Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #KO_LPS_versus_KO_NA.Nof1.cls #KO_LPS_versus_KO_NA_repos |
| Phenotype | Nof1.cls#KO_LPS_versus_KO_NA_repos |
| Upregulated in class | KO_LPS |
| GeneSet | REACTOME_INTERLEUKIN_10_SIGNALING |
| Enrichment Score (ES) | 0.9075314 |
| Normalized Enrichment Score (NES) | 2.087286 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 0 | 4.995 | 0.0649 | Yes |
| 2 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 1 | 4.994 | 0.1297 | Yes |
| 3 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 4 | 4.965 | 0.1941 | Yes |
| 4 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 6 | 4.951 | 0.2584 | Yes |
| 5 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 10 | 4.932 | 0.3224 | Yes |
| 6 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 12 | 4.907 | 0.3860 | Yes |
| 7 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 26 | 4.768 | 0.4476 | Yes |
| 8 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 38 | 4.646 | 0.5076 | Yes |
| 9 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 39 | 4.636 | 0.5678 | Yes |
| 10 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 43 | 4.568 | 0.6271 | Yes |
| 11 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 127 | 3.902 | 0.6755 | Yes |
| 12 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 128 | 3.902 | 0.7262 | Yes |
| 13 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 234 | 3.248 | 0.7655 | Yes |
| 14 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 486 | 2.398 | 0.7899 | Yes |
| 15 | STAT3 | signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364] | 514 | 2.328 | 0.8194 | Yes |
| 16 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 776 | 1.858 | 0.8364 | Yes |
| 17 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 802 | 1.811 | 0.8593 | Yes |
| 18 | TNFRSF1A | TNF receptor superfamily member 1A [Source:HGNC Symbol;Acc:HGNC:11916] | 848 | 1.758 | 0.8809 | Yes |
| 19 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 850 | 1.758 | 0.9037 | Yes |
| 20 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 1387 | 1.254 | 0.9055 | Yes |
| 21 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1808 | 1.029 | 0.9075 | Yes |
| 22 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 2404 | 0.776 | 0.9015 | No |
| 23 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 2890 | 0.626 | 0.8966 | No |
| 24 | TYK2 | tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440] | 3309 | 0.525 | 0.8921 | No |
| 25 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 3611 | 0.456 | 0.8899 | No |
| 26 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 4606 | 0.254 | 0.8664 | No |
| 27 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 5174 | 0.156 | 0.8531 | No |
| 28 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 5331 | 0.124 | 0.8505 | No |
| 29 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 5390 | 0.110 | 0.8504 | No |
| 30 | IL10RB | interleukin 10 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:5965] | 5869 | 0.017 | 0.8377 | No |
| 31 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6032 | 0.000 | 0.8333 | No |
| 32 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6043 | 0.000 | 0.8330 | No |
| 33 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6046 | 0.000 | 0.8330 | No |
| 34 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14584 | 0.000 | 0.6025 | No |
| 35 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14586 | 0.000 | 0.6025 | No |
| 36 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15821 | 0.000 | 0.5692 | No |
| 37 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 15822 | 0.000 | 0.5692 | No |
| 38 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18189 | 0.000 | 0.5053 | No |
| 39 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19371 | 0.000 | 0.4734 | No |
| 40 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19380 | 0.000 | 0.4732 | No |
| 41 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 22836 | 0.000 | 0.3800 | No |
| 42 | CD80 | CD80 molecule [Source:HGNC Symbol;Acc:HGNC:1700] | 23011 | 0.000 | 0.3753 | No |
| 43 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 24383 | 0.000 | 0.3383 | No |
| 44 | FCER2 | Fc fragment of IgE receptor II [Source:HGNC Symbol;Acc:HGNC:3612] | 25910 | 0.000 | 0.2971 | No |
| 45 | IL12A | interleukin 12A [Source:HGNC Symbol;Acc:HGNC:5969] | 26839 | 0.000 | 0.2720 | No |
| 46 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 29732 | -0.360 | 0.1986 | No |
