Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_NA |
| GeneSet | MORI_IMMATURE_B_LYMPHOCYTE_DN |
| Enrichment Score (ES) | -0.82739663 |
| Normalized Enrichment Score (NES) | -1.6859975 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.6411763E-4 |
| FWER p-Value | 0.01 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 985 | 1.591 | -0.0180 | No |
| 2 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 1270 | 1.333 | -0.0184 | No |
| 3 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] | 1963 | 0.962 | -0.0319 | No |
| 4 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 2574 | 0.721 | -0.0444 | No |
| 5 | PREP | prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358] | 3438 | 0.498 | -0.0650 | No |
| 6 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 4200 | 0.339 | -0.0838 | No |
| 7 | CBX1 | chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551] | 4640 | 0.245 | -0.0943 | No |
| 8 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 4667 | 0.241 | -0.0937 | No |
| 9 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12360 | 0.000 | -0.3016 | No |
| 10 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 12457 | 0.000 | -0.3042 | No |
| 11 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16648 | 0.000 | -0.4174 | No |
| 12 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18373 | 0.000 | -0.4640 | No |
| 13 | RAMP1 | receptor activity modifying protein 1 [Source:HGNC Symbol;Acc:HGNC:9843] | 20272 | 0.000 | -0.5153 | No |
| 14 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 23956 | 0.000 | -0.6149 | No |
| 15 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 27601 | -0.044 | -0.7131 | No |
| 16 | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100] | 28986 | -0.246 | -0.7492 | No |
| 17 | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [Source:HGNC Symbol;Acc:HGNC:11101] | 29371 | -0.307 | -0.7579 | No |
| 18 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 29510 | -0.329 | -0.7598 | No |
| 19 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29749 | -0.363 | -0.7643 | No |
| 20 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 29854 | -0.377 | -0.7650 | No |
| 21 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31383 | -0.630 | -0.8029 | No |
| 22 | HAUS3 | HAUS augmin like complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28719] | 31503 | -0.652 | -0.8026 | No |
| 23 | ACTN4 | actinin alpha 4 [Source:HGNC Symbol;Acc:HGNC:166] | 31834 | -0.712 | -0.8076 | No |
| 24 | HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:HGNC:24941] | 32257 | -0.827 | -0.8145 | No |
| 25 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 32734 | -0.955 | -0.8222 | Yes |
| 26 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32753 | -0.958 | -0.8175 | Yes |
| 27 | RBBP4 | RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887] | 33117 | -1.069 | -0.8215 | Yes |
| 28 | UCK2 | uridine-cytidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12562] | 33122 | -1.070 | -0.8158 | Yes |
| 29 | SLC16A1 | solute carrier family 16 member 1 [Source:HGNC Symbol;Acc:HGNC:10922] | 33222 | -1.103 | -0.8124 | Yes |
| 30 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 33508 | -1.194 | -0.8136 | Yes |
| 31 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 33741 | -1.280 | -0.8130 | Yes |
| 32 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 33916 | -1.342 | -0.8104 | Yes |
| 33 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 34140 | -1.424 | -0.8086 | Yes |
| 34 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 34312 | -1.491 | -0.8052 | Yes |
| 35 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 34335 | -1.502 | -0.7976 | Yes |
| 36 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 34381 | -1.518 | -0.7905 | Yes |
| 37 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 34409 | -1.530 | -0.7829 | Yes |
| 38 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 34439 | -1.540 | -0.7753 | Yes |
| 39 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 34638 | -1.617 | -0.7719 | Yes |
| 40 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 35062 | -1.840 | -0.7733 | Yes |
| 41 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35085 | -1.852 | -0.7638 | Yes |
| 42 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 35198 | -1.930 | -0.7564 | Yes |
| 43 | XRCC6 | X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055] | 35321 | -2.006 | -0.7488 | Yes |
| 44 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 35407 | -2.067 | -0.7398 | Yes |
| 45 | CKAP5 | cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:HGNC:28959] | 35408 | -2.067 | -0.7286 | Yes |
| 46 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 35480 | -2.112 | -0.7190 | Yes |
| 47 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 35605 | -2.200 | -0.7104 | Yes |
| 48 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 35638 | -2.227 | -0.6991 | Yes |
| 49 | TUBA1B | tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809] | 35701 | -2.280 | -0.6884 | Yes |
| 50 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35759 | -2.331 | -0.6773 | Yes |
| 51 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35813 | -2.385 | -0.6657 | Yes |
| 52 | CENPL | centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879] | 35885 | -2.448 | -0.6543 | Yes |
| 53 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35981 | -2.530 | -0.6431 | Yes |
| 54 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35993 | -2.546 | -0.6296 | Yes |
| 55 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 36065 | -2.624 | -0.6172 | Yes |
| 56 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 36076 | -2.633 | -0.6032 | Yes |
| 57 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36125 | -2.680 | -0.5899 | Yes |
| 58 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36129 | -2.683 | -0.5754 | Yes |
| 59 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 36146 | -2.702 | -0.5611 | Yes |
| 60 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 36199 | -2.753 | -0.5476 | Yes |
| 61 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 36260 | -2.803 | -0.5339 | Yes |
| 62 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 36274 | -2.821 | -0.5189 | Yes |
| 63 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 36350 | -2.926 | -0.5051 | Yes |
| 64 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 36359 | -2.931 | -0.4893 | Yes |
| 65 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36367 | -2.940 | -0.4735 | Yes |
| 66 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36426 | -3.017 | -0.4587 | Yes |
| 67 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36439 | -3.036 | -0.4425 | Yes |
| 68 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36457 | -3.057 | -0.4263 | Yes |
| 69 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 36461 | -3.062 | -0.4098 | Yes |
| 70 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 36476 | -3.083 | -0.3934 | Yes |
| 71 | PTGR1 | prostaglandin reductase 1 [Source:HGNC Symbol;Acc:HGNC:18429] | 36517 | -3.138 | -0.3774 | Yes |
| 72 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 36519 | -3.139 | -0.3603 | Yes |
| 73 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 36546 | -3.187 | -0.3437 | Yes |
| 74 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 36575 | -3.228 | -0.3269 | Yes |
| 75 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36576 | -3.229 | -0.3093 | Yes |
| 76 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36625 | -3.312 | -0.2926 | Yes |
| 77 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 36629 | -3.321 | -0.2746 | Yes |
| 78 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36635 | -3.330 | -0.2567 | Yes |
| 79 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36660 | -3.369 | -0.2390 | Yes |
| 80 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 36664 | -3.374 | -0.2207 | Yes |
| 81 | GSN | gelsolin [Source:HGNC Symbol;Acc:HGNC:4620] | 36666 | -3.381 | -0.2023 | Yes |
| 82 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36784 | -3.594 | -0.1860 | Yes |
| 83 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36802 | -3.632 | -0.1667 | Yes |
| 84 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36817 | -3.672 | -0.1471 | Yes |
| 85 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36841 | -3.749 | -0.1273 | Yes |
| 86 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36939 | -3.976 | -0.1083 | Yes |
| 87 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36953 | -4.019 | -0.0868 | Yes |
| 88 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36969 | -4.093 | -0.0649 | Yes |
| 89 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36976 | -4.107 | -0.0428 | Yes |
| 90 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36994 | -4.180 | -0.0205 | Yes |
| 91 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 37006 | -4.236 | 0.0023 | Yes |
