Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | HECKER_IFNB1_TARGETS |
| Enrichment Score (ES) | 0.882083 |
| Normalized Enrichment Score (NES) | 2.2281406 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 15 | 4.872 | 0.0326 | Yes |
| 2 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 17 | 4.863 | 0.0656 | Yes |
| 3 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 19 | 4.836 | 0.0984 | Yes |
| 4 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 20 | 4.828 | 0.1311 | Yes |
| 5 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 21 | 4.823 | 0.1638 | Yes |
| 6 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 29 | 4.760 | 0.1959 | Yes |
| 7 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 37 | 4.663 | 0.2274 | Yes |
| 8 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 46 | 4.543 | 0.2580 | Yes |
| 9 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 47 | 4.510 | 0.2885 | Yes |
| 10 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 54 | 4.451 | 0.3186 | Yes |
| 11 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 77 | 4.236 | 0.3467 | Yes |
| 12 | DDX58 | DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102] | 85 | 4.180 | 0.3749 | Yes |
| 13 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 94 | 4.083 | 0.4023 | Yes |
| 14 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 103 | 4.026 | 0.4294 | Yes |
| 15 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 110 | 3.966 | 0.4562 | Yes |
| 16 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 118 | 3.942 | 0.4827 | Yes |
| 17 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 124 | 3.916 | 0.5092 | Yes |
| 18 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 133 | 3.882 | 0.5353 | Yes |
| 19 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 145 | 3.779 | 0.5606 | Yes |
| 20 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 154 | 3.699 | 0.5855 | Yes |
| 21 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 168 | 3.624 | 0.6097 | Yes |
| 22 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 174 | 3.614 | 0.6341 | Yes |
| 23 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 177 | 3.589 | 0.6584 | Yes |
| 24 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 186 | 3.543 | 0.6822 | Yes |
| 25 | STAP1 | signal transducing adaptor family member 1 [Source:HGNC Symbol;Acc:HGNC:24133] | 191 | 3.499 | 0.7058 | Yes |
| 26 | DTX3L | deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323] | 193 | 3.490 | 0.7295 | Yes |
| 27 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 248 | 3.174 | 0.7495 | Yes |
| 28 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 276 | 3.036 | 0.7694 | Yes |
| 29 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 293 | 2.972 | 0.7891 | Yes |
| 30 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 302 | 2.917 | 0.8087 | Yes |
| 31 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 412 | 2.569 | 0.8232 | Yes |
| 32 | SH3BGRL2 | SH3 domain binding glutamate rich protein like 2 [Source:HGNC Symbol;Acc:HGNC:15567] | 673 | 1.999 | 0.8297 | Yes |
| 33 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 675 | 1.997 | 0.8432 | Yes |
| 34 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 774 | 1.859 | 0.8532 | Yes |
| 35 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 802 | 1.811 | 0.8647 | Yes |
| 36 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 1072 | 1.497 | 0.8676 | Yes |
| 37 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 1117 | 1.452 | 0.8763 | Yes |
| 38 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 1412 | 1.240 | 0.8767 | Yes |
| 39 | SCO2 | synthesis of cytochrome C oxidase 2 [Source:HGNC Symbol;Acc:HGNC:10604] | 1512 | 1.183 | 0.8821 | Yes |
| 40 | MYL9 | myosin light chain 9 [Source:HGNC Symbol;Acc:HGNC:15754] | 2334 | 0.801 | 0.8653 | No |
| 41 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 3415 | 0.501 | 0.8395 | No |
| 42 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 3728 | 0.434 | 0.8341 | No |
| 43 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 3891 | 0.402 | 0.8324 | No |
| 44 | HES4 | hes family bHLH transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:24149] | 6848 | 0.000 | 0.7525 | No |
| 45 | ARG1 | arginase 1 [Source:HGNC Symbol;Acc:HGNC:663] | 6950 | 0.000 | 0.7498 | No |
| 46 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7383 | 0.000 | 0.7381 | No |
| 47 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 8858 | 0.000 | 0.6983 | No |
| 48 | FCER1A | Fc fragment of IgE receptor Ia [Source:HGNC Symbol;Acc:HGNC:3609] | 9599 | 0.000 | 0.6783 | No |
| 49 | TYMP | thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148] | 9932 | 0.000 | 0.6693 | No |
| 50 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10224 | 0.000 | 0.6614 | No |
| 51 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 11887 | 0.000 | 0.6165 | No |
| 52 | APOBEC3A | apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343] | 12312 | 0.000 | 0.6050 | No |
| 53 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12314 | 0.000 | 0.6050 | No |
| 54 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 12913 | 0.000 | 0.5889 | No |
| 55 | GP9 | glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444] | 17065 | 0.000 | 0.4767 | No |
| 56 | SERPING1 | serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228] | 17713 | 0.000 | 0.4592 | No |
| 57 | SPON2 | spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253] | 18883 | 0.000 | 0.4276 | No |
| 58 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19371 | 0.000 | 0.4144 | No |
| 59 | HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 [Source:HGNC Symbol;Acc:HGNC:24368] | 19662 | 0.000 | 0.4066 | No |
| 60 | CHI3L1 | chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932] | 19771 | 0.000 | 0.4037 | No |
| 61 | C1QB | complement C1q B chain [Source:HGNC Symbol;Acc:HGNC:1242] | 20048 | 0.000 | 0.3962 | No |
| 62 | C1QA | complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241] | 20049 | 0.000 | 0.3962 | No |
| 63 | C1QC | complement C1q C chain [Source:HGNC Symbol;Acc:HGNC:1245] | 20065 | 0.000 | 0.3958 | No |
| 64 | FFAR2 | free fatty acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:4501] | 20626 | 0.000 | 0.3807 | No |
| 65 | IFI6 | interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] | 20640 | 0.000 | 0.3803 | No |
| 66 | MMP25 | matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246] | 20823 | 0.000 | 0.3754 | No |
| 67 | CMTM5 | CKLF like MARVEL transmembrane domain containing 5 [Source:HGNC Symbol;Acc:HGNC:19176] | 21968 | 0.000 | 0.3445 | No |
| 68 | CMTM2 | CKLF like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19173] | 21981 | 0.000 | 0.3441 | No |
| 69 | TRBV27 | T cell receptor beta variable 27 [Source:HGNC Symbol;Acc:HGNC:12208] | 22589 | 0.000 | 0.3277 | No |
| 70 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 22826 | 0.000 | 0.3214 | No |
| 71 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22836 | 0.000 | 0.3211 | No |
| 72 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 23094 | 0.000 | 0.3142 | No |
| 73 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 23524 | 0.000 | 0.3026 | No |
| 74 | KCNJ15 | potassium inwardly rectifying channel subfamily J member 15 [Source:HGNC Symbol;Acc:HGNC:6261] | 23735 | 0.000 | 0.2969 | No |
| 75 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 23816 | 0.000 | 0.2947 | No |
| 76 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 24394 | 0.000 | 0.2791 | No |
| 77 | CABP5 | calcium binding protein 5 [Source:HGNC Symbol;Acc:HGNC:13714] | 24657 | 0.000 | 0.2721 | No |
| 78 | ZBP1 | Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176] | 25780 | 0.000 | 0.2417 | No |
| 79 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 25904 | 0.000 | 0.2384 | No |
| 80 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 27136 | 0.000 | 0.2051 | No |
| 81 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 27646 | -0.053 | 0.1917 | No |
| 82 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 27941 | -0.095 | 0.1844 | No |
| 83 | RPS23 | ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:10410] | 27989 | -0.101 | 0.1839 | No |
| 84 | ITGA2B | integrin subunit alpha 2b [Source:HGNC Symbol;Acc:HGNC:6138] | 28602 | -0.188 | 0.1686 | No |
| 85 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 29237 | -0.287 | 0.1534 | No |
| 86 | TREML1 | triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434] | 29908 | -0.384 | 0.1379 | No |
| 87 | PROS1 | protein S [Source:HGNC Symbol;Acc:HGNC:9456] | 32570 | -0.905 | 0.0721 | No |
| 88 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 32733 | -0.955 | 0.0742 | No |
| 89 | JUP | junction plakoglobin [Source:HGNC Symbol;Acc:HGNC:6207] | 33483 | -1.184 | 0.0620 | No |
| 90 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 33826 | -1.312 | 0.0617 | No |
| 91 | CYP4F3 | cytochrome P450 family 4 subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:2646] | 33876 | -1.329 | 0.0694 | No |
| 92 | MGAM | maltase-glucoamylase [Source:HGNC Symbol;Acc:HGNC:7043] | 36026 | -2.579 | 0.0288 | No |
