | 0.2148 | Yes |
| 6 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 23 | 4.787 | 0.2559 | Yes |
| 7 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 30 | 4.738 | 0.2968 | Yes |
| 8 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 64 | 4.377 | 0.3338 | Yes |
| 9 | SLC7A11 | solute carrier family 7 member 11 [Source:HGNC Symbol;Acc:HGNC:11059] | 71 | 4.286 | 0.3708 | Yes |
| 10 | CREB5 | cAMP responsive element binding protein 5 [Source:HGNC Symbol;Acc:HGNC:16844] | 72 | 4.271 | 0.4078 | Yes |
| 11 | TNFSF15 | TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931] | 138 | 3.842 | 0.4393 | Yes |
| 12 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 151 | 3.729 | 0.4712 | Yes |
| 13 | OSGIN2 | oxidative stress induced growth inhibitor family member 2 [Source:HGNC Symbol;Acc:HGNC:1355] | 175 | 3.610 | 0.5019 | Yes |
| 14 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 176 | 3.589 | 0.5330 | Yes |
| 15 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 179 | 3.568 | 0.5638 | Yes |
| 16 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 216 | 3.338 | 0.5917 | Yes |
| 17 | POU2F2 | POU class 2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9213] | 269 | 3.083 | 0.6170 | Yes |
| 18 | AHR | aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348] | 353 | 2.741 | 0.6385 | Yes |
| 19 | SERPINB2 | serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584] | 396 | 2.630 | 0.6601 | Yes |
| 20 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 486 | 2.398 | 0.6785 | Yes |
| 21 | ZC3H12C | zinc finger CCCH-type containing 12C [Source:HGNC Symbol;Acc:HGNC:29362] | 674 | 1.998 | 0.6908 | Yes |
| 22 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 731 | 1.925 | 0.7059 | Yes |
| 23 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 802 | 1.811 | 0.7197 | Yes |
| 24 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 818 | 1.790 | 0.7348 | Yes |
| 25 | TUT7 | terminal uridylyl transferase 7 [Source:HGNC Symbol;Acc:HGNC:25817] | 873 | 1.728 | 0.7483 | Yes |
| 26 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 967 | 1.616 | 0.7598 | Yes |
| 27 | SLC39A14 | solute carrier family 39 member 14 [Source:HGNC Symbol;Acc:HGNC:20858] | 1073 | 1.497 | 0.7699 | Yes |
| 28 | DNAJB4 | DnaJ heat shock protein family (Hsp40) member B4 [Source:HGNC Symbol;Acc:HGNC:14886] | 1281 | 1.323 | 0.7758 | Yes |
| 29 | NAMPTP1 | nicotinamide phosphoribosyltransferase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:17633] | 1356 | 1.274 | 0.7848 | Yes |
| 30 | NAMPT | nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092] | 1406 | 1.243 | 0.7942 | Yes |
| 31 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 1509 | 1.184 | 0.8017 | Yes |
| 32 | MT1G | metallothionein 1G [Source:HGNC Symbol;Acc:HGNC:7399] | 1717 | 1.080 | 0.8055 | Yes |
| 33 | GADD45G | growth arrest and DNA damage inducible gamma [Source:HGNC Symbol;Acc:HGNC:4097] | 1959 | 0.964 | 0.8073 | Yes |
| 34 | PPP4R3B | protein phosphatase 4 regulatory subunit 3B [Source:HGNC Symbol;Acc:HGNC:29267] | 2403 | 0.777 | 0.8021 | No |
| 35 | C9orf72 | C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337] | 2593 | 0.711 | 0.8031 | No |
| 36 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 2766 | 0.661 | 0.8042 | No |
| 37 | MCTP1 | multiple C2 and transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26183] | 3041 | 0.594 | 0.8019 | No |
| 38 | PLEK2 | pleckstrin 2 [Source:HGNC Symbol;Acc:HGNC:19238] | 3225 | 0.546 | 0.8017 | No |
| 39 | ZSWIM8 | zinc finger SWIM-type containing 8 [Source:HGNC Symbol;Acc:HGNC:23528] | 3326 | 0.522 | 0.8035 | No |
| 40 | MT1E | metallothionein 1E [Source:HGNC Symbol;Acc:HGNC:7397] | 3493 | 0.483 | 0.8032 | No |
| 41 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 4573 | 0.262 | 0.7763 | No |
| 42 | RGS9 | regulator of G protein signaling 9 [Source:HGNC Symbol;Acc:HGNC:10004] | 4602 | 0.256 | 0.7778 | No |
| 43 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 4853 | 0.209 | 0.7728 | No |
| 44 | SLC39A8 | solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862] | 4859 | 0.207 | 0.7745 | No |
| 45 | MT1H | metallothionein 1H [Source:HGNC Symbol;Acc:HGNC:7400] | 4983 | 0.181 | 0.7728 | No |
| 46 | ATP6V1C1 | ATPase H+ transporting V1 subunit C1 [Source:HGNC Symbol;Acc:HGNC:856] | 5423 | 0.108 | 0.7618 | No |
| 47 | MCTP2 | multiple C2 and transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25636] | 7600 | 0.000 | 0.7030 | No |
| 48 | POPDC3 | popeye domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17649] | 8349 | 0.000 | 0.6828 | No |
| 49 | SLC16A6P1 | SLC16A6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:48932] | 10139 | 0.000 | 0.6345 | No |
| 50 | B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:15684] | 10456 | 0.000 | 0.6259 | No |
| 51 | SLC6A15 | solute carrier family 6 member 15 [Source:HGNC Symbol;Acc:HGNC:13621] | 11543 | 0.000 | 0.5966 | No |
| 52 | PTGFR | prostaglandin F receptor [Source:HGNC Symbol;Acc:HGNC:9600] | 11559 | 0.000 | 0.5962 | No |
| 53 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13668 | 0.000 | 0.5392 | No |
| 54 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:5208] | 14233 | 0.000 | 0.5240 | No |
| 55 | EPB41L4B | erythrocyte membrane protein band 4.1 like 4B [Source:HGNC Symbol;Acc:HGNC:19818] | 14883 | 0.000 | 0.5064 | No |
| 56 | PRR7-AS1 | PRR7 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27961] | 17041 | 0.000 | 0.4482 | No |
| 57 | SRSF12 | serine and arginine rich splicing factor 12 [Source:HGNC Symbol;Acc:HGNC:21220] | 17459 | 0.000 | 0.4369 | No |
| 58 | MMP1 | matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155] | 19032 | 0.000 | 0.3944 | No |
| 59 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19371 | 0.000 | 0.3853 | No |
| 60 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19380 | 0.000 | 0.3851 | No |
| 61 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19382 | 0.000 | 0.3850 | No |
| 62 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19384 | 0.000 | 0.3850 | No |
| 63 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 19782 | 0.000 | 0.3743 | No |
| 64 | IFNE | interferon epsilon [Source:HGNC Symbol;Acc:HGNC:18163] | 20745 | 0.000 | 0.3483 | No |
| 65 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 20835 | 0.000 | 0.3459 | No |
| 66 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 21932 | 0.000 | 0.3163 | No |
| 67 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 22010 | 0.000 | 0.3142 | No |
| 68 | CD69 | CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694] | 23006 | 0.000 | 0.2873 | No |
| 69 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 23589 | 0.000 | 0.2716 | No |
| 70 | C2CD4B | C2 calcium dependent domain containing 4B [Source:HGNC Symbol;Acc:HGNC:33628] | 24541 | 0.000 | 0.2459 | No |
| 71 | FGF2 | fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676] | 25249 | 0.000 | 0.2268 | No |
| 72 | STC1 | stanniocalcin 1 [Source:HGNC Symbol;Acc:HGNC:11373] | 27252 | 0.000 | 0.1727 | No |
| 73 | RELB | RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] | 28489 | -0.176 | 0.1408 | No |
| 74 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 29237 | -0.287 | 0.1231 | No |
| 75 | TESC | tescalcin [Source:HGNC Symbol;Acc:HGNC:26065] | 29278 | -0.293 | 0.1246 | No |
| 76 | IRAK3 | interleukin 1 receptor associated kinase 3 [Source:HGNC Symbol;Acc:HGNC:17020] | 29344 | -0.303 | 0.1254 | No |
| 77 | MT1B | metallothionein 1B [Source:HGNC Symbol;Acc:HGNC:7394] | 31168 | -0.589 | 0.0813 | No |
| 78 | PHEX | phosphate regulating endopeptidase homolog X-linked [Source:HGNC Symbol;Acc:HGNC:8918] | 31276 | -0.606 | 0.0836 | No |
| 79 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 32072 | -0.773 | 0.0688 | No |
| 80 | PLA2G4A | phospholipase A2 group IVA [Source:HGNC Symbol;Acc:HGNC:9035] | 32460 | -0.878 | 0.0660 | No |
| 81 | SLC16A6 | solute carrier family 16 member 6 [Source:HGNC Symbol;Acc:HGNC:10927] | 33609 | -1.234 | 0.0457 | No |
| 82 | RNF128 | ring finger protein 128 [Source:HGNC Symbol;Acc:HGNC:21153] | 35288 | -1.988 | 0.0175 | No |
| 83 | LRRC8B | leucine rich repeat containing 8 VRAC subunit B [Source:HGNC Symbol;Acc:HGNC:30692] | 36785 | -3.595 | 0.0082 | No |
