Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | ISHIDA_E2F_TARGETS |
| Enrichment Score (ES) | -0.8758541 |
| Normalized Enrichment Score (NES) | -1.6712617 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0011150375 |
| FWER p-Value | 0.021 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ANXA8L1 | annexin A8 like 1 [Source:HGNC Symbol;Acc:HGNC:23334] | 22017 | 0.000 | -0.5944 | No |
| 2 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 30719 | -0.514 | -0.8253 | No |
| 3 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 30896 | -0.541 | -0.8259 | No |
| 4 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31383 | -0.630 | -0.8341 | No |
| 5 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32753 | -0.958 | -0.8636 | No |
| 6 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 33208 | -1.098 | -0.8673 | Yes |
| 7 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33397 | -1.158 | -0.8634 | Yes |
| 8 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 33412 | -1.163 | -0.8547 | Yes |
| 9 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 34095 | -1.401 | -0.8622 | Yes |
| 10 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34312 | -1.491 | -0.8565 | Yes |
| 11 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 34335 | -1.502 | -0.8454 | Yes |
| 12 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34381 | -1.518 | -0.8348 | Yes |
| 13 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35062 | -1.840 | -0.8389 | Yes |
| 14 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35064 | -1.841 | -0.8246 | Yes |
| 15 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35085 | -1.852 | -0.8107 | Yes |
| 16 | CDT1 | chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576] | 35143 | -1.895 | -0.7975 | Yes |
| 17 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 35148 | -1.896 | -0.7829 | Yes |
| 18 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35198 | -1.930 | -0.7692 | Yes |
| 19 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 35605 | -2.200 | -0.7630 | Yes |
| 20 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 35755 | -2.327 | -0.7490 | Yes |
| 21 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35759 | -2.331 | -0.7309 | Yes |
| 22 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35993 | -2.546 | -0.7174 | Yes |
| 23 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36065 | -2.624 | -0.6989 | Yes |
| 24 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 36076 | -2.633 | -0.6787 | Yes |
| 25 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36125 | -2.680 | -0.6592 | Yes |
| 26 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36251 | -2.795 | -0.6408 | Yes |
| 27 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36260 | -2.803 | -0.6193 | Yes |
| 28 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 36273 | -2.821 | -0.5977 | Yes |
| 29 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36357 | -2.930 | -0.5771 | Yes |
| 30 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36359 | -2.931 | -0.5544 | Yes |
| 31 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36367 | -2.940 | -0.5317 | Yes |
| 32 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36388 | -2.969 | -0.5091 | Yes |
| 33 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36461 | -3.062 | -0.4873 | Yes |
| 34 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36523 | -3.149 | -0.4644 | Yes |
| 35 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36546 | -3.187 | -0.4403 | Yes |
| 36 | LBR | lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518] | 36547 | -3.188 | -0.4155 | Yes |
| 37 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36575 | -3.228 | -0.3911 | Yes |
| 38 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36576 | -3.229 | -0.3660 | Yes |
| 39 | ANLN | anillin actin binding protein [Source:HGNC Symbol;Acc:HGNC:14082] | 36634 | -3.330 | -0.3416 | Yes |
| 40 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36660 | -3.369 | -0.3161 | Yes |
| 41 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36698 | -3.424 | -0.2905 | Yes |
| 42 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36710 | -3.442 | -0.2640 | Yes |
| 43 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36780 | -3.580 | -0.2381 | Yes |
| 44 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36784 | -3.594 | -0.2102 | Yes |
| 45 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36802 | -3.632 | -0.1824 | Yes |
| 46 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36817 | -3.672 | -0.1542 | Yes |
| 47 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36939 | -3.976 | -0.1266 | Yes |
| 48 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36947 | -3.999 | -0.0957 | Yes |
| 49 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36953 | -4.019 | -0.0646 | Yes |
| 50 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36976 | -4.107 | -0.0332 | Yes |
| 51 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37070 | -4.666 | 0.0005 | Yes |
