Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | KONG_E2F3_TARGETS |
| Enrichment Score (ES) | -0.8285865 |
| Normalized Enrichment Score (NES) | -1.7112072 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.9918798E-4 |
| FWER p-Value | 0.002 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | NR1D1 | nuclear receptor subfamily 1 group D member 1 [Source:HGNC Symbol;Acc:HGNC:7962] | 628 | 2.098 | -0.0061 | No |
| 2 | GAS5 | growth arrest specific 5 [Source:HGNC Symbol;Acc:HGNC:16355] | 665 | 2.018 | 0.0034 | No |
| 3 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 1270 | 1.333 | -0.0061 | No |
| 4 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 1753 | 1.057 | -0.0136 | No |
| 5 | TAL2 | TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557] | 1841 | 1.018 | -0.0107 | No |
| 6 | SRSF7 | serine and arginine rich splicing factor 7 [Source:HGNC Symbol;Acc:HGNC:10789] | 2138 | 0.881 | -0.0142 | No |
| 7 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 2431 | 0.768 | -0.0181 | No |
| 8 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 4667 | 0.241 | -0.0772 | No |
| 9 | NUP50 | nucleoporin 50 [Source:HGNC Symbol;Acc:HGNC:8065] | 4726 | 0.233 | -0.0776 | No |
| 10 | IGF2BP1 | insulin like growth factor 2 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:28866] | 5506 | 0.091 | -0.0982 | No |
| 11 | H4C15 | H4 clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:29607] | 12494 | 0.000 | -0.2871 | No |
| 12 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16648 | 0.000 | -0.3993 | No |
| 13 | PRL | prolactin [Source:HGNC Symbol;Acc:HGNC:9445] | 20036 | 0.000 | -0.4909 | No |
| 14 | PSORS1C2 | psoriasis susceptibility 1 candidate 2 [Source:HGNC Symbol;Acc:HGNC:17199] | 20702 | 0.000 | -0.5089 | No |
| 15 | F13A1 | coagulation factor XIII A chain [Source:HGNC Symbol;Acc:HGNC:3531] | 22725 | 0.000 | -0.5635 | No |
| 16 | GP1BA | glycoprotein Ib platelet subunit alpha [Source:HGNC Symbol;Acc:HGNC:4439] | 23138 | 0.000 | -0.5746 | No |
| 17 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 23982 | 0.000 | -0.5974 | No |
| 18 | MYB | MYB proto-oncogene, transcription factor [Source:HGNC Symbol;Acc:HGNC:7545] | 28441 | -0.170 | -0.7171 | No |
| 19 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 28935 | -0.239 | -0.7292 | No |
| 20 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29749 | -0.363 | -0.7493 | No |
| 21 | FBXO45 | F-box protein 45 [Source:HGNC Symbol;Acc:HGNC:29148] | 29863 | -0.377 | -0.7504 | No |
| 22 | MAPK8 | mitogen-activated protein kinase 8 [Source:HGNC Symbol;Acc:HGNC:6881] | 29911 | -0.385 | -0.7496 | No |
| 23 | RPL12 | ribosomal protein L12 [Source:HGNC Symbol;Acc:HGNC:10302] | 30324 | -0.449 | -0.7584 | No |
| 24 | TAF1D | TATA-box binding protein associated factor, RNA polymerase I subunit D [Source:HGNC Symbol;Acc:HGNC:28759] | 30592 | -0.493 | -0.7631 | No |
| 25 | RPRD1B | regulation of nuclear pre-mRNA domain containing 1B [Source:HGNC Symbol;Acc:HGNC:16209] | 31662 | -0.682 | -0.7885 | No |
| 26 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 32418 | -0.869 | -0.8044 | No |
| 27 | HLX | H2.0 like homeobox [Source:HGNC Symbol;Acc:HGNC:4978] | 33314 | -1.132 | -0.8227 | Yes |
| 28 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 33397 | -1.158 | -0.8189 | Yes |
| 29 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 33412 | -1.163 | -0.8133 | Yes |
| 30 | FAM111A | family with sequence similarity 111 member A [Source:HGNC Symbol;Acc:HGNC:24725] | 33488 | -1.187 | -0.8092 | Yes |
| 31 | RBBP8 | RB binding protein 8, endonuclease [Source:HGNC Symbol;Acc:HGNC:9891] | 33518 | -1.198 | -0.8038 | Yes |
| 32 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 33884 | -1.331 | -0.8068 | Yes |
| 33 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 33890 | -1.332 | -0.8000 | Yes |
| 34 | CENPQ | centromere protein Q [Source:HGNC Symbol;Acc:HGNC:21347] | 33909 | -1.339 | -0.7936 | Yes |
| 35 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34312 | -1.491 | -0.7967 | Yes |
| 36 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 34439 | -1.540 | -0.7921 | Yes |
| 37 | RBL1 | RB transcriptional corepressor like 1 [Source:HGNC Symbol;Acc:HGNC:9893] | 34459 | -1.548 | -0.7846 | Yes |
| 38 | RPL3 | ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10332] | 34647 | -1.624 | -0.7813 | Yes |
| 39 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34837 | -1.712 | -0.7775 | Yes |
| 40 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 34884 | -1.741 | -0.7698 | Yes |
| 41 | USP1 | ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607] | 35006 | -1.806 | -0.7637 | Yes |
| 42 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35062 | -1.840 | -0.7556 | Yes |
| 43 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35085 | -1.852 | -0.7467 | Yes |
| 44 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35198 | -1.930 | -0.7397 | Yes |
| 45 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 35199 | -1.931 | -0.7297 | Yes |
| 46 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 35290 | -1.989 | -0.7218 | Yes |
| 47 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 35318 | -2.003 | -0.7122 | Yes |
| 48 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35380 | -2.050 | -0.7032 | Yes |
| 49 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 35432 | -2.082 | -0.6938 | Yes |
| 50 | ERCC6L | ERCC excision repair 6 like, spindle assembly checkpoint helicase [Source:HGNC Symbol;Acc:HGNC:20794] | 35604 | -2.200 | -0.6871 | Yes |
| 51 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 35605 | -2.200 | -0.6757 | Yes |
| 52 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 35638 | -2.227 | -0.6650 | Yes |
| 53 | BRCA1 | BRCA1 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1100] | 35708 | -2.283 | -0.6551 | Yes |
| 54 | FIGNL1 | fidgetin like 1 [Source:HGNC Symbol;Acc:HGNC:13286] | 35714 | -2.288 | -0.6434 | Yes |
| 55 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35759 | -2.331 | -0.6325 | Yes |
| 56 | CBX2 | chromobox 2 [Source:HGNC Symbol;Acc:HGNC:1552] | 35846 | -2.418 | -0.6223 | Yes |
| 57 | DEPDC1 | DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949] | 35888 | -2.450 | -0.6107 | Yes |
| 58 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 35933 | -2.484 | -0.5991 | Yes |
| 59 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 35941 | -2.490 | -0.5864 | Yes |
| 60 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35981 | -2.530 | -0.5743 | Yes |
| 61 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35993 | -2.546 | -0.5614 | Yes |
| 62 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36065 | -2.624 | -0.5498 | Yes |
| 63 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 36068 | -2.625 | -0.5363 | Yes |
| 64 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 36069 | -2.626 | -0.5227 | Yes |
| 65 | NCAPG2 | non-SMC condensin II complex subunit G2 [Source:HGNC Symbol;Acc:HGNC:21904] | 36122 | -2.676 | -0.5102 | Yes |
| 66 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36125 | -2.680 | -0.4964 | Yes |
| 67 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36191 | -2.745 | -0.4840 | Yes |
| 68 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 36239 | -2.787 | -0.4708 | Yes |
| 69 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 36251 | -2.795 | -0.4566 | Yes |
| 70 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 36255 | -2.798 | -0.4422 | Yes |
| 71 | PSIP1 | PC4 and SFRS1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9527] | 36305 | -2.851 | -0.4288 | Yes |
| 72 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36342 | -2.919 | -0.4147 | Yes |
| 73 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 36357 | -2.930 | -0.3999 | Yes |
| 74 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36421 | -3.011 | -0.3860 | Yes |
| 75 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36439 | -3.036 | -0.3708 | Yes |
| 76 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36457 | -3.057 | -0.3554 | Yes |
| 77 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36461 | -3.062 | -0.3396 | Yes |
| 78 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 36473 | -3.076 | -0.3240 | Yes |
| 79 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36476 | -3.083 | -0.3081 | Yes |
| 80 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 36502 | -3.111 | -0.2927 | Yes |
| 81 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36511 | -3.130 | -0.2767 | Yes |
| 82 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 36519 | -3.139 | -0.2606 | Yes |
| 83 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36523 | -3.149 | -0.2444 | Yes |
| 84 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36546 | -3.187 | -0.2285 | Yes |
| 85 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36654 | -3.353 | -0.2141 | Yes |
| 86 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36660 | -3.369 | -0.1968 | Yes |
| 87 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36664 | -3.374 | -0.1794 | Yes |
| 88 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36691 | -3.417 | -0.1624 | Yes |
| 89 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36705 | -3.438 | -0.1449 | Yes |
| 90 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36709 | -3.440 | -0.1272 | Yes |
| 91 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36710 | -3.442 | -0.1094 | Yes |
| 92 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36780 | -3.580 | -0.0928 | Yes |
| 93 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36802 | -3.632 | -0.0745 | Yes |
| 94 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36817 | -3.672 | -0.0559 | Yes |
| 95 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 36827 | -3.702 | -0.0370 | Yes |
| 96 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36881 | -3.841 | -0.0185 | Yes |
| 97 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 37070 | -4.666 | 0.0005 | Yes |
